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All Journal Lontar Komputer: Jurnal Ilmiah Teknologi Informasi Jurnal Farmasi Klinik Indonesia Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi) Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Syntax Literate: Jurnal Ilmiah Indonesia JSFK (Jurnal Sains Farmasi & Klinis) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Ilmu Kefarmasian Indonesia Majalah Farmasetika Kumawula: Jurnal Pengabdian Kepada Masyarakat Pharmacoscript Jurnal Ners Journal of Parasite Science Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Karya Abdi Masyarakat Jurnal Pengabdian Masyarakat Jurnal Sains dan Kesehatan Jurnal Pengabdian Masyarakat Inovatif Jurnal Pengabdian Masyarakat Inovatif
Najwa Rokhmah, Nisa
Universitas Pakuan
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Penilaian Efektivitas Antihipertensi dan Efek Samping Obat di RSUP Fatmawati Indriani, Lusi; Rokhmah, Nisa Najwa; Shania, Nur
JSFK (Jurnal Sains Farmasi & Klinis) Vol 9 (2022): J Sains Farm Klin 9(suplemen), Desember 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.sup.146-151.2022

Abstract

Hipertensi diartikan sebagai kondisi ketika tekanan darah mencapai atau melebihi 140/90mmHg. Dalam keputusan penggunaan obat selalu mempertimbangkan manfaat dan resikonya. Obat antihipertensi dianggap efektif jika dapat mengontrol tekanan darah. Pada penggunaan obat antihipertensi jangka panjang perlu diwaspadai kemungkinan adanya efek samping. Penelitian ini bertujuan untuk menilai efektivitas dan efek samping obat antihipertensi menggunakan data rekam medis pasien rawat inap di RSUP Fatmawati. Penelitian ini bersifat observasional (non eksperimental). Penentuan efektivitas menggunakan desain pre dan post, dan rancangan cross sectional untuk mengidentifikasi efek samping obat dengan pendekatan secara retrospektif. Pengambilan sampel ditentukan secara purposive berdasarkan kriteria tertentu. Data yang diperoleh dianalisis secara univariat dan bivariat dengan pengujian Wilcoxon, uji Spearman dan uji Fisher’s Exact. Studi ini memberikan hasil bahwa mayoritas pasien rawat inap di RSUP Fatmawati berjenis kelamin perempuan, umumnya menderita hipertensi tingkat 2, lebih banyak mendapatkan terapi gabungan. Terdapat perbedaan tekanan darah sebelum dan setelah pemberian terapi antihipertensi (p<0,05)[A1] [A2] . Kejadian efek samping obat akibat penggunaan antihipertensi ditemukan sebanyak 16%. Tidak ada hubungan yang bermakna antara jenis terapi antihipertensi dengan kejadian efek samping obat.
Effectiveness of nutmeg flesh extract (Myristica fragrans H) as an immunomodulator using the carbon clearance method in mice (Mus musculus) Rokhmah, Nisa Najwa; Herlina, Nina; Ananda, Syindi Yulia
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 2 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i2.1517

Abstract

Nutmeg (Myristica fragrans H) is composed of secondary metabolite compounds, among which flavonoids significantly contribute to its immunomodulatory properties. Using the carbon clearance method, this study aims to determine the efficacy of nutmeg flesh extract (NFE) as an immunomodulator. Negative control (Na-CMC 0.5%), normal control (Na-CMC 0.5%), immunostimulant positive control (Imboost® Force 0.91mg/20 g BW of mice), immunosuppressant positive control (methylprednisolone® 0.015 mg/20 g BW of mice), dose I (5 mg/20 g BW of mice), dose II (10 mg/20 g BW of mice), and dose III (20 mg/20 g BB mice) comprised the seven groups of 35 white male mice (DDY). The assessed parameters included organ index, absorbance, and the phagocytosis constant and index. The immunostimulant effect of NFE was demonstrated by the phagocytosis index values of 1.225 (indicating moderate immunostimulation), 1.512 (indicating moderate immunostimulation), and 2.202 (indicating strong immunostimulation) for NFE dose I, II, and III, respectively. The lymphoid organ index may have increased among the three NFE treatment groups, according to the results of organ index measurements. We can conclude, Nutmeg Flesh Extract (NFE) has an immunomodulatory effect in the immunostimulant category, as well as increased phagocytosis activity and lymphoid organ index.
Evaluation of The Suitability of High-Alert Medication Storage in the Pharmaceutical Warehouse of the Indonesian Red Cross (PMI) Bogor Hospital Elfrida, Nyayu Siti Aminah Lily; Baladraf, Alya Ramadhani; Rokhmah, Nisa Najwa
Jurnal Ners Vol. 9 No. 2 (2025): APRIL 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i2.40356

