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All Journal Pharmaciana: Jurnal Kefarmasian Majalah Obat Tradisional Abditani : Jurnal Pengabdian Masyarakat Jurnal Karinov JUNCTO: Jurnal Ilmiah Hukum Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Jurnal Ilmiah Medicamento COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat Jurnal Locus Penelitian dan Pengabdian Usadha
Putra, I Made Agus Sunadi
Program Studi S1Fakultas Farmasi Universitas Mahasaraswati Denpasar
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Public Health Social Sciences

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Phytochemical and Pharmacological Activities of Three Colors Fruit (Eugenia Uniflora L) As Antidiabetes and Antibacteries Santoso, Puguh; Udayani, Ni Nyoman Wahyu; Putra, I Made Agus Sunadi; Yuwono, Moch.
Budapest International Research and Critics Institute-Journal (BIRCI-Journal) Vol 4, No 4 (2021): Budapest International Research and Critics Institute November
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v4i4.2861

Abstract

Eugenia uniflora with local name Indonesia   Dewandaru is a plant of the family Myrtaceae. It has green, orange, red, to blackish purple fruits which is widespread in South America, Asia, Africa and Australia. E. uniflora can be used as traditional medicine. The fruits is parts of plants that are widely used in various field nutrition, cosmetic and health, . The active secondary contained in this fuits were applied in anti inflammatory, anti diabetic, adstringent and antioxidant.   Several active compounds found in fruits such a carotene esensial oil and polyphenols have been reported to have some biological activities such as antioxidant antidiabetic and antibacterial. The level maturity of fruits level is related to the contend of secondary metabolites such a fenoloic, carotene esential oils.  The color of E. uniflora fruit is related to the active phytochemical content and antioxidant activity. Three colors of E. uniflora fruit contain beta carotene and phenolic compounds, essential oil, the highest content of phenolic compounds and antioxidants is found in purple fruit This review provides insight into the effort of discovery and development of pharmaceutical agents derived from fruits of Dewandaru (Eugenia uniflora) plants to  make product.
Perlindungan Hukum Bagi Apoteker dalam Melakukan Pelayanan Kefarmasian Secara Elektronik Pasca Pemberlakuan Undang-Undang Kesehatan Putra, I Made Agus Sunadi; Kartika, I Gusti Ayu Putri; Widiatedja, I Gusti Ngurah Parikesit; Astuti, Ika Widi
JUNCTO: Jurnal Ilmiah Hukum Vol 6, No 1 (2024): JUNCTO : Jurnal Ilmiah Hukum JUNI
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/juncto.v6i1.3912

Abstract

Proper legal protection for pharmacists is crucial in ensuring the sustainability of safe, quality, and ethically sound pharmaceutical practices following the enactment of Law Number 17 of 2023 on Health (Health Law). The purpose of this study is to examine the legal protection for pharmacists in conducting electronic pharmaceutical services following Health Law. This research is a normative juridical legal study with conceptual and statutory approach. The results of the study indicate that legal protection for pharmacists in conducting electronic pharmaceutical services enshrined in Health Law is divided into two types of legal protection, namely preventive and repressive legal protection. Preventive legal protection in this health law can be seen through the provisions regarding the rights of pharmacists in conducting pharmaceutical practices, particularly in the context of electronic pharmaceutical practices. Furthermore, regarding repressive legal protection, there are stipulations regarding the dispute resolution process that must be undertaken by the parties involved in medical disputes through both litigation and non-litigation processes.  
Pelatihan Produk Herbal Sediaan Teh Batang Pisang kepada Warga Binaan Lapas Perempuan Kelas IIA Denpasar Dewi, Ni Luh Kade Arman Anita; Megawati, Fitria; Prayitno, Putra Hilmi; Yuda, Putu Era Sandhi Kusuma; Santoso, Puguh; Putra, I Made Agus Sunadi; Nayaka, Ni Made Dwi Mara Widyani; Cahyaningsih, Erna; Udayani, Ni Nyoman Wahyu; Juliadi, Debby; Agustini, Ni Putu Dewi
Jurnal KARINOV Vol 7, No 1 (2024): Januari
Publisher : Institute for Research and Community Service (LP2M), Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/um045v7i1p019

