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Comparative Effectiveness of Antidiabetic Therapies on Clinical Outcomes in Type 2 Diabetes Mellitus Outpatients Tandah, Muhamad Rinaldhi; Diana, Khusnul; Hidayat, Chairunisah; Ambianti, Nurul
Journal of Health and Nutrition Research Vol. 4 No. 2 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i2.481

Abstract

This study used observational analysis with retrospective data collection. A total of 303 outpatients with were included in this study. The research instrument used was secondary from medical record data and examination results of Fasting Plasma Glucose (FPG) and 2-hour plasma glucose (2-h PG) values when the patient first visited and the fourth month after the first visit. The patients' therapy is regarded as effective if the FPG test results range from 80-130 mg/dL and the 2-h PG test value is <180 mg/dL in the fourth month. In patients aged >60 years, it is said to be effective if the results of the FPG examination are around ≤ 180 mg/dL and the 2-h PG examination value is ≤200 mg/dL. Data were analyzed using Kruskal-Wallis analysis. Oral antidiabetics metformin and glimepiride had differences in observed effectiveness (p=0.000) < 0.05 for FPG and 2-h PG examinations in outpatients with type 2 diabetes mellitus. The type of oral antidiabetic glimepiride had differences in observed effectiveness (p=0.002) < 0.05 in the FPG examination and (p=0.006) < 0.05 in the 2-h PG examination. The oral antidiabetic drug groups metformin and glimepiride had differences in observed therapeutic effectiveness in outpatients with T2DM, while the insulin group and the combination group did not have differences in therapeutic effectiveness in T2DM patients.
EDUKASI OBAT RUSAK DAN KEDALUARSA PADA MASYARAKAT DESA TOSALE, KECAMATAN BANAWA SELATAN, KABUPATEN DONGGALA diana, khusnul; Rinaldhi Tandah, Muhamad; Ambianti, Nurul; Fadhilah Zainal, Setiawati
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 1 No. 1 (2022): Oktober 2022
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2022.v1.i1.16099

Abstract

Using damaged and expired drugs in the community can be a problem for health. Using medicines that have been damaged or drugs that have expired can be fatal, ranging from poisoning, and disability, to causing death. Many factors can cause damaged and expired drugs, both occurring in health facilities (such as pharmacies, hospitals, health centers, and distributors) or the storage of drug users in this case in the community. People as users of medicinal products sometimes do not know how the physical characteristics and signs of drugs are damaged and medicines that have expired. This community service activity was carried out in the Tosale Village area of ​​Donggala to assist the local community in knowing and recognizing drugs that were damaged or expired. This activity is carried out using lecture and discussion methods around recognizing the characteristics and signs of damaged and expired drugs, how to prevent the occurrence of damaged and expired drugs and how to store medicines to avoid damage. Evaluation of activities by giving short questions to participants about the material that has been given to identifying damaged and expired drugs. Active participants who answered correctly were given the appreciation in the form of mementos from the service team. This activity was completed by the target number of participants and the time given by the Tosale Village Head.
EDUKASI PENGELOLAAN OBAT RUSAK DAN KEDALUWARSA MENGGUNAKAN MEDIA LEAFLET DI DESA UENUNI, KECAMATAN PALOLO, KABUPATEN SIGI: Education on Management of Damaged and Expired Medicines Using Leaflet Media Diana, Khusnul; Ambianti, Nurul; Tandah, Muhamad Rinaldhi; Zainal, Setiawati Fadhilah
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 2 No. 1 (2023): Oktober 2023
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2023.v2.i1.16660