Abstract

The storage of high-alert medications requires evaluation to prevent medication errors and inappropriate drug use and to facilitate the monitoring as well as control of these medications. Hospitals need to develop policies for managing high-alert medications. Therefore, the storage system must be established and aligned with actual conditions to ensure accurate drug delivery. This study aimed to describe the storage of high-alert medications in the pharmacy warehouse of PMI Bogor Hospital in 2023, determine the level of compliance with the storage of high-alert medications, assess the impact of storage practices on drug damage, and describe the knowledge and behavior of warehouse staff regarding high-alert medication storage. The results showed that the average compliance rates were as follows: 71% for Look-Alike Sound-Alike (LASA) medications (good), 73% for high-concentration electrolytes (good), 88% for narcotics (very good), 76% for psychotropics (good), and 75% for precursors (good). The staff's knowledge was rated as very good, with an average score of 9.17, while their behavior was rated as good, with a score of 9.5.
Pemberdayaan Ibu-Ibu Posyandu Untuk Pemanfaatan Buah Lokal Dalam Upaya Peningkatan Kualitas Kesehatan Ibu Hamil Andini, Septia; Rokhmah, Nisa Najwa; Yulianita, Yulianita
Jurnal Karya Abdi Masyarakat Vol. 4 No. 3 (2020): Jurnal Karya Abdi Masyarakat
Publisher : LPPM Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (109.206 KB) | DOI: 10.22437/jkam.v4i3.11578

Abstract

Anemia dan tekanan darah tinggi menjadi salah satu penyakit penyerta selama kehamilan yang dapat meningkatkan resiko angka kematian ibu dan anak (AKI) dan setelah melahirkan penyakit tersebut memiliki prevalensi untuk tetap muncul pada beberapa ibu. Kedua penyakit penyerta tersebut dapat dicegah dan ditangani dengan konsumsi vitamin maupun obat secara teratur dan dengan melakukan pola hidup sehat. Salah satu gambaran pola hidup Ibu hamil di kelurahan Pakansari adalah cenderung memilih makanan dan minuman tanpa mempertimbangkan nilai gizi dan manfaatnya. Pola makan dan minum tersebut dapat memperburuk kondisi serta memicu timbulnya penyakit penyerta selama kehamilan. Tujuannya adalah untuk memberikan edukasi kepada ibu hamil mengenai manfaat buah untuk ibu hamil dan melakukan demo pembuatan makanan dan minuman berbahan dasar buah. Metode yang dilakukan dalam penelitian ini yaitu: melakukan observasi, memilih obyek pengabdian, mengumpulkan data obyek pengabdian, mengisi kesediaan mengikuti kegiatan pemeriksaan dini dan penyuluhan dengan mengisi kuisioner, melaksanakan kegiatan penyuluhan dan pelayanan kesehatan. Hasil penelitian ini menunjukan bahwa pengetahuan ibu hamil mengenai manfaat buah masih sangat kurang, kurangnya pengetahuan ibu hamil mengenai manfaat buah-buahan ini dapat menjadi penyebab hanya sekitar 50% ibu hamil yang mengkonsumsi buah setiap hari dan pengetahuan tentang pengolahan buah masih sangat kurang berdasarkan hasil data kuisioner 85% mengkonsumsi buah dengan cara dimakan langsung.
Hubungan Penggunaan Obat Pendamping Gagal Ginjal Kronik terhadap Kualitas Hidup Pasien Lansia RSUD M. Yunus Bengkulu yang Menjalani Hemodialisis Rokhmah, Nisa Najwa; Gunawan, Dewi Oktavia; Rahmadania, Aisyah
Indonesian Journal of Clinical Pharmacy Vol 12, No 3 (2023)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/ijcp.2023.12.3.47343

