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All Journal Jurnal Farmasi Udayana Majalah Obat Tradisional Jurnal Surya Medika PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Ahmar Metastasis Health Journal (AMHJ) Journal Of Human And Education (JAHE) JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Jurnal Katalisator Jurnal Pengabdian Masyarakat Bangsa Herbal Medicine Journal JPS (Jurnal Pharma Saintika) Jurnal Bakti Nusantara

Elfasyari, Trie Yuni

Akademi Dwi Farma

Author-ID : 1311700

Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Identifikasi Bakteri Escherichia coli Susu Kedelai Murni di Pasar Jodoh Kota Batam Sri Hainil; Trie Yuni Elfasyari; Rofina Intan Sulistya
Jurnal Surya Medika (JSM) Vol 7 No 1 (2021): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i1.2155

Pure soy milk is a highly nutritious drink; in general, pure soy milk contains excellent content for the body in the form of protein, iron, phosphorus, carbohydrates, fat, provitamin A and B vitamins. Causing pure soy milk to contain or be contaminated with microorganisms. one of the microorganisms found in drinks or water is the Coliform bacteria. An example of Coliform bacteria is Escherichia coli. Escherichia coli is a bacterium that lives in the human intestine; these bacteria live as normal flora or can be called a collection of microorganisms, naturally present in normal and healthy human bodies. The research objective was to determine the presence or absence of Escherichia coli in pure soy milk sold in Jodoh Market, Batam City. This study uses the Most Probable Number (MPN) method. The results of the study on 10 samples of pure soy milk A, B, C, D, E, F, G, H, I, J and 2 samples of soy milk branded K, and L contained coliform bacteria, and there were 6 Escherichia coli bacteria in soy milk samples. Pure A, B, C, D, G, and on samples of soy milk branded K. The results of the examination of 12 samples of soy milk were found not to meet the requirements of the Indonesian National Standard (INS 01 – 3830 – 1995).

Penetapan Kadar Flavonoid Total Pada Beberapa Bagian Tanaman Kepel (Stelecocharpus burahol Hook F. & Th) Trie Yuni Elfasyari
Jurnal Farmasi Udayana Vol. 8, No. 2, Tahun 2019
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Kepel, Stelecocharpus burahol Hook F. & Th are originally grows in Indonesia. This plant is usually found in the Palace at Java island. Kepel has its own phylosophical meaning for the Palace, and the fruit is useful to maintain the beauty of princes of the Palace, the leaves are also nutritious to decrease cholesterol level. Efficacy of kepel is due to its contain active substance suchs us flavonoids, saponins, tannins, alkaloids, and steroids. There are currently no detailed data about levels of flavonoids in S. burahol. It is needs to be researched for determination of total flavonoid content ethanolic extract in different parts (young leaves, old leaves and seeds ) of S. burahol. Each part of plant were extracted by soxhlet using 96% ethanol as the solvent. Preliminary tests was conducted using cellulose plates as stationary phase and the mobile phase of n-butanol-acetic acid-aquadest (4:1:5, upper phase). Total flavonoid content was determined by visible spectrophotometric using alluminium chloride as chelating agent. The result of ANOVA analysis obtained showed that the total flavonoid content in ethanolic extracts leaves (young and old) and seeds, respectively (3.32±0.12); (4.82±0.08), and (0.25±0.01)%. The 96% ethanol of old leaves extract of S. burahol showed the highest of total flavonoid content as 4.82±0.08%.

