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Perbandingan Efektivitas Ekstrak Daunn Kirinyuh (Chromolaena odorata) dan Povidone Iodine 10% Terhadap Angiogenesis Pada Luka Insisi Kulit Tikus Putih (Sprague dawley) Panjaitan, Yolanda Indah Wirijayanti; Telussa, Arley Sadra; Sihotang, Jojor Sadra
Cendana Medical Journal Vol 11 No 2 (2023): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v11i2.13938

Abstract

Abstract Background: Wound is an injury or damage in the body tissue. The use of herb as traditional medicine for the treatment of wound was still commonly found. The siam weed leaf (Chromolaena odorata) is one of the herbs found in Indonesia which was still used as a traditional medicine for wound recovery. Siam weed leaf (Chromolaena odorata) has an effect in wound recovery and may increase angiogenesis. Povidone iodine 10% was currently the standard treatment for wound and has an antiseptic effect. Method: This is an experimental study. The mice was divided into 4 groups which were control group (P1) which was treated with Povidone iodine 10%, treatment group I (P2) which was treated with siam weed leaf (Chromolaena odorata) extract 10%, treatment group II (P3) which was treated with siam weed leaf (Chromolaena odorata) extract 15% and treatment group III (P4) which was treated with siam weed leaf (Chromolaena odorata) extract 20%. Angiogenesis was examined under microscope for angiogenesis count. Data was analyzed using the Kruskall Wallis test. Result: The result of this study showed the p value of p=0.294 (>0.05). Conclusion: Siam weed (Chromolaena odorata) leaf extract and Povidone iodine did not show any significant difference in effectivity to the angiogenesis in incision wound in Sprague dawley white mice.
Hubungan Tingkat Pengetahuan Kesehatan Reproduksi Dengan Perilaku Seksual Remaja Pada Siswa–Siswi Kelas XII SMA Negeri 2 Kefamenanu Ni Wayan Ruci Radha Ningsih; Gottfrieda Patiencia Taeng-Ob Adang; Halena Meldy Asa; Arley Sadra Telussa
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

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Abstract

Remaja merupakan kelompok usia transisi menuju dewasa yang rentan terhadap perilaku seksual berisiko apabila tidak memiliki pengetahuan kesehatan reproduksi yang memadai. Kurangnya pemahaman mengenai anatomi reproduksi, kontrasepsi, dan Infeksi Menular Seksual (IMS) dapat memengaruhi perilaku seksual remaja. SMA Negeri 2 Kefamenanu menjadi lokasi penelitian untuk menilai hubungan antara pengetahuan kesehatan reproduksi dan perilaku seksual remaja. Penelitian ini bertujuan untuk mengetahui hubungan antara tingkat pengetahuan kesehatan reproduksi dengan perilaku seksual remaja pada siswa- siswi kelas XII SMA Negeri 2 Kefamenanu. Penelitian ini menggunakan desain analitik dengan pendekatan cross- sectional. Sampel terdiri dari 257 siswa-siswi kelas XII yang memenuhi kriteria inklusi. Data dikumpulkan menggunakan kuesioner terstruktur dan dianalisis secara univariat dan bivariat menggunakan uji Chi-Square dengan tingkat signifikansi 0,05. Penelitian menunjukkan bahwa sebagian besar responden memiliki pengetahuan kesehatan reproduksi tinggi (89,9%). Sebanyak 84,4% responden memiliki perilaku seksual tidak berisiko. Hasil uji Chi-Square menunjukkan nilai p < 0,001, yang berarti terdapat hubungan yang signifikan antara tingkat pengetahuan kesehatan reproduksi dengan perilaku seksual remaja. penelitian ini menunjukkan bahwa terdapat hubungan yang signifikan antara pengetahuan kesehatan reproduksi dengan perilaku seksual remaja. Semakin tinggi pengetahuan kesehatan reproduksi, semakin rendah kecenderungan remaja melakukan perilaku seksual berisiko. Oleh karena itu, edukasi kesehatan reproduksi perlu ditingkatkan secara berkelanjutan.
ONE-STAGE MODIFIED BIPEDICLED SCROTAL FLAP IN PENILE SCLEROSING LIPOGRANULOMA SURGICAL RECONSTRUCTION: A CASE SERIES Telussa, Arley Sadra; Datusanantyo, Robertus Arian; Kale, Letitia Bellavesta; Djunaedi, Angela
Indonesian Journal of Urology Vol 33 No 2 (2026)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v33i2.968

