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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Ilmu Kesehatan J.Abdimas: Community Health Journal of Science and Technology Research for Pharmacy Jurnal DiMas (Jurnal Pengabdian Kepada Masyarakat) Media Farmasi Indonesia Pharmaceutical Sciences and Research (PSR) Journal of Halal Science and Research Jurnal Pengabdian Farmasi dan Sains Jurnal Abdita Naturafarm
Fatmawati, Sofia
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Effect of Extraction Time And GC-MS Analysis of Fresh and Dry Frangipani Flower (Plumeria rubra L.) using Ultrasonic Assisted Extraction Fatmawati, Sofia; Astari, Zhafirah; Bariroh, Tahyatul
Jurnal Ilmu Kesehatan Vol 11 No 1 (2023): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v11i1.3609

Abstract

Frangipani flower (Plumeria rubra) is one of the plants that has a role in perfume and aromatherapy technology which have essential compounds that are the main cause of fragrant smelling flowers. Optimization of extract production needs to be done to obtain a high content of active substances. Ultrasonic assisted extraction is a widely used method for extraction of active compounds in certain products due to shorter operating times. This study aims to determine the effect of variations in extraction time 30,45,60 minutes from fresh and dry frangipani flowers using ultrasonic methods on extract yield values ​​and chemical compositions using the GC-MS method. The results showed that the 60 minutes extraction produced the highest yield values, namely 5.11% for fresh yellow frangipani flower extract and 3.43% for dried yellow frangipani flower. The results of the chemical content study using GC-MS showed that the constituent compounds of fresh yellow frangipani flower essential oil consisted of fatty acids (6.59%), alkanoic acids (4.43%), triterpenoids (1.42%) and floral compound groups. Dry frangipani consists of alkanes (7.47%), alcohol (13.31%), fatty acids (1.00%).
Identification of Prednison and Methyl Prednisolon in Weight-Gain Jamu from Online Marketplace Using TLC-Densitometry Method Fatmawati, Sofia; Siregar, Mirawati; Ananta, Lastri; Adjie, Sundari Kusuma
Jurnal Ilmu Kesehatan Vol 12 No 1 (2024): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

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Abstract

Jamu or traditional medicine is an ingredient or mixture of ingredients derived from plant ingredients, animal ingredients, mineral ingredients, extract preparations (galenic), or a combination of these ingredients which have been used for generations for healing based on experience. Weight-gain jamu is a traditional medicine which is useful for increasing appetite and body weight. The product is widely used today and marketed through online platforms. This study aims to determine the corticosteroids Prednisone and Methyl Prednisolone that are present in weight-gain jamu using the TLC-Densitometry method. This study used 10 samples of weight-gain jamu purchased from the Shopee e-marketplace with inclusive criteria. Silica Gel GF 254 nm was used as the stationary phase. The mobile phases used are chloroform: ethyl acetate (1:9) for prednisone and water-saturated butanol: toluene: ether (5:10:85) for methyl prednisolone. Spiked samples were performed for confirmation of method validation. The results of this research showed that 2 jamu samples contained prednisone at 247 nm wavelength, and no jamu samples were positive for methyl prednisolone. This method could be applied to detect corticosteroids such as prednisone and methyl prednisolone in weight gain herbal medicine.
FORMULASI DAN UJI FAKTOR PELINDUNG SURYA KRIM EKSTRAK ETANOL DAUN KOPI ARABIKA (Coffea arabica L.) Nugrahaeni, Fitria; Fatmawati, Sofia; Nursal, Fith Khaira; Hidayat, Vina Yulia
Media Farmasi: Jurnal Ilmu Farmasi Vol. 18 No. 2: September 2021
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v18i2.19155

Abstract

Salah satu perlindungan kimiawi yang mengurangi efek paparan sinar matahari dengan mengaplikasikan kosmetik tabir surya. Daun kopi mengandung asam fenolik yaitu senyawa antioksidan yang dapat mengeliminasi radikal bebas, berpotensial sebagai sediaan krim tabir surya. Penelitian ini bertujuan memformulasikan ekstrak etanol daun kopi arabika dalam bentuk krim yang memenuhi standar kosmetika tabir surya dan menentukan nilai faktor pelindung surya (FPS) sediaan tersebut. Serbuk daun kopi arabika dimaserasi dengan pelarut etanol. Sediaan krim m/a dibuat 4 formula dengan memvariasikan jumlah ekstrak yang digunakan 0%; 1,5%; 2% dan 2,5% (yaitu F1, F2, F3 & F4). Evaluasi yang dilakukan meliputi pengujian karakteristik fisik krim secara kualitatif dan penentuan nilai faktor pelindung surya. Hasil penelitian evaluasi karakteristik fisik krim menunjukkan semua formula memenuhi persyaratan. Nilai faktor pelindung surya pada konsentrasi 2,5% yaitu F4 didapat hasil tertinggi dengan nilai FPS 5,54 bersifat proteksi sedang. Analisis statistik menunjukkan nilai signifikansi <0,05 sehingga menandakan adanya perbedaan bermakna antar formula terhadap nilai faktor pelindung surya krim.
Pelatihan Pembuatan Sabun Kertas Untuk Meningkatkan Kesadaran Sanitasi Di Pca Bukit Duri, Jakarta Selatan Fatmawati, Sofia; Rindita, Rindita; Bariroh, Tahyatul
Jurnal Dimas Vol 5 No 2 (2023): Jurnal Pengabdian Kepada Masyarakat
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/dimas.v5i2.75

