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All Journal Dentika Dental Journal Jurnal Teknosains The Indonesian Journal of Dental Research Majalah Kedokteran Gigi Indonesia Jurnal Zeolit Indonesia Dental Journal (Majalah Kedokteran Gigi) Padjadjaran Journal of Dentistry Jurnal Material Kedokteran Gigi DedikasiMU: Journal of Community Service Jurnal Abdi Masyarakat Indonesia JURNAL PENGABDIAN PENDIDIKAN MASYARAKAT (JPPM) Journal Center of Excellent : Health Assistive Technology (CoE)

Dyah Irnawati

Universitas Gadjah Mada

Author-ID : 1157724

Religion Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Efek Samping Lama Aplikasi dari Bleaching Agent Hidrogen Peroksida 40% Terhadap Kekasaran Permukaan Resin Komposit Tipe Nanofill Izfan Yulviansyah; Widjijono Widjijono; Dyah Irnawati
Jurnal Material Kedokteran Gigi Vol 2 No 2 (2013): JMKG Vol 2 No 2 September 2013
Publisher : Ikatan Peminat Ilmu Material dan Alat Kedokteran Gigi (IPAMAGI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (261.726 KB)

Bleaching is a dental treatment chemically on the vital and non vital teeth undergoing discoloration. One technique is in office bleaching. Application of bleaching agent is not only touching the healthy tooth tissue, but also potentially touched restorative nanofill dental composite resins. Materials research is resin composite nanofil (Filtek Z350, 3 m, USA) and the bleaching agent 40% hydrogen peroxide (Opalescense Boost, USA). Disc-shaped sample (diameter 10 mm, thickness 2 mm) as many as 12 samples and divided into 3 groups each sample 4. The samples applied with bleaching agent 40% hydrogen peroxide at room temperatures (25 C) and contact time: 30 minutes, 45 minutes, and 60 minutes. Surface roughness was measured before and after application of bleaching. Surface roughness was measured before and after application of bleaching. Statistical analysis using a one way ANOVA and LSD 0,05. The results showed the average delta composite resin nanofil roughness with time sequential contacts 30, 45 and 60 minutes is 0,040 0,016 µm ± 0,045 µm ± 0.025, and 0.025 ± 0.125 µm. ANOVA test showed that there is a sinificant influence of variation of long application of hydrogen peroxide 40% against a nanofill composite resin surface roughness (p< 0.05). Test LSD indicates there is a significant difference between the delta’s average surface roughness on all groups, except the group of 30 and 45 minutes. Conclusion this research is a variation time contacts of 40% hydrogen peroxide application increases the surface roughness of a composite resin nanofil.

Pengaruh pH Saliva terhadap Kelarutan Ion Aluminium Pada Resin Komposit Nanohybrid Aufia Espressivo; Dyah Irnawati; Purwanto Agustiono
Jurnal Material Kedokteran Gigi Vol 6 No 2 (2017): JMKG Vol 6 No 2 September 2017
Publisher : Ikatan Peminat Ilmu Material dan Alat Kedokteran Gigi (IPAMAGI)

Nanohybrid composite resin is a type of composite resin restorative material containing micro-sized filler particles incorporated with nanoparticles. Composite resin restoration in the oral cavity can release its filler particles, one of them is aluminum ion. The pH of saliva is varied. This research aimed to determine the influence of salivary pH on aluminum ion solubility of nanohybrid composite resin. The materials used were nanohybrid composite resin Tetric Evoceram (Ivoclar Vivadent, Austria) and artificial saliva with pH of 5.6, 6.7, and 8.0. Twelve disc-shaped composite resin samples sized 5 mm in diameter and 2 mm thick were made. Samples were polymerized using light curing unit for 20 seconds. Composite resin samples were divided into three pH groups (n=4) and then each sample was soaked in 10 mL artificial saliva inside of polyethylene bottle. The immersion was done in the incubator for 14 days at 37ºC. The concentration of aluminum ion in artificial saliva solutions subsequently was calculated using AAS. Data were analyzed using One-way ANOVA (a=0,05). The mean concentration of aluminum ion released into saliva with pH 5.6, 6.7, and 8.0 were 0.538 ± 0.996 ppm, 0.431 ± 0.981 ppm, and 0.350 ± 0.071 ppm respectively. The result of One-way ANOVA showed a significant influence of salivary pH variation to the solubility of aluminum ion on nanohybrid composite resin (p<0,05). LSD test showed a significant difference only between saliva pH 5,6 and 8,0. The conclusion of this research was that low salivary pH increased the solubility of aluminum ion on nanohybrid resin composite in saliva.

