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All Journal BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan) Jambura Journal of Health Sciences and Research Journal of Pharmaceutical and Health Research Journal of Fundamental and Applied Pharmaceutical Science Mejuajua Jurnal Pengabdian Masyarakat Tjut Nyak Dhien GEMBIRA (Pengabdian Kepada Masyarakat) Indonesian Journal of Science and Pharmacy
Saputri, Muharni
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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ACTIVITY TEST OF BESTSELLING MOISTURIZERS ON SHOPEE IN TREATING SKIN PROBLEMS Dasopang, Eva Sartika; Siahaan, Desy Natalia; Saputri, Muharni; Irnabila, Salsa
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol. 10 No. 2 (2024): February
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v10i2.10704

Abstract

Shopee is an e-commerce widely used by Indonesians to buy and sell products and can shop safely. Shopee shows that in 2020, moisturizers was the top selling product in the beauty category. The moisturizers sold have different ingredients, come from many brands, and have different price points. The objective of the study is to compare the 3 best-selling moisturizers in the shopee category that are more effective in improving skin problems. This study was a quantitative study using a true experimental design with a posttest only control group design consisting of 4 groups, namely 3 groups using 3 best-selling moisturizer brands based on the shopee category and 1 control group. The sample of this study was selected based on the inclusion criteria consisting of 20 volunteers and the test was conducted for 4 weeks of application on the volunteers' skin by looking at the measured parameters of moisture, pores, blemishes and wrinkles. The results showed that the activity test of moisturizer A had a faster recovery in increasing moisture content (54.8%), shrinking pore size (23.8%), reducing blemishes (19.9%) and wrinkles 28.9%.
CEGAH HIPERTENSI DENGAN MEMANFAATKAN RAMUAN TRADISIONAL: PKM WARGA CEMPAKA BERSAMA MEDAN SELAYANG Saputri, Muharni; Ginting, Ernawaty; Zebua, Nilsya Febrika; Dachi, Kanne; Ningrum, Siti Rahmi; Anggraini, Dea
Jurnal Gembira: Pengabdian Kepada Masyarakat Vol 3 No 06 (2025): DESEMBER 2025
Publisher : Media Inovasi Pendidikan dan Publikasi

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Abstract

Hipertensi merupakan penyakit tidak menular yang kasusnya terus terjadi peningkatan di masyarakat dan menjadi salah satu faktor risiko utama pada penyakit kardiovaskular. Minimnya kesadaran masyarakat terhadap upaya pencegahan hipertensi melalui pola hidup sehat serta pemanfaatan bahan alami menjadi salah satu penyebab tingginya angka kejadian hipertensi. Kegiatan ini bertujuan untuk meningkatkan pengetahuan dan keterampilan warga Bunga Cempaka Gang Cempaka Bersama Kelurahan PB. Selayang II, Kecamatan Medan Selayang, dalam mencegah hipertensi dengan memanfaatkan ramuan tradisional berbahan dasar tanaman obat keluarga (TOGA). Metode kegiatan ini meliputi penyuluhan kesehatan mengenai hipertensi dan faktor risikonya, disertai presentasi cara pembuatan ramuan tradisional penurun tekanan darah seperti daun seledri, daun salam, dan sereh, dengan salah satu metode ekstraksi yaitu infusa. Hasil kegiatan menunjukkan peningkatan pemahaman peserta tentang pentingnya pencegahan hipertensi dan kemampuan mereka dalam meracik ramuan tradisional yang aman dan mudah diaplikasikan. Kegiatan ini diharapkan dapat mendorong kemandirian masyarakat dalam menjaga kesehatan melalui pendekatan alami dan berkelanjutan.
Comparison Between The Suspension and Capsule Preparation from Waste of Avocado Seeds As Antidiarrhea in Induced Mouse Saputri, Muharni; Zebua, Nilsya Febrika; Asih, Fivi Nur; Putri, Ghera Fakhira
Journal of Fundamental and Applied Pharmaceutical Science Vol. 2 No. 2 (2022): February
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v2i2.13504

