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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Ilmu Kesehatan J.Abdimas: Community Health Journal of Science and Technology Research for Pharmacy Jurnal DiMas (Jurnal Pengabdian Kepada Masyarakat) Media Farmasi Indonesia Pharmaceutical Sciences and Research (PSR) Journal of Halal Science and Research Jurnal Pengabdian Farmasi dan Sains Jurnal Abdita Naturafarm
Fatmawati, Sofia
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Total Phenolic, Total Flavonoid Content and in vitro Sun Protection Factor test of Arabica Coffee Leaves Extract (Coffea arabica L) Fatmawati, Sofia; Sjahid, Landyyun Rahmawan; Utami, Nadiyya Maulida; Kartini, Kartini
Journal of Science and Technology Research for Pharmacy Vol 1 No 2 (2021)
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jstrp.v1i2.51374

Abstract

Background: Arabica coffee leaf (Coffea arabica L.) is a well-known plant by the Indonesian people because it has many benefits apart from being a drink. Coffee leaves are known to have good antioxidant activity. The use of antioxidants in sunscreen preparations can prevent various diseases caused by UV radiation from UV rays’ sunlight. Aim: This study aims to determine the phenol content, the flavonoid content and the value of Sun Protection Factor (SPF) from differences between solvent extracts of arabica coffee leaves (Coffea arabica L.). Method: The extraction method used was maceration with solvents: 70% ethanol, 96% ethanol and methanol. Determination of phenol content was carried out using the Folin ciocalteu method. Determination of flavonoid content was done by the AlCl3 method. SPF value is based on the Mansur equation from absorbance scanning using UV Spectrophotometry. Result: The results obtained were the highest phenol and flavonoid content is in the methanolic extract of arabica coffee namely 62.371 ± 0.47 mgGAE/g and 8.6707 ± 0.04 mgQE/g. In the SPF test, the highest value was obtained from 70% ethanol extract of 5.0593 ± 1.28 at 100 ppm extract concentration with intermediate protection category. Conclusion: Arabica coffee leaves have the potential as an active ingredient in herbal sunscreens
The Effect of Pre-Extraction Preparation on Antioxidant Compounds of Sauropus androgynus (L.) Merr. Leaves Extracts Hikmawanti, Ni Putu Ermi; Fatmawati, Sofia; Arifin, Zainal; Cahyaningrum, Niken; Arif Fauzan, Muhammad
Pharmaceutical Sciences and Research Vol. 8, No. 3
Publisher : UI Scholars Hub

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Abstract

Sauropus androgynus (L.) Merr. (Phyllanthaceae) is a green vegetable. It is rich in natural antioxidant compounds such as phenolics and flavonoids. The pre-extraction preparation can affect the results of extracting compounds from natural materials. This study aims to determine the effect of pre-extraction procedures, including sample form (fresh/dried), drying process (oven-drying/indirect sunlight-drying/air-drying), and particle size (ground/powdered) on total phenolic and flavonoid levels of ethanolic extracts of S. androgynus leaves and their antioxidant activity against DPPH radicals. S. androgynus leaves were extracted using the cold maceration method. The total phenolic and flavonoid contents of the extract were determined by the colorimetric method using a UV-Vis spectrophotometer. Antioxidant activity was measured based on the ability of the extracts to reduce DPPH free radicals. The results showed that the pre-extraction preparation influenced the antioxidant components obtained in S. androgynus leaves. According to sample form, fresh leaves contained a higher phenolics and flavonoids (33.66 mg GAE/g and 11.61 mg QE/g, respectively) than dried leaves. Whereas according to particle size, powdered dried leaves have higher phenolics and flavonoids content (45.12 mg GAE/g and 12.54 mg QE/g, respectively) than ground dried leaves. The leaves drying method that produced the highest phenolic content was oven-drying (47.08 mg GAE/g), while the one with the highest flavonoid content was air-drying (8.87 mg QE/g). All extracts had IC50 values against DPPH radicals around 85.71-93.91 ppm. Pre-extraction preparation in optimum condition makes the extraction process more efficient and effective in obtaining the target compounds with antioxidant activities.
Effect of Extraction Time And GC-MS Analysis of Fresh and Dry Frangipani Flower (Plumeria rubra L.) using Ultrasonic Assisted Extraction Fatmawati, Sofia; Astari, Zhafirah; Bariroh, Tahyatul
Jurnal Ilmu Kesehatan Vol 11 No 1 (2023): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v11i1.3609