Perbandingan Kekuatan Fleksural Antara Orientasi Unidirectional dan Bidirectional Fiber Agave Sisalana pada Fiber Reinforced Composite Erfandi Ahmad; Purwanto Agustiono; Dyah Irnawati
Jurnal Material Kedokteran Gigi Vol 3 No 2 (2014): JMKG Vol 3 No 2 September 2014
Publisher : Ikatan Peminat Ilmu Material dan Alat Kedokteran Gigi (IPAMAGI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (524.682 KB)

Fiber reinforced composite (FRC) contains a polimer matrix and fibers. The FRC application as a dental splinting material requires a considerable fleksural strength to withstand the mastication forces. The fiber orientation is one factor influences the mechanical strength of FRC. The aim of study was to compare the fleksural strength between unidirectional and bidirectional orientations of sisal fiber (Agave sisalana) on FRC. The FRC with a flowable composite matrix (Master Flow, Brazil) and sisal fiber (Agave sisalana) (Balittas, Indonesia) were used. The FRC samples (25x2x2mm) were made with unidirectional and bidirectional fibers orientation (n=4). The fleksural strengths were measured using the universal testing machine and the data were analyzed statistically using an independent t-test (a=0,05). The results showed that the average fleksural strength of FRC unidirectional group was 36.56 ± 2.91 MPa and bidirectional group was 24.09 ± 2.08 MPa. The independent t-test showed a significant difference in fleksural strength between unidirectional orientation and bidirectional orientation fiber (p <0.05). This study reveals that the fleksural strength of FRC with unidirectional orientation was greater than the bidirectional orientation of sisal fiber (Agave sisalana).

Pengaruh Konsentrasi Suspensi Cu-zeolit Alam Aktif dalam Akuades terhadap Daya Antimikroba pada Candida albicans Nabilah Aulia Putri; Dyah Irnawati; Purwanto Agustiono
Jurnal Material Kedokteran Gigi Vol 6 No 2 (2017): JMKG Vol 6 No 2 September 2017
Publisher : Ikatan Peminat Ilmu Material dan Alat Kedokteran Gigi (IPAMAGI)

Activated Cu-natural zeolite is an antimicrobial agent (fungicide) combination of copper and carrier agent activated natural zeolite. The aim of this study was to determine the effect of concentration of activated Cunatural zeolitesuspension in aquadest on antimicrobial activity in C albicans. Materials used were natural zeolite (Wonosari), 2 M HCl solution, CuCl2.2H O powder (Merck, Germany), cultured C. albicans, and Sabouraud agar (Merck, Germany). Natural zeolite (50 g) was activated with500 mL 2 M HCl (1 hour/100o C). Activated natural zeolite was reacted with 250 mL 0.2 M CuCl2 (1 hour/100 C). Cu-natural zeolite suspension in aquadest were divided to 3 groups (9 mg/mL, 18 mg/mL, and 36 mg/mL) (n=4). The suspensionwas contacted with C. albicans(120 minutes), diluted, grown on Sabouraud agar, then incubated (48 hours/37oC). The colonies was countedin CFU/mL. Data were analyzed with one way ANOVA test (a = 0,05) and LSD The mean and standard deviation were 36.800 6.453 (9 mg/mL), 31.675 6.445 (18 mg/mL), and 22.375 3.025 (36 mg/mL) (CFU/mL). The result of one way ANOVA test showed that there is influence of the concentration of the suspension to antimicrobial activity in C. albicans (p<0,05). The result of LSD0,05 test showed significant differences between the concentration 36 mg/mL with 9 mg/mL and 18 mg/mL (p<0,05). High concentration of activated Cu-natural zeolite could increase its antimicrobial activity against C. albicans.

