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Journal : Jurnal Buana Farma

EVALUASI RASIONALITAS PENGGUNAAN ANTIBIOTIK PASIEN PNEUMONIA DI RS TIPE B KOTA BOGOR Septiani, Wulan; Rosiana, Rosiana; Dewi, Masita Sari; Marselina, Marselina
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1509

Abstract

Pneumonia remains one of the leading causes of morbidity and mortality worldwide. Inappropriate use of antibiotics can increase the risk of bacterial resistance. Rationality evaluation is essential to ensure appropriate selection, dosage, and duration of therapy. This study aimed to describe the characteristics of pneumonia patients, antibiotic prescribing patterns, and their rational use in the inpatient ward of Type B Hospital in Bogor City in 2024. A retrospective descriptive design was employed using medical records of 83 pneumonia patients from January to December 2024. Data were analyzed descriptively, and rationality was assessed using the Gyssens method based on the Ministry of Health Regulation No. 28 of 2021. The results showed that most patients were aged ≥60 years (41.0%) and male (51.8%). The most commonly used antibiotics were ceftriaxone (57.9%) and levofloxacin (20.0%). Category 0 (appropriate) accounted for 55.6%, while 44.4% were inappropriate, mainly IVa (23.3%) and IIIb (10.0%). Conclusion: Improving rationality requires regular evaluation, clinical pathways, and antimicrobial stewardship programs.
HUBUNGAN TINGKAT KEPATUHAN TERAPI ANTIHIPERTENSI DENGAN RISIKO KARDIOVASKULAR DI PUSKESMAS CIKARANG Anggita, Rahmi; Marselina; Adwisastra, Nuzul Gyanata; Dewi, Masita Sari
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1511

Abstract

Hypertension is a major risk factor for cardiovascular disease. However, evidence regarding the association between adherence to antihypertensive therapy and cardiovascular risk remains inconsistent, particularly in primary care settings. This study was conducted at Cikarang Community Health Center, where hypertension is among the top ten most prevalent diseases. The objective was to determine the relationship between adherence to antihypertensive therapy and cardiovascular risk. A cross-sectional analytical study was conducted on 85 purposively selected hypertensive patients. Adherence was assessed using MARS-5 and Medication Possession Ratio (MPR), while cardiovascular risk was calculated with the ASCVD score. Data were analyzed using Chi-Square, linearity test, and Odds Ratio. Results showed that most patients were adherent (MARS-5 = 91.8%; MPR = 76.5%) and had low cardiovascular risk (64.7%). There was a significant association between adherence and cardiovascular risk (MARS-5 p=0.041; MPR p=0.049). Adherent patients were more likely to have lower cardiovascular risk. In conclusion, higher adherence is associated with lower cardiovascular risk. Continuous education and routine monitoring are essential to maintain adherence and prevent complications.
HUBUNGAN TINGKAT KEPATUHAN DAN PENGETAHUAN PASIEN TERHADAP PENGOBATAN TUBERKULOSIS PARU DI PUSKESMAS MEKARMUKTI TAHUN 2025 Evellia Priastuti; Dewi, Masita Sari; Adiwisastra, Nuzul Gyanata; Marselina, Marselina
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1506

Abstract

Tuberculosis (TB) is a global and national public health problem, as well as an important indicator of achieving the Sustainable Development Goals (SDGs). Indonesia continues to face a high burden of tuberculosis, ranking second after India with millions of cases each year. Treatment success rates have not yet reached the national target, while West Java, including Bekasi Regency, records the highest cases. At Mekarmukti Health Center, in 2016 there were 81 new smear-positive pulmonary TB cases and 16 old cases, with a total of 97 patients, highlighting the importance of sustainable control at primary health services. This study aims to analyze the relationship between knowledge and treatment adherence among TB patients at Mekarmukti Health Center. This quantitative research employed an observational method with a total sampling technique involving 95 respondents. The instrument used was a questionnaire, and data analysis was conducted using the chi-square test. The results showed a relationship between age and knowledge (p=0.000), education and knowledge (p=0.041), as well as treatment category and knowledge (p=0.028). Age was also associated with adherence (p=0.002). However, knowledge was not significantly associated with adherence (p=0.337).
HUBUNGAN PENGETAHUAN PASIEN DENGAN KEPATUHAN ANTIHIPERTENSI DAN LUARAN KLINIS Dewi, Antih Puspita; Marselina, Marselina; Adiwisastra, Nuzul Gyanata; Dewi, Masita Sari
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1521

Abstract

Hypertension is a highly prevalent chronic disease in Indonesia. Patients’ knowledge is considered a key factor in improving adherence, but its association with blood pressure control remains inconsistent. To evaluate the relationship between patients’ knowledge, antihypertensive medication adherence, and blood pressure control among hypertensive patients at Cikarang Primary Health Center. This cross-sectional analytic study involved 51 hypertensive patients who had received therapy for at least three months. Instruments included the Hypertension Knowledge-Level Scale (HK-LS) to assess knowledge, the Morisky Medication Adherence Scale (MMAS-8) to measure adherence, and medical records to determine blood pressure control. Data were analyzed using Chi-Square and Pearson correlation tests. Most respondents demonstrated high knowledge (70.59%), yet nearly half showed low adherence (47.06%). Knowledge was significantly associated with adherence (p=0.039), while no significant relationship was found between knowledge and blood pressure control (p=0.733). Higher knowledge improves medication adherence but does not necessarily lead to optimal blood pressure control. Comprehensive strategies beyond knowledge enhancement are needed for effective hypertension management.
HUBUNGAN TINGKAT PENGETAHUAN DENGAN KEPATUHAN MINUM OBAT DAN LUARAN KLINIS PASIEN HIPERTENSI DI PUSKESMAS SETU 1 KABUPATEN BEKASI TAHUN 2025 Putri, Intan Auliya; Marselina, Marselina; Dewi, Masita Sari; Adiwisastra, Nuzul Gyanata
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1534