Abstract

Frangipani flower (Plumeria rubra) is one of the plants that has a role in perfume and aromatherapy technology which have essential compounds that are the main cause of fragrant smelling flowers. Optimization of extract production needs to be done to obtain a high content of active substances. Ultrasonic assisted extraction is a widely used method for extraction of active compounds in certain products due to shorter operating times. This study aims to determine the effect of variations in extraction time 30,45,60 minutes from fresh and dry frangipani flowers using ultrasonic methods on extract yield values ​​and chemical compositions using the GC-MS method. The results showed that the 60 minutes extraction produced the highest yield values, namely 5.11% for fresh yellow frangipani flower extract and 3.43% for dried yellow frangipani flower. The results of the chemical content study using GC-MS showed that the constituent compounds of fresh yellow frangipani flower essential oil consisted of fatty acids (6.59%), alkanoic acids (4.43%), triterpenoids (1.42%) and floral compound groups. Dry frangipani consists of alkanes (7.47%), alcohol (13.31%), fatty acids (1.00%).
Identification of Prednison and Methyl Prednisolon in Weight-Gain Jamu from Online Marketplace Using TLC-Densitometry Method Fatmawati, Sofia; Siregar, Mirawati; Ananta, Lastri; Adjie, Sundari Kusuma
Jurnal Ilmu Kesehatan Vol 12 No 1 (2024): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

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Abstract

Jamu or traditional medicine is an ingredient or mixture of ingredients derived from plant ingredients, animal ingredients, mineral ingredients, extract preparations (galenic), or a combination of these ingredients which have been used for generations for healing based on experience. Weight-gain jamu is a traditional medicine which is useful for increasing appetite and body weight. The product is widely used today and marketed through online platforms. This study aims to determine the corticosteroids Prednisone and Methyl Prednisolone that are present in weight-gain jamu using the TLC-Densitometry method. This study used 10 samples of weight-gain jamu purchased from the Shopee e-marketplace with inclusive criteria. Silica Gel GF 254 nm was used as the stationary phase. The mobile phases used are chloroform: ethyl acetate (1:9) for prednisone and water-saturated butanol: toluene: ether (5:10:85) for methyl prednisolone. Spiked samples were performed for confirmation of method validation. The results of this research showed that 2 jamu samples contained prednisone at 247 nm wavelength, and no jamu samples were positive for methyl prednisolone. This method could be applied to detect corticosteroids such as prednisone and methyl prednisolone in weight gain herbal medicine.
Peningkatan Pengetahuan Pangan Sehat Aman Serta Kemampuan Pembuatan Bekal Sehat Anak Pada Orang Tua Murid TK Khalifah Jakarta 1: Improving the Knowledge of Safe Healthy Food and The Ability to Make Healthy Meals for Children in Parents of Students at TK Khalifah Jakarta 1 Hikmawanti, Ni Putu Ermi; Fatmawati, Sofia; Wiyati, Tuti
J.Abdimas: Community Health Vol 5 No 1 (2024): J.Abdimas: Community Health - Mei 2024
Publisher : LPPM STIKES Guna Bangsa Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30590/jach.v5n1.662

Abstract

Children are an age group that experiences a period of rapid growth and development during this phase of life, so healthy and safe food intake is needed to support optimal growth and development. Therefore, education about healthy and safe food for parents (guardians) is expected to maintain children's health and build healthy lifestyles for them into adulthood. The aim of implementing this community service program (PPM) is to help increase the knowledge of parents (and guardians) in determining healthy and safe food for children and families. The target of delivering this PPM is to parents (and guardians) of students at TK Khalifah Jakarta 1, located around the Faculty of Pharmacy and Science Campus, UHAMKA, East Jakarta. Implementation of PPM is carried out through the socialization of healthy and safe food materials. Training on making and packaging healthy lunches is also carried out in this activity involving parents (and guardians). Evaluation of the success of this PPM activity is assessed using a questionnaire given before and after the implementation of the activity. Based on statistical analysis, the results showed that there was an increase in knowledge of healthy and safe food and the ability of parents (and guardians) of students to make healthy provisions for children by 72.2% (a=0.05).
EKSTRAKSI BERBANTU ULTRASONIK DAN PENETAPAN KADAR GLUKOMANAN DALAM UMBI PORANG (Amorphophallus oncophyllus Prain ex Hook.f.) Fatmawati, Sofia; Nugraheni, Bekti; Setyani, Dewi Kurnianingtyas
Media Farmasi Indonesia Vol. 11 No. 2 (2016): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.433 KB)

