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Role of Gamma-Glutamyl Transferase, High Sensitivity C Reactive Protein and Apolipoprotein B as A Marker of Disease Severity in Psoriasis Shofiyah, Laily; Ardyanto, Tonang Dwi; Prabowo, Nurhasan Agung; Aprilningsih, Hendrastutik; Myrtha, Risalina; Kuncorowati, Niken Dyah Aryani; Suwandono, Adji; Nugroho, Novianto Adi; Sari, Maria Galuh Kamenyangan; Dyanneza, Frieska
Gema Lingkungan Kesehatan Vol. 23 No. 3 (2025): Gema Lingkungan Kesehatan
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v23i3.285

Abstract

Psoriasis can develop into systemic psoriasis, which primarily affects the liver, bile ducts, and cardiovascular system. Assessing the severity of psoriasis was crucial for determining treatment and cardiovascular disease risk. The aim of this study was to determine the role of Gamma-Glutamyl Transferase (GGT), High Sensitivity C-Reactive Protein (HS-CRP), and apolipoprotein B (APO B) in assessing the severity of psoriasis. Methods: This study was a cross-sectional, observational analytic study. A total of 33 psoriasis patients were tested for GGT, HS-CRP, APO B levels, and the Psoriasis Area and Severity Index (PASI) score. Results: The average GGT level was 70.75±56.47 u/L, the average HS-CRP level was 0.91±1.03 mg/L, the average APO B level was 110.09±26.47 mg/dL, and the average PASI score was 11.70±4.54. 12.1% of patients had mild psoriasis, 51.5% had moderate psoriasis, and 36.4% had severe psoriasis. There was a positive and strong correlation between GGT and PASI score, HS-CRP and PASI score, and APO B and PASI score. The multivariate correlation between GGT, HS-CRP, and APO B with PASI score had a value of R = 0.874, F = 31.145, p = <0.001. Conclusion: The multivariate correlation between GGT, HS-CRP, and APO B with PASI scores shows a positive and strong correlation, thus it useful for assessing the severity of psoriasis and evaluating the likelihood of cardiovascular disease.
ST-Depresi pada Infark Miokard Akut dengan Elevasi Segmen ST–Pentingnya Perubahan Resiprokal pada Elevasi Segmen ST yang Minimal Myrtha, Risalina; Wijayanto, Matthew Aldo; Putri, Desy Puspa; Hermawati, Berty Denny
Jurnal Biomedika dan Kesehatan Vol 7 No 3 (2024)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2024.v7.339-344

Abstract

Coronary artery disease remains the leading cause of mortality globally. Management of ST-elevation myocardial infarction (STEMI) starts from the point of first medical contact. Time delay to treatment influences the mortality in STEMI patients. The aim of this study is to underline the importance of reciprocal ECG changes in helping diagnosis STEMI with subtle ST elevation. We present an obese and hypertensive male patient with atypical symptoms of MI and was diagnosed as peptic ulcer. The ECG showed subtle ST elevation in inferior ECG leads and reciprocal changes in I and aVL. Highly sensitive troponin was elevated. Serial ECG showed evolution, thus revealed acute inferior MI. Successful percutaneous coronary intervention was performed. ECG is one of the most important diagnosis tools in STEMI and a cornerstone to direct the decision to immediate reperfusion therapy. Minimal ST-elevation often leads to inappropriate diagnosis, thus delayed the time to reperfusion. A study shows that 11-23% of STEMI do not reach the cutoff for accepted ECG criteria. In a study of infarctions with minimal ST-elevation, reciprocal changes are reported in 58% of all cases. Reciprocal ECG changes is extremely useful to help identifying STEMI in the absence of obvious ST-elevation on ECG
Implementation of an Education and Early Detection Program to Reduce the Risk of Occupational Lung Disease in Furniture Craftsmen in Sambirembe Village Ardyanto, Tonang Dwi; Myrtha, Risalina; Prabowo, Nurhasan Agung; Apriningsih , Hendrastutik; Dyanneza, Frieska; Kuncorowati, Niken Dyah Aryani; Nugroho, Novianto Adi; Suwandono, Adji; Sari, Maria Galuh Kamenyangan; Shofiyah, Laily
Sebatik Vol. 29 No. 2 (2025): December 2025
Publisher : STMIK Widya Cipta Dharma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46984/sebatik.v29i2.2640

Abstract

Furniture industry workers in Sambirembe Village, Sragen, face significant health risks from exposure to wood dust, particularly an increased risk of Chronic Obstructive Pulmonary Disease (COPD). This research is prompted by the low awareness among workers regarding these risks and the minimal use of personal protective equipment (PPE). The objective of this program was to increase workers' and business owners' knowledge of lung health, promote early detection of COPD, and encourage the adoption of safer work practices. The method employed was an intervention that included health education and lung function screening via questionnaires and spirometry. The results revealed a critical knowledge gap, where over 85% of workers had never heard of COPD, even though 70% of them reported experiencing respiratory symptoms. Furthermore, over 90% of workers admitted to rarely using masks. The intervention, which combined education with personalized spirometry data feedback, proved effective in increasing worker awareness of tangible health risks. In conclusion, the education-based and health-screening intervention program successfully raised furniture workers' understanding of COPD risks. An approach that integrates information with personal medical evidence is crucial for promoting behavioural change in high-risk work environments.
The Importance of Hyperthyroid Screening in Acute Decompensated Heart Failure with Persistent Tachycardia Despite Optimal Decongestion: A Case Report Myrtha, Risalina; Wijayanto, Matthew Aldo; Prabowo, Nurhasan Agung
Jurnal Kardiologi Indonesia Vol 46 No 4 (2025): October - December, 2025
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.2006

Abstract

In “The Importance of Hyperthyroid Screening in Acute Decompensated Heart Failure with Persistent Tachycardia Despite Optimal Decongestion: A Case Report” (Indonesian Journal of Cardiology, 43(3), 123-9. https://doi.org/10.30701/ijc.1328), there is an error noted. An error has been found in the PDF version of this article. The DOI printed in the PDF is incorrect. The correct DOI is https://doi.org/10.30701/ijc.1328. The error occurs only in the PDF; the DOI listed in the article metadata is already correct.The publisher apologizes for any inconvenience caused by this error.DOI of original article: https://doi.org/10.30701/ijc.1328