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All Journal Global Medical and Health Communication WARTA Smart Medical Journal Indonesian Journal of Cardiology Sebatik Journal of Information Technology and Computer Engineering Jurnal Biomedika dan Kesehatan Jurnal Dharma Bhakti Ekuitas Narra J Cermin Dunia Kedokteran Smart Society Empowerment Journal Gema Lingkungan Kesehatan
Myrtha, Risalina
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Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Role of Gamma-Glutamyl Transferase, High Sensitivity C Reactive Protein and Apolipoprotein B as A Marker of Disease Severity in Psoriasis Shofiyah, Laily; Ardyanto, Tonang Dwi; Prabowo, Nurhasan Agung; Aprilningsih, Hendrastutik; Myrtha, Risalina; Kuncorowati, Niken Dyah Aryani; Suwandono, Adji; Nugroho, Novianto Adi; Sari, Maria Galuh Kamenyangan; Dyanneza, Frieska
Gema Lingkungan Kesehatan Vol. 23 No. 3 (2025): Gema Lingkungan Kesehatan
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v23i3.285

Abstract

Psoriasis can develop into systemic psoriasis, which primarily affects the liver, bile ducts, and cardiovascular system. Assessing the severity of psoriasis was crucial for determining treatment and cardiovascular disease risk. The aim of this study was to determine the role of Gamma-Glutamyl Transferase (GGT), High Sensitivity C-Reactive Protein (HS-CRP), and apolipoprotein B (APO B) in assessing the severity of psoriasis. Methods: This study was a cross-sectional, observational analytic study. A total of 33 psoriasis patients were tested for GGT, HS-CRP, APO B levels, and the Psoriasis Area and Severity Index (PASI) score. Results: The average GGT level was 70.75±56.47 u/L, the average HS-CRP level was 0.91±1.03 mg/L, the average APO B level was 110.09±26.47 mg/dL, and the average PASI score was 11.70±4.54. 12.1% of patients had mild psoriasis, 51.5% had moderate psoriasis, and 36.4% had severe psoriasis. There was a positive and strong correlation between GGT and PASI score, HS-CRP and PASI score, and APO B and PASI score. The multivariate correlation between GGT, HS-CRP, and APO B with PASI score had a value of R = 0.874, F = 31.145, p = <0.001. Conclusion: The multivariate correlation between GGT, HS-CRP, and APO B with PASI scores shows a positive and strong correlation, thus it useful for assessing the severity of psoriasis and evaluating the likelihood of cardiovascular disease.
ST-Depresi pada Infark Miokard Akut dengan Elevasi Segmen ST–Pentingnya Perubahan Resiprokal pada Elevasi Segmen ST yang Minimal Myrtha, Risalina; Wijayanto, Matthew Aldo; Putri, Desy Puspa; Hermawati, Berty Denny
Jurnal Biomedika dan Kesehatan Vol 7 No 3 (2024)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2024.v7.339-344

Abstract

Coronary artery disease remains the leading cause of mortality globally. Management of ST-elevation myocardial infarction (STEMI) starts from the point of first medical contact. Time delay to treatment influences the mortality in STEMI patients. The aim of this study is to underline the importance of reciprocal ECG changes in helping diagnosis STEMI with subtle ST elevation. We present an obese and hypertensive male patient with atypical symptoms of MI and was diagnosed as peptic ulcer. The ECG showed subtle ST elevation in inferior ECG leads and reciprocal changes in I and aVL. Highly sensitive troponin was elevated. Serial ECG showed evolution, thus revealed acute inferior MI. Successful percutaneous coronary intervention was performed. ECG is one of the most important diagnosis tools in STEMI and a cornerstone to direct the decision to immediate reperfusion therapy. Minimal ST-elevation often leads to inappropriate diagnosis, thus delayed the time to reperfusion. A study shows that 11-23% of STEMI do not reach the cutoff for accepted ECG criteria. In a study of infarctions with minimal ST-elevation, reciprocal changes are reported in 58% of all cases. Reciprocal ECG changes is extremely useful to help identifying STEMI in the absence of obvious ST-elevation on ECG
Implementation of an Education and Early Detection Program to Reduce the Risk of Occupational Lung Disease in Furniture Craftsmen in Sambirembe Village Ardyanto, Tonang Dwi; Myrtha, Risalina; Prabowo, Nurhasan Agung; Apriningsih , Hendrastutik; Dyanneza, Frieska; Kuncorowati, Niken Dyah Aryani; Nugroho, Novianto Adi; Suwandono, Adji; Sari, Maria Galuh Kamenyangan; Shofiyah, Laily
Sebatik Vol. 29 No. 2 (2025): December 2025
Publisher : STMIK Widya Cipta Dharma