Abstract

Tujuan kegiatan pelatihan ini untuk memberdayakan warga binaan Lapas Perempuan Kelas IIA Denpasar agar memiliki keahlian sebagai bekal berwirausaha untuk meningkatkan produktivitas dan ekonomi selepas masa tahanan, disamping untuk menumbuhkan rasa percaya diri. Kegiatan pelatihan ini juga merupakan upaya diseminasi hasil penelitian tim dosen kepada mitra binaan, yang dalam hal ini ditujukan kepada warga binaan Lapas Perempuan Kelas IIA Denpasar. Metode yang digunakan dalam pelaksanaan kegiatan ini adalah dengan memberikan pengetahuan dan pelatihan keterampilan. Pengetahuan yang diberikan dalam bentuk penyuluhan manfaat farmakologi secara empiris maupun saintifik dari tanaman pisang secara umum maupun mengkhusus pada bagian batang pisang. Pengetahuan tambahan juga diberikan berupa strategi pemasaran produk sediaan herbal. Pelatihan keterampilan diberikan kepada warga binaan dalam bentuk pelatihan mengolah batang pisang menjadi produk sedian teh herbal dari proses awal berupa bahan segar, pembuatan simplisia batang pisang, pencampuran simplisia batang pisang dengan simplisia tambahan (daun mint dan daun stevia) sebagai komposisi teh, sampai dengan pengemasannya. Kegiatan ini dimonitoring dan dievaluasi dengan mengacu kepada keberhasilan warga binaan membuat produk herbal sediaan teh batang pisang, yangmana produk hasil karya warga binaan tersebut dipasarkan di lingkungan internal Kantor Wilayah Kementerian Hukum dan HAM Denpasar. Kata kunci— Pengabdian Kepada Masyarakat, Lapas Perempuan, Teh Herbal Abstract The aim of this training activity is to empower the inmates of the Denpasar Class IIA Women's Prison to have skills to prepare for entrepreneurship to increase productivity and the economy after prison, in addition to growing self-confidence. This training activity is also an effort to disseminate the research results of the lecturer team to partners, which in this case is aimed at residents of the Class IIA Denpasar Women's Prison. The method used in implementing this activity is to provide knowledge and skills training. The knowledge provided is in the form of counseling on the empirical and scientific benefits of pharmacology of banana plants in general and specifically on the banana stem. Additional knowledge is also provided in the form of marketing strategies for herbal preparation products. Skills training is given to inmates in the form of training in processing banana stems into herbal tea products from the initial process in the form of fresh ingredients, making banana stem simplicia, mixing banana stem simplicia with additional simplicia (mint leaves and stevia leaves) as a tea composition, up to packaging. This activity is monitored and evaluated with reference to the success of the inmates in making herbal products made from banana stem tea. Keywords— Community Services, Women’s Prison, Herbal Tea
Formulasi Sediaan Shampo Kombinasi Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb) dan Daun Seledri (Apium graveolens L.) sebagai Antiketombe terhadap Jamur Candida albicans Danayasa, I Kadek; Yudianti Mendra, Ni Nyoman; Sunadi Putra, I Made Agus
Usadha Vol 2 No 3 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i3.7382

Abstract

Dandruff is a scalp condition characterized by an anomaly, often caused by the fungus of Candida albicans. The development of safe and effective anti-dandruff shampoo is imperative. Notably, traditional medicine employs pandan wangi and celery leaves, rich in polyphenols, flavonoids, saponins, tannins and alkaloids as potential anti-dandruff agents. The aims of this study was to formulate and evaluate the antifungal activity of a combination shampoo containing extracts form pandan wangi and celery leaves. Antifungal testing was carried out using the diffusion method using paper discs. Three formulations were prepared FI (without extract), FII (10% pandan leaf extract, 20% celery leaf), FIII (20% pandan leaf extract, 10% celery leaf). Antifungal test was evaluated using the paper disc diffusion method, with 2% ketoconazole shampoo as the positive control. Physical quality test demonstrated favorable attributes for pandan wangi and celery leaf extract shampoo, with FII and FIII exhibiting dark green colors whit distinct odors, while FI remained colorless and odorless. Furthermore, all formulations were in semi-solid dosage forms and met pH requirement for scalps (pH 6,) and produced satisfactory foam yields (6,8-8,9 cm). The antifungal activity test revealed FI as the negative control with a 7 mm and 2% ketoconazole shampoo with a 24 mm inhibition zone, while FII and FIII showed no inhibition zone. The combination of pandan wangi and celery leaf extract in shampoo preparation showed no synergic activity to inhibit the growth of Candida albicans fungus. Further investigations and clinical trials are warranted to validate its effectiveness and safety for practical application.
DIVERSIFIKASI TANAMAN HERBAL MENJADI PRODUK MINUMAN DALAM MENANGGULANGI DEMAM BERDARAH DENGUE Wahyu Udayani, Ni Nyoman; Ketut Agus Adrianta; I Made Agus Sunadi Putra; I Gusti Agung Ayu Kusuma Wardani; Ni Putu Leona Yorita Dewi
Jurnal Abditani Vol. 7 No. 1 (2024): April
Publisher : FAKULTAS PERTANIAN UNIVERSITAS ALKHAIRAAT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31970/abditani.v7i1.282