Abstract

Masyarakat memperoleh obat dari apotek atau fasilitas kesehatan akan menyimpan obat-obatannya di rumah untuk berbagai keperluan termasuk penggunaan darurat dan penyakit akut atau kronis. Kebanyakan obat-obatan yang di simpan di rumah akhirnya tidak digunakan dan menjadi kedaluwarsa. Kurangnya pengetahuan dan informasi terkait cara mengelola obat rusak dan obat kedaluwarsa mengakibatkan masyarakat melakukan praktik pembuangan obat yang tidak digunakan langsung ke tempat sampah umum. Hal ini akan menyebabkan permasalahan yang cukup besar dilingkungan masyarakat. Kegiatan pengabdian kepada masyarakat dilakukan di Desa Unenui Kecamatan Palolo Kabupaten Sigi. Secara tipologi dan geologi desa ini terletak di pegunungan, sehingga akses sarana fasilitas kesehatan dan tenaga kesehatan masih terbatas. Pengabdian ini bertujuan untuk membantu masyarakat dalam memahami dan meningkatkan pengetahuan terkait pengelolaan obat rusak dan kedaluwarsa. Kegiatan ini dilakukan dengan metode edukasi melalui upaya pemberian informasi dan pembagian leaflet tentang definisi obat rusak dan kedaluwarsa, penyebab dan ciri-ciri obat rusak, cara pengecekkan obat kedaluwarsa, serta cara memusnahkan obat rusak dan kedaluwarsa. Evaluasi kegiatan dengan memberikan pertanyaan singkat kepada peserta tentang isi materi pada leaflet. Kegiatan ini selesai dilaksanakan sesuai dengan target jumlah peserta dan waktu yang diberikan oleh Kepala Desa Uenuni.
KEGAGALAN PENGENDALIAN DIABETES MELLITUS TIPE II DITINJAU DARI FAKTOR PREDISPOSISI Khusnul Diana; Amalia Purnamasari Zainal; Setaiawati Fadhilah Zainal; Muhammad Rinaldhi Tandah; Dhea Puspita; Nurul Ambianti
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 10 No. 2 (2024): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v10i2.886

Abstract

Failure to control type II diabetes mellitus (DM) has a serious impact on the quality of life and health of DM patients. One of the factors that can influence the failure to control DM is predisposing factors. This study aims to determine predisposing factors including gender, education level, age, smoking, occupation, sports activities, long-suffering, knowledge, and behavior that influence failure to control type II DM. The research method used was descriptive analysis with cross-sectional data collection. This research used a purposive sampling technique and the patients used were 179 respondents. Data was collected using the Diabetes Knowledge Questionnaire (DKQ-24) questionnaire and the Self-Management Diabetes Mellitus (SMDM) questionnaire instrument. The data analysis used is bivariate and multivariate. The results of the bivariate analysis show that the variables that influence the failure to control Type II DM are the length of suffering (p = 0.000), behavior (p = 0.004), sports activities (p = 0.029), and work (p = 0.020). The results of the multivariate analysis of the dominant factors influencing failure to control type II DM are long-suffering with a value of OR = 6.956, behavior with a value of OR = 4.156, knowledge with a value of OR = 2.947, sports activities with a value of OR = 0.690, so it can be concluded that the variable long-suffering is The main factor in the failure to control type II DM because it can increase the risk of complications such as pancreatic cell damage and insulin resistance.
Analisis Efektivitas Biaya Penggunaan Antibiotik Levofloksasin dan Azitromisin pada Pasien Penderita Corona Virus Disease-19 pada Tahun 2021 di RSUD Madani Palu: Cost-Effectiveness Analysis of Levofloxacin and Azithromycin Antibiotics Usage in Patients with Corona Virus Disease-19 in 2021 at Madani Hospital in Palu Tandah, Muhamad Rinaldhi; Ririen Hardani; Nurhafifah Wulandari Kassa; Nurul Ambianti
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 6 No. 7 (2023): July 2023
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v6i7.3262

Abstract

Latar belakang: Corona Virus Disease 2019 (Covid-19) merupakan penyakit menular yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 yang dapat menyebabkan gejala gangguan pernapasan akut seperti demam, batuk dan sesak napas. Dalam penatalaksanaannya, Covid-19 membutuhkan biaya yang besar. Tujuan: Penelitian ini bertujuan untuk mengetahui antibiotik manakah yang paling cost-effective antara azitromisin dan levofloksasin dalam pengobatan Corona Virus Disease-2019 periode 2021 di RSUD Madani Palu. Metode: Desain penelitian ini adalah observasional cross-sectional dengan pengambilan data pasien secara retrospektif (Januari-Desember 2021). Metode penelitian pada penelitian ini adalah purposive sampling. Analisis efektivitas biaya dilakukan dengan menghitung Average Cost Effectiveness Ratio (ACER) dan Incremental Cost Effectiveness Ratio (ICER). Hasil: Jenis kelamin laki-laki sebesar 51% dengan usia 26-45 tahun dibandingkan perempuan sebesar 49%, dan lama rawat inap terbanyak 14 hari. Biaya medis langsung pasien pengguna azitromisin lebih rendah sebesar Rp1.659.698,66 dibandingkan pasien pengguna levofloksasin sebesar Rp1.711.361,17. Nilai ACER antibiotik azitromisin sebesar Rp92.205 dan nilai ACER antibiotik levofloksasin sebesar Rp136.939. Kesimpulan: Dapat disimpulkan bahwa kelompok terapi antibiotik azitromisin lebih cost-effective dibandingkan dengan kelompok terapi antibiotik levofloksasin.
ANALISIS EFEKTIVITAS BIAYA OMEPRAZOLE DAN RANITIDIN PADA PASIEN DISPEPSIA DI INSTALASI RAWAT INAP RSUD UNDATA PALU Hardani, Ririen; Ambianti, Nurul; Safarudin, Rudi; Syafaah , Tri Atainah
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1582

