Article Per Year (5 Year)
p-Index From 2020 - 2025
2.096
P-Index
This Author published in this journals
All Journal Pharmaciana: Jurnal Kefarmasian Majalah Obat Tradisional Abditani : Jurnal Pengabdian Masyarakat Jurnal Karinov JUNCTO: Jurnal Ilmiah Hukum Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Jurnal Ilmiah Medicamento COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat Jurnal Locus Penelitian dan Pengabdian Usadha
Putra, I Made Agus Sunadi
Program Studi S1Fakultas Farmasi Universitas Mahasaraswati Denpasar
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Public Health Social Sciences

Published : 21 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 21 Documents
Search

 1   2   3 
Uji Aktivitas Antibakteri Sediaan Gel Hand Sanitizer Ekstrak Etanol Daun Kaktus Pakis Giwang (Euphorbia milli) Terhadap Bakteri Pseudomonas aeruginosa Putra, I Made Agus Sunadi; Putri, Ni Putu Devi Nirmala; Santoso, Puguh
Usadha Vol 4 No 2 (2025): Usadha : Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v4i02.7434

Abstract

The Covid-19 pandemic has heightened public awareness of hand hygiene thus creating a demand for safe and effective natural-based hand sanitizers. This study aimed to determine the antibacterial activity of hand sanitizer gel containing ethanol extract of Euphorbia milli leaves against Pseudomonas aeruginosa. The extract was obtained through maceration of 500 g of powdered leaves in 70% ethanol and formulated into gels with concentrations of 5%, 10%, and 15% using CMC-Na, glycerin, propylene glycol, and methyl paraben as base ingredients. Physical quality tests included organoleptic properties, homogeneity, pH, and spreadability, while antibacterial activity was assessed using the disc diffusion method on Mueller Hinton Agar. All formulations showed brown colour, homogeneous texture, and pH averaging 5.5, meeting standard requirements. The spreadability ranged between 5.0–6.0 cm, indicating good application consistency. Inhibition zone diameters against P. aeruginosa increased with extract concentration: 6.52 ± 0.26 mm (5%), 7.51 ± 0.30 mm (10%), and 8.39 ± 0.35 mm (15%), whereas the positive control (Ciprofloxacin 5 µg) produced 29.92 ± 1.06 mm and the negative control showed 0 mm. Based on inhibition zone classification, all formulations exhibited moderate antibacterial activity. In conclusion, the ethanol extract of Euphorbia milli leaves demonstrates antibacterial potential against Pseudomonas aeruginosa, with effectiveness increasing proportionally to concentration, suggesting its potential as a natural active ingredient for hand sanitizer formulations
Co-Authors Agung Nur Cahyanta Agustini, Ni Putu Dewi Danayasa, I Kadek Debby Juliadi Eko Mugiyanto Erna Cahyaningsih I Gusti Ayu Putri Kartika, I Gusti Ayu I Gusti Ngurah Parikesit Widiatedja Ika Widi Astuti, Ika Widi Ketut Agus Adrianta Ketut Agus Adrianta Megawati, Fitria Meriyani, Herleeyana Nggaba, Ellenoire Rambu Kabeba Hammu Ni Luh Kade Arman Anita Dewi Ni Made Dwi Mara Widyani Nayaka Ni Nyoman Wahyu Udayani Ni Putu Leona Yorita Dewi Ni Putu Udayana Antari Partomuan Simanjuntak Puguh Santoso puguh santoso, puguh Putra Hilmi Prayitno Putri, Ni Putu Devi Nirmala Putu Era Sandhi Kusuma Yuda Riastini, Ni Wayan Rika, Putu SARTIKAWATI, NI KADEK AYU Sasadara, Maria Malida Vernandes Siswa Setyahadi Sri Budiasih, Putu Eka Suwantara, I Putu Tangkas Wardani, I Gusti Agung Ayu Kusuma Yudianti Mendra, Ni Nyoman Yuwono, Moch.