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All Journal Biosfer: Jurnal Tadris Biologi Journal of Islamic Medicine JURNAL PENDIDIKAN TAMBUSAI Amerta Nutrition Care : Jurnal Ilmiah Ilmu Kesehatan 2-TRIK: TUNAS-TUNAS RISET KESEHATAN Nutrix Journal Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Kesehatan: Jurnal Ilmu- Ilmu Keperawatan, Kebidanan, Farmasi dan Analis Kesehatan Aksara: Jurnal Ilmiah Pendidikan Bahasa dan Sastra Indonesia Jurnal EduHealth JIDAN (JURNAL ILMIAH KEBIDANAN) Indonesian Research Journal on Education Jurnal Kebidanan, Keperawatan dan Kesehatan (J-BIKES) Health Dynamics EDUCATIONE: Journal of Education Research and Review Seroja Husada: Jurnal Kesehatan Masyarakat Jurnal Medika Veterinaria
Safitri, Rani
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Journal : Jurnal Medika Veterinaria

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The Effect of Administration of Lactobacillus Probiotics on Secretoric Immunoglobulin A (s-IgA) Levels in Female Wistar Post Ovariectomy Safitri, Rani; Aksohini Wijayanti, Tut Rayani
Jurnal Medika Veterinaria Vol 19, No 1 (2025): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v19i1.40285

Abstract

Ovariectomy is a commonly performed medical procedure to investigate the effects of estrogen loss on the immune system. Secretory immunoglobulin A (s-IgA) is an antibody that is important in mucosal defense system. Probiotics, such as Lactobacillus, have been known to affect the local immune system. This study aims to evaluate the effect of administering Lactobacillus probiotics on s-IgA levels in Wistar rats undergoing ovariectomy. Female Wistar rats (n=30) were randomly divided into two groups, namely the treatment group (receiving Lactobacillus probiotics) and the control group (receiving placebo). After undergoing an ovariectomy, treatment was given for 4 weeks. After the treatment period, s-IgA levels were evaluated using the ELISA technique in mouse saliva samples. The results showed that the treatment group receiving Lactobacillus probiotics had significantly higher s-IgA levels than the control group (p 0.05). Administration of Lactobacillus probiotics can increase s-IgA levels in Wistar rats undergoing ovariectomy. This shows the potential of probiotics in enhancing mucosal immune responses in conditions associated with estrogen deficiency
Co-Authors Amalia, Waifti Anggraeni, Tyas Astutik, Rini Bianti, Nur Dukomalamo, Purnawati Edi Rohaedi Hidayat, Elin Hutabarat, Sintong H. Iffa, Okta Imtizil Jayanti, Ade Indra Keswara, Nila Widya Khoirunnisa, Addina Lario, Shevani Hoa Tio Lilik Lestari Marhum, Sultan Setiawan Maulida, Kamila Rizka Maulina, Rifzul Nariswari, Nuzul Dian Neng Sholihat Painem, Painem Purwanto, Hadi Rahmayanti, Elifa Ihda Reny Retnaningsih Rosyidah Alfitri Safitri, Rika Ayu Saputra, Andri Dwi Saranianingsi, Ullin Tut Rayani Aksohini Wijayanti Valiananastiti, Dita Wahyuningsih, Ina Yenni Yenni Zahro, Ria Fatimatuz