Effect of Diabetes Condition on Topical Treatment of Binahong Leaf Fraction in Wound Healing Process Kintoko Kintoko; Hanifah Karimatulhajj; Trie Yuni Elfasyari; Ersi Arviana Ihsan; Teguh Adiyas Putra; Puspawan Hariadi; Citra Ariani; Nurkhasanah Nurkhasanah
Majalah Obat Tradisional Vol 22, No 2 (2017)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Diabetes mellitus (DM) is a metabolic disease which is becoming the first number of health problem in Indonesia, based on the results of the Basic Health Research of Ministry of Health in 2013. One of the diabetes complications affected by high levels of blood glucose is diabetic ulcers wich 85% the number of cases was overed by amputation as the result of improper handling. Herbal treatments could be an alternative treatment of diabetic ulcers, one of them is binahong plant. The results of previous studies have shown the ability of ethanolic extract of binahong leaf in accelerating wound healing in diabetic rats. This study would be a continued study to test five kinds of binahong leaf fractions (FDB) with gradual solvent polarity in accelerating wound healing in diabetic ulcer. Wound healing parameters observed were percentage of wound healing from the wound diameter contraction. The test begins with ethanolic extract of binahong leaf fractionation to produce fractions of hexane (FHDB), chloroform (FKDB), ethyl acetate (FEADB), and ethanol (FEDB). Water fraction (FADB) was obtained from ethanolic leaf extract residues of binahong leaf extraction. Each fraction activity was tested topically twice daily on dorsal of test animals that created wounds using a punch biopsy 5 mm diameters. Grouping of test animals were divided into 13 groups with normal control group (non diabetes), negative control (diabetes + topical application of biocream®), positive control (diabetes + topical application of madecassol), and 10 diabetes groups with topical application of 5 kinds of binahong leaf fractions with each fractions consist of a concentrations of 5% and 10% with biocream® as a vehicle. Diabetic parameters measured include blood glucose levels (KGD) and weight lost percentage (PB%) in day 1 and 10 during a 10-day treatment. The results showed the influence of KGD in the condition of diabetes on wound healing rats diabetic ulcers which topically treated with binahong leaf fractions. FADB 10% has significant differences potention in wound healing process in diabetic rats macroscopically that accelerates wound contraction compared with negative and positive control groups (p<0,05).

Formulasi dan Evaluasi Gel Antioksidan Ekstrak Daun Bidara (Ziziphus jujuba Mill.) Trie Yuni Elfasyari; Lita Riastienanda Putri; Sawitri Wulandari
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 16 No. 02 Desember 2019
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Daun bidara memiliki kandungan fenolat dan flavonoid yang berkhasiat sebagai antioksidan. Penelitian ini bertujuan untuk memformulasikan ekstrak etanol daun bidara dalam bentuk sediaan gel serta uji aktivitas antioksidannya. Basis gel dibuat dengan variasi konsentrasi HPMC 3, 5, dan 7% dengan konsentrasi ekstrak 2,5% untuk setiap formula. Selanjutnya dilakukan evaluasi kestabilan gel selama 3 minggu. Aktivitas antioksidan diuji dengan metode DPPH. Hasil menunjukkan ekstrak etanol daun bidara dapat diformulasikan menjadi sediaan gel antioksidan dengan variasi basis HPMC 3 dan 5%, dimana sediaannya memiliki sifat fisik dan stabilitas yang baik, terbukti dengan tidak adanya perubahan organoleptis, pH, viskositas, dan daya sebar selama evaluasi. Gel ekstrak etanol daun bidara memiliki aktivitas antioksidan yang berbeda-beda berdasarkan variasi konsentrasi HPMC. Peningkatan konsentrasi HPMC menyebabkan perbedaan kemampuan pelepasan zat aktif yang ditunjukkan dengan persen inhibisi yang berbeda untuk F1, F2, and F3 yaitu masing-masing sebesar 52,55; 48,66; dan 32,88%.

Analisis Rhodamin B pada Lipstik Impor yang Beredar di Kota Batam secara Kromatografi Lapis Tipis dan Spektrofotometri UV-Vis Trie Yuni Elfasyari; Mutia Amelia Putri; Regina Andayani
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 17 No. 01 Juli 2020
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v17i1.5066

