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Edukasi Hidup Sehat bagi Siswa SDN 93 Kendari bersama Puskesmas Mokoau Wahyuni, Wahyuni; Fitrawan, La Ode Muhammad; Pascayantri, Asniar; Mutmainah A., Nur; Wijaya, Rawiyatin; Hartinah, Sitti; Aprilia, Yuyun; Veragita, Elsa; Fathonah, Annisya Syamsah Hizyar; MR, Muhammad Fauzan.; Jalil, Intan Permatasari
Jurnal Pengabdian Masyarakat (ABDIRA) Vol 6, No 1 (2026): Abdira
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdira.v6i1.1351

Abstract

Young children are highly sensitive to their surroundings and tend to imitate the behavior of the adults around them. Therefore, education and the habit of clean and healthy living from an early age are very important in forming positive habits and preventing disease in the future. This activity was carried out in collaboration with the Mokoau Community Health Center through counseling students on how to live healthily to prevent intestinal worms, diarrhea, and infectious diseases at school and at home, with the help of leaflets. The results of this activity showed an increase in students' knowledge about the prevention of intestinal worms, diarrhea, respiratory infections, and measles. They understood that intestinal worms can be transmitted through dirty soil or food and the importance of maintaining personal hygiene, such as washing hands and wearing footwear. This improvement was evident during the discussion session, when students were able to answer questions correctly and explain how to prevent these diseases. In addition, students were also able to practice proper hand washing and apply coughing and sneezing etiquette.
Metabolite Profiling and Anti-Inflammatory Potential of East Kolaka Forest Honey: Targeting Protein Denaturation through GC-MS/MS Characterization Hariana, Hariana; Wahyuni, Wahyuni; Irnawati, Irnawati; Fitrawan, La Ode Muhammad; Munasari, Dian; Yodha, Agung Wibawa Mahatva; Purnama, La Ode Muhammad Julian; Fristiohady, Adryan
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 2 (2025): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i2.860

Abstract

Forest honey is a natural product produced by wild bees that gather nectar from various types of flowers, creating a unique chemical composition influenced by the biodiversity of the surrounding environment. This honey contains bioactive compounds such as phenolics, flavonoids, terpenoids, and volatile substances that contribute to its pharmacological properties, particularly as an anti-inflammatory agent. This study aimed to identify bioactive compounds in forest honey from East Kolaka using Gas Chromatography-Mass Spectrometry (GC-MS) and to evaluate its anti-inflammatory activity through in vitro assays, including red blood cell (RBC) membrane stabilization, protein denaturation inhibition, and nitric oxide (NO) production inhibition. GC-MS analysis revealed several volatile compounds with antioxidant, antimicrobial, and anti-inflammatory properties. The RBC membrane stabilization assay showed increased membrane stability as honey concentration increased, reaching 92.55% at 100 mg/L compared to 97.00% for sodium diclofenac. In the protein denaturation assay, East Kolaka forest honey had an IC?? value of 12.70?±?0.02?mg/L, categorized as moderate, while the NO inhibition assay recorded an IC?? of 2.97?±?1.34?mg/L, indicating strong activity, approaching that of vitamin C (1.07?±?0.39?mg/L). Statistical tests showed significant differences (p < 0.05) in all tested parameters compared to positive controls. These results support the potential of East Kolaka forest honey as a natural anti-inflammatory agent through mechanisms involving membrane stabilization, protein protection, and nitric oxide suppression.