Impregnation of various fiber tapes toward mechanical properties of dental fiber-reinforced composites Sunarintyas, Siti; Irnawati, Dyah; Harsini, Harsini; Rinastiti, Margareta; Nuryono, Nuryono
Majalah Kedokteran Gigi Indonesia Vol 9, No 1 (2023): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.80060

Synthetic dental fiber tape for fiber reinforcement (FRC) restoration is relatively costly and its availability is still limited in Indonesia, so natural dental fibers have been used as an alternative material. The aim of this study was to assess the effect of impregnation of various fiber tape toward the flexural strength and hardness of FRC. The materials used were natural Bombyx mori silk fibers (Indonesia), dental polyethylene tape (Construct Kerr, USA), dental Quartz tape (Quartz Splint UD, France), dental E-glass tape (Everstick TM, GC, Japan), silane coupling agent (Ultradent, Jordan), and composite resin (Denfil-Flow, USA). Five groups of samples consisted of FRC with various fiber tapes were prepared: unidirectional-silk, braided-silk, quartz, polyethylene, and E-glass. The five groups of FRC were tested to determine the flexural strength and hardness. The results were analyzed by one-way ANOVA, followed by LSD test. The results showed that the highest flexural strength was in the quartz group (496.84 ± 109.14 MPa), while the lowest was in the braided-silk group (139.39 ± 4.30 MPa). The highest hardness property was in the unidirectional-silk group (141.29 ± 25.17 VHN), while the lowest was in the braided-silk group (139.39 ± 4.30 VHN). The ANOVA showed that various fiber tapes significantly influenced the flexural strength and hardness of FRC (p < 0.05). The LSD showed that the unidirectional-silk, braided-silk, and polyethylene groups demonstrated no significant difference. The LSD for hardness showed that the unidirectional-silk group had a significant difference with the other groups (p < 0.05). It can be concluded that various fiber tapes influenced the flexural strength and hardness of FRC. Natural silk fibers showed comparable flexural strength and hardness with the other fiber tapes.

Effect of zinc oxide nanoparticle concentration coated on acrylic resin upon surface roughness and abrasion resistance Yoga, I Gede Krisna Merta; Harsini, Harsini; Sunarintyas, Siti; Handajani, Juni; Nuryono, Nuryono; Irnawati, Dyah
Majalah Kedokteran Gigi Indonesia Vol 10, No 1 (2024): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.92000

Acrylic resin is the material most often used as a base for dentures; however, acrylic resin has shortcomings in its biological properties as it does not have antimicrobial properties. ZnO is added to acrylic resin because of its antimicrobial properties. The aim of this research is to determine the effect of the concentration of ZnO nanoparticles as a heat polymerization acrylic resin coating on the coating’s resistance to abrasion. A total of 24 acrylic resin samples were made, each measuring 13 x 13 x 2 mm. The acrylic resin was coated with 3-(trimethoxysilyl)propyl methacrylate), then with ZnO nanoparticles with varying concentrations of 2.5%, 5%, and 7.5% in ethanol. ZnO nanoparticle coating was applied using the dip coating method. Subsequently, the samples were subjected to an initial roughness test, abrasion test, and final roughness test. The data obtained were analyzed using one-way ANOVA and LSD(0.05). The results showed that the mean change in roughness (μm) and standard deviation for groups I to IV were 0.11 ± 0.13, 0.08 ± 0.33, 0.1 ± 0.12, and 0.19 ± 0.15, respectively. The results of the one-way ANOVA test showed that there was no significant difference in the roughness after the abrasion test (p > 0.05). Thus, zinc oxide nanoparticles can reduce surface roughness and are resistant to surface abrasion.

Pengabdian Masyarakat tentang Peningkatan Kesehatan Gigi dan Mulut di Pondok Pesantren Ta'lim Sabilu Taubah Kecamatan Srengat Kabupaten Blitar Lukis, Prima Agusti; Setiawan, Fery; Prakosa, Basma Rosandi; Khafid, Mohammad; Handajani, Juni; Hanindriyo, Lisdrianto; Irnawati, Dyah; Susilowati, Heni; Sunarintyas, Siti
Jurnal Abdi Masyarakat Indonesia Vol 5 No 2 (2025): JAMSI - Maret 2025
Publisher : CV Firmos

