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All Journal Jurnal Ilmu Pertanian VALENSI Indonesia Chimica Acta Science and Technology Indonesia Jurnal Penelitian Pendidikan IPA (JPPIPA) Indonesian Journal of Chemistry Jurnal Pengabdian Magister Pendidikan IPA jurnal Ilmu Pertanian (Agricultural Science) Acta Chimica Asiana Jurnal Ilmiah Abdi Mas TPB Unram Jurnal Warta Desa (JWD) Jurnal Pendidikan dan Pengabdian Masyarakat Jurnal Pengabdian Inovasi Masyarakat Indonesia Molekul: Jurnal Ilmiah Kimia Jurnal Ilmiah Multidisiplin
Tri Dharmayani, Ni Komang
Universitas Mataram
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Education Engineering Environmental Science Materials Science & Nanotechnology Physics Social Sciences Other

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Antibacterial Activity of Marine Sponge (Stylotella sp.) Ni Komang Tri Dharmayani; Isnaini; Maria Ulfa; Sudirman; Emmy Yuanita; Baiq Nila Sariningsih
Jurnal Penelitian Pendidikan IPA Vol 9 No 6 (2023): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i6.3839

Abstract

Sponges are marine biota that makes up coral reefs that live on the bottom of the waters and have an important role in marine ecosystems. Sponges have bioactive components that have not been widely used by the community. This study aimed to analyze the content of secondary metabolites and the antibacterial activity of the sponge Stylotella sp. antibacterial activity test against Gram-negative (-) Escherichia coli and Gram-positive (+) Staphylococcus aureus was carried out using the good diffusion method. The results of antibacterial testing with various concentrations of 50, 100, and 150 ppm of the isolates showed that the zone of inhibition against E. coli was 11.3; 12; and 13 mm while for S. aureus was 12.3; 13; and 14 mm. The results of antibacterial testing with a concentration of 600 ppm of sponge extract showed an inhibition zone on E. coli and S. aureus in the amount of 13.3 and 14 mm, respectively. The test results showed that the sponge extract and isolate were in the intermediate category and were resistant to E. Coli bacteria. and S. Aureus
Pencegahan Stunting Melalui Kegiatan Sosialisasi Hidup Sehat dan Makanan Bergizi di Desa Tirtanadi Kecamatan Labuhan Haji Ni Komang Tri Dharmayani; Erwin Jayadi Putra; Nurlely Shabna Syundari; Baiq Nurmayana; Ira Agustina; Nur Indrianingsih M.G Indrianingsih; Ernidasari Rohmati; Devy Febriana; Kadek Yefta Christian; Ridho Abdi Saputra
Jurnal Pengabdian Inovasi Masyarakat Indonesia Vol. 1 No. 2 (2022): Edisi Agustus
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (226.086 KB) | DOI: 10.29303/jpimi.v1i2.1482

Abstract

Stunting is a chronic nutritional problem resulting from a state of malnutrition that lasts long enough. One area in Indonesia that still faces stunting problems is Tirtanadi village, Labuan haji sub-district, East Lombok district, West Nusa Tenggara province. Factors that cause stunting are low understanding of stunting and poor sanitation. Both of these things lead to a lack of nutritional intake for infants, children, and pregnant women. One of the efforts to prevent stunting can be done by utilizing agricultural products to be processed high in nutrition. Tirtanadi Village is a producer of corn as the main agricultural product and has not been used optimally. Corn is processed into various types of food such as pudding and corn nuggets with a high taste. The utilization of corn in processed food with a preferred taste can be done to increase the family's nutritional intake while at the same time increasing the family's economy.
Sosialisasi Pemanfaatan Nira Aren Sebagai Bahan Baku Pembuatan Nata Kepada Masyarakat Desa Jurit Baru, Kabupaten Lombok Timur, NTB Ni Komang Tri Dharmayani; Surya Hadi; Emmy Yuanita; Maria Ulfa
Jurnal Pengabdian Inovasi Masyarakat Indonesia Vol. 2 No. 1 (2023): Edisi Februari
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (238.544 KB) | DOI: 10.29303/jpimi.v2i1.1978

