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Hydrophilic Surfaces Turning of Graphene Nano Platelets by 1,3,6-Trihydroxyxanthone: π–π Stacking Interaction Affair in 2-D Yuanita, Emmy; Sirojuttolibin, Sirojuttolibin; Dharmayani, Ni Komang Tri; Ulfa, Maria; Septiyana, Maulida; Sudirman, Sudirman
Indonesian Journal of Chemistry Vol 25, No 3 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.89894

Abstract

Graphene nanoplatelet (GNP) has a good potential to be developed as a drug carrier material. In this study, the interaction of GNP with one type of drug, namely 1,3,6-trihydroxyxanthone (THX), has been studied. The results of XRD analysis and FTIR uptake show an excellent interaction between THX and GNP through the π–π stacking channel. This interaction makes the GNP surface more polar and soluble in the aqueous media. THX-graphene shows physical and chemical stabilities, where THX can be released under specific and controlled conditions. The results of this study show the potential of utilizing graphene as a drug carrier material for more specific disease targets with a longer drug release time.
ABC Index Analysis: Physical Properties of Prenylated Xanthone Pratiwi, Lia Fitta; Mufarrihati, Ardelia; Dharmayani, Ni Komang Tri; Wardhana, I Gede Adhitya Wisnu
JURNAL DIFERENSIAL Vol 7 No 2 (2025): November 2025
Publisher : Program Studi Matematika, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jd.v7i2.20418

Abstract

Xanthone is a heterocyclic compound with various substituents (hydroxy, prenyl, geranyl, methoxy, halogens, and others). The presence of these substituents contributes to diverse biological activities, including anticancer, antidiabetic, and antioxidant properties. This study aims to optimize the design of xanthone derivatives through a mathematical approach using Chemical Topological Graphs (CTG) and the Atom-Bond Connectivity (ABC) index. A literature review was conducted to identify the physicochemical properties, biological activities, and molecular structures of compounds such as 1,7-dihydroxy-3-methoxy-2-(3-methylbut-2-enyl)xanthone (1), Gartanin (2), and Garcinon (3). These xanthone derivatives are distinguished by the number of prenyl substitutions on their core structures. Chemical graph theory is employed to represent molecular structures, with atoms represented as nodes and chemical bonds as edges. The ABC index is calculated based on the degree of connected atoms within the molecules and correlated with the compounds’ physicochemical properties and bioactivity. The ABC index values for compounds (1), (2), and (3) are 32.186, 43.987, and 51.744, respectively. These values indicate that an increase in prenyl substitutions leads to higher ABC index values, which correspond to decreased polarity, increased boiling points, and enhanced bioactivity and stability of the xanthone derivatives
Analisis Hubungan Nilai Indeks Zagreb dengan Titik Didih dan Kestabilan Senyawa Kerangka Dasar Calamenene Sabil, M. Ibnu; Miftahurrahman, Miftahurrahman; Wardhana, I Gede Adhitya Wisnu; Dharmayani, Ni Komang Tri
JURNAL DIFERENSIAL Vol 7 No 2 (2025): November 2025
Publisher : Program Studi Matematika, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jd.v7i2.20431

Abstract

A new compound, dysoxyphenol, isolated from Dysoxylum densiflorum, has acalamenene-based framework. The structure of dysoxyphenol is classified as a sesquiterpene. Thisstudy discusses the relationship between Zagreb Index values and the physical properties andstability of two compounds: calamenene and dysoxyphenol. The Zagreb Index, consisting of thefirst and second indices, is used to measure the structural stability of a graph through the sum ofsquared vertex degrees. The objective of this analysis is to determine the Zagreb Index values forcalamenene and dysoxyphenol, to measure the boiling points and stability of the compounds. Thisanalysis was carried out by examining the structures of calamenene and dysoxyphenol. The obtainedstructures were then analyzed graphically. The results of this study show that the first and secondZagreb Index values for calamenene are 262 and 340, which are smaller compared to the first andsecond Zagreb Index values for dysoxyphenol, which are 264 and 350, respectively. This indicatesthat calamenene has a lower boiling point than dysoxyphenol and is more stable than dysoxyphenol.
PENGARUH ASAM HUMAT SEBAGAI PELENGKAP PUPUK PADA TANAMAN JAGUNG TERHADAP EFISIENSI PEMUPUKAN DI LAHAN KERING KEC. BAYAN KAB. LOMBOK UTARA NTB (THE INFLUENCE OF HUMIC ACID AS FERTILIZER SUPPLEMENT ON MAIZE PLANT TO FERTILIZING EFFICIENCY IN UNIRRIGATED LAN Hermanto, Dhoni; Tri Dharmayani, Ni Komang; Kurnianingsih, Rina; Kamali, Siti Raudhatul
Jurnal Ilmu-Ilmu Pertanian Vol. 16 No. 2 (2012): Desember
Publisher : Politeknik Pembangunan Pertanian Yogyakarta-Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