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54082/jamsi.1825

Persepsi kebersihan gigi dan oral memiliki dampak besar pada harapan hidup di seluruh dunia. Namun, di negara-negara dengan pendapatan sedang, beban meningkat secara tidak proporsional. Prob-lema kesehatan gigi dan mulut di Indonesia merupakan problem yang mempengaruhi populasi sebanyak 57.6%. Studi ini adalah studi semi-eksperimental yang dilakukan pada 16 Desember 2024 di Ta’lim Sa-bilu Taubah Gas Iqdam, Blitar, Jawa Timur, Indonesia. Metode sosialisasi dilakukan secara offline (tatap muka) menggunakan campuran media presentasi (power point) dan booklet. Peserta sosialisasi dibagi menjadi dua bagian: pra-sosialisasi (pre-test) dan pasca-sosialisasi (post-test). Peserta sosialisasi diberi-kan pertanyaan untuk menilai pengetahuan dan persepsi peserta mengenai kesehatan gigi dan mulut pada saat sebelum dan sesudah sosialisasi. Pengetahuan peserta diklasifikasikan sebagai cukup, sedang, dan rendah dalam memahami kebersihan gigi dan mulut sebelum dan setelah sosialisasi. Skor rata-rata untuk peserta sebelum sosialisasi adalah 26,45, dan setelah sosialisasi menjadi 83,23. Hasil tersebut ber-beda bermakna dengan nilai-p 0.000 menggunakan uji statistik wilcoxon. Data ini menunjukkan bahwa terdapat peran positif dari dokter gigi dalam meningkatkan kesehatan gigi dan mulut pasien sehingga dokter gigi dapat berperan aktif untuk mendorong pasien lebih memperhatikan kesadaran kesehatan gigi dan mulut terutama bagi pondok pesantren Ta’lim Sabilu Taubah di Kabupaten Blitar.

PROMOSI KESEHATAN DENTAL: UPAYA MENINGKATKAN KEBERSIHAN MULUT MELALUI BUAH-BUAHAN LOKAL PADA MASYARAKAT DESA SRENGAT, BLITAR Moh. Khafid; Fery Setiawan; Juni Handajani; Lisdrianto Hanindriyo; Dyah Irnawati
DedikasiMU : Journal of Community Service Vol. 7 No. 2 (2025): DedikasiMU Juni
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/dedikasimu.v7i2.9889

Kesadaran akan kesehatan gigi dan mulut mempunyai dampak yang signifikan terhadap peningkatan angka harapan hidup di seluruh dunia. Bebannya semakin tidak seimbang di negara-negara berpendapatan rendah dan menengah. Menurut Riskesdas 2018, permasalahan kesehatan gigi dan mulut di Indonesia sebesar 57,6%. Prevalensi karies di Provinsi Jawa Timur meningkat sebesar 54,22% pada tahun 2018. Peningkatan ini tidak terlepas dari konsumsi makanan instan dan minuman berenergi yang dapat menyebabkan suasana asam pada rongga mulut sehingga menyebabkan prevalensi risiko karies. Promosi kesehatan gigi ini dilakukan di Jemaah Ta’lim Sabilu Taubah Gus Iqdam, Blitar, Jawa Timur, Indonesia, pada tanggal 16 Desember 2024 untuk meningkatkan kebersihan mulut mereka melalui penggunaan buah-buahan lokal yang terdapat di Srengat, Blitar. Cara sosialisasi ini ditujukan kepada masyarakat yang menggunakan modus offline (langsung). Buah-buahan lokal yang banyak ditemui di Srengat Blitar adalah nanas. Buah nanas diklaim sebagai buah yang dapat meningkatkan self-cleansing. Disclosing agent akan membuat masyarakat mengetahui kategori kebersihan mulut mereka karena disclosing agent ini berfungsi sebagai penanda pada gigi mereka. Setelah mengetahui tentang kebersihan mulut, maka mereka dapat meningkatkan kebersihan mulut dengan mengonsumsi nanas sebagai bahan pembersih diri. Sosialisasi kesehatan gigi ini akan meningkatkan kebersihan mulut sehingga dapat menurunkan angka kejadian karies.

Effect of corncob powder concentration on properties of inlay waxes Irnawati, Dyah; Harsini; Widjijono; Siswomihardjo, Widowati; Sunarintyas, Siti; Yasnawi, Mohammad Imanuddin; Verani, Dhea Maurilla
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 3 (2025): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i3.p242-248