Abstract

ABSTRAK Porang (Amorphophallus oncophyllus Prain ex Hook.f.) merupakan tanaman lokal Indonesia yang termasuk jenis tanaman iles-iles dan dilaporkan mengandung glukomanan cukup tinggi. Glukomanan adalah polisakarida dalam famili mannan dan merupakan polimer dari D-mannosa dan D-glukosa. Ekstraksi glukomanan berbantu gelombang ultrasonik mempunyai keuntungan utama yaitu efisiensi lebih besar dan waktu operasinya lebih singkat. Penelitian ini bertujuan untuk menetapkan kadar glukomanan melalui proses pemurnian glukomanan berbantu ultrasonic menggunakan pelarut isopropanol. Ekstraksi glukomanan berbantu ultrasonik dengan pelarut isopropanol diharapkan dapat menjadi metode pilihan untuk mendapatkan kadar glukomanan yang lebih tinggi dan menjadi metode yang lebih efisien. Studi ini meliputi pembuatan serbuk umbi porang, ekstraksi glukomanan berbantu ultrasonik menggunakan pelarut isopropanol kadar 50% dan 60%, analisis kadar glukomanan dengan metode 3,5-Dinitrosalicylic acid (DNS) dan penentuan gugus fungsional spesifik menggunakan spektrofotometri inframerah (FTIR). Kadar air dalam glukomanan yang diperoleh menggunakan isopropanol 50% dan 60% sebesar 10,58% dan 10,07%. Kadar glukomanan yang didapatkan untuk isopropanol 50% dan 60% adalah 53,17% dan 59,36%. Hasil penentuan gugus fungsional spesifik menggunakan spektrofotometer FTIR menunjukkan puncak-puncak spesifik untuk glukomanan yang dibandingkan dengan referensi.
PENGARUH CARA PENGERINGAN SIMPLISIA TERHADAP KADAR FENOLIK DAN AKTIVITAS TABIR SURYA EKSTRAK ETANOL 70% DAUN CINCAU HIJAU (Cyclea barbata Miers.) Rusmawati, Lisa; Rahmawan Sjahid, Landyyun; Fatmawati, Sofia
Media Farmasi Indonesia Vol. 16 No. 1 (2021): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (563.672 KB) | DOI: 10.53359/mfi.v16i1.171

Abstract

Extract cincau leaves green according to previous studies have the value of the antioxidant IC50 49,45±0,64 µg/mL. According to researchers the phenol formerly produced through a method of drying oven with higher than the drying with sunlight and dried use wind. The research aims to understand the influence of means drying simplisia against phenolic levels total and the activity of a natural sunscreen on extract ethanol 70 % cincau leaves green (Cyclea barbata Miers). Drying simplisia in research is divided into three which is drying with the dry wind, the sun, and an oven. Green leaves cincau simplisia extracted by using the method maceration. Testing the phenolic committed using the folin ciocalteu method. The determination is based on the SPF value Mansur. The results of the value of phenolic or on the program have managed to extract by the difference means drying simplisia dry wind, the rays of the sun and an oven respectively namely 32,7089; 46,2500 and 59,5500 mgGAE / g. The SPF value obtained from each extract with different methods of drying simplisia showed significant differences in various concentration test.
SOSIALISASI BAHAYA BAHAN KIMIA OBAT (BKO) DALAM JAMU DAN PELATIHAN MEMBUAT SEDUHAN HERBAL Hikmawanti, Ni Putu Ermi; Fatmawati, Sofia; Wiyati, Tuti
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 3 No. 1 (2024): Oktober 2024
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2024.v3.i1.17399

Abstract

Jamu is a traditional medicine that is still popular with Indonesian people. Jamu consists of herbs or medicinal plants that are efficacious for preventing disease and maintaining body health. Generally, herbal medicine can be prepared by the community themselves. However, nowadays, herbal medicine has developed a lot and is packaged in the form of products that are ready to be consumed. Unfortunately, several herbal medicine products were found to contain prohibited medicinal chemicals (BKO). The community needs socialization of the dangers of BKO and training in making herbal infusions that are safe, easy and healthy for the body. Women from PKK RT 06 RW 05 Malaka Sari are the targets for this activity. The success achievements of the activities were evaluated with a pre-post-test by filling out a questionnaire. In the future, knowledge regarding the safe selection and method of consuming herbal medicine can be applied in the family to maintain body health and preserve the consumption of herbal medicine as Indonesia's cultural heritage.
Inovasi pengharum ruangan sustainable: pelatihan lilin aromaterapi dan soy wax sachet di Rusunawa Rorotan Siska, Siska; Bariroh, Tahyatul; Fatmawati, Sofia; Rindita, Rindita; Riyanti, Hurip Budi; Yati, Kori
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 5 (2025): September
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i5.30886

