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All Journal HAYATI Journal of Biosciences Jurnal Ilmu Pertanian Indonesia Jurnal Teknologi Industri Pertanian Jurnal Veteriner CHEMISTRY PROGRESS BIOTROPIA - The Southeast Asian Journal of Tropical Biology Current Biochemistry ODONTO Dental Journal Pharmascience Dental Journal (Majalah Kedokteran Gigi) EnviroScienteae JURNAL PERTANIAN Journal of Science Innovare FITOFARMAKA: Jurnal Ilmiah Farmasi Jurnal Ilmiah Teknik Industri JSMARTech : Journal of Smart Bioprospecting and Technology Indonesian Journal of Applied Research (IJAR) Pharmaceutical And Biomedical Sciences Journal (PBSJ) Jurnal Pusat Inovasi Masyarakat JURNAL AGROINDUSTRI HALAL Odonto dental journal

Akhmad Endang Zainal Hasan

Department Of Biochemistry, Faculty Of Mathematics And Natural Sciences, IPB University, Bogor 16680, Indonesia

Author-ID : 1333325

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Social Sciences Transportation Veterinary

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Penerapan Ekstraksi Cair Tekanan Uap Tinggi Menggunakan Bahan Halal untuk Optimasi Antioksidan Akhmad Endang Zainal Hasan; Ike Yulia Wiendarlina; Witdiastuti Witdiastuti
JURNAL AGROINDUSTRI HALAL Vol. 8 No. 1 (2022): Jurnal Agroindustri Halal 8(1)
Publisher : Lembaga Riset dan Pengabdian Kepada Masyarakat Universitas Djuanda Bogor

Soursop is a plant that is used as traditional medicine. Antioxidants are compounds that are able to delay, slow down, or inhibit oxidation reactions. This study aims to determine the effect of variations in extraction time and the comparison of variations in the amount of simplicia with aquadest solvent on the high pressure extraction method on antioxidant activity. The study made 13 treatments using the Response Surface Methodology (RSM) design with the fit of the Central Composite Design (CCD) model. The results showed that from the 13 treatments, the extraction time had an effect on the percent yield with the equation Y = -51.9692 + 24.2030 X1 + 1.2984 X2. The extraction time (X1) has a value greater than the ratio of simplicia powder to the volume of distilled water (X2) as well as the IC50 value as shown in the equation Y = 171,983 + 13,828 X1 – 4,110 X2. Extraction time (X1) has a greater value when compared to simplicia with aquadest solvent volume (X2). The results of the analysis of the percentage of extract yield and the optimal IC50 value using RSM analysis were thought to have an extraction time of 6.3 minutes and the ratio of simplicia powder to the volume of aquadest solvent was 1:61,2. The results of the antioxidant activity obtained that the optimal IC50 value was estimated at 4.3 minutes of extraction time and the ratio of simplicia powder to the volume of aquadest solvent was 1:78.2.

Uji Penghambatan α-Glukosidase dari Kombinasi Ekstrak Kunyit, Teh Hitam dan Jahe: The α-Glucosidase Inhibition Test from a Combination of Turmeric Extract, Black Tea, and Ginger Akhmad Endang Zainal Hasan; Dimas Andrianto; Rara Annisaur Rosyidah
JURNAL AGROINDUSTRI HALAL Vol. 8 No. 1 (2022): Jurnal Agroindustri Halal 8(1)
Publisher : Lembaga Riset dan Pengabdian Kepada Masyarakat Universitas Djuanda Bogor

Traditional medicines that can be used as α-glucosidase inhibitors are turmeric (Curcuma longa L.), black tea (Camellia sinensi L), and ginger (Zingiber officinale). It is necessary to research the use of a combination of tea, turmeric, and ginger in inhibiting the α -glucosidase enzyme. This study aims to determine the optimal combination of extracts of turmeric, black tea, and ginger in inhibiting the α-glucosidase enzyme. The research carried out was the measurement of IC50 values for the inhibition of α-glucosidase of each extract, and the inhibition of the enzyme α-glucosidase in combination. The results of the test of ethanol extract of turmeric, ginger and black tea water extract obtained the inhibition value of α-glucosidase with IC50 values of 9.48±0.05 g/mL, 66.64±0.44 g/mL and 9.52±0.25, respectively. F7 is a combination of turmeric, ginger and black tea which produces the highest α-glucosidase inhibition, which is 67.86±0.93%.

Antioxidant Activity and Total Flavonoid Propolis Stingless Bee Hasan, Akhmad Endang Zainal; Safira, Ukhradiya Maharaniq; Purnamasari, Anita; Wardatun, Sri
JURNAL AGROINDUSTRI HALAL Vol. 9 No. 2 (2023): Jurnal Agroindustri Halal 9(2)
Publisher : Universitas Djuanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30997/jah.v9i2.6818

Propolis from Indonesia contains secondary metabolites which include flavonoids and other organic compounds. The ethanol extract of 70% propolis Trigona spp from Pandeglang can be used as an antibacterial compound. The purpose of this study was to examine the toxicity of the propolis and nanopropolis with an LC50 value, test the antioxidant activity with an IC50 value, and determine the total flavonoid content. LC50 was determined by the BSLT method on Artemia salina Leach larvae. The antioxidant activity was tested using the DPPH method (1,1 diphenyl-2-picrylhydrazil), and the determination of flavonoid content was carried out with aluminum chloride. The results showed that the LC50 value of propolis was 16.010 ppm, and for 20% nanopropolis was 18.689 ppm. Antioxidant activity obtained IC50 value for propolis is 95.54593 ppm, for 20% nanopropolis is 527.7939 ppm. The total flavonoid content of the propolis was 2.1123%, and the total flavonoid content for the nanopropolis equivalent extract was 1.5293%.

Co-Authors Agus Setiyono Aisyah Aisyah Alfina Zalfa Suryono Amalia, Lathifah Antonius Anre Sianturi Aris Tri Wahyudi Armando Balses Ishimora Aton Yulianto Aziz Syamsul Huda Aziz Syamsul Huda Bayu Sandi Bina Lohita Sari Bram Kusbiantoro Bustomi - Bustomi Chintia Ayu Puspita Cokro, Ingrid Aurelia Genacia Dadan Rohdiana Deviyanti Pratiwi Dewi Priandini Dewi Priandini, Dewi DIMAS ANDRIANTO Djarot Sasongko Hami Seno Djumali Mangunwidjaja Dwi Rofifah Putri Jania E. Mulyati Effend Effend, E. Mulyati Ekowati Handharyani Eny Ida Riyanti Eny Ida Riyanti Erlank Bagjavicenna Faisal Rahman Handayani, Septa Fitri Hasanah, Rima Nidaul Hasim Hasim Hasim Hasim Heddy Julistiono Heddy Julistiono Henry Adiprabowo, I Made Artika, Heny Herawati Huda, Aziz Syamsul Husnawati, . I MADE ARTIKA Ika Mulawati Purwanti Noviana Ike Agustiani Ike Yulia Wiendarlina Ilham Gilang Cahya Ahmada Indradewa, Rhian Ingrid Aurelia Genacia Cokro Isra Janatiningrum Karichsa Hariana Khaswar Syamsu Kristina Mulia LAKSMI AMBARSARI Luthfi Ramadhani, Dhani Mega Safithri Miko Afrian Moerfiah Mona . Muhamad Alvin Adriyan Muhammad Zulkifli Mutholaah Nashrianto, Husain Ni Putu Ratna Ayu Krishanti Noli Novidahlia Novi Fajar Utami Novia Juhaeni, Rani Nurliani Bermawie Olive Wisepti Pratama Ono Suparno Purnamasari, Anita Purnomo Purnomo Putri Ramadhanty Rafida Nisa Maghfiroh Ranady Perwira Nuruzzaman Rara Annisaur Rosyidah Rini Kurniasih, Rini Rosyidah, Rara Annisaur Safira, Ukhradiya Maharaniq Salim, Richentya Feiby Sandi, Bayu Sekar Winahyu Ariadini Sharon Aurellia Siti Magfiroh Siti Sholekha Siti Wachidatun Zulaikha Siwi Putri Andini Sri Budiarti Sri Wahyuni Sri Wardatun SURYANI Suryani Suryani Syaeful Abidin Syifa Khaerani Tansza Setiana Putri Titi Candra Sunarti Tommy Abrar Tri Joko Santoso Ulya Utami Vetnizah Juniantito Winahyu Ariadini, Sekar Witdiastuti Witdiastuti Zainal Alim Mas'ud

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