Zat warna rhodamin B adalah bahan pewarna yang dilarang penggunaannya dalam sediaan lipstik karena memiliki potensi karsinogenik dan merusak organ hati. Penelitian ini bertujuan untuk mengetahui secara kualitatif dan kuantitatif zat rhodamin B dalam sediaan lipstik impor yang beredar di Pasar Kota Batam. Metode yang digunakan adalah kromatografi lapis tipis untuk mengidentifikasi senyawa rhodamin B dengan menghitung nilai Rf dari fluoresensi bercak di bawah sinar ultraviolet. Penentuan kadar rhodamin B dilakukan dengan alat spektrofotometer UV-visibel dengan mengukur absorban pada panjang gelombang maksimum 548,5 nm. Konsentrasi larutan baku standar rhodamin B adalah 0,8; 1,2; 1,6; 2,0; dan 2,4 µg/mL. Didapatkan persamaan kurva y=0,0128+0,276x dengan r=0,9999. Hasil analisis kualitatif dari 15 merek sampel lipstik didapatkan dua merek lipstik yang teridentifikasi positif rhodamin B yaitu lipstik I dengan Rf 0,78 dan lipstik L dengan nilai Rf 0,77. Penentuan kadar rhodamin B dari masing-masing lipstik didapatkan kadar sebesar 73,225 µg/g pada lipstik I dan 92,61 µg/g pada lipstik L.

Sediaan Gel Ekstrak Etanol Daun Bidara (Ziziphus Mauritiana Lam.) Dengan Variasi Basis Gel HPMC: Sediaan Gel Ekstrak Etanol Daun Bidara (Ziziphus Mauritiana Lam.) Dengan Variasi Basis Gel HPMC Hidayati Hidayati; Sawitri Wulandari; Trie Yuni Elfasyari; Shinta Sari Dewi
Ahmar Metastasis Health Journal Vol. 2 No. 1 (2022): Ahmar Metastasis Health Journal
Publisher : Yayasan Ahmad Mansyur Nasirah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/amhj.v2i1.100

ABSTRACT Introduction: Bidara contains phenolic and flavonoid compounds that have many benefits including as antioxidants, anti-inflammatory, antimicrobial, antifungal, and inhibits the growth of tumor patients. This study aims to determine the effect of variations in HPMC concentration on the physical stability of the ethanol extract gel preparation of bidara leaves. This research uses laboratory experimental methods. The gel base was made with various HPMC concentrations of 0.5%, 1%, and 3% with an extract concentration of 1% for each formula. The gel stability was then evaluated for 3 weeks. The results showed that the ethanolic extract of bidara leaves can be formulated into gel preparations with variations in the HPMC base 0.5%, 1% and 3% where the preparation has good physical properties and stability, as evidenced by the absence of organoleptic changes, pH, dispersion, homogeneity, and viscosity during evaluation. The increase in HPMC concentration increased the viscosity and decreased the spreadability of the gel, but did not affect the organoleptic, homogeneity and pH of the gel. Data analysis using One Way ANOVA, the results of gel dispersion (p = 0.286) and gel viscosity (p = 0.128) showed that there was no significant difference in the physical properties of the gel. ABSTRAK Pendahuluan: Bidara mengandung senyawa fenolat dan flavonoid yang memiliki banyak manfaat diantaranya sebagai antioksidan, antiinflamasi, antimikroba, antifungi, serta menghambat adanya pertumbuhan pada penderita penyakit tumor. Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi HPMC terhadap stabilitas fisik sediaan gel ekstrak etanol daun bidara. Penelitian ini menggunakan metode eksperimental laboratorium. Basis gel dibuat dengan variasi konsentrasi HPMC 0,5%, 1%, dan 3% dengan konsentrasi ekstrak 1% untuk setiap formula. Selanjutnya dilakukan evaluasi kestabilan gel selama 3 minggu. Hasil penelitian menunjukkan ekstrak etanol daun bidara dapat diformulasikan menjadi sediaan gel dengan variasi basis HPMC 0,5%, 1% dan 3% dimana sediaannya memiliki sifat fisik dan stabilitas yang baik, terbukti dengan tidak adanya perubahan organoleptis, pH, daya sebar, homogenitas, dan viskositas selama evaluasi. Pada peningkatan konsentrasi HPMC meningkatkan viskositas dan menurunkan daya sebar gel, namun tidak mempengaruhi organoleptis, homogenitas dan pH gel. Analisis data menggunakan One Way ANOVA, hasil dari daya sebar gel (p=0,286) dan viskositas gel (p=0,128) ini menunjukkan tidak memberikan perbedaan yang bermakna terhadap sifat fisik gel.