Abstract

Introduction: Sclerosing lipogranuloma is commonly encountered by urologists and plastic surgeons. Despite potential permanent damage, increasing penile size by injecting unusual substances, usually oil-based, becomes a trend in society. The immediate result, practicality, and affordability of the procedure caused penile shaft deformity, pain, and difficulties in sexual activity. Objective: This study aims to report three cases of modified scrotal flap reconstruction techniques to reconstruct heavily deformed penile shafts with satisfying results. Case(s) Presentation: Three males presented with painful enlarged and deformed penile shaft following a penile enlargement procedure by injection of unusual substances done by non-medical practitioners. Following penile sclerosing lipogranuloma diagnosis, lipogranuloma excision and one-stage modified bipedicle scrotal flap were conducted for all patients. Discussion: A reconstructive procedure is needed to eliminate pain and restore sexual functions. Among available surgical reconstruction techniques, the bipedicled scrotal flap was more suitable in most limited healthcare setting for its less technical complexity, fewer complications, better aesthetic outcomes, and better sexual functions. All cases were reconstructed in a one-stage procedure, they were cost-efficient without losing their features. Conclusion: The one-stage modified bipedicled scrotal flap technique is a beneficial technique for penile reconstruction caused by sclerosing lipogranuloma, especially in health centers where patients reside in distant places. Keywords: Sclerosing lipogranuloma, scrotal flap, reconstruction techniques.
Pengaruh Cool-Down Stretching terhadap Intensitas Delayed Onset Muscle Soreness pada Otot Biceps Brachii Setelah Latihan Beban Fearen Finery Ludji; Su Djie To Rante; Kartini Lidia; Arley Sadra Telussa
Journal of Comprehensive Science Vol. 5 No. 2 (2026): Journal of Comprehensive Science
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jcs.v5i2.4007

Abstract

Latihan beban merupakan program latihan menggunakan beban dengan banyak potensi untuk kesehatan tubuh. Delayed Onset Muscle Soreness (DOMS) menjadi salah satu alasan menurunnya motivasi untuk melanjutkan program latihan, sehingga manfaatnya tidak optimal. Cool-down stretching merupakan salah satu modalitas untuk mengurangi risiko terjadinya DOMS setelah berolahraga. Namun, banyak penelitian memiliki hasil yang bertolak belakang mengenai efektivitas cool-down stretching terhadap DOMS. Mengetahui efektivitas cool-down stretching terhadap intensitas DOMS pada otot biceps brachii setelah latihan beban. Menggunakan desain penelitian True Experimental dengan pedekatan Posttest-Only Control Group Design. Peneliti menginduksi DOMS menggunakan latihan beban pada otot biceps brachii, lalu kelompok intervensi diberikan perlakuan cool-down stretching. Posttest dilakukan untuk mengukur intensitas DOMS menggunakan 100mm Visual Analog Scale. Teknik pengambilan sampel dengan simple random sampling dan jumlah sampel masing-masing kelompok sebanyak 16 orang. Uji bivariat menggunakan Independent T-Test dan Mann Whitney U Test, dan uji multivariat dengan Two Way Anova. Rerata intensitas DOMS pada kelompok kontrol dan intervensi secara berururtan, untuk 24 jam sebesar 64,56 dan 41,50, untuk 48 jam sebesar 43,38 dan 31,88, serta untuk 72 jam sebesar 24,94 dan 34,38. Hasil bivariat menunjukkan nilai p=0,007 (p<0,05) untuk 24 jam, p=0,116 (p>0,05) untuk 48 jam, dan p=0,806 (p>0,05) untuk 72 jam. Cool-down stretching efektif dalam menurunkan intensitas DOMS setelah 24 jam, tetapi tidak efektif setelah 48 dan 72 jam.
The Relationship Between Duration of Hemodialysis and Level of Depression Among Hemodialysis Patients in Kupang City Suriana Desty Maltus; Teguh Dwi Nugroho; Audrey Gracelia Riwu; Arley Sadra Telussa
Jurnal Kesehatan dan Kedokteran Vol. 5 No. 1 (2026): Februari: Jurnal Kesehatan dan Kedokteran
Publisher : Asosiasi Dosen Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56127/jukeke.v5i1.590