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46984/sebatik.v29i2.2640

Abstract

Furniture industry workers in Sambirembe Village, Sragen, face significant health risks from exposure to wood dust, particularly an increased risk of Chronic Obstructive Pulmonary Disease (COPD). This research is prompted by the low awareness among workers regarding these risks and the minimal use of personal protective equipment (PPE). The objective of this program was to increase workers' and business owners' knowledge of lung health, promote early detection of COPD, and encourage the adoption of safer work practices. The method employed was an intervention that included health education and lung function screening via questionnaires and spirometry. The results revealed a critical knowledge gap, where over 85% of workers had never heard of COPD, even though 70% of them reported experiencing respiratory symptoms. Furthermore, over 90% of workers admitted to rarely using masks. The intervention, which combined education with personalized spirometry data feedback, proved effective in increasing worker awareness of tangible health risks. In conclusion, the education-based and health-screening intervention program successfully raised furniture workers' understanding of COPD risks. An approach that integrates information with personal medical evidence is crucial for promoting behavioural change in high-risk work environments.
The Importance of Hyperthyroid Screening in Acute Decompensated Heart Failure with Persistent Tachycardia Despite Optimal Decongestion: A Case Report Myrtha, Risalina; Wijayanto, Matthew Aldo; Prabowo, Nurhasan Agung
Jurnal Kardiologi Indonesia Vol 46 No 4 (2025): October - December, 2025
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.2006

Abstract

In “The Importance of Hyperthyroid Screening in Acute Decompensated Heart Failure with Persistent Tachycardia Despite Optimal Decongestion: A Case Report” (Indonesian Journal of Cardiology, 43(3), 123-9. https://doi.org/10.30701/ijc.1328), there is an error noted. An error has been found in the PDF version of this article. The DOI printed in the PDF is incorrect. The correct DOI is https://doi.org/10.30701/ijc.1328. The error occurs only in the PDF; the DOI listed in the article metadata is already correct.The publisher apologizes for any inconvenience caused by this error.DOI of original article: https://doi.org/10.30701/ijc.1328
Case Report: Pneumonia Provocate Thyroid Storm in Graves Disease Hermawati, Berty Denny; Prabowo, Nurhasan Agung; Putri, Desy Puspa; Myrtha, Risalina; Apriningsih, Hendrastutik
Smart Medical Journal Vol 6, No 1 (2023): April
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v6i1.68166

Abstract

Introduction: A thyroid crisis is an endocrine emergency involving many organ systems and can be fatal to the patient's survival. Although cases of thyroid crisis are rare, the mortality rate is significant which reaches 20–50%. The presence of comorbidities such as pneumonia infection increases the risk of death dramatically. Infection is a factor that can trigger thyroid crisis and exacerbate thyrotoxicosis. This condition of thyroid crisis most often occurs in people with hyperthyroidism caused by Graves' disease. We present the case of a patient with Graves' disease, aged 22 years, who developed a thyroid crisis due to community-acquired pneumonia infection. This study aims to provide a case report regarding the thyroid crisis due to pneumonia.Results: We carried out a physical and some appropriate supporting examinations to confirm the diagnosis. Wayne's index was 26, indicating hyperthyroidism. Assessment with Burch-Wartofsky obtained a score of 45, indicating suspicion of a thyroid storm. Then supportive care was provided to the patient. The community-acquired pneumonia as a triggering factor was treated with antibiotics. Thyrotoxicosis conditions were treated with antithyroid, beta-blocker, and glucocorticoid drugs. The patient's condition improved after treatment.Conclusion: It is crucial to detect and treat thyroid storm as quickly as possible since it has a high mortality rate. Wayne's score is useful for identifying hyperthyroidism based on clinical symptoms. The Burch-Wartofsky Point Scale scores are used to diagnose thyroid storms. Thyroid storm should be managed according to PERKENI (Perkumpulan Endokrinologi Indonesia) and ATA (American Thyroid Association) recommendations. This case serves as an example of how to make a proper diagnosis and treatment to prevent morbidity and death due to thyroid crisis.
A 21-Year-Old Woman with Suspecting Gitelman Syndrome Denny, Berty; Agung Prabowo, Nurhasan; Puspa Putri, Desy; Myrtha, Risalina; Apriningsih, Hendrastutik
Smart Medical Journal Vol 5, No 2 (2022): Smart Medical Journal
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v5i2.61735