Abstract

Latar Belakang: Demam Berdarah Dengue merupakan penyakit menular akibat virus Dengue yang disebarkan oleh nyamuk Aedes aegypti dan Aedes abopticus. Demam Berdarah Dengue merupakan masalah yang tengah dihadapi masyarakat Indonesia yang berisiko kematian. Tujuan: Kegiatan Pengabdian ini dapat memberikan edukasi terkait penyakit dan pemanfaatan tanaman herbal sebagai minuman kesehatan sehingga dapat digunakan sebagai pengobatan alternatif. Promosi kesehatan mengenai Demam Berdarah Dengue dan tanaman obat dapat diberikan melalui media buku saku di wilayah Desa Sumerta Kelod sehingga dapat meningkatkan pengetahuan masyarakat. Metode: Pengabdian kepada Masyarakat ini dilaksanakan melaui penyuluhan serta pemberian pretest dan posttest terkait informasi penyakit dan cara penanggulangan melalui pemanfaatan tanaman herbal menjadi minuman kesehatan. Hasil: Pengabdian kepada Masyarakat ini diikuti oleh 30 orang warga Desa Sumerta Kelod, dimana peserta laki-laki sebanyak 8 orang dan peserta perempuan sebanyak 22 orang. Dari data tersebut didapatkan hasil bahwa sebanyak 24 peserta atau sebesar 80% menunjukkan hasil yang positif dilihat dari nilai post-test lebih besar. Kesimpulan: Promosi kesehatan mengenai penyakit Demam Berdarah Dengue dan pemanfaatan tanaman herbal sebagai minuman kesehatan melalui buku saku dapat menghasilkan peningkatan pengetahuan masyarakat dan diharapkan kegiatan seperti ini rutin dilakukan sehingga dapat mencegah terjadinya penyakit Demam Berdarah Dengue di wilayah Desa Sumerta Kelod Kota Denpasar.
Uji Aktivitas Sediaan Hand Sanitizer Ekstrak Etanol Daun Euphorbia milli Terhadap Bakteri Staphylococcus epidermidis Sri Budiasih, Putu Eka; Sunadi Putra, I Made Agus; Santoso, Puguh
Usadha Vol 3 No 2 (2024): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v3i2.7435

Abstract

  Euphorbia milli is a plant that has medicinal properties, one of which is that Euphorbia milli leaves contain peroxidase, saponins, calcium oxalate, peptic substances, and starch. Meanwhile, the sap contains euphorbol, euphol, and cyoartenol. The leaves are widely used as a remedy for boils (furuncle), purulent inflammation of the skin (piodermi), scalds, and burns. Euphorbia milli folia leaves contain saponins, which have potential as antibacterials. This study aims to determine the antibacterial activity of the ethanol extract of the giwang fern cactus leaves on the growth of Staphylococcus epidermidis by making a hand sanitizer gel from the giwang fern cactus leaf extract using three variations of extract concentrations: 5%, 10%, and 15%. The plant extracts were obtained using the maceration method using 70% ethanol with three replications. This research method is laboratory-experimental research. The results showed that the hand sanitizer gel had an inhibitory effect on the growth of the Staphylococcus epidermidis bacteria.
PROFIL PENGGUNAAN ANTIBIOTIKA UNTUK PENGOBATAN ISPA NONPNEUMONIA DI PUSKESMAS KEDIRI II TAHUN 2013 SAMPAI DENGAN 2015 Putra, I Made Agus Sunadi; Wardani, I Gusti Agung Ayu Kusuma
Jurnal Ilmiah Medicamento Vol 3 No 1 (2017): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v3i1.1037

