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All Journal Jurnal Farmasi Udayana Jurnal Sains dan Teknologi Pharmaciana: Jurnal Kefarmasian Farmasains : Jurnal Ilmiah Ilmu Kefarmasian JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Riset Kesehatan Nasional Jurnal Ilmiah Medicamento Jurnal Penelitian Agama Hindu Jurnal Kesehatan Primer JRKN Usadha Borneo Journal of Pharmacy Jurnal Kesehatan Primer
Dwi Arymbhi Sanjaya
Universitas Mahasaraswati Denpasar
Religion Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Antidepressant-Like Activity and Physicochemical Analysis of Essential Oils from Michelia alba and Plumeria alba Flowers Nayaka, Ni Made Dwi Mara Widyani; Swari, Ni Luh Putu; Widnyani, Dewa Ayu Sri Bintang; Sukmayanti, Ni Kadek; Yuda, Putu Era Sandhi Kusuma; Wardani, I Gusti Ayu Agung Kusuma; Sanjaya, Dwi Arymbhi
JST (Jurnal Sains dan Teknologi) Vol. 11 No. 2 (2022)
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (270.576 KB) | DOI: 10.23887/jstundiksha.v11i2.45291

Abstract

Depression is a mental disorder with an increased prevalence. Other than conventional antidepressants, essential oils have been used in aromatherapy as a complementary and alternative medicine to reduce depression. In the current study, the antidepressant-like activity of the inhalation of essential oils from Michelia alba (MAEO) and Plumeria alba (PAEO) flowers was analyzed using the forced swim test. The immobility time of mice from tested groups was evaluated statistically by the non-parametric Kruskal Wallis test, followed by the Mann Whitney post hoc test. Also, the characterization of both essential oils was determined by refractive index, solubility, and Gas Chromatography-Mass Spectrophotometry (GC-MS) analysis. PAEO showed stronger antidepressant-like activity than MAEO (p<0.05) and it was equal to the positive control (essential oil of Lavandula angustifolia) (p>0.05). The GC-MS analysis revealed some calming agents in MAEO and PAEO such as linalool, linalyl acetate, phenylethyl alcohol, and methyl anthranilate.
Antibiotic consumption and resistance: a 3-years ecological study for four critical groups of bacteria in a general regional hospital Sanjaya, Dwi Arymbhi; Siada, Nyoman Budiartha; Juanita, Rr Asih; Mahaputra, I Putu Yudistira; Kamalia, Made Gek Adisti; Meriyani, Herleeyana
Pharmaciana Vol. 14 No. 1 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i1.27321

Abstract

Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae are the most critical groups of multi-drug resistant (MDR) bacteria that cause a threat in hospitals. This study identified the trend of antibiotic consumption, antibiotic resistance pattern, and the relationship between antibiotic consumption and antibiotic resistance in a critical group of bacteria in a general regional hospital. This ecological study was based on retrospective data from inpatient databases in a general regional hospital over three years (2017-2019). The trend for annual antibiotic consumption over 2017-2019 was defined as defined daily doses/100 bed-days. The relationship between total antibiotic consumption and the percentage of antibiotic resistance among four isolated critical bacteria was explored in time series analysis and linear regression. The most frequently used antibiotic was ampicillin (220.33 DDD/100 bed-days), ciprofloxacin (126.86 DDD/100 bed-days), and ampicillin-sulbactam (126.34 DDD/100 bed-days). There was a significant relationship between antibiotic consumption (ampicillin, ampicillin-sulbactam, ceftazidime, gentamicin, amikacin, and ciprofloxacin) in DDD/100 bed-days and antibiotic resistance in E. coli, K. pneumoniae, and P. aeruginosa (p<0.05) but not statically significant in A. baumannii (p=0.062). The annual usage fluctuated or remained stable, with no statistically significant trends change. The relationship between antibiotic consumption and antibiotic resistance was significant in three out of four critical groups of bacteria.
Procedure for Using Crystalloid and Colloid Fluids in Blood Pressure in Sectio Caesaria Patients Using Spinal Anesthesia Technique Sanjaya, Dwi Arymbhi; Agustini, Ni Luh Putu Inca Buntari; Putra, I Gede Agus Shuarsedana; Lewar, Emanuel Ileatan
JURNAL KESEHATAN PRIMER Vol 3 No 2 (2018): JKP (Jurnal Kesehatan Primer)
Publisher : Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/jkp.v3i2.255