HUBUNGAN KARAKTERISTIK PASIEN DIABETES MELITUS DAN TINGKAT KEPATUHAN MINUM OBAT DI RSUD EMBUNG FATIMAH KOTA BATAM Suci Fitriani Sammulia; Trie Yuni Elfasyari; M. Renaldy Pratama
JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Vol 5, No 2 (2020): Nopember 2020
Publisher : Prodi Kesehatan Masyarakat Fakultas Kesehatan Masyarakat UIN Sumatera Utara

Based on data from the World Health Organization (WHO), the death rate from diabetes will increase 2/3 times between 2008 and 2030. Non-compliance in carrying out its treatment can result in low blood sugar control and can cause complications. The purpose of this study was to determine the relationship between the characteristics of diabetes mellitus patients and the level of adherence to take medication at Embung Fatimah District Hospital in Batam. The design of this study was an observational study using a quantitative descriptive method using a cross sectional design performed on patients with Diabetes mellitus in embung Fatimah Regional Hospital Batam in January to March 2019. The instrument used in this study was the medication compliance questionnaire using MMAS-8 (Morisky Medication Adherence Scale) that has been validated. Data analysis using chi square statistics. Based on the results of the level of adherence of the questionnaire answers to 96 patients, namely, patients with low adherence as many as 20 people (20.8%), moderate adherence as many as 45 people (46.9%) and high adherence as many as 31 people (32.3%). The relationship of the level of adherence which includes age, sex, length of suffering, and concomitant diseases has a p value (0.753; 0.882; 0.908; and 0.952) which shows no significant relationship. While the relationship of the level of compliance with the level of education showed a significant relationship with the value of p = 0.001.

The BATANG KEMUMU (Colacasia gigantea cv) SEBAGAI BAHAN BAKU OBAT ALAMI ANTIBAKTERI DAN ANTIKANKER Hesti Marliza; Trie Yuni Elfasyari Elfasyari; Faziyana; Sarina Sembiring Milala
JURNAL KATALISATOR Vol. 6 No. 1 (2021): jurnal Katalisator Volume 6 No 1, 2021
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Kemumu (Colocasia gigantea cv) is a type of taro whose stems and leaves are edible. Kemumu belongs to the type of taro whose properties and phytochemical content, in particular, have not been widely reported. This study aims to determine the phytochemical content of kemumu stem as well as antibacterial bioactivity test and cytotoxic test (anticancer initial test) which can be used as raw materials for natural medicine. The stem is extracted using three types of solvents with different levels of polarity, n-Hexane, Ethyl acetate, and Ethanol. Antibacterial activity test uses agar diffusion method with some 20%, 40%, and 60% concentrations. Cytotoxic activity was tested by the Brine Shrimps Lethality Test (BSLT) method. Phytochemical test results are known that the kemumu extract contains secondary metabolites such as flavonoids, alkaloids, tannins, terpenoids, and steroids. The ethyl acetate extract contains flavonoids, tannins, terpenoids, and steroids. Antibacterial activity was found in ethyl acetate extract with a concentration of 40% with an inhibition zone of 17.5 mm. The highest LC50 value was also in the ethyl acetate extract of kemumu, which was 7.14 ppm. This value indicates a high level of toxicity so that ethyl acetate extract of kemumu acts as an antibacterial and anticancer.

Uji Aktivitas Antibakteri Ekstrak Selaput Umbi Bawang Putih (Allium Sativum) terhadap BakterI Staphylococcus aureus dan Escherichia coli Hesti Marliza; Rury Trisa Utami Rury; Fitri Ramadhani; Trie Yuni Elfasyari
Ahmar Metastasis Health Journal Vol. 3 No. 1 (2023): Ahmar Metastasis Health Journal
Publisher : Yayasan Ahmad Mansyur Nasirah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/amhj.v3i1.175