Abstract

Abstrak Aromaterapi merupakan terapi pelengkap yang memanfaatkan minyak atsiri dari tanaman beraroma yang mudah menguap dan memberikan efek relaksasi serta manfaat kesehatan. Rusunawa Rorotan memiliki unit hunian terbatas sekitar 30 m², sehingga warga memerlukan kegiatan yang dapat menghilangkan kejenuhan sekaligus meningkatkan keterampilan. Tujuan utama kegiatan ini meliputi peningkatan pemahaman, penerapan gaya hiudp berkelanjutan, pengembangan keterampilan kreatif, penciptaan peluang ekonomi mikro, serta peningkatan kesejahteraan psikologis melalui stimulus olfaktori dan visual. Kegiatan meliputi registrasi, penyampaian materi, praktik pembuatan produk, serta evaluasi melalui pre dan post test. Hasil evaluasi menunjukkan peningkatan signifikan dalam pengetahuan peserta, terlihat dari nilai rata-rata pre-test dan post-test yang berturut-turut mencapai 65,8 dan 82,57, serta respons positif peserta terhadap produk yang mudah dibuat (100%), bentuk produk menarik (74%), dan  memiliki aroma wangi (67%) yang berdampak pada peningkatan mood.  Kesimpulan dari kegiatan ini, secara keseluruhan pelatihan aromaterapi tidak hanya mengurangi kejenuhan di lingkungan padat, tetapi juga mendorong transformasi kearifan lokal menjadi solusi kreatif dna berkelanjutan secara ekonomi bagi warga Rusunawa Rorotan.    Kata kunci: aromaterapi; dekoratif; essential oil; sustainable. Abstract Aromatherapy is a complementary therapy that utilizes essential oils from aromatic plants, which are volatile and provide relaxation and helath benefits. Rusunawa Rorotan has limited living units of approximately and health benefits. Rusunawa Rorotan has limited living units of approximately 30 m², residents face challenges related to psychological well-being and limited opportunities for skill development. This community-based training program aimed to enhance participants’ understanding of sustainable lifestyles, promote the practical application of aromatherapy, foster creative skills, generate microeconomic opportunities, and improve psychological well-being through olfactory and visual stimuli. The program consisted of registration, theoretical sessions, hands-on product-making workshops, and evaluation via pre- and post-tests. Results indicated a significant improvement in participants’ knowledge, with average pre-test and post-test scores rising from 65.8 to 82.57, respectively. Furthermore, participant feedback revealed that 100% found the products easy to make, 74% appreciated the attractive design, and 67% noted pleasant aromas that positively influenced mood. In conclusion, the aromatherapy training effectively alleviated mental fatigue in a densely populated environment and successfully transformed local traditional knowledge into innovative, sustainable, and economically viable solutions for the community of Rusunawa Rorotan. Keywords: aromatherahy; decorative; essential oil; sustainable.
Education on Safe and Halal Cosmetics at SMK Swadaya Global School, East Jakarta: Edukasi Kosmetika Aman dan Halal di SMK Swadaya Global School Jakarta Timur Hariyanti; Gantini, Sri Nevi; Fatmawati, Sofia; Supandi; Nining; Amalia, Anisa; Oktafiani, Erna; Dewi, Elvira Ratna
Jurnal Abdita Naturafarm Vol. 2 No. 2 (2025): J Abdita Naturafarm
Publisher : B-Creta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jan.v2i2.7076

Abstract

The low level of awareness among Muslims regarding the use of safe and halal cosmetics necessitates public awareness education. The purpose of this activity is to educate partners to recognize and choose safe and halal cosmetics, while also becoming agents of change for families or relatives by providing accurate information in choosing safe and halal cosmetics. The educational method is carried out in the form of lectures and simulations of halal cosmetic products. The stages include: pre-test, counseling, simulation, and post-test. Evaluation of the activity is carried out by measuring the level of knowledge and achievement of predetermined objectives. Students demonstrated enthusiasm and active involvement during the activity. The analysis results show an increase in knowledge of the Medium Level from before (40%) and after (60%) the activity. In addition, direct observation also indicates an increase in involvement and deeper understanding among participants. Based on this, it is concluded that education through lectures and simulations introducing safe and halal cosmetics can improve the understanding of students at SMK Swadaya Global School in East Jakarta.
Co-Authors Adjie, Sundari Kusuma Ananta, Lastri Anisa Amalia Arif Fauzan, Muhammad Astari, Zhafirah Bariroh, Tahyatul Bekti Nugraheni Cahyaningrum, Niken Chandra, Ady Dewi, Elvira Ratna Etin Diah Permanasari Firmanto, Johan Dwi Fith Khaira Nursal Gantini, Sri Nevi Hariyanti Hariyanti Hariyanti Hariyanti Hidayat, Vina Yulia Kartini Kartini Kori Yati Landyyun Rahmawan Sjahid Ni Putu Ermi Hikmawanti Nining Nugrahaeni, Fitria Oktafiani, Erna Pamungkas, Septiana Tri Rahmawan Sjahid, Landyyun Rindita, Rindita Riyanti, Hurip Budi Rusmawati, Lisa Sari, Retno Lia Setyani, Dewi Kurnianingtyas Siregar, Mirawati Siska Siska Tahyatul Bariroh Utami, Nadiyya Maulida Wiyati, Tuti Zainal Arifin