A study of the influence of humic acid as fertilizer supplement on maize plant to fertilizing efficiency in unirrigated land of Kec. Bayan Kab. Lombok Utara NTB was conducted. Agricultural land of Kec. Bayan has the physical properties of sandy texture, loose structure and reddish brown with neutral acidity (pH 6.97 at a depth of 0-20 cm and a pH of 6.8 at a depth of 21-40 cm). In addition, it has low nutrient level of soil (Corganic, N, P, K) at depths 0-20 cm and 21-40 cm respectively are 0.912% and 1.150%; 0.064% and 0.074%; 0.001% and 0.005 %; 0.290% and 0.310%. Application of humic acid as fertilizers supplement improved the availability of major and micronutrients and enhanced their uptake. The highest availability and uptake of N, P and K was found in addition of humic acid @ 20 kg ha-1 along with 100% recommended dose of fertilizers. Application of humic acid in soil showed increasing of plant growth (plant height, weight and nutritional value of corn). Fertilized N, P and K without humic acid was provided of fertilizing efficiency below 50 %. The most efficient dose for humic acid fertilizer is 20 kg ha-1 along with 150 kg ha-1 of urea, 200 kg ha-1 of SP36 and 50 kg ha-1 of KCl.
Profile of a Composite Based on Bacterial Cellulose and Polyvinyl Alcohol as a Drug Release Matrix for Tetracycline Hydrochloride Sukmaningrum, Afif Dwi; Yuanita, Emmy; Dharmayani, Ni Komang Tri; Sudirman, Sudirman; Sudewianingsih, Ni Made; Ulfa, Maria
Jurnal Riset Kimia Vol. 15 No. 2 (2024): September
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v15i2.692

Abstract

Bacterial cellulose (BC) is a natural polymer with good mechanical properties and hydrophilicity. Polyvinyl alcohol (PVA) is a synthetic polymer widely used in medicine. Both have been researched for their potential in drug release and acceptance. This study aims to determine the role of BC and PVA as drug release matrices for tetracycline hydrochloride (TCH), with additional fillers such as graphite (G) and TiO2. The results showed that the composites with BC matrix had lower mechanical properties than those with PVA matrix, with tensile strength values of 6.4075 and 17.446 MPa, respectively. However, the BC matrix was superior in porosity and swelling ability. The drug release testing of TCH from the composites showed that the appropriate model to describe drug release in BC matrix composites was in zero order, while the PVA matrix was in first order. The antibacterial activity of the composites on both matrices was tested against Staphylococcus aureus. The results indicate that both composites have potential applications in promising biomedical fields.
MENGOPTIMALKAN PEMANFAATAN SUMBER DAYA KENTANG: KETERLIBATAN MASYARAKAT DAN PENINGKATAN KETERAMPILAN DALAM MENGGALI POTENSI TINGGI TEPUNG KENTANG DI DESA WISATA SEMBALUN BUMBUNG Dharmayani, Ni Komang Tri; Yuanita, Emmy; Ulfa, Maria; Ningsih, Baiq Nila Sari; Sudirman, Sudirman; Septiyana, Maulida; Wardhana, I Gede Adhitya Wisnu
Jurnal Pengabdian Inovasi Masyarakat Indonesia Vol. 3 No. 1 (2024): Edisi Februari
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpimi.v3i1.3344

Abstract

Potatoes are one of the staple crops widely cultivated worldwide, with significant production, especially in Europe and North America. However, the economic potential of potatoes has not been fully harnessed, particularly in villages like Sembalun Bumbung, West Nusa Tenggara Province, Indonesia. This article outlines a community engagement approach aimed at enhancing the understanding and skills of the community in utilizing potato flour as a valuable local resource. The implementation methodology involves three main approaches: knowledge transfer, technology transfer, and mentoring. The activities encompass education, hands-on training, as well as testing and evaluating processed potato flour products, particularly noodles. The results of the program demonstrate high enthusiasm among participants, who have successfully produced high-quality potato flour and noodles. This program provides new opportunities for the community to utilize potatoes as an additional source of income and has the potential to significantly boost the village's economy.
Sosialisasi Pengemasan Produk SMART (Sehat, Menarik, Aman, Ramah Lingkungan, dan Tepat Sasaran) Bagi Masyarakat Desa Sembalun Bumbung Sebagai Upaya Meningkatkan Nilai Jual Produk Lokal Di NTB Ningsih, Baiq Nila Sari; Sudirman, Sudirman; Dharmayani, Ni Komang Tri; Yuanita, Emmy; Ulfa, Maria
Jurnal Pengabdian Inovasi Masyarakat Indonesia Vol. 3 No. 1 (2024): Edisi Februari
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpimi.v3i1.3346

Abstract

Desa Sembalun Bumbung, yang terletak di lereng Gunung Rinjani, memiliki potensi alam besar dan diakui sebagai World Geopark oleh UNESCO. Meskipun desa ini menghasilkan berbagai produk pertanian dan perkebunan, kebanyakan produk hanya dijual dalam bentuk bahan mentah, terutama untuk wisatawan yang berkunjung langsung. Pengabdian ini berfokus pada upaya meningkatkan pengetahuan dan keterampilan warga Desa Sembalun Bumbung dalam pengemasan produk pertanian dengan metode SMART (Sehat, Menarik, Aman, Ramah Lingkungan, dan Tepat Sasaran). Kegiatan ini melibatkan pendekatan transfer pengetahuan, transfer teknologi, serta pembinaan dan pendampingan. Produk yang menjadi fokus adalah kopi bubuk dan black onion, dengan pengemasan yang lebih inovatif dan estetis. Selain itu, pelatihan juga mencakup pembukaan toko online di e-commerce dan teknik copywriting. Hasil kegiatan menunjukkan bahwa pelatihan berhasil meningkatkan pengetahuan dan keterampilan peserta dalam pengemasan produk. Beberapa dari mereka bahkan tertarik untuk menjalankan bisnis online. Dengan pengemasan yang baik dan pemasaran yang tepat, produk hasil olahan dari Desa Sembalun Bumbung memiliki peluang untuk meningkatkan pendapatan dan berkontribusi pada pertumbuhan ekonomi lokal.
Sosialisasi Pengemasan Produk dengan Plastik Biodegradable Berbahan Selulosa dan Strategi Pemasarannya di Kelompok Wanita Tani Alummahat, Lendang Nangka, Lombok Timur, NTB Ningsih, Baiq Nila Sari; Ulfa, Maria; Yuanita, Emmy; Dharmayani, Ni Komang Tri; Septiyana, Maulida; Haviz, Nur Vinna; Hayani, Hafiyatul; Tamara, Cynthia Claudia; Septiari, Wayan Uni
Jurnal Pengabdian Inovasi Masyarakat Indonesia Vol. 3 No. 2 (2024): Edisi Agustus
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpimi.v3i2.6002

Abstract

Desa Lendang Nangka di Lombok Timur, NTB, yang termasuk dalam World Geopark UNESCO di lereng Gunung Rinjani, memiliki potensi besar dalam sektor pertanian. Namun, tantangan muncul dalam pengemasan produk pertanian yang belum ramah lingkungan. Kegiatan ini bertujuan meningkatkan nilai produk pertanian bagi kelompok Wanita Tani Alummahat melalui penggunaan kemasan ramah lingkungan berbahan selulosa dengan metode gelatinisasi dan pemasaran melalui e-commerce. Pelaksanaan kegiatan melibatkan transfer pengetahuan, teknologi, serta pembinaan dan pendampingan untuk memastikan peningkatan nilai ekonomi lokal secara berkelanjutan. Kegiatan meliputi penyuluhan, pelatihan praktis, dan pembentukan Kelompok Usaha Bersama (KUB) sebagai wadah pengembangan ide inovatif. Evaluasi menunjukkan peningkatan signifikan dalam pengetahuan dan keterampilan partisipan terkait pengemasan ramah lingkungan, serta antusiasme yang tinggi. Program ini berkontribusi pada pengembangan strategi pemasaran dan pengemasan yang berkelanjutan di tingkat desa, dengan harapan dapat memberikan dampak positif pada ekonomi masyarakat lokal.
Synthesis and Characterization of Composites-Based Bacterial Cellulose by Ex-Situ Method as Separator Battery Ulfa, Maria; Noviani, Inda; Yuanita, Emmy; Dharmayani, Ni Komang Tri; Sudirman; Sarkono
Jurnal Penelitian Pendidikan IPA Vol 9 No 6 (2023): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i6.3819

Abstract

Many studies have been conducted and developed on cellulose-based battery separator materials, including bacterial cellulose, which has characteristics like plant cellulose. This research aims to synthesize BC/Al2O3 composite and analyze its potential as a battery separator. The synthesis of the composite with the ex-situ method is to immerse BC from tofu liquid waste (fermentation time variation of 6, 7, and 8 days) into Al2O3 suspension. The characterization results showed that the immersion of Al2O3 in BC can increase porosity, electrolyte absorption, and conductivity, indicating that the composite has the potential to be used as a battery separator.
Antibacterial Activity of Marine Sponge (Stylotella sp.) Dharmayani, Ni Komang Tri; Isnaini; Ulfa, Maria; Sudirman; Yuanita, Emmy; Sariningsih, Baiq Nila
Jurnal Penelitian Pendidikan IPA Vol 9 No 6 (2023): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i6.3839

Abstract

Sponges are marine biota that makes up coral reefs that live on the bottom of the waters and have an important role in marine ecosystems. Sponges have bioactive components that have not been widely used by the community. This study aimed to analyze the content of secondary metabolites and the antibacterial activity of the sponge Stylotella sp. antibacterial activity test against Gram-negative (-) Escherichia coli and Gram-positive (+) Staphylococcus aureus was carried out using the good diffusion method. The results of antibacterial testing with various concentrations of 50, 100, and 150 ppm of the isolates showed that the zone of inhibition against E. coli was 11.3; 12; and 13 mm while for S. aureus was 12.3; 13; and 14 mm. The results of antibacterial testing with a concentration of 600 ppm of sponge extract showed an inhibition zone on E. coli and S. aureus in the amount of 13.3 and 14 mm, respectively. The test results showed that the sponge extract and isolate were in the intermediate category and were resistant to E. Coli bacteria. and S. Aureus