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All Journal Global Medical and Health Communication WARTA Indonesian Journal of Cardiology Sebatik Journal of Information Technology and Computer Engineering Jurnal Biomedika dan Kesehatan Jurnal Dharma Bhakti Ekuitas Narra J Cermin Dunia Kedokteran Gema Lingkungan Kesehatan
Myrtha, Risalina
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Role of Gamma-Glutamyl Transferase, High Sensitivity C Reactive Protein and Apolipoprotein B as A Marker of Disease Severity in Psoriasis Shofiyah, Laily; Ardyanto, Tonang Dwi; Prabowo, Nurhasan Agung; Aprilningsih, Hendrastutik; Myrtha, Risalina; Kuncorowati, Niken Dyah Aryani; Suwandono, Adji; Nugroho, Novianto Adi; Sari, Maria Galuh Kamenyangan; Dyanneza, Frieska
Gema Lingkungan Kesehatan Vol. 23 No. 3 (2025): Gema Lingkungan Kesehatan
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v23i3.285

Abstract

Psoriasis can develop into systemic psoriasis, which primarily affects the liver, bile ducts, and cardiovascular system. Assessing the severity of psoriasis was crucial for determining treatment and cardiovascular disease risk. The aim of this study was to determine the role of Gamma-Glutamyl Transferase (GGT), High Sensitivity C-Reactive Protein (HS-CRP), and apolipoprotein B (APO B) in assessing the severity of psoriasis. Methods: This study was a cross-sectional, observational analytic study. A total of 33 psoriasis patients were tested for GGT, HS-CRP, APO B levels, and the Psoriasis Area and Severity Index (PASI) score. Results: The average GGT level was 70.75±56.47 u/L, the average HS-CRP level was 0.91±1.03 mg/L, the average APO B level was 110.09±26.47 mg/dL, and the average PASI score was 11.70±4.54. 12.1% of patients had mild psoriasis, 51.5% had moderate psoriasis, and 36.4% had severe psoriasis. There was a positive and strong correlation between GGT and PASI score, HS-CRP and PASI score, and APO B and PASI score. The multivariate correlation between GGT, HS-CRP, and APO B with PASI score had a value of R = 0.874, F = 31.145, p = <0.001. Conclusion: The multivariate correlation between GGT, HS-CRP, and APO B with PASI scores shows a positive and strong correlation, thus it useful for assessing the severity of psoriasis and evaluating the likelihood of cardiovascular disease.
ST-Depresi pada Infark Miokard Akut dengan Elevasi Segmen ST–Pentingnya Perubahan Resiprokal pada Elevasi Segmen ST yang Minimal Myrtha, Risalina; Wijayanto, Matthew Aldo; Putri, Desy Puspa; Hermawati, Berty Denny
Jurnal Biomedika dan Kesehatan Vol 7 No 3 (2024)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2024.v7.339-344

Abstract

Coronary artery disease remains the leading cause of mortality globally. Management of ST-elevation myocardial infarction (STEMI) starts from the point of first medical contact. Time delay to treatment influences the mortality in STEMI patients. The aim of this study is to underline the importance of reciprocal ECG changes in helping diagnosis STEMI with subtle ST elevation. We present an obese and hypertensive male patient with atypical symptoms of MI and was diagnosed as peptic ulcer. The ECG showed subtle ST elevation in inferior ECG leads and reciprocal changes in I and aVL. Highly sensitive troponin was elevated. Serial ECG showed evolution, thus revealed acute inferior MI. Successful percutaneous coronary intervention was performed. ECG is one of the most important diagnosis tools in STEMI and a cornerstone to direct the decision to immediate reperfusion therapy. Minimal ST-elevation often leads to inappropriate diagnosis, thus delayed the time to reperfusion. A study shows that 11-23% of STEMI do not reach the cutoff for accepted ECG criteria. In a study of infarctions with minimal ST-elevation, reciprocal changes are reported in 58% of all cases. Reciprocal ECG changes is extremely useful to help identifying STEMI in the absence of obvious ST-elevation on ECG
Co-Authors Adji Suwandono Anindita, Brigitta Devi Aprilningsih, Hendrastutik Apriningsih, Apriningsih Apriningsih Apriningsih, Hendrastutik Artika Ramadhani Ayusari, Amelya Augusthina Budiono, Enrico A. Dewi, Herlina K. Dyanneza, Frieska Fadly, Ainal Febri Liantoni, Febri Gautama, Coana S. Hamka, Muhammad Farid Hermawati, Berty D. Hermawati, Berty Denny Ilyas, Muhana F. Irnizarifka Kuncorowati, Niken Dyah Aryani Maria Galuh Kamenyangan Sari, Maria Galuh Kamenyangan Modesty, Kyra Murasmita, Alamanda Nugroho, Novianto Adi Prabowo, Nurhasan A. Prabowo, Nurhasan Agung Priamas, Adigama Putranto, Wachid Putri, Desy P. Putri, Desy Puspa Rahma, Annisa A. Rahman, Awalil R. K. Ratna Kusumawati Reviono Reviono Shofiyah, Laily Sukmagautama, Coana Tonang Dwi Ardyanto Tristan, Christopher D. Wijayanto, Matthew A. Wijayanto, Matthew Aldo Wulandari, Evi L.