Abstract

Menurunnya aktivitas ginjal yang bersifat progresif dan irreversible disebut dengan gagal ginjal kronis. Hemodialisis merupakan satu dari berbagai contoh terapi pengganti ginjal yang seringkali dipilih oleh pasien dan umumnya prosedur tersebut disertai dengan penambahan obat pendamping. Penelitian ini bertujuan untuk mengetahui karakteristik pasien dan penggunaan obat pendamping, kualitas hidup pasien, dan hubungan penggunaan obat pendamping terhadap kualitas hidup pasien serta hubungan variabel karakteristik terhadap kualitas hidup pasien. Penelitian berjenis deskriptif observasional ini dilakukan pada bulan Maret–April 2022 secara cross-sectional, serta pengambilan data secara prospektif melalui kuesioner WHOQOL-BREF dan wawancara. Populasi pada pasien hemodialisis di RSUD M. Yunus Bengkulu sebanyak 73 pasien. Hasil penelitian menunjukkan 52 pasien yang termasuk ke dalam kriteria inklusi serta terdapat 33 (63,5%) pasien perempuan dan 19 (36,5%) pasien laki-laki dengan usia yang paling dominan, yaitu lansia awal 46–55 tahun sebanyak 18 pasien (34,6%). Berdasarkan obat pendamping pasien yang menjalani hemodialisis, ditemukan bahwa sebagian besar pasien menggunakan kombinasi asam folat, B kompleks, dan CaCO3 (42,3%); kombinasi CaCO3 dan asam folat (38,5%); tidak mengonsumsi obat pendamping (19,2%). Hasil penilaian kualitas hidup menunjukkan bahwa kelompok yang menggunakan kombinasi asam folat, B kompleks dan CaCO3 memiliki kualitas hidup sangat baik; kelompok kombinasi CaCO3 dan asam folat memiliki kualitas hidup baik; sedangkan yang tidak mengonsumsi obat memiliki kualitas hidup cukup. Berdasarkan analisis statistik dari data penelitian yang didapatkan, diketahui bahwa terdapat hubungan yang signifikan antara penggunaan obat pendamping terhadap kualitas hidup (p=0,000). Faktor karakteristik pasien (usia, jenis kelamin, komorbid dan lamanya menjalani terapi hemodialisis) memiliki hubungan dengan kualitas hidup pasien.
The Rationality of Antibiotics Use on Acute Diarrhea to Pediatric Inpatients in the Fatmawati Hospital for 2018-2019 Period: Studi Penggunaan Obat Antibiotik Rational pada Diare Akut untuk Pasien Rawat Inap Anak di RS. Fatmawati Periode 2018-2019 Rokhmah, Nisa Najwa; Manuel, Yovania Grace Priskila; Putri Kusuma, Ema Nillafita; Nurdin, Naufal Muharam
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 8 No. 1 (2022): (March 2022)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2022.v8.i1.15684

