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Formulation and Activity Testing of Sunscreen Nanoemulsion Cream Derived from 96% Ethanol Extract of Kersen Leaves (Muntingia Calabura L.) Rakhmi Hidayati; Sefi Ela Sari; Yulia Pratiwi; Dessy Erliani Mugita Sari
Indonesian Journal of Pharmacy and Natural Product Vol. 8 No. 02 (2025): Indonesian Journal of Pharmacy and Natural Product
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ijpnp.v8i02.4365

Abstract

Kersen leaves contain secondary metabolite compounds, including flavonoids, phenolics, saponins, and tannins. Nanoemulsion has a colloidal dispersion that has a particle size between 10 and 200 nm. Nanoemulsion was incorporated into a cream base so that when used topically with a relatively small particle size, it can increase the penetration of active substances into the skin. This study aims to determine the physical characteristics and potential of 96% ethanol extract of kersenleaves as a sunscreen based on SPF value. This research is an experimental quantitative research which includes phytochemical screening, making nanoemulsion cream with concentrations of 2%, 4%, and 6%., testing the characteristics of the preparations, testing sunscreen activity in vitro using a UV-Vis spectrophotometer, and statistical data analysis with the SPSS program. The results of phytochemical screening of 96% ethanol extract of kersen leaves (Muntingia calabura L.) showed that the extract positively contained flavonoids, phenolics, tannins, and saponins. The results of the nanoemulsion research particle size test obtained a value of 17.65 nm, the zeta potential test (-18.30), and the transmittance percent test (94.224), which has a clear and transparent visual. Nanemulsion cream formulation with variations in the concentration of 96% ethanol extract nanoemulsion of kersen leaves at F0 (-), F1 (2%), F2 (4%), and F3 (6%) produced has good organoleptic properties and homogeneity, viscosity ranges from 2000 to 50,000 cPs, spreadability ranges from 5 to 7 cm, adhesive power is greater than 1 second, pH preparation is in the range of 4.5 to 6.5, and it is an oil-in-water emulsion type. In the results of the sunscreen activity test, the SPF value obtained at F0 (0.72) has no potential as a sunscreen, F1 (12.15) was in the maximum protection category, F2 (17.34) was in the ultra protection category, and F3 (30.56) was in the ultra protection category. Nanemulsion cream, a 96% ethanol extract of kersenleaves, has potential as a sunscreen. The most optimal nanemulsion cream formula was at an F3 concentration of 6%, with an SPF value of 30.53, entering the ultra protection category.
Bijak Mengelola Obat: Peningkatan Kesadaran Masyarakat tentang Beyond Use Date (BUD) dan Perbedaannya dengan Expired Date (ED) sebagai Upaya Pencegahan Kesalahan Pengobatan Mera Putri Pratitis; Aprillia Puspitasari Tunggadewi; Gunawan Firmansyah; Bagus Riyanto; Yulia Pratiwi; Putriana Ramadhani
Harmoni Sosial : Jurnal Pengabdian dan Solidaritas Masyarakat Vol. 3 No. 1 (2026): Januari: Harmoni Sosial : Jurnal Pengabdian dan Solidaritas Masyarakat
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/harmoni.v3i1.2829

Abstract

Drug storage is not only carried out in health facilities but can also be done independently by the community that consumes drugs, either as an emergency supply or leftover medication from previous use. Drug storage is often done without paying attention to the condition after the packaging is opened or understanding the drug's usage limit/Beyond Use Date (BUD). The community generally only looks at the expiration date/Expired Date (ED) on the drug packaging as a reference for safe drug use, and does not understand the safe usage limit for drugs after the primary packaging is opened. The purpose of this community service is to evaluate the community's knowledge and practices regarding the implementation of BUD/ED, as well as to provide education. This community service was carried out with an educational approach involving 21 people in Rejosari Village. This activity was carried out by distributing questionnaires to the community about the knowledge and practice of BUD/ED daily, then continued with the delivery of education using posters. The results of this activity indicate that the community has good knowledge of ED and BUD, but has not yet implemented ED and BUD in the storage and use of drugs independently.