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Evaluation of the Rationality of Antihypertensive Drug Use in Hypertension Patients at Peusangan Siblah Krueng Public Health Center, Bireuen District Adduana, Nuva; yuziani, yuziani; Novalia, Vera
Ahmad Dahlan Medical Journal Vol. 6 No. 2 (2025): November 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/admj.v6i2.14430

Abstract

Hypertension is a chronic disease with a high prevalence and a significant risk of serious complications if not properly managed. The aim of this study was to evaluate the rational use of antihypertensive drugs in hypertensive patients at Peusangan Siblah Krueng Public Health Center, Bireuen District, based on the criteria of appropriate indication, appropriate patient, appropriate drug, and appropriate dose according to JNC VIII guidelines. This was a descriptive observational study with a retrospective approach using medical records of hypertensive patients in 2023. A total of 185 patients were selected through purposive sampling based on inclusion and exclusion criteria. Data collected included patient identity, diagnosis, type of antihypertensive drugs, dosage, and administration. Rationality was evaluated using the 4T classification (appropriate indication, patient, drug, and dose) in accordance with JNC VIII guidelines. The results showed that appropriateness of indication and patient both reached 100%. Appropriateness of drug was 96.8%, with the majority of patients receiving amlodipine as the main therapy. Appropriateness of dose was 98.9%, with a small proportion of inappropriateness observed in patients with comorbid diabetes mellitus. Overall, the use of antihypertensive drugs in hypertensive patients at Peusangan Siblah Krueng Public Health Center, Bireuen District, can be categorized as rational based on the 4T criteria, although some discrepancies remain in drug selection and dosage, particularly among patients with comorbidities.
Evaluation of the use of Antibiotics Quantitatively and Qualitatively in Pharyngitis Patients at Banda Sakti Public Health Center Lhokseumawe Yuziani, Yuziani; Sofia, Rizka; Siregar, Fely Syah Imara
Media Farmasi: Jurnal Ilmu Farmasi Vol. 20 No. 2: September 2023
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v20i2.26122

Abstract

Pharyngitis is inflammation that occurs in the pharynx and often spreads to surrounding tissues which is one of the causes is a bacterial infection. Antibiotics are the main drug of choice for bacterial infection. Evaluation of the use of antibiotics can be done quantitatively and qualitatively. The importance of evaluating the use of antibiotics in pharyngitis patients can reduce drug side effects and prevent resistance. This study's objective was to evaluate if giving antibiotics to pharyngitis patients at Banda Sakti Public Health Lhokseumawe was appropriate, quantitatively using the Defined Daily Dose (DDD) method and qualitatively using the Gyssens method. This research is descriptive. The sampling technique used purposive sampling with a time-limited sampling method. The result showed that the use of antibiotics quantitatively using the DDD method found the highest total DDD was amoxicillin of 10,35 DDD/1000 patients, while the qualitative evaluation using the gyssens method for amoxicillin was classified as category IIIB because the gift was too short, cefadroxil was classified as category IVB because other antibiotics were safer, ciprofloxacin was classified as category V because it is not indicated. This study concludes that the use of antibiotics quantitatively using the DDD method found the highest total DDD was amoxicillin, while the evaluation of the use of antibiotics qualitatively classified inappropriate.