Abstract

Hypertension is a non-communicable disease that is a major health problem in Indonesia, especially in industrial areas such as Bekasi Regency. Patient knowledge of hypertension affects adherence to treatment and the success of therapy as measured by clinical outcomes in the form of blood pressure achievement. This study aims to determine the relationship between the level of knowledge with medication adherence and clinical outcomes in hypertensive patients at the Setu 1 Community Health Center in Bekasi Regency. This study used a quantitative design with a cross-sectional approach, involving 91 respondents selected using a purposive sampling technique. The instruments used included the HK-LS questionnaire to assess knowledge, the MMAS-8 for adherence, and medical record data for clinical outcomes. The analysis results showed a significant relationship between the level of knowledge with medication adherence (p = 0.009) and clinical outcomes of blood pressure (p = 0.003). It can be concluded that the higher the patient's level of knowledge, the higher the adherence to treatment and the success of achieving target blood pressure.
TINGKAT PENGETAHUAN DAN KEPATUHAN TERHADAP KUALITAS HIDUP PASIEN TUBERKULOSIS DI PUSKESMAS CIKARANG Damayanti, Nanda; Dewi, Masita Sari; Adiwisastra, Nuzul Gyanata; Rosiana, Rosiana
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1542

Abstract

Tuberculosis (TB) remains a major public health problem in Indonesia, including Bekasi Regency, which has a high disease burden. A decline in quality of life is commonly experienced by TB patients due to clinical symptoms, social stigma, and adverse drug effects. Although patient knowledge and treatment adherence are widely believed to influence therapeutic outcomes, evidence regarding their impact on quality of life remains inconsistent and limited, particularly in the Cikarang region. This study aimed to examine the relationship between knowledge level and treatment adherence with the quality of life of pulmonary tuberculosis patients at Puskesmas Cikarang Utara. A cross-sectional design was employed involving 93 outpatient pulmonary TB patients who met the inclusion criteria, including age 17–65 years, undergoing category I/II therapy, able to communicate, and willing to participate, as well as exclusion criteria of having significant comorbid conditions. Participants were selected using purposive sampling. Data were collected using a structured knowledge questionnaire, the Morisky Medication Adherence Scale (MMAS-8), and the Short Form-36 (SF-36). Statistical analysis was performed using the Chi-Square test. The majority of respondents demonstrated good knowledge (86%), moderate to high treatment adherence (86%), and a high quality of life (55.9%). Chi-Square analysis indicated no significant association between knowledge level and quality of life (p = 0.468), nor between treatment adherence and quality of life (p = 0.962). These findings suggest that knowledge and adherence alone are insufficient determinants of quality of life among pulmonary TB patients. Therefore, improving patients’ quality of life requires comprehensive interventions. Beyond treatment adherence.
HUBUNGAN TINGKAT PENGETAHUAN DAN KEPATUHAN DENGAN KEBERHASILAN PENGOBATAN PASIEN TUBERKULOSIS DI PUSKESMAS TELAGA MURNI, CIKARANG Salamah, Hanifah Ikka; Dewi, Masita Sari; Adiwisastra, Nuzul Gyanata; Marselina, Marselina
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1549

Abstract

Tuberculosis (TB) remains a public health problem in Indonesia, with treatment success rates that have not yet reached national targets, partly influenced by patient behavioral factors. Patient knowledge and medication adherence are considered important determinants of TB treatment outcomes. This study aimed to analyze the relationship between patients’ knowledge level and medication adherence with tuberculosis treatment success at Telaga Murni Community Health Center, West Cikarang District. This quantitative study employed a correlational analytical design using a cross-sectional approach. The study sample consisted of 80 adult pulmonary TB patients selected through total sampling. Data were collected through structured interviews using a knowledge questionnaire and the Morisky Medication Adherence Scale-8 (MMAS-8), as well as medical record reviews to assess treatment success. Data were analyzed using univariate and bivariate analysis with the Chi-square test. The majority of respondents were female (58.7%), aged 17–25 years (35%), had senior high school education (50%), and were unemployed (51.2%). Most respondents received treatment observer (PMO) assistance (58.8%), were in the advanced treatment phase (58.7%), and were classified under treatment category I (97.5%). Good knowledge levels were identified in 90% of respondents, while low medication adherence was observed in 85%. Treatment success was achieved in 12.5% of respondents. Chi-square analysis showed no statistically significant relationship between knowledge level and treatment success (p = 0.827), nor between medication adherence and treatment success (p = 0.365). In conclusion, patient knowledge level and medication adherence were not significantly associated with tuberculosis treatment success, suggesting the need for broader multidisciplinary intervention strategies.