Abstract

Lingkungan yang padat cenderung memiliki sanitasi lingkungan yang kurang baik, dikarenakan terbatasnya fasilitas, kurangnya pengetahuan serta kesadaran masyarakat sekitar terhadap perilaku hidup bersih dan sehat. Sanitasi lingkungan yang kurang baik dapat menyebabkan timbulnya berbagai penyakit, salah satunya adalah penyakit yang disebabkan infeksi mikroorganisme yang hidup di lingkungan dengan sanitasi yang kurang baik, seperti diare, tipes, atau iritasi pada kulit. Tangan merupakan organ yang banyak tercemar dan banyak digunakan untuk melakukan aktivitas sehari-hari seperti untuk makan, mengambil sesuatu, berjabat tangan, dan menyentuh benda-benda yang mudah terkontaminasi mikroorganisme seperti handphone, laptop, atau fasilitas umum lainnya. Mitra yang kami ajak kolaborasi terhadap kegiatan ini adalah Pengurus Cabang Aisyiyah (PCA) Bukit Duri, Jakarta Selatan. PCA ini terletak di lingkungan yang padat penduduk dan terbilang dekat dengan wilayah yang sanitasinya kurang baik karena terdapat kali/saluran air yang berbau, dekat dengan pangkalan angkutan umum yang masih banyak sampah dan berbau. Salah satu kegiatannya adalah menyampaikan tentang pentingnya sanitasi lingkungan yang baik, kesadaran cuci tangan pakai sabun (CTPS), salah satunya menggunakan sabun kertas yang akan kami buat agar lebih menarik, praktis, bisa dibawa kemana-mana, mudah disimpan sehingga tidak segan mencuci tangan dengan sabun. Mitra juga mengatakan belum ada yang melakukan kegiatan yang serupa sebelumnya di wilayah mereka. Kegiatan ini didukung adanya pre-test dan post-test yang menunjukkan hasil post-test lebih tinggi di semua soal yang diberikan dibandingkan dengan hasil pre-test. Kegiatan ini telah dipublikasikan melalui media massa online yaitu pada situs kabar pendidikan dan video pelaksaanaan yang sudah diunggah dalam kanal youtube.
Determination of gelatin from marshmallows using a combination of fourier transform infrared (ATR-FTIR) spectroscopic and chemometrics for halal authentication Fatmawati, Sofia; Hariyanti, Hariyanti; Permanasari, Etin Diah; Chandra, Ady; Firmanto, Johan Dwi; Sari, Retno Lia; Pamungkas, Septiana Tri
Journal of Halal Science and Research Vol. 5 No. 2 (2024): September
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jhsr.v5i2.10537

Abstract

Marshmallow is a foam that contains aerated sugar, which is stabilized with gelatin or egg albumin. In this research, a Fourier Transform Infra-Red (ATR-FTIR) spectroscopy combined with the Chemometrics methods is developed to distinguish the presence of porcine gelatin in marshmallows, which can then be used to identify halal products. This method provides fast and rapid testing of halal products. Marshmallows were made with varying concentrations of bovine and porcine gelatine as the reference. Commercial marshmallows were collected in the online marketplace by purposive sampling. Isolated gelatin was analyzed using the ATR-FTIR spectrophotometer, and data analysis was continued using PCA (Principal Component Analysis). The results showed that bovine gelatin absorbed at a wavenumber of 1638 cm-1, while porcine gelatin produced a sharp absorption at 1697 and 1654 cm-1. The results of PCA analysis show that 100% of bovine gelatin marshmallows (S100) have areas different from marshmallows containing a mixture of porcine gelatin. The PCA results of four samples (A1, A2, A3, and A4) show they are in the same area as 100% bovine gelatin marshmallows (S100). This shows that it is suspected that the four marshmallow samples tested did not contain porcine gelatin. The multivariate regression curve showed that the pattern of linear absorbance changes along with porcine gelatin concentrations with the highest coefficient equation is from wavenumber 1093.97 cm-1.   Keywords: ATR-FTIR, Bovine gelatin, Chemometric, Marshmallow, Porcine gelatin
Co-Authors Adjie, Sundari Kusuma Ananta, Lastri Anisa Amalia Arif Fauzan, Muhammad Astari, Zhafirah Bariroh, Tahyatul Bekti Nugraheni Cahyaningrum, Niken Chandra, Ady Dewi, Elvira Ratna Etin Diah Permanasari Firmanto, Johan Dwi Fith Khaira Nursal Gantini, Sri Nevi Hariyanti Hariyanti Hariyanti Hariyanti Hidayat, Vina Yulia Kartini Kartini Kori Yati Landyyun Rahmawan Sjahid Ni Putu Ermi Hikmawanti Nining Nugrahaeni, Fitria Oktafiani, Erna Pamungkas, Septiana Tri Rahmawan Sjahid, Landyyun Rindita, Rindita Riyanti, Hurip Budi Rusmawati, Lisa Sari, Retno Lia Setyani, Dewi Kurnianingtyas Siregar, Mirawati Siska Siska Tahyatul Bariroh Utami, Nadiyya Maulida Wiyati, Tuti Zainal Arifin