Abstract

Desa Jurit Baru merupakan salah satu desa di kabupaten Lombok Timur yang memiliki hasil perkebunan berupa nira aren. Selama ini nira aren yang didapatkan belum dimanfaatkan secara optimal. Salah satu olahan nira aren yang dapat dijadikan bahan makanan adalah produk nata. Oleh sebab itu dilakukan suatu kegiatan sosialisasi melalui program pengabdian kepada masyarakat yang bertujuan meningkatan pengetahuan, sikap, dan keterampilan masyarakat Jurit Baru tentang pemanfaatan nira aren sebagai bahan baku pembuatan nata serta merangsang minat kewirausahaan peserta. Target khusus program ini berupa produk nata yang menggunakan nira aren sebagai bahan dasarnya. Kegiatan ini terdiri dari 3 tahapan yaitu: (1) penyuluhan mengenai pemahaman secara teoritis mengenai pengertian teknologi fermentasi pada pembuatannya; (2) praktik pembuatan nata dari nira aren; serta (3) pendampingan kegiatan produksi dan pengemasan. Kegiatan pelatihan dan pembinaan perlu dilakukan secara berkesinambungan untuk mencapai tujuan utama dari kegiatan ini yaitu meningkatkan perekonomian masyarakat.
Molecular Docking of Xanthone Derivatives as Therapeutic Agent for Covid-19 Emmy Yuanita; Sudirman Sudirman; Ni Komang Tri Dharmayani; Maria Ulfa; Saprizal Hadisaputra; Jufrizal Syahri
Molekul Vol 17 No 1 (2022)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2022.17.1.5600

Abstract

Covid-19 has caused more than 14 million confirmed cases and more than 6 hundred deaths as of 21 July 2020 globally. However, there is no approved drug to treat the disease. Xanthone is a potential therapeutic option for the virus that have been tested using molecular docking. There were 12 of xanthone compounds and its derivatives which have been docked against two protein crystals, 2GX4.pdb and 6FV1.pdb, which obtained two potential compounds of hydroxyxanthone derivatives with sulfonate and chloro substitution. These compounds are potentially developed into one of the agents for the treatment of infection COVID-19 disease. Based on energy data and interactions with amino acid residues when compared with its own native ligands, namely NOL and E8E, respectively. Energy docking and energy docking interactions are equal to - 43.3057and - 45.5805 Kcal/mol respectively, during interactions with amino acid residues in the form of Gly 142, His 163, Cys144, Glu166, Gln164 and His 41. Based on these two data, it can be concluded that trihydroxyxanthone compounds 4 and 8 with chloro and sulfonate substitution are very potential to be developed as drug agents for Covid-19 disease therapy through protease inhibition.
Profiling of Modified Chitosan-Based Composites as Tetracycline Hydrochloride Drug Release Systems Anjartikasari, Nurul; Yuanita, Emmy; Dharmayani, Ni Komang Tri; Sudirman, Sudirman; Sudewianingsih, Ni Made; Ulfa, Maria
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 17, No 1: June 2024
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/ica.v17i1.33590

Abstract

Controlled drug release systems (DRS) are a crucial technology in the medical field, and they continue to be developed today. Chitosan is useful in manufacturing-controlled drug release systems due to its non-toxic, biodegradable, and biocompatible properties. However, it has some limitations when it comes to its physical and mechanical properties. Combining chitosan with other materials, such as bacterial cellulose (BC), graphite (Gr), ZnO, and TiO2, can improve its mechanical properties and antibacterial activity. This study aims to synthesize Chi/BC/Gr/TiO2 and Chi/BC/Gr/ZnO composites as drug release systems. When tested with TCH, an antibiotic model, the drug release kinetics of the composite followed the Hixson-Crowell and Korsmeyer-Peppas kinetics models. Additional tests for physical and mechanical properties, as well as antibacterial activity, have also been conducted. Mechanical properties in terms of tensile strength and Young’s modulus in composites with adding Gr, TiO2, and ZnO have higher values than Chi/BC alone. Compared to positive control, both TCH-loaded composites show higher inhibition against S. aureus bacteria. Based on the results of this study, composite Chi/BC/Gr/TiO2 and Chi/BC/Gr/ZnO have potential applications as DRS such as wound dressing.
Modified Bacterial Cellulose-Based Composite Profile for Drug Release of Tetracycline Hydrochloride Cahyani, Ni Wayan Chyntia Pramesti; Yuanita, Emmy; Dharmayani, Ni Komang Tri; Sudirman, Sudirman; Sudewianingsih, Ni Made; Ulfa, Maria
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 10, No. 1, May 2024
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v10i1.37663

Abstract

Bacterial cellulose (BC) is a biodegradable natural polymer with high mechanical strength and non-toxicity. This biopolymer is widely used as a candidate in biomedical fields, such as drug delivery, wound healing, and filtration systems. However, BC lacks antibacterial activity which limits its use in biomedical applications. So, modification of BC-based composite is required. This study aims to examine the effects of modifying BC-based composites with fillers such as graphite (G) and polyvinyl alcohol (PVA) on the release of tetracycline hydrochloride (TCH) drugs. Adding fillers to BC can alter its physical and mechanical properties, reducing its porosity and swelling rate in acidic and alkaline mediums. The drug release of TCH from modified BC-based composites follows the Korsmeyer-Peppas and Hixson-Crowell kinetics models. Adding filler and TCH antibiotic to the composite enhances its antibacterial activity against Staphylococcus aureus with a significant inhibition zone. The results of the inhibition zone show that composites have the potential to be applied in biomedical fields, especially in transdermal patches.
Sosialisasi Pengemasan Produk dengan Plastik Biodegradable Berbahan Selulosa dan Strategi Pemasarannya di Kelompok Wanita Tani Alummahat, Lendang Nangka, Lombok Timur, NTB Ningsih, Baiq Nila Sari; Ulfa, Maria; Yuanita, Emmy; Dharmayani, Ni Komang Tri; Septiyana, Maulida; Haviz, Nur Vinna; Hayani, Hafiyatul; Tamara, Cynthia Claudia; Septiari, Wayan Uni
Jurnal Pengabdian Inovasi Masyarakat Indonesia Vol. 3 No. 2 (2024): Edisi Agustus
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpimi.v3i2.6002