Abstract

ISPA adalah penyakit infeksi akut yang menyerang salah satu bagian atau lebih dari saluran nafas. Infeksi pada saluran pernafasan merupakan penyakit yang umum terjadi di masyarakat, dan penyebarannya sangat mudah dan cepat. Secara umum penyebab dari infeksi saluran nafas adalah berbagai mikroorganisme, namun yang terbanyak akibat infeksi bakteri dan virus. Pengobatannya juga disesuaikan dengan penyebabnya. Penggunaan antibiotika diperlukan apabila penyebab penyakitnya sudah dipastikan bakteri. Kenyataannya dimasyarakat penggunaan antibiotika begitu mudah. Hal ini menimbulkan kekhawatiran terjadinya pengobatan yang tidak rasional dan kemungkinan terjadinya resistensi. Penelitian ini mengumpulkan data yang disajikan sedemikian rupa, untuk menggambarkan penggunaan antibiotika untuk pengobatan ISPA nonpneumonia di Puskesmas Kediri II. Penelitian ini dilakukan dengan metode deskriptif observasional, yaitu penelitian berdasarkan data-data yang sudah ada tanpa melakukan perlakuan terhadap subyek uji. Data diperoleh dari hasil penghitungan resep yang diberikan kepada pasien yang didiagnosa ISPA nonpneumonia, seperti pilek (common cold), sinusitis, faringitis, tonsilitis, laringitis dan ISPA lainnya yang tidak spesifik, yang berobat di Puskesmas Kediri II pada tahun 2013 sampai dengan tahun 2015. Dari penelitian yang dilakukan diperoleh hasil penggunaan antibiotika tahun 2013 sebesar 86,16%, tahun 2014 sebesar 88,61% dan tahun 2015 sebesar 82,73%, dengan Amoxycillin menduduki peringkat tertinggi penggunaan antibiotika yaitu sebesar 92,76%, Cefadroxil 4,19%, Ciprofloxacin 1,34% dan Cotrimoxazole 1,71%.
Pengaruh Pemberian Ekstrak Kunyit Putih (Curcuma zedoaria Rosc.) terhadap Kadar Malondialdehid (MDA) Tikus Putih (Rattus norvegicus) yang Terpapar Asap Rokok Putra, I Made Agus Sunadi; Suwantara, I Putu Tangkas; Sasadara, Maria Malida Vernandes; Udayani, Ni Nyoman Wahyu
Jurnal Ilmiah Medicamento Vol 11 No 1 (2025): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v11i1.10793

Abstract

Cigarette smoke generates free radicals that induce oxidative stress and damage various biomolecules in the body. An increase in malondialdehyde (MDA) levels is a key marker of oxidative stress. The body’s antioxidant mechanisms rely on compounds capable of neutralizing free radicals. White turmeric (Curcuma zedoaria Rosc.) contains antioxidant compounds predicted to prevent oxidative damage, though its in vivo potential remains to be proven. This study aimed to evaluate the effect of white turmeric ethanol extract on MDA levels in male Wistar rats (Rattus novergicus) exposed to cigarette smoke. A post-test only control group design was employed. The rats were divided into five groups: healthy control (P1), smoke-exposed control (P2), extract-treated groups receiving 100 mg/kgBW (P3) and 200 mg/kgBW (P4), and a positive control group receiving vitamin C (P5). Cigarette smoke exposure was administered for 14 days, and blood samples were collected from the orbital vein on day 15. MDA levels were measured using the ELISA method. The mean MDA levels (mmol/ml) for P1 to P5 were 0.118, 0.121, 0.094, 0.059, and 0.089, respectively. ANOVA and post hoc LSD tests (α = 0.05) showed a significant difference between P2 and P4 (p < 0.05), while no significant differences were found between P3, P4, and P5. In conclusion, white turmeric extract at 200 mg/kgBW significantly reduced MDA levels and demonstrated antioxidant activity comparable to that of vitamin C.
Skrining Fitokimiadan Uji Aktivitas Ekstrak Buah Dewandaru (Eugeniauniflora .L) pada Hewan Coba yang Di Induksi Aloksan Santoso, Puguh; Nggaba, Ellenoire Rambu Kabeba Hammu; Udayani, Ni Nyoman Wahyu; Adrianta, Ketut Agus; Putra, I Made Agus Sunadi
Jurnal Locus Penelitian dan Pengabdian Vol. 4 No. 7 (2025): JURNAL LOCUS: Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v4i7.4681