Abstract

Introduction: Gitelman syndrome (GS), is a hereditary condition marked by a specific kidney function impairment. GS symptoms do not normally manifest until beyond the age of six years. We present a rare case of a 21-year-old woman with a background in generalized weakness muscle cramps with tetany, fever, and dyspnea.  The goal of this study is to give a case report of Gitelman syndrome suspicion.Result: Gitelman syndrome is identified through clinical indicators and lab testing, such as low potassium and magnesium levels in the blood, metabolic alkalosis, and low calcium levels in the urine. We do a variety of physical and laboratory tests to determine the disease and rule out other possibilities. Molecular proof is difficult to get due to a lack of resources and the high expense of genetic testing, which has become one of our case report's flaws. This patient was diagnosed as suspecting Gitelman syndrome and treated for electrolyte imbalances. The patients were given replacement therapy, which comprised intravenous potassium, sodium, and chloride therapy, as well as calcium therapy. In addition, we also provided some symptomatic therapy. She was discharged five days later in fine condition.Conclusion : This is one of the few reports of a 21-year-old lady being suspected of having Gitelman syndrome (GS). We conduct a battery of physical and laboratory tests to diagnose the disease and rule out other possibilities. We provide the appropriate therapies in accordance with the guidelines, and the outcomes are favorable.
Peningkatan Pengetahuan Petugas Kesehatan Mengenai Peran Spirometri Sebagai Alat Deteksi Dini Penyakit Paru Obstruktif Kronik (PPOK) di Fasilitas Kesehatan Layanan Primer Apriningsih, Hendrastutik; Prabowo, Nurhasan Agung; Ardyanto, Tonang Dwi; Myrtha, Risalina; Sari, Maria Galuh Kamenyangan; Shofiyah, Laily; Aryani, Niken Dyah; Nugroho, Novianto Adi; Dyanneza, Frieaska; Suwandono, Adji
Smart Society Empowerment Journal Vol 4, No 1 (2024): Maret
Publisher : Faculty of Medicine, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/ssej.v4i1.80196

Abstract

Pendahuluan: Penyakit Paru Obstruktif Kronik (PPOK) adalah salah satu dari sepuluh besar penyebab utama kematian di Indonesia. Prevalensi dan angka kematian akibat PPOK yang tinggi menunjukkan pentingnya deteksi dan tatalaksana dini PPOK. Underdiagnosis PPOK menurunkan akurasi data mortalitas, akurasi diagnosis yang terekam dalam database pada administasi kesehatan kurang jelas. Gold standard diagnosis PPOK adalah spirometri. Penerapan spirometri sebagai alat skrining mencakup penilaian besarnya underdiagnosis, intervensi potensial dan efektif, prediksi akurasi spirometri dan profil klinik spirometri. Pengabdian masyaratat ini bertujuan meningkatkan kemampuan tenaga kesehatan mengenai peran spirometri sebagai alat deteksi dini PPOK di fasilitas kesehatan primer.Metode: Pengabdian ini bekerjasama dengan Puskesmas Purwodiningratan Kota Surakarta. Metode yang digunakan dengan memberikan penyuluhan dan pelatihan spirometri kepada tenaga kesehatan di wilayah puskesmas tersebut. Untuk mengetahui tingkat pengetahuan tenaga kesehatan dilakukan evaluasi kegiatan berupa pre dan post-test mengenai soal-soal spirometri dasar.Hasil dan Pembahasan: Jumlah peserta kegiatan sebanyak 18 tenaga kesehatan tediri dari dokter umum dan perawat wilayah kerja Puskesmas Purwodiningratan. Hasil evaluasi menunjukkan bahwa tenaga kesehatan sudah mempunyai pengetahuan yang cukup mengenai spirometri, namun masih kurang dalam operasional dan interpretasi hasil spirometri. Sehingga masih memerlukan penyuluhan dan pelatihan. Hasil evaluasi didapatkan rerata nilai pre-test adalah 51,11 dan nilai post-test adalah 72,77. Sehingga terdapat peningkatan nilai sebesar 21,66 poin. Nilai pre-test terendah adalah 20 dan post-test adalah 50, sedangkan nilai pre-test tertinggi adalah 80 dan post-test adalah 100.Kesimpulan: Terdapat peningkatan pengetahuan tentang peran spirometri sebagai alat deteksi dini PPOK pada tenaga kesehatan di wilayah kerja Puskesmas Purwodiningratan.Kata kunci: spirometri; deteksi dini; PPOK; tenaga kesehatan; puskesmas Purwodiningratan 
Co-Authors Adji Suwandono Agung Prabowo, Nurhasan Anindita, Brigitta Devi Aprilningsih, Hendrastutik Apriningsih, Apriningsih Apriningsih Apriningsih, Hendrastutik Artika Ramadhani Aryani, Niken Dyah Ayusari, Amelya Augusthina Budiono, Enrico A. Denny, Berty Dewi, Herlina K. Dyanneza, Frieaska Dyanneza, Frieska Fadly, Ainal Febri Liantoni, Febri Gautama, Coana S. Hamka, Muhammad Farid Hermawati, Berty D. Hermawati, Berty Denny Ilyas, Muhana F. Irnizarifka Kuncorowati, Niken Dyah Aryani Maria Galuh Kamenyangan Sari, Maria Galuh Kamenyangan Modesty, Kyra Murasmita, Alamanda Nugroho, Novianto Adi Prabowo, Nurhasan A. Prabowo, Nurhasan Agung Priamas, Adigama Puspa Putri, Desy Putranto, Wachid Putri, Desy P. Putri, Desy Puspa Rahma, Annisa A. Rahman, Awalil R. K. Ratna Kusumawati Reviono Reviono Shofiyah, Laily Sukmagautama, Coana Tonang Dwi Ardyanto Tristan, Christopher D. Wijayanto, Matthew A. Wijayanto, Matthew Aldo Wulandari, Evi L.