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Setyawan, Yuswanto
Universitas Ciputra
Religion Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Prominentia Medical Journal

 1 
BIOMARKER PADA LUPUS NEFRITIS Gisela Tania Irwanto; Yuswanto Setyawan
Bahasa Indonesia Vol 4 No 2 (2023): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v4i2.4559

Abstract

Lupus nephritis (LN) continues to be a leading cause of high morbidity and mortality rates in systemic lupus erythematosus (SLE) patients. Kidney biopsy remains the gold standard for diagnosing LN. Several biomarkers have been identified and evaluated, contributing to improvements in the management of LN patients. This literature review summarizes recent relevant literature on biomarkers for the diagnosis, monitoring, and prognosis of LN. These biomarkers are categorized based on their sample sources, namely serum and urine. Both sample sources show significant variations in biomarker data associated with disease activity and histological parameters of LN. Potential biomarker molecules include antibodies, cytokines, chemokines, and adhesion molecules. This literature review provides a general overview and serves as a reference for further research, particularly in advancing the understanding of LN biomarkers in Indonesia. Keywords: systemic lupus erythematosus (SLE), lupus nephritis (LN), biomarkers, serum, urin
VITAMIN D PADA ASMA BRONKIAL Setyawan, Yuswanto
Bahasa Indonesia Vol 5 No 1 (2024): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v5i1.4487

Abstract

Bronchial asthma is a lung disease characterized by reversible airway obstruction both spontaneously and with treatment, characterized by airways inflammation and hyperreactivity to various stimuli. Until now, the most effective treatment for asthma are corticosteroids and β-agonists, while the administration of prophylactic drugs is often less effective and often causes very disturbing side effects. Vitamin D is a group of fat-soluble secosteroids. Vitamin D has functions in modulating neuromuscular function, reducing inflammation and influencing the work of various genes that regulate cell proliferation, differentiation and apoptosis. Research shows that low levels of vitamin D are associated with increased allergy markers and asthma levels. Vitamin D is believed to play a role in asthma by inhibiting respiratory tract smooth muscle proliferation via hyperphosphorylation of the retinoblastoma protein and activation of checkpoint kinase 1 (Chk1). Vitamin D has recently been considered as a treatment for asthma.
Co-Authors Abdillah , Winda Adisyahputra, Vega Alfia, Nur Laili Areta Idarto Banjarnahor, Dharma PP Basudewa, I Nyoman Arhi Billy Daniel Messakh Christian Kutanggas, Rivo Deddi, Rhandy Bane Umbu Dongu Dharma PP Banjarnahor Erik Jaya Gunawan Gisela Tania Irwanto Harsa Sekarputri, Cempaka Hebert Adrianto Imelda Ritunga Indratiawati, Indratiawati Irwin Priyatna Kusumah Kusumah, Irwin Priyatna Kutanggas, Rivo Christian Kwando, Felicia Kwando, Feliciana Laurensia Budi, Stephanie Ledo, Naldi Lukas, Dwi Lily Ronald Pratama Adiwinoto Safira, Vita Sholihah, Puput Mar'atus Siahaan, Salmon Charles Siahaan, Salmon Charles P. T. Suharna, Anik Sulistio, Timothy Sultan, Dharma Sunur, Vincentius William Tannus, Ferdinand Aprianto Vincentia Maria Iriane Wargiati, Wargiati Wijaya , Wilson Gani Wijaya, Wilson Gani Wiyono, Mohamad