Abstract

Background: Diarrhea is characterized by an increase in the frequency of bowel movements more than three times a day. This disease has a fairly high incidence rate in Indonesia, especially in children. One of the causes of diarrhea is a bacterial infection, therefore it needs to be treated with antibiotics. Several studies show that there are still many antibiotics that are used irrationally. It is necessary to analyze the rationality of the use of antibiotics in pediatric patients with diarrhea using the Gyssens method Objectives: This study is to ascertain the profile of acute diarrhea pediatric patients characteristic and evaluate antibiotics rationality with Gyssens method. Moreover, the purpose of this study is to analyze the factors that influence the rationality of the use of antibiotics in the inpatient pediatric acute diarrhea installation of Fatmawati Hospital 2018-2019 period. Material and Methods: This study is descriptive observational research. The study design was cross-sectional with retrospective data collection which was analysed then qualitatively with the Gyssens flow method Results: The result showed 54,29% antibiotics usde appropriately and rational. The irrational use of antibiotics was 45.7%. The results of statistical analysis with chi-square show a significant relationship between the rationality of antibiotics and the type of antibiotic (ρ = 0.000 < 0.05) and multiple logistic regression analysis showed that the route of drug administration (ρ = 0.000 < 0.05) affected the rationality of antibiotics use. Conclusions: Less than 50% of the patients received irrational treatment according to the Gyssen flow chart and according to the results of statistical analysis, the type of antibiotic and the route of drug administration affected the rationality of antibiotics.
Potential Anthelmintic Activity of Pineapple Fruit (Ananas comosus) and Mango Leaves Juice (Mango foliorum) against Ascaridia galli Worms In-Vitro Model Rahminiwati, Min; Martha Arofa Dilla; Nisa Najwa Rokhmah
Journal of Parasite Science Vol. 9 No. 2 (2025): Journal of Parasite Science
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jops.v9i2.63604

Abstract

Ascaridia galli is a worm that infects the chickens' digestive tract, leading to various problems such as worsening feed efficiency, slowing poultry growth, and increasing mortality. Mango leaves and pineapple fruit were reported to have anthelmintic activity against A. galli. These two plants contain secondary metabolites that were suggested to have synergistic effects. This study aimed to determine the potential activity of combining arumanis mango leaf and pineapple juice against A. galli and evaluate their interaction based on anthelmintic activity profile. The activity of 40% pineapple fruit juice (PA) added with different concentrations of arumanis mango leaf juice (AM) from 0.13%, 0.26%, and 0.52% v/v, and pineapple fruit juice at concentrations 20, 40% v/v were mixed with 0.26% arumanis mango leaf juice. as well as NaCl 0,9%  as negative control and pyrantel pamoate 0.2; 0.4; 0.8 % b/v as a positive control respectively were determined. Observation on worm mortality was conducted in 15-minute intervals for 300 minutes. The time-a cumulative mortality rate of worm curve exposed to PA 40 %   was shifted to the left in the presence of AM, and AM 0.26 % curve in the presence of PA. The best, LC50, LT50, and L100 were found in AM 0.52 % combined with PA 40%. This finding showed the potential activity of pineapple fruit juice at 40% combined with arumanis mango leaf juice at 0.52 %  as the best combination in which anthelmintic activity occurs due to synergism interaction between arumanis mango leaf juice and pineapple fruit juice.
Health services in an effort to control degenerative diseases in the Pakansari Cibinong sub-district Andini, Septia; Najwa Rokhmah, Nisa; Nurmala, Sara; Fatmi, Mindiya; Ambarwati, Rini; Herlina, Nina; Nurhikmah, Wilda; Wahyuningrum, Cyntia
Jurnal Pengabdian Masyarakat Inovatif Vol. 1 No. 2 (2023): JPMI (Jurnal Pengabdian Masyarakat Inovatif)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/jpmi.v1i2.70

