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All Journal Business and Economic Publication Journal of Social Science and Multidisciplinary Analysis Jurnal Informatika dan Kesehatan International Journal of Contemporary Sciences (IJCS) JES-TM Social and Community Service
Rofiq, Abd
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ANALISIS KRONOFARMAKOLOGI PENGGUNAAN PARACETAMOL PADA PASIEN COVID-19 DI RSUD DR. SOEDOMO TRENGGALEK Prasetyawan, Fendy; Saristiana, Yuneka; Muslikh, Faisal Akhmal; Mildawati, Ratna; Oktadiana, Isma; Arifin, Chandra; Rofiq, Abd; Febriana, Laela; Besan, Emma jayanti; Fadel, Muhammad Nurul
Journal of Social Science and Multidisciplinary Analysis Vol. 1 No. 1 (2024): Journal of Social Science and Multidisciplinary Analysis (Jossama), February 20
Publisher : Noble Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The global COVID-19 pandemic has presented complex challenges to global health. Dr. Soedomo Regional General Hospital in Trenggalek has actively engaged in managing COVID-19 patients. This study aims to analyze the chronopharmacology of paracetamol usage in COVID-19 patients at the hospital, focusing on the body's biological response to the drug at various time points within the 24-hour cycle. In the treatment of COVID-19, the use of paracetamol has become a primary strategy for addressing symptoms such as fever. However, it is crucial to understand how the timing of paracetamol administration can influence the body's response to the treatment. A chronopharmacological study involving 100 patients analyzed body temperature before and after therapy at three different times: 08:00 AM, 04:00 PM, and 10:00 PM. The results revealed a significant decrease in body temperature after therapy, particularly at 04:00 PM. These findings support the concept of "the right time, the right dose" in clinical practice. Analysis of the body's circadian rhythm emphasizes the need to consider the timing of drug administration to achieve optimal outcomes. Despite the limited sample size, this research provides a foundation for the development of more precise practical guidelines for administering paracetamol to COVID-19 patients.
Analisis Cost-Benefit Terapi Simvastatin dengan Atorvastatin pada Pasien Dislipidemia di Apotek 71 Kota Kediri dengan Pendekatan Human Capital Method Prasetyawan, Fendy; Saristiana, Yuneka; Mildawati, Ratna; Fadel, Muhammad Nurul; Besan, Emma Jayanti; Astutik, Widhi; Arifin, Chandra; Rofiq, Abd; Rhomah, Eka Hayati
Business and Economic Publication Vol. 3 No. 2 (2025): Business and Economic Publication
Publisher : Fakultas Ekonomi Universitas KH. A. Wahab Hasbullah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32764/bep.v3i2.1571

Abstract

This study aims to analyze the cost-benefit of simvastatin therapy compared to atorvastatin in dyslipidemia patients at Apotek 71 Kediri City using the Human Capital Method. Using a cross-sectional study design, this study analyzed 60 patients (30 simvastatin users, 30 atorvastatin users). Productivity loss data was collected through a patient self-report questionnaire and valued monetarily using the assumption of a uniform daily wage. Results showed that direct costs of simvastatin were lower (IDR 75,000/month) than atorvastatin (IDR 210,000/month), but lost productivity in the simvastatin group was higher (IDR 384,000) than atorvastatin (IDR 180,000). The Net Benefit value of simvastatin therapy was -Rp 39,000 with a Benefit Cost Ratio (BCR) of 0.91, while atorvastatin produced a Net Benefit of +Rp 210,000 with a BCR of 1.54. The difference in Net Benefit was statistically significant based on an independent t-test (p=0.002). Thus, atorvastatin is more economically efficient than simvastatin because it provides higher productivity benefits despite higher direct costs.
Sosialisasi Tingkat Kesadaran dan Pengetahuan Masyarakat Tentang Manfaat Teh Kombucha Dalam Mengatasi Sleep Paralysis Selama Pandemi COVID-19 Saristiana, Yuneka; Prasetyawan, Fendy; Arifin, Chandra; Rofiq, Abd; Astutik, Widhi; Azis, Asrizal; Tri Wulan, Ema
Journal of Social and Community Service Vol. 1 No. 3 (2022): July 2022
Publisher : Faculty of Engineering University of Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jestmc.v1i3.149