Abstract

Desa Lendang Nangka di Lombok Timur, NTB, yang termasuk dalam World Geopark UNESCO di lereng Gunung Rinjani, memiliki potensi besar dalam sektor pertanian. Namun, tantangan muncul dalam pengemasan produk pertanian yang belum ramah lingkungan. Kegiatan ini bertujuan meningkatkan nilai produk pertanian bagi kelompok Wanita Tani Alummahat melalui penggunaan kemasan ramah lingkungan berbahan selulosa dengan metode gelatinisasi dan pemasaran melalui e-commerce. Pelaksanaan kegiatan melibatkan transfer pengetahuan, teknologi, serta pembinaan dan pendampingan untuk memastikan peningkatan nilai ekonomi lokal secara berkelanjutan. Kegiatan meliputi penyuluhan, pelatihan praktis, dan pembentukan Kelompok Usaha Bersama (KUB) sebagai wadah pengembangan ide inovatif. Evaluasi menunjukkan peningkatan signifikan dalam pengetahuan dan keterampilan partisipan terkait pengemasan ramah lingkungan, serta antusiasme yang tinggi. Program ini berkontribusi pada pengembangan strategi pemasaran dan pengemasan yang berkelanjutan di tingkat desa, dengan harapan dapat memberikan dampak positif pada ekonomi masyarakat lokal.
Analisis Fitokimia dan Uji Aktivitas Antioksidan Residu Destilasi Uap Daun Gaharu dari Tiga Varietas serta Pemanfaatannya Sebagai Teh Rizkyani, Azizah; Dharmayani, Ni Komang Tri; Handayani, Sri Seno
Jurnal Ilmiah Multidisipin Vol. 2 No. 5 (2024): Jurnal Ilmiah Multidisiplin, Mei 2024
Publisher : Lumbung Pare Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Daun gaharu (Gyrinops versteegii) diduga mempunyai aktivitas sebagai antioksidan. Aktivitas antioksidan yang dimiliki oleh daun gaharu dikarenakan adanya kandungan senyawa metabolit sekunder seperti fenol, flavonoid, terpenoid dan tanin yang diketahui bertanggung jawab terhadap aktivitas antioksidan. Selain senyawa metabolit sekunder terdapat juga kandungan asam lemak yang memiliki aktivitas sebagai antioksidan seperti asam palmitat. Tujuan dari penelitian ini yaitu untuk mengetahui kandungan senyawa pada residu destilasi uap daun gaharu dari tiga varietas yaitu beringin, buaya dan madu dan aktivitas antioksidannya serta standarisasi teh residu daun gaharu. Simplisia residu daun gaharu diekstraksi dengan metode maserasi dan ekstraksi cair-cair. Uji aktivitas antioksidan dengan metode DPPH dan analisis kandungan senyawa menggunakan analisis GC-MS. Hasil uji aktivitas antioksidan ekstrak metanol menunjukkan aktivitas antioksidan yang tergolong kuat dengan nilai IC50 berturut-turut dari tiga varietas. Varietas beringin 57,535 ppm, varietas buaya 47,350 ppm dan varietas madu 46,652 ppm. Hasil Uji aktivitas antioksidan fraksi n-heksana menunjukkan aktivitas antioksidan yang lemah pada varietas beringin dengan nilai IC50 209,296 ppm dan varietas buaya dengan nilai IC50 92, 842 ppm dan varietas madu dengan nilai IC50 69,724 ppm yang tergolong antioksidan sedang. Teh residu daun gaharu telah memenuhi standarisasi teh berdasarkan (SNI-3836-2013) dan berdasarkan pengujian organoleptik teh dari residu destilasi uap daun gaharu untuk parameter warna dan rasa dapat diterima oleh panelis sedangkan untuk parameter aroma belum dapat diterima oleh panelis.
Potensi Kulit Batang Berbagai Varietas Gaharu (Gyrinops versteegii (Gilg.) Domke) Sebagai Antikanker Lestari, Dian; Hadi, Surya; Dharmayani, Ni Komang Tri
Jurnal Ilmiah Multidisipin Vol. 2 No. 10 (2024): Jurnal Ilmiah Multidisiplin, Oktober 2024
Publisher : Lumbung Pare Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tujuan dari penelitian ini adalah untuk menentukan aktivitas antikanker dari kulit batang berbagai varietas gaharu (Gyrinops versteegii (Gilg.) Domke). Sampel kulit batang tiga varietas gaharu (Gyrinops versteegii (Gilg.) Domke) diambil dari dusun Kerujuk desa Pemenang Barat dan Hutan Pusuk Lestari desa Lembah Sari. Setiap sampel dalam penelitian ini diekstraksi menggunakan metanol selama 3x24 jam. Ekstrak metanol diuji toksisitas menggunakan Brine Shrimp Lethality Test (BSLT). Hasil uji menunjukkan bahwa ketiga ekstrak metanol tersebut memiliki toksisitas yang signifikan (LC50 < 1000 µg/mL). Varietas Buaya memiliki sifat toksik paling tinggi dibandingkan dua varietas lainnya (LC50 45,94 µg/mL). Hasil tersebut menunjukkan ekstrak metanol kulit batang gaharu (Gyrinops versteegii (Gilg.) Domke) varietas Buaya memiliki potensi besar sebagai agen antikanker dimasa depan. Gaharu (Gyrinops versteegii (Gilg.) Domke) varietas Buaya dianalisis menggunakan instrumen GC-MS untuk mengetahui senyawa yang diduga berperan terhadap sifat toksik. Analisis GC-MS menunjukkan terdapat 57 puncak senyawa, sebelas dari 57 puncak yang diduga berperan terhadap sifat toksik yaitu α-kariofilen; β-santalol; Kauran-18-al,17-(asetiloksi)-, (4. β); 1,4-benzendiol,2-metil; inosine; 2,3-dimetilhidrokuionon; tetrametil-p-benzokuinon; 5-metil-benzofurazan; Benzofuran; Piridoksilamin; 2-Propanamida,2-metil-N-fenil.
Synthesis and characterization of 2,4,6-trihydroxy benzophenone and its activity as sunscreen Yuanita, Emmy; Rohmana, Ainni; Ulfa, Maria; Ningsih, Baiq Nila Sari; Sudirman, Sudirman; Dharmayani, Ni Komang Tri; Lestarini, Ima Arum; Septiyana, Maulida; Ratnasari, Baiq Desy
Acta Chimica Asiana Vol. 8 No. 1 (2025)
Publisher : The Indonesian Chemical Society, Chapter Nusa Tenggara and The University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v8i1.175

