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Journal : Jurnal Kedokteran Universitas Palangka Raya

Skrining Fitokimia Tumbuhan Potensi Obat Kanker Kolorektal Begonia Medicinalis Ardi & D.C. Thomas Ardiputra, Muh. Akbar; Musjaya M. Guli; Andi Saifah; Santi; Bambang Sardi; Wafiq Nurfadilah; Mohammad Rivaldi Putra Pratama; Afifah Islamia
Jurnal Kedokteran Universitas Palangka Raya Vol 12 No 2 (2024): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v12i2.13207

Abstract

Cancer is a condition in which cells or tissues undergo abnormal progressive growth. Colorectal cancer is cancer that occurs in the colon to rectum organs of humans. Alternative therapy for colorectal cancer treatment is the use of herbs such as Begonia medicinalis Ardi & D.C. Thomas. This study aimed to screen the bioactive compounds in the Begonia medicinalis Ardi & D.C. Thomas. extract and its potential as a colorectal cancer drug. This research consists of two stages, namely the extraction stage using the maceration method and the screening stage. The results showed that the extract of Begonia medicinalis Ardi & D.C. Thomas. positively contains flavonoids, alkaloids, and saponins. These bioactive compounds have potential activity as preventive and curative agents for colorectal cancer through several mechanisms, including suppressing oxidative stress, inhibiting CDK activity, suppressing intestinal inflammation, and increasing floranormal diversity and probiotic barrier activity in the intestine.
Faktor-Faktor yang Mempengaruhi Peyakit Diabetes Melitus di Kota Palu Musjaya M.; Ayu Dia Agustina; Nur Annisa Safirah; Ardiputra, Muh. Akbar; Sardi, Bambang; Saifah, Andi; Putra, Suwarty Nursahara Usman
Jurnal Kedokteran Universitas Palangka Raya Vol 13 No 1 (2025): Jurnal Kedokteran Universitas Palangka Raya
Publisher : Fakultas Kedokteran, Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/jkupr.v13i1.19586

Abstract

Diabetes mellitus is a metabolic disorder caused by insufficient production of the hormone insulin by the pancreas. This disease can be said to be a chronic disease because it can occur over a long period . This research is about the factors that influence Diabetes Melitus disease in Palu City. This study aims to determine the description of patient visits suffering from Diabetes Melitus at the Central Sulawesi Provincial Laboratory. The sampling technique uses the purpose sampling method, namely purposeful sampling or sampling carried out with subjects based on criteria set by the researcher. The results of this study analyze the factors that influence Diabetes Melitus disease in Palu City. The research result obtained were that there were more women with 288 people and 132 men. Meanwhile, in 2024 from January to march, there will be 90 women and 44 men, the number of patients suffering from diabetes melitus. Namely those aged 46-55 ini 2023 there will be 240 people and ini 2024 there will be 143 people with diabetes melitus agen 40-59 person. The gender factor is that there are more female sufferers of diabetes mellitus compared to male sufferers