Abstract

Diabetes melitus merupakan gangguan metabolik kronis yang ditandai dengan kadar glukosa darah yang melebihi ambang normal. Tingginya angka penderita diabetes mendorong pengembangan pengobatan alternatif berbasis bahan alam. Salah satu tanaman potensial adalah buah dewandaru (Eugenia uniflora) yang mengandung senyawa bioaktif seperti flavonoid dan asam fenolat yang diketahui memiliki efek hipoglikemik. Penelitian ini bertujuan untuk menguji efektivitas ekstrak etanol buah dewandaru dalam menurunkan kadar glukosa darah pada mencit (Mus musculus) yang diinduksi aloksan. Penelitian ini menggunakan desain eksperimental Pretest-Posttest Only Control Group Design. Ekstrak buah dewandaru diperoleh melalui metode maserasi dan diberikan pada 24 ekor mencit yang dibagi menjadi 4 kelompok (masing-masing 6 ekor). Kelompok 1 (kontrol negatif) hanya menerima aloksan, kelompok 2 (kontrol positif) menerima glibenklamid 5 mg, kelompok 3 menerima ekstrak 100 mg/kgBB, dan kelompok 4 menerima ekstrak 200 mg/kgBB. Kadar glukosa darah diukur pada hari ke-3 (pretest) dan hari ke-14 (posttest) menggunakan glukometer. Data dianalisis dengan uji normalitas Shapiro-Wilk dan uji Paired T-Test menggunakan SPSS 26. Hasil penelitian menunjukkan adanya penurunan kadar glukosa darah yang signifikan (p < 0,05) pada kelompok mencit yang diberi ekstrak 100 mg/kgBB dan 200 mg/kgBB dibandingkan kelompok kontrol. Temuan ini menunjukkan bahwa ekstrak buah dewandaru berpotensi sebagai agen antidiabetes alami, sehingga penelitian lanjutan untuk isolasi senyawa aktif dan uji keamanan jangka panjang sangat dianjurkan.
Formulasi Dan Uji Mutu Fisik Ekstrak Etanol Rimpang Kunyit Putih (Curcuma Zedoaria) Pada Sediaan Tablet Dengan Variasi Bahan Polivinil Pirolidon Dan Starch 1500 Rika, Putu; Juliadi, Debby; Putra, I Made Agus Sunadi
Usadha Vol 2 No 2 (2023): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i2.7363

Abstract

The white turmeric plant (Curcuma zedoaria) is a species from the Zingiberaceae family which is very important in traditional medicine and the medicinal industry. Apart from being used as a food or beverage ingredient, white turmeric is also used as a traditional medicine, such as stomach ache medicine, stomach booster, fever reducer and can treat skin diseases. This study aims to determine the effect of the concentration of polyvinyl pyrrolidone binder and starch 1500 disintegrating agent on the physical properties of tablets and to obtain a white turmeric rhizome ethanol extract tablet formula which has the best physical quality test. The method used in the manufacture of tablets is the wet granulation method, because this method can improve flow properties and increase compressibility. The results of this study on the physical quality testing of FI and FIII tablets have fulfilled the physical quality test requirements for tablets, but FII has not fulfilled the physical quality test requirements for tablet preparations because FII does not meet the disintegration time test requirements, this is influenced by the concentration of polyvinyl pyrrolidone binder (PVP) was higher than Starch 1500 disintegrant. In this study, FIII had the best physical quality test, where FIII was a physical quality test and had the fastest tablet disintegration time, which was 10 minutes. This is influenced by the higher concentration of Starch 1500 disintegrant, which is 8% compared to the polyvinyl pyrrolidone (PVP) binder, which is 5%.
Co-Authors Agung Nur Cahyanta Agustini, Ni Putu Dewi Danayasa, I Kadek Debby Juliadi Eko Mugiyanto Erna Cahyaningsih I Gusti Ayu Putri Kartika, I Gusti Ayu I Gusti Ngurah Parikesit Widiatedja Ika Widi Astuti, Ika Widi Ketut Agus Adrianta Ketut Agus Adrianta Megawati, Fitria Meriyani, Herleeyana Nggaba, Ellenoire Rambu Kabeba Hammu Ni Luh Kade Arman Anita Dewi Ni Made Dwi Mara Widyani Nayaka Ni Nyoman Wahyu Udayani Ni Putu Leona Yorita Dewi Ni Putu Udayana Antari Partomuan Simanjuntak Puguh Santoso puguh santoso, puguh Putra Hilmi Prayitno Putri, Ni Putu Devi Nirmala Putu Era Sandhi Kusuma Yuda Riastini, Ni Wayan Rika, Putu SARTIKAWATI, NI KADEK AYU Sasadara, Maria Malida Vernandes Siswa Setyahadi Sri Budiasih, Putu Eka Suwantara, I Putu Tangkas Wardani, I Gusti Agung Ayu Kusuma Yudianti Mendra, Ni Nyoman Yuwono, Moch.