Abstract

The prevalence rate of dyspepsia continues to increase, with cases of recurrence occurring in patients not only adding to the physical and psychological burden of patients, but can also pose an economic burden on both patients and the health system. This study aims to determine the cost of therapy in dyspepsia patients based on the ACER value. This study is a descriptive study, data obtained from medical records and financial data of dyspepsia patients at Undata Hospital, Palu. Data analysis was done descriptively using Microsoft excel and statistically using Kruskal wallis test, Chi-square and independent T-test. The results of the study based on the Kruskal wallis test obtained a p-value of 0.002 which indicates that there is a significant effect of secondary diagnosis on direct medical costs of dyspepsia patients, and the cost effectiveness of therapy based on the ACER value of omeprazole of Rp 35,965 and the ACER value of ranitidine of Rp 28,965. The conclusion of this study is that ranitidine is more cost effective than omeprazole in dyspeptic patients at the inpatient installation of RSUD Undata Palu.
Analisis Faktor yang Mempengaruhi Kepatuhan Pengobatan Antiretroviral pada Pasien HIV/AIDS Ririen Hardani; Amelia Rumi; Afriani Kusumawati; Adelisa Putri; Nurul Ambianti
Journal of Pharmascience Vol. 10 No. 1 (2023): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v10i1.14610

Abstract

Terwujudnya terapi pengobatan yang efektif tergantung dari kepatuhan seseorang meminum obat. Tujuan penelitian ini adalah untuk menetapkan pengaruh faktor pengetahuan, pemberian konseling dan ketersediaan sarana dan fasilitas kesehatan terhadap kepatuhan pengobatan antiretroviral pada pasien HIV/AIDS. Metode pada penelitian ini menggunakan penelitian analitik yang dikerjakan secara cross-sectional dengan menggunakan kuisioner faktor yang mempengaruhi kepatuhan dan kuisioner kepatuhan MARS (Medication Adherence Rating Scale) pada pasien HIV/AIDS yang mengonsumsi obat antiretroviral dengan analisis data menggunakan uji Chi-square dengan nilai signifikan p<0,05. Dari hasil penelitian jumlah sampel yang diperoleh sebanyak 92 pasien, 20 pasien memiliki kepatuhan rendah, 15 pasien memiliki kepatuhan sedang dan 57 pasien memiliki kepatuhan tinggi. Hasil penelitian menunjukkan bahwa pada faktor yang mempengaruhi kepatuhan yaitu pengetahuan dengan nilai signifikan (p=0,001), pemberian konseling dengan nilai signifikan (p=0,000) dan ketersediaan sarana dan fasilitas kesehatan dengan nilai signifikan (p=0,002) memiliki hubungan yang signifikan terhadap kepatuhan. Sehingga dapat disimpulkan bahwa faktor pengetahuan, pemberian konseling dan ketersediaan sarana dan fasilitas kesehatan memiliki pengaruh terhadap kepatuhan pengobatan pasien HIV/AIDS. Kata Kunci: HIV/AIDS, Antiretroviral, Kepatuhan, MARS, Pengobatan  The realization of effective treatment theraphy depends on a person’s adherence to taking medication. The purpose of this study was to determine the effect of knowledge, counseling and availability of health facilities and facilities on antiretroviral treatment adherence in HIV/AIDS patients. The method in this study used an analytic study that was carried out in a cross-sectional manner using a questionnaire on factors that affect adherence and the MARS (Medication Adherence Rating Scale) adherence questionnaire in HIV/AIDS patients taking antiretroviral drugs with data analysis using the Chi-squere test with a significant value. p<0.05. From the results of the study with a total sample of 92 patients, 20 patients had low adherence, 15 patients had moderate adherence and 57 patients had high adherence. The results showed that the factors that influenced adherence, namely knowledge with a significant value (p=0.001), counseling with a significant value (p=0.000) and the availability of health facilities and facilities with a significant value (p=0.002) had a significant relationship. to compliance. So it can be concluded that the factors of knowledge, counseling and availability of health facilities and facilities have an influence on adherence to treatment of HIV/AIDS patients.