Abstract

This community service program aims to enhance public understanding and knowledge about sleep paralysis and the benefits of kombucha tea during the COVID-19 pandemic. Conducted throughout January 2021, the program involved various socialization activities such as presentations, workshops, and discussions. Post-activity evaluations showed a significant improvement in public understanding of sleep paralysis and the benefits of kombucha tea. Prior to the program, most respondents had limited knowledge about sleep paralysis and kombucha tea, but after participating, their understanding increased significantly. Despite facing some challenges, the overall results of this program indicate that socialization about sleep paralysis and the benefits of kombucha tea can be effective in enhancing public understanding of sleep health and nutrition during the COVID-19 pandemic.
Community Empowerment Through Increasing Knowledge About the Truth of the Drug NZT-48 as a Neurotrophic in Increasing Brain Potential: Pengabdian Masyarakat Melalui Peningkatan Pengetahuan Tentang Kebenaran Obat NZT-48 sebagai Neurotropik dalam Meningkatkan Potensi Otak Saristiana, Yuneka; Prasetyawan, Fendy; Mildawati, Ratna; Arifin, Chandra; Rofiq, Abd; Astutik, Widhi
Journal of Social and Community Service Vol. 3 No. 3 (2024): November 2024
Publisher : Faculty of Engineering University of Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jestmc.v3i3.196

Abstract

The community service aimed to bridge the gap between scientific knowledge and public perception regarding nootropics. Through a comprehensive approach involving meticulous planning, community engagement, educational activities, expert consultations, feedback collection, and evaluation, the program sought to increase awareness and understanding of cognitive enhancement substances among participants. Real-life case studies and guest lectures by renowned experts enriched the learning experience, addressing scientific, ethical, and social perspectives. The proactive involvement of community leaders and an effective awareness campaign ensured high participation and relevance. It underscored the importance of a multidisciplinary approach in addressing complex topics and highlighted the value of engaging communities in meaningful discussions about health and well-being. The program not only educated the community about the realities and myths surrounding NZT-48 and other nootropics but also promoted critical thinking and informed decision- making. By empowering the community with accurate information and fostering a culture of informed skepticism, the program contributed to the betterment of community health and well-being, setting a precedent for future public health education initiatives.
Studi Analisa Kronofarmakologi Penggunaan Obat Ibuprofen pada Pasien Covid-19 di Rawap Inap RSUD Dr. Soedomo Trenggalek Fendy Prasetyawan; Yuneka Saristiana; Faisal Akhmal Muslikh; Ratna Mildawati; Chandra Arifin; Abd Rofiq; Emma Jayanti Besan; Muhammad Nurul Fadel; Charliandri Saputra Wahab; Muhammad Alviyan Shutiawan
Jurnal Informatika dan Kesehatan Vol. 1 No. 1 (2024): IKN : Jurnal Informatika dan Kesehatan
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/ikn.v1i1.3024

Abstract

The global COVID-19 pandemic has presented unprecedented challenges to global health. The Dr. Soedomo Regional General Hospital in Trenggalek has been at the forefront of managing COVID-19 patients, with a primary focus on the use of ibuprofen to alleviate symptoms such as fever and pain. Despite the widespread use of ibuprofen, knowledge regarding its interaction with the circadian rhythm, especially in COVID-19 patients, remains limited. This study employed an analytical observational approach with a Cross-Sectional design to analyze the use of ibuprofen in COVID-19 patients at Dr. Soedomo Regional General Hospital in Trenggalek. The study included 100 patients, emphasizing body temperature at three different times. Data analysis revealed a significant decrease in body temperature after therapy, particularly at 4:00 PM. These findings lay the foundation for the development of more targeted and personalized treatment strategies by understanding the body's response patterns to therapy at different times.   Abstrak Pandemi global COVID-19 telah menciptakan tantangan kesehatan global yang belum pernah terjadi sebelumnya. Rumah Sakit Umum Daerah Dr. Soedomo di Trenggalek telah menjadi pusat perhatian dalam menangani pasien COVID-19. Fokus utama adalah penggunaan ibuprofen untuk mengelola gejala, seperti demam dan nyeri. Meskipun ibuprofen umum digunakan, pengetahuan tentang interaksi dengan siklus sirkadian tubuh, terutama pada pasien COVID-19, masih terbatas. Penelitian ini menggunakan pendekatan observasional analitik dengan desain Cross Sectional untuk menganalisis penggunaan ibuprofen pada pasien COVID-19 di RSUD Dr. Soedomo Trenggalek. Hasil penelitian melibatkan 100 pasien, dengan fokus pada suhu tubuh pada tiga waktu berbeda. Analisis data menunjukkan penurunan suhu tubuh yang signifikan setelah terapi, terutama pada pukul 16.00 WIB. Hasil ini memberikan dasar untuk pengembangan strategi pengobatan yang lebih terarah dan personalisasi, dengan memahami pola respons tubuh terhadap terapi pada waktu yang berbeda.
Farmakoantartika Literature Study: Bioactivity of Pagodroma nivea on Fossil Deposits from Mujito Saristiana, Yuneka; Prasetyawan, Fendy; Mildawati, Ratna; Muslikh, Faisal Akhmal; Dhafin, Anis Akhwan; Raharjo, Susilo Margining; Arifin, Candra; Rofiq, Abd
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7593