Abstract

Diarrhea is one type of disease with the most sufferers every year. Thus, it is considered an endemic disease in Indonesia and the potential disease of Extraordinary Events accompanied by mortality. One of the plants that can be used as a traditional medicine for diarrhea is the avocado seed, as it contains tannins, alkaloids, flavonoids, steroids and glycosides, which act as antidiarrheals. This study aims to determine the antidiarrheal effect of avocado seed extract suspension on mice induced by Oleum ricini and the optimum concentration of avocado seed extract suspension and capsules with an antidiarrheal effect in white male mice induced by Oleum ricini. The dosage forms chosen were suspension and capsules. This study used an experimental method with a test sample of the avocado seed. Avocado seed Simplicia was extracted by the percolation method, then an oral suspension and capsule formulation were made from the avocado seed methanol extract. It was evaluated and tested for its effectiveness with mice to cure diarrhea. Normal data were analyzed by One Way ANOVA and Post Hoc Tuckey Method. The results of this study showed that the administration of a suspension of avocado seed methanol extract at a dose of 800 mg/KgBB had the most optimum effect as an antidiarrheal against white male mice with a stool weight of 0.39 grams and a duration of diarrhea for 74 minutes. Furthermore, the administration of avocado seed extract capsules at a dose of 75 mg/KgBB had the most optimum effect as antidiarrheal against white male mice with Loperamide as a positive control. Therefore, it can be concluded that all suspension formulations and capsules of avocado seed methanol extract met the requirements for preparation evaluation. Suspension and avocado seed methanol extract capsules can cure diarrhea in white male mice.
Antimicrobic Activity of IPPU Padang (Ammannia octandra L.f.) Leaves Ethanol Extract against Skin Pathogenic Microbials Saputri, Muharni; Mierza, Vriezka; Putri, Nirwana
Journal of Fundamental and Applied Pharmaceutical Science Vol. 3 No. 1 (2022): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v2i2.13505

Abstract

Ippu Padang plant (Ammannia octandra L.f.) belongs to the family of Lythraceae, a hardy plant that can grow to a height of 50 cm. According to previous research, Ippu Padang leaves contain glycosides, alkaloids, flavonoids and tannins. The presence of alkaloid compounds, flavonoids and tannins is predicted to have potential as an antifungal agent against fungi and antibacterial agent. This research used an experimental method. The steps included collecting plant material, plant identification, processing plants into Simplicia powder, phytochemical screening of Simplicia powder, extracting Simplicia by maceration method using ethanol solvent, antifungal and antibacterial activity test using agar diffusion method and determination of inhibition diameter of leaf ethanol extract. The results of phytochemical screening showed that ippu Padang leaves contained secondary metabolites, namely alkaloids, flavonoids, glycosides, anthraquinone glycosides, tannins, saponins and steroids. The results also revealed that the concentration with the largest inhibitory diameter was 400 mg/ml, namely 12.4 mm against the Candida albicans, 17.46 mm against the Dermacoccus nishinomiyaensis bacteria, 18.53 mm against the Micrococcus luteus bacteria, 19.38 mm against the Pseudomonas aeruginosa bacteria, and 17.71 mm against Staphylococcus epidermidis bacteria. It was concluded that the ethanol extract of ippu Padang leaves could inhibit the growth of the Candida albicans, the bacteria Dermacoccus nishinomiyaensis, Micrococcus luteus, Pseudomonas aeruginosa and Staphylococcus epidermidis.
Co-Authors Amara, Saniatul Anggraini, Dea Anna Juniar Ari Usman, Ari Arianti, Nova Asih, Fivi Nur Dachi, Kanne Dhafi, Muhammad Eva Sartika Dasopang Fanny Rizki Sembiring Febriani, Yessi Fujiko, Muflihah Ginting, Ernawaty Hasanah, Fenny Irnabila, Salsa Julianty, Siti Muliani Kamila, Tazkia Karima, Nurul Linda Margata Mauliza, Indah Mierza, Vriezka Nadia, Syarifah Naswa, Shinta Nerdy Nilsya Febrika Zebua, Nilsya Febrika Ningrum, Siti Rahmi Panjaitan, M Ridho Pangestu Puput, Muharni Saputri Putri, Ghera Fakhira Putri, Nirwana Rajali, Mariany Ramzayani, Astuti Siahaan, Desy Natalia Sitepu, Karolina Sudewi Sudewi Tambunan, Pravil Mistryanto Ulayya, Nadaa Utami, Intan Putri Vivi Sofia Yulia, Rahma Zulkhaira, Zulkhaira