Article Per Year (5 Year)
p-Index From 2021 - 2026
3.264
P-Index
This Author published in this journals
All Journal E-Jurnal Medika Udayana Jurnal Surya Medika Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Jurnal Riset Kefarmasian Indonesia Jurnal Ilmiah Medicamento Media Farmasi Indonesia Usadha Jurnal Kefarmasian Indonesia
Suradnyana, I Gede Made
Fakultas Farmasi Universitas Mahasaraswati Denpasar
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

Published : 22 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 22 Documents
Search

 1   2   3 
Formulasi serta Evaluasi Aktivitas Antioksidan dan Tabir Surya Secara in Vitro Pada Krim Ekstrak Etanol Daun Sukun (Artocarpus altilis) Suradnyana, I Gede Made; Juli Widiarta, I Made; Yudianti Mendra, Ni Nyoman
Usadha Vol 4 No 2 (2025): Usadha : Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v4i2.12757

Abstract

Ultraviolet (UV) radiation exposure can cause various skin disorders, including sunburn, erythema, premature aging, wrinkles, pigmentation changes, and DNA damage, which may lead to photocarcinogenesis. Sunscreens play an important preventive role against these harmful effects, yet synthetic organic and inorganic agents may cause skin toxicity. Breadfruit (Artocarpus altilis) leaf extract contains phenolic compounds with dual photoprotective properties as antioxidants and UV filters. This study aimed to formulate and evaluate a sunscreen cream containing ethanol extract of breadfruit leaves. The formulation varied the concentrations of stearic acid and triethanolamine as emulsifiers. Physical properties (organoleptic, homogeneity, pH, adhesion, and spreadability) and in vitro activities (antioxidant by DPPH method and SPF by spectrophotometry) were assessed and compared with commercial creams. The results showed that the cream formulation containing 4% stearic acid and 2% triethanolamine exhibited the most ideal physical characteristics compared to commercial products. The breadfruit leaf ethanol extract cream demonstrated weak to moderate antioxidant activity, while at a concentration of 400 ppm, it exhibited sunscreen protection categorized as maximum protection. The ethanol extract of breadfruit leaves has the potential to be developed into a natural sunscreen formulation that is safe and environmentally friendly.
OPTIMASI KOMBINASI COCOA BUTTER DAN MILK BUTTER SEBAGAI BASIS BODY BUTTER EKSTRAK ETANOL DAUN JAMBU BIJI (Psidium guajava Linn) Suradnyana, I Gede Made; Mahardika, I Komang Gede; Siada, Nyoman Budiartha
Jurnal Riset Kefarmasian Indonesia Vol. 4 No. 2 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i2.242

Abstract

Guava leaf extract is known to contain flavonoids, a class of flavone compounds that have very strong antioxidant activity. The antioxidant activity of guava leaf ethanol extract as measured by the DPPH method showed an IC50 value of 72 µg/ml. Body butter preparations have a better ability to nourish and maintain skin moisture because they contain high oil components. Cocoa butter and milk butter are the bases that are widely used in body butter formulas and are able to maintain skin health. This study aims to determine the area of optimum composition of the combination of cocoa butter and milk butter in body butter preparations of guava leaf ethanol extract (Psidium guajava L.). This study used a factorial design with two factors, namely cocoa butter and milk butter and two levels, namely 2% and 4% for cocoa butter and 2% and 15% for milk butter. The observed responses were pH and spreadibility with data analysis using Design Expert and SPSS software. Based on the results of the research, the optimum area for the combination of cocoa butter and milk butter with the pH equation is Y = 6.00000 – 1.77504(X1) – 4.73345 (X2) + 1.8336(X1X2) and the dispersion equation is Y = 3 ,77692+0,366667(X1) – 0,005128(X2) + 0.033333(X1X2). The optimal composition area of cocoa butter and milk butter has been validated on the combination of 3% cocoa butter and 8,5% milk butter.
Co-Authors Aditya Putra, Aditya Anita Dewi, Ni Luh Kade Arman Antari, Ni Putu Pina Apriliani, Wayan Ariawa, Dewi Cahayani Debby Juliadi Dewi Agustini, Ni Putu Dewi, Ni Luh Samila Erna Cahyaningsih Gusti Ayu Putu Laksmi Puspa Sari I Kadek Wirata I Komang Gede Mahardika Intansari, Ni Putu Ocha Indira Juli Widiarta, I Made Ketut Agus Adrianta Mahardika, I Komang Gede Megawati, Fitria Mendra, Ni Nyoman Yudianti Ni Made Dharma Shantini Suena Ni Made Dwi Mara Widyani Nayaka Ni Made Puspayanti, Ni Made Ni Made Sukma Sanjiwani Ni Putu Gek Dyah Citra Vitaloka Ni Putu Udayana Antari Nyoman Budiartha Siada Perayanthi, Reni Puspita Wati, Ni Putu Putu Era Sandhi Kusuma Yuda Rahadi , I Wayan Surya RR. Asih Juanita Sugiyanto, Milyadi Tiarini, Diah Galuh Vernandes Sasadara, Maria Malida Wardani, I Gusti Agung Ayu Kusuma Wirata, I Kadek Yudianti Mendra, Ni Nyoman