Abstract

Hemodialysis is a long-term renal replacement therapy that can affect patients’ daily functioning and psychological well-being. Depression is common in this population and may reduce quality of life and treatment adherence. However, evidence on whether hemodialysis duration is associated with depression remains inconsistent, and local multi-center data from Kupang City are limited. Objective: To analyze the relationship between duration of hemodialysis and depression level among hemodialysis patients in Kupang City. Methods: A quantitative cross-sectional study was conducted in July–August 2025 at three hemodialysis centers in Kupang City (RSUD W.Z. Johanes, RS Siloam, and RSUP Ben Mboi). Using purposive sampling, 163 respondents were recruited from a population of 365 routine hemodialysis patients. Depression was assessed using the Beck Depression Inventory-II (BDI-II). Hemodialysis duration was obtained from medical records and categorized as <12 months, 12–24 months, and >24 months. Data were analyzed descriptively and tested using the Chi-square test. Findings: Most respondents were not depressed (60.7%), while 39.3% had mild to severe depression. The largest proportion had undergone hemodialysis for >24 months (35.6%). There was no statistically significant association between hemodialysis duration and depression level (p = 0.434). Implications: Depression among hemodialysis patients appears to be influenced by factors beyond treatment duration, supporting the need for routine depression screening and psychosocial support integrated into hemodialysis care. Originality: This multi-center study provides local evidence from three hospitals in Kupang City using a standardized instrument (BDI-II), helping clarify inconsistent prior findings and reinforcing a multifactorial view of depression in hemodialysis patients.
Percutaneous Nephrolithotomy For Staghorn Stones: A Minimally Invasive Approach In A Region With Elevated Kidney Stone Risk Dewa Gede Agung Sasmara Putera; Zaky Ariandy; Arley Sadra Telussa
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.22406

Abstract

A 41-year-old male with a 2-month history of left-sided abdominal pain and renal stones was treated at Prof. W. Z. Johannes Hospital, East Nusa Tenggara, Indonesia. The patients’ primary drinking water sources were rivers and refillable bottles, which elevated the risk of kidney stones. Plain radiography and MSCT imaging revealed a 5 cm x 3.5 cm staghorn stone in the left kidney. Percutaneous nephrolithotomy (PCNL) was performed in the supine position using the C-arm. A nephroscope was inserted through a small incision to visualize and extract the stone. Post-extraction, C-arm imaging assessed the kidney, and a nephrostomy tube was placed for drainage. Staghorn stones are large, branched stones that occupy much of the renal pelvis or calyces. The European Association of Urology (EAU) recommends PCNL as the first-line treatment for staghorn stones due to its high efficacy and low morbidity. PCNL, a minimally invasive approach, offers high stone-free rates, up to 95%, making it effective for stones over 20 mm. The patient's successful outcome highlights the efficacy of PCNL in managing staghorn stones, especially in areas with a high risk of kidney stones due to poor water quality. Early diagnosis and treatment avert severe complications such as recurrent infections and urosepsis.
In Vitro Antibacterial Activity Test of Ethanolic Extract of Kersen (Muntingia calabura L.) Leaves Against the Growth of Escherichia coli Abigail Eugelia Veterine Angsar; Rr Listyawati Nurina; Gottfrieda Patiencia Taeng-Ob Adang; Arley Sadra Telussa
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.27195

Abstract

Background: Diarrhea is a global health problem that causes millions of deaths every year. Treating diarrhea often involves the use of antibiotics, but antibiotic resistance is a serious problem. Cherry plants (Muntingia calabura L.) has been used traditionally to treatt infections . This research can provide new insights regarding the potential of using cherry plants as an alternative for treating bacterial infections without relying only on antibiotics. Objective: To determine the antibacterial activity of ethanol extracts from the cherry leaves (Muntingia calabura L.) against the Escherichia coli growth. Methods: This research is using a true experimental method with a post-test only control group design. The bacteria used is Escherichia coli with 8 treatment groups, the positive control group using ciprofloxacin, the negative control group using sterile aquadest, and six concentrations of cherry leaf extract treatment groups. The data was analyse with One Way Anova test. Results and Discussion: Inhibition zones produced at the concentrations of 100%, 50%, 25%, 12.5%, 6.25%, 3.125% measuring 15.39 mm ; 14.02 mm; 11.82 mm; 10.82 mm; 9.64 mm; 8.32 mm , indicating strong to moderate antibacterial effects. Conclusion: Ethanol extracts of cherry leaves (Muntingia calabura L.) exhibit antibacterial activity against Escherichia coli in vitro. Keywords: Ethanol Extracts from Cherry Leaves, Antibacterial Activity, Escherichia coli, in vitro.