Abstract

This report investigates the biodiversity of marine animals, focusing on extinct sponge species near Lesbos Island based on Aristotle's descriptions. Mujito, introduced in the literature review, is from the GeoMaud expedition in Antarctica. Various instrumental analysis methods, such as ESI mass spectrometry and NMR, contribute to a comprehensive understanding of the compounds, particularly in the context of Alzheimer's research. The pharmacantarctic literature study concludes that Antarctic Mumijo, particularly from Mujito fossil deposits, holds significant biomedical potential. It exhibits organic components like wax esters with notable biomedical activities, particularly in treating bone diseases. Additionally, Mumijo's composition resembles non-fossil samples, with wax esters dominating and unique components like α-glyceryl fatty alcohol ethers indicating neuroprotective potential. The research suggests promising applications in Oriental medicine, addressing wounds, skin diseases, tuberculosis, respiratory diseases, and neurological conditions like Parkinson's and Alzheimer's. Overall, Antarctic Mumijo showcases diverse biomedical prospects, emphasizing its organic components' therapeutic value
Forensic Pharmacy Case Study: Identification of Hazardous Mercury Content as a Whitening Agent in Beauty Cream Products Ardianto, Nanda; Prasetyawan, Fendy; Saristiana, Yuneka; Muslikh, Faisal Akhmal; Mildawati, Ratna; Dhafin, Anis Akhwan; Arifin, Candra; Rofiq, Abd
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7594

Abstract

Forensic pharmacy is crucial in identifying hazardous substances like mercury in beauty products. Counterfeit items with mercury pose health risks, emphasizing the need for accurate identification methods. The research, employing content analysis, focuses on illegal cosmetics containing mercury, aiming to understand distribution patterns and assess associated health risks. This systematic approach provides valuable insights into public health issues, contributing to safer regulatory practices. The utilization of these products may pose serious health risks to consumers. The implicated products include Temulawak New Day & Night, CAC Glow, Natural 99, HN (Day & Night), SP Special UV Whitening, Dr Original Pemutih, Super DR Quality Gold SPF 30, Diamond Cream, Herbal Plus New Day & Night, Ling Zhi Day & Night, Sj Sin Jung, Tabita, and Krim Labella. In Indonesia, the use of mercury in cosmetic products is prohibited by legislation, such as Law Number 32 of 2009 on Environmental Protection and Government Regulation of the Republic of Indonesia Number 81 of 2016 on the Security of Industrial Chemicals. Additionally, BPOM, responsible for overseeing drugs, food, and cosmetics, has issued relevant regulations
Pharmacy Philosophy in the Law of Power: The Morality of Pharmaceutical Ethics towards Rhetoric of Logic Hakim, Adiyansyah Lukman; Prasetyawan, Fendy; Saristiana, Yuneka; Muslikh, Faisal Akhmal; Dhafin, Anis Akhwan; Mildawati, Ratna; Arifin, Candra; Rofiq, Abd
International Journal of Contemporary Sciences (IJCS) Vol. 1 No. 2 (2023): December 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijcs.v1i2.7595

Abstract

Pharmacy's evolution relies on technical and philosophical aspects. Research delves into the intricate link between pharmaceutical philosophy and legal power, emphasizing moral values in daily practice. The study aims to enhance policies, regulatory frameworks, and awareness, optimizing pharmacy's pivotal role in healthcare services. The results of this study depict an investigation and comprehension of the close interconnection between the philosophy of pharmacy, the law of power, the morality of pharmaceutical ethics, and rhetorical logic. A profound integration of these four aspects can provide a solid foundation for the development of ethical policies, maintaining the integrity of the pharmacy profession, and maximizing benefits for society. A deeper understanding of the complexity of these relationships can help shape a more sustainable and ethical future in the field of pharmacy. The findings of this research depict the complexity of these relationships, highlighting that deep integration can provide a solid foundation for ethical policies and the sustainable future of pharmacy
Co-Authors Anis Akhwan Dhafin Ardianto, Nanda Astutik, Widhi Azis, Asrizal Besan, Emma Jayanti Candra Arifin, Candra Chandra Arifin Charliandri Saputra Wahab Emma Jayanti Besan Faisal Akhmal Muslikh Febriana, Laela Fendy Prasetyawan Hakim, Adiyansyah Lukman Mildawati, Ratna Muhammad Alviyan Shutiawan Muhammad Nurul Fadel Oktadiana, Isma Raharjo, Susilo Margining Ratna Mildawati Rhomah, Eka Hayati Tri Wulan, Ema Yuneka Saristiana