Background: Corncob powder is a promising filler that needs to be assessed when it is incorporated into inlay waxes to modified its properties. Purpose: This study aims to investigate the effect of different concentrations of corncob powder filler on physical and mechanical properties of inlay waxes. Methods: Five groups of inlay waxes were prepared from paraffin, corncob powder, carnauba wax, and beeswax in varying proportions (w/w%), namely, group I (70:0:25:5), II (65:5:25:5), III (60:10:25: 5), IV (55:15:25:5), and V (50:20:25:5). The wax mixture was heated at 80°C, filtered, added with corncob powder, and stirred until homogeneous then poured into mold for melting point, residue on ignition, flow, hardness, and trimming samples. They were based on ANSI/ADA specification no.122 and ASTM D 1321. The data were analyzed through one-way ANOVA, post-hoc LSD, and Tamhane tests (p = 0.05), except trimming test data. Results: One-way ANOVA revealed that the concentration of corncob filler influenced all inlay waxes properties (p<0.05). LSD and Tamhane post-hoc test, showed significant different among mostly between groups of tests. Addition corncob powder increased the melting point, hardness, and residue of inlay waxes but decreased the flow of inlay waxes. Addition corncob did not influence the trimming property of inlay waxes. Conclusion: The concentration of corncob filler added in inlay wax compositions influenced the melting point, flow, hardness and residue properties but did not influence trimming properties. Inlay wax containing 10% corncob filler potential as a local inlay wax, but further research should be done to overcome the residue on ignition property that higher than standards.

Antisense oligonucleotide p45Skp-2 suppresses migratory chemotactic and metastasis of oral malignant Burkitt’s lymphoma cell through down-regulation of MTA-1 and induction of E-cadherin mechanism Supriatno, Supriatno; Irnawati, Dyah; Medawati, Ana
Padjadjaran Journal of Dentistry Vol 32, No 3 (2020): November 2020
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol32no3.21756

Introduction: Burkitt’s lymphoma is a high-grade B-cell neoplasm and one of the most aggressive malignancies of lymphoid origins which found mainly in the paediatric population. The treatment options of this tumour are still limited. However, a new strategy for refractory tumour, phosphorothioate oligonucleotide antisense technique has watched with keen interest. This study was aimed to examine the effect of antisense p45Skp-2 (Skp-2 AS) suppressed migratory chemotactic and metastasis of oral malignant Burkitt’s lymphoma (Raji) cell through down-regulation of MTA-1 and E-cadherin. Methods: True experiment laboratory with post-test control group design was confirmed in this study. The efficiency of Skp-2 AS in the suppression of cell chemotactic migration was examined by Boyden chamber assay. To evaluate the inhibition of cell metastasis was conducted by decreasing MTA-1 expression protein. The expressions of MTA-1, E-cadherin and α-tubulin protein were investigated by Western blot analysis. Results: The results revealed that the number of chemotactic migration of Skp-2 AS treated Raji cell was significantly decreased when compared with that of sense p45Skp-2 (Skp-2 S) and scrambled control (SC) cells (P<0.05) followed by decreased expressions of MTA-1 protein and overexpression of E-cadherin. Interestingly, the expression of α-tubulin protein as an internal control was approximately similar in each transfectant cells. Conclusion: p45Skp-2 have an antitumor activity via suppression of migratory chemotactic activity and metastasis on oral Burkitt’s lymphoma cells through down-regulation of MTA-1 and induction of E-cadherin proteins targeting this molecule could represent a promising new therapeutic approach for this type of cancer.

Co-Authors Alizatul Khairani Hasan Ana Medawati, Ana Aufia Espressivo Dea Cahyani, Yessica Endi Hanifah Wardhani Endi Hanifah Wardhani, Endi Hanifah Erfandi Ahmad Fery Setiawan Fery Setiawan Fitri Isnaini Fitri Isniani Harsini Harsini, Harsini Heni Susilowati Izfan Yulviansyah Jukka Pekka Matinlinna Juni Handajani Karna Wijaya Lisdrianto Hanindriyo Lisdrianto Hanindriyo Lukis, Prima Agusti Margareta Rinastiti Mochammad Imron Awalludin Moh. Khafid Mohammad Khafid Nabilah Aulia Putri Nuryono Nuryono Paramarta, Sagita Pradnya Prakosa, Basma Rosandi Purwanto Agustiono Purwanto Agustiono Purwanto Agustiono Purwanto Agustiono, Purwanto Siti Sunarintyas Supriatno Verani, Dhea Maurilla W. Widjijono Widowati Siswomihardjo Widowati Siswomiharjo Widya Asmara Yasnawi, Mohammad Imanuddin Yoga, I Gede Krisna Merta

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