Abstract

Health is one of the basic human needs that is important to maintain. With good health conditions, humans can carry out activities and fulfill other life needs well. Health services are a dynamic activity in the form of helping the community in monitoring the scale of their health. Health services are efforts carried out jointly to maintain and improve health, prevent and cure disease, and increase public attention to their health conditions. Degenerative is a group of diseases in which there is a change in the function of certain parts of the body. As age increases, body function also decreases, so that degenerative diseases cannot be avoided. The dominant risk factor for degenerative diseases is heredity. Exercise habits and the habit of consuming balanced nutrition will also help with a healthy and good aging process. The aim of this service activity is so that people in the Pakansari Cibinong sub-district who take part in the activity can know the importance of knowing their health conditions and also raise awareness among the people in the Pakansari Cibinong sub-district regarding their health conditions. Activities carried out at community service events for the community in Cibinong sub-district are general health checks, Body Mass Index (BMI) checks, blood pressure checks, blood sugar checks and uric acid checks. There were 38 people who took part in the activity, including 26.3% men and 73.7% women. From the results of the examination, it was found that 39.5% of participants had a normal BMI, 47.4% were overweight and 13.2% were obese. Hypertensive conditions were found to be dominant in pre-hypertensive conditions, namely with a percentage of 29.7%. Blood sugar conditions were found to be hypertension, namely with a percentage of 86.5% and uric acid conditions were dominated by participants who had normal conditions with a percentage of 64.9%.
Health services in an effort to control degenerative diseases in the Pakansari Cibinong sub-district Andini, Septia; Najwa Rokhmah, Nisa; Nurmala, Sara; Fatmi, Mindiya; Ambarwati, Rini; Herlina, Nina; Nurhikmah, Wilda; Wahyuningrum, Cyntia
Jurnal Pengabdian Masyarakat Inovatif Vol. 1 No. 2 (2023): JPMI (Jurnal Pengabdian Masyarakat Inovatif)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/jpmi.v1i2.70

Abstract

Health is one of the basic human needs that is important to maintain. With good health conditions, humans can carry out activities and fulfill other life needs well. Health services are a dynamic activity in the form of helping the community in monitoring the scale of their health. Health services are efforts carried out jointly to maintain and improve health, prevent and cure disease, and increase public attention to their health conditions. Degenerative is a group of diseases in which there is a change in the function of certain parts of the body. As age increases, body function also decreases, so that degenerative diseases cannot be avoided. The dominant risk factor for degenerative diseases is heredity. Exercise habits and the habit of consuming balanced nutrition will also help with a healthy and good aging process. The aim of this service activity is so that people in the Pakansari Cibinong sub-district who take part in the activity can know the importance of knowing their health conditions and also raise awareness among the people in the Pakansari Cibinong sub-district regarding their health conditions. Activities carried out at community service events for the community in Cibinong sub-district are general health checks, Body Mass Index (BMI) checks, blood pressure checks, blood sugar checks and uric acid checks. There were 38 people who took part in the activity, including 26.3% men and 73.7% women. From the results of the examination, it was found that 39.5% of participants had a normal BMI, 47.4% were overweight and 13.2% were obese. Hypertensive conditions were found to be dominant in pre-hypertensive conditions, namely with a percentage of 29.7%. Blood sugar conditions were found to be hypertension, namely with a percentage of 86.5% and uric acid conditions were dominated by participants who had normal conditions with a percentage of 64.9%.
Co-Authors -, Yulianita . Yulianita, . Ambarwati, Rini Ananda, Syindi Yulia Baladraf, Alya Ramadhani Cintya Wahyuningrum Dewi Oktavia Gunawan Dwi Indriati Elfrida, Nyayu Siti Aminah Lily Halimah Tus Sadiah Hijib Sihabullah Indriani, Lusi Manuel, Yovania Grace Priskila Mario Yohanes Winarto Martha Arofa Dilla Mindiya Fatmi MOERFIAH . Moh Fauzan Jauhari Suherlan Muhamad Saad Nurul Ishlah Naufal Muharam Nurdin Nhestricia, Nhadira Nina Herlina Nina Herlina Ningsih, Whidya Nurhikmah, Wilda Nurmala, *Sara Putri Kusuma, Ema Nillafita Rahmadania, Aisyah Rahminiwati, Min Rikkit Rini Ambarwati Rizki Alam Putra Sara Nurmala Septia Andini Shania, Nur Venny Hapsari, Veronica Wahyuningrum, Cyntia Wilda Nurhikmah Yulianita Yulianita Yulianita Yulianita Yulianita, Yulianita