Abstract

Background: In Indonesia, the study about effectivity and side effect of colloid and crystalloid fluid have been completed, but the study about standard operating procedures (SOP) never have been done. The aim of this research was to describe and evaluate the SOP for the use of crystalloid and colloid fluids on blood pressure in sectio caesarea by using spinal anesthesia techniques. Method: The research employed a descriptive quantitative method by using a questionnaire. The basic features of crystalloid and colloid fluid selection were analyzed by multiple response tests. This research was conducted in type A hospitals in the Denpasar area by involving 30 anesthesiologist as a respondent. Result: The results indicated that 76.7% of respondents stated that there was no SOP for crystalloid and colloid fluids to prevent maternal hypotension in sectio caesarea by using spinal anesthesia techniques. In the multiple response tests, the effectiveness and side effects (21.3%) were the factors that had to be considered in the crystalloid and colloids fluid selection to prevent maternal hypotension in sectio caesarea by using spinal anesthesia techniques. The National Guideline of Medical Services for Anesthesiology and Incentive Therapy have been followed in determining the use of crystalloid and colloid fluids at section Caesarea. However, the guideline did not explain the basis for selecting crystalloid and colloid fluids to prevent maternal hypotension in sectio caesarea by using spinal anesthesia techniques in more detail, therefore the factors of effectiveness and risk of side effects are the main consideration.
Criteria for Patients using Crystalloid and Colloid Fluids in Sectio Caesaria Lewar, Emanuel Ileatan; Sanjaya, Dwi Arymbhi; Putra, I Gede Agus Shuarsedana
JURNAL KESEHATAN PRIMER Vol 3 No 2 (2018): JKP (Jurnal Kesehatan Primer)
Publisher : Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/jkp.v3i2.260

Abstract

Background: In Indonesia, the study about effectivity and side effect of colloid and crystalloid fluid have been completed, but the sample on the study was varied. The aim of this research was to describe the criteria of patient which used of crystalloid and colloid fluids on blood pressure in sectio caesarea by using spinal anesthesia techniques. Method: The research employed a descriptive quantitative method by using a questionnaire. The basic features of crystalloid and colloid fluid selection were analyzed by multiple response tests. This research was conducted in type A hospitals in the Denpasar area by involving 30 anesthesiologist as a respondent. Result: The results indicated that 100% of respondents stated that they used crystalloid for patient with allergic and they used coloid for patient with high risk edema. The result has been reviewed with The National Guideline of Medical Services for Anesthesiology and Incentive Therapy have been followed in determining the use of crystalloid and colloid fluids at section Caesarea. However, the guideline did not explain the basis for selecting crystalloid and colloid fluids to prevent maternal hypotension in sectio caesarea by using spinal anesthesia techniques, therefore the factors of effectiveness and risk of side effects are the main consideration.
Efektifitas Bilateral Packing Pada Pemasangan Laryngeal Mask Airway Klasik Pada Pasien Dengan General Anesthesia Inhalasi Lewar, Emanuel Ileatan; Suyasa, Agus Baratha; Sanjaya, Dwi Arymbhi
JURNAL KESEHATAN PRIMER Vol 5 No 1 (2020): JKP (Jurnal Kesehatan Primer)
Publisher : Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/jkp.v5i1.456

Abstract

Introduction: The anesthesiologist found the problem in classic LMA and they modified with bilateral packing, but there is no study to see the risk factor for failure in classic LMA and LMA with bilateral packing. The purpose of this study was to identify the effectiveness of bilateral packing on classic LMA use in patients with general inhalation anesthesia at Kasih Ibu Hospital Denpasar. Method: this research is a case control with a retrospective approach which is an analytical survey study with a purposive sampling technique. The variable observed in this study was the risk of leakage, biting, regardless of classic LMA installation compared to classic LMA with bilateral packing. The data used in this study are secondary data based on observations in as many as 46 cases of patients with classic LMA with bilateral packing and classic LMA listed in the medical record. Data analysis was performed with a comparative test of group data fitted with bilateral packing and the classic LMA group with the Mann-Whitney test. Results: of the analysis showed that bilateral packing was significantly effective because there was no leakage, biting, regardless event compared to the use of classic LMA (p <0.005). Conclusion: This researcher stated that the installation of LMA with bilateral packing method is very effective to prevent failures, such as leakage, biting, regardless. Pendahuluan: Hingga saat ini masih ditemukan adanya masalah dalam pemasangan LMA klasik sehingga dilakukan modifikasi yaitu dengan pemasangan bilateral packing, namun belum dilakukan kajian yang lebih mendalam untuk melihat faktor resiko kegagalan. Tujuan penelitian ini untuk mengidetifikasi efektivitas pemasangan bilateral packing pada penggunaan LMA klasik pada pasien dengan general anesthesia inhalasi di rumah sakit Kasih Ibu Denpasar. Metode: penelitian ini yaitu case control dengan pendekatan retrospektif yang merupakan suatu penelitian survei analitik dengan teknik purposive sampling. Variabel yang diamati dalam penelitian ini yaitu resiko kebocoran, tergigit, terlepas pada pemasangan LMA klasik dibandingkan dengan LMA klasik dengan bilateral packing. Data yang digunakan dalam penelitian ini merupakan data sekunder berdasarkan hasil pengamatan pada sebanyak masing-masing 46 kasus pasien dengan pemasangan LMA klasik dengan bilateral packing dan LMA klasik yang tertera pada rekam medis. Analisa data dilakukan dengan uji komparatif terhadap data kelompok yang dipasang bilateral packing dan kelompok LMA klasik dengan uji Mann-Whitney. Hasil: analisis menunjukkan bahwa pemasangan bilateral packing secara signifikan lebih efektif karena tidak ada kejadian kebocoran, tergigit, dan terlepas (p<0,005) dibandingkan dengan penggunaan LMA Klasik. Kesimpulan: Peneliti ini bahwa pemasangan LMA dengan metode bilateral packing sangat efektif yang dilakukan untuk mencegah kegagalan antara lain terlepas, bocor dan tergigit.
Co-Authors AA Istri Mas Padmiswari Agus Baratha Suyasa Asthadi Mahendra Bhandesa, Asthadi Mahendra Chusna, Nurul Emanuel Ileatan Lewar Erna Cahyaningsih Fitria Megawati Herleeyana Meriyani I Gede Agus Shuarsedana Putra I Putu Yudistira Mahaputra Ida Ayu Manik Damayanti Kamalia, Made Gek Adisti Ketupapa, Florentina Gabriela Ketut Agus Adrianta LEWAR, EMANUEL ILEATAN Luh Risma Putri Rahayu Made Agus Deny Mahendra Putra Made Gek Adisti Kamalia Mahaputra, I Putu Yudistira Mahaputra, Yudistira Mendra, Ni Nyoman Yudianti Meriyani, Herleeyana Ni Kadek Sukertiasih Ni Luh Kade Arman Anita Dewi Ni Luh Putu Inca Buntari Agustini Ni Made Dwi Mara Widyani Nayaka Ni Made Wiwik Setiawati Ni Wayan Sukma Antari Noviani, Lusy Nyoman Budiartha Siada Puspawati, Made Putra, I Gede Agus Shuarsedana Putu Era Sandhi Kusuma Yuda Putu Sukma Purnamasari RR. Asih Juanita Sukmayanti, Ni Kadek Suyasa, Agus Baratha Swari, Ni Luh Putu Triska Ananda Rahayu Wardani, I Gusti Ayu Agung Kusuma Widnyani, Dewa Ayu Sri Bintang