Rempah-rempah banyak digunakan sebagai pengobatan salah satu yang dimanfaatkan sebagai pengobatan adalah selaput umbi bawang putih (Allium sativum). Penelitian ini bertujuan untuk menentukan aktivitas ekstrak selaput umbi bawang putih terhadap bakteri Escherichia coli dan Staphylococcus aureus. Metode yang digunakan untuk ekstraksi adalah maserasi, untuk mengidentifikasi senyawa menggunakan skrining fitokimia dan uji aktivitas antibakteri menggunakan metode difusi cakram. Dalam ekstrak selaput umbi bawang putih mengandung senyawa alkaloid, flavonoid, saponin, fenolik, terpenoid. Ekstrak selaput umbi bawang putih (Allium sativum) memiliki aktivitas antibakteri terhadap Staphylococcus aureus dan Escherichia coli. Diameter ratarata zona hambat bakteri Escherichia coli paling besar dengan konsentrasi ekstrak kental 100% yaitu 8,5 mm dan pada Staphylococcus aureus dengan konsentrasi ekstrak kental 100% dengan zona hambat 8,7 mm. Berdasarkan hasil penelitian ini dapat disimpulkan selaput umbi bawang putih dapat menghambat pertumbuhan bakteri Escherichia coli dan Staphylococcus aureus dengan kekuatan sedang.

Penyuluhan Kesehatan Pemanfaatan Tanaman Obat Sebagai Peningkat Imunitas Masyarakat Kampung Karet, Nongsa Kota Batam Heldi Candra; Fifin Oktaviani; Trie Yuni Elfasyari; Hilda Muliana
Jurnal Pengabdian Masyarakat Bangsa Vol. 1 No. 5 (2023): Juli
Publisher : Amirul Bangun Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59837/jpmba.v1i5.96

Masyarakat di Indonesia sudah memanfaatkan Tanaman Obat Keluarga (TOGA) sebagai salah satu solusi masalah kesehatan di masyarakat, baik untuk pencegahan maupun pengobatan. Pemanfaatan tanaman obat semakin meningkat di masa pandemi COVID-19. Virus bisa masuk ke dalam tubuh ketika sistem kekebalan tubuh melemah. Beberapa Tanaman obat seperti jahe merah, temu lawak, kunyit, meniran, kencur, sambiloto memiliki manfaat sebagai pemicu kekebalan tubuh dan sebagai antioksidan yang dapat melawan radikal bebas. Kegiatan ini merupakan salah satu bentuk dari Penyuluhan kesehatan Masyarakat (PKM) yang bertujuan untuk meningkatkan pengetahuan masyarakat mengenai manfaat dari menanam tanaman obat keluarga (TOGA). Kegiatan yang dilakukan ialah pemberian edukasi serta pelatihan penanaman tanaman obat keluarga (TOGA) yang bisa ditanam di sekitar pekarangan rumah. Kegiatan ini dilaksanakan pada hari Kamis, 24 Maret 2022 di Kampung Karet Kecamatan Nongsa, Kota Batam. Setelah dilakukan kegiatan penyuluhan masyarakat desa kampung Karet dapat menggunakan tanaman obat sebagai pengobatan secara tradisional, memanfaatkannya sesuai khasiat dan kegunaannya dan mengetahui bagaimana cara menanam tanaman obat yang benar.

Co-Authors Citra Ariani Ersi Arviana Ihsan Faziyana Fifin Oktaviani Fitri Ramadhani Ghalib Syukrillah Syahputra Hanifah Karimatulhajj Heldi Candra Herlina, Merlin Hesti Marliza Hidayati Hidayati Hilda Muliana Kintoko, Kintoko Lita Riastienanda Putri M. Renaldy Pratama Maesaroh Adi Galih Sya Mevy Trisna Mutia Amelia Putri Nurkhasanah Nurkhasanah Nursyidah, Nursyidah Puspawan Hariadi Putra, Teguh Adiyas Regina Handayani Handayani, Regina Handayani Rofina Intan Sulistya Rury Trisa Utami Rury Sarina Sembiring Milala Sawitri Wulandari Sawitri Wulandari Shinta Cania Maiza Shinta Sari Dewi Shinta Sari Dewi Sri Hainil Suci Fitriani Sammulia Suci Santana Trisna, Mevy Yunisa Friscia Yusri Zulfisa

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