Abstract

Benzophenone was synthesized through a condensation reaction of benzoic acid and phloroglucinol with an Eaton reagent as a catalyst. The percentage of the product was 60%, and it was characterized using FTIR and 1H-NMR. The sunscreen activity was carried out using a UV-Vis spectrophotometer to calculate the SPF value. The synthesis result was made in several concentration variations: 100, 150, 200, 250, and 300 ppm to measure the SPF values. The results showed that the SPF values were 9.89, 13.39, 17.83, 23.77, and 28.26, respectively. Based on this, it can be concluded that these compounds have biological activity as sunscreen and samples of 200-300 ppm are included in the ultra-category as sunscreen.
Co-Authors Anjartikasari, Nurul Ari Jamhari Pratama Baiq Nila Sariningsih Baiq Nurmayana Cahyani, Ni Wayan Chyntia Pramesti Devy Febriana Dewi Fitri Nur’afuddin Dhoni Hermanto DIAN LESTARI Emmy Yuani Emmy Yuanita Emmy Yuanita Emmy Yuanita Emmy Yuanita Emmy Yuanita Emmy Yuanita Ernidasari Rohmati Erwin Jayadi Putra Eryani, Farica Haviz, Nur Vinna Hayani, Hafiyatul Hermawati, Elvira I MADE SUDARMA Ima Arum Lestarini Inda Noviani Inggit Garnasih Ira Agustina Isnaini Iwan Sumarlan Jufrizal Syahri Kadek Yefta Christian Lalu Dimas Pratama Atmaja Made Ganesh Darmayanti Maria Ulfa Maria Ulfa Maria Ulfa Maria Ulfa Maria Ulfa Maulida Septiyana Muhammad Suprodi Suprodi Ni Ketut Santi Rahayu Ningsih, Baiq Nila Sari Nur Indrianingsih M.G Indrianingsih Nurlely Shabna Syundari Ratnasari, Baiq Desy Ridho Abdi Saputra RINA KURNIANINGSIH Rizkyani, Azizah Rohmana, Ainni Romel Hidayat Saprizal Hadisaputra Septiari, Wayan Uni Sirojuttolibin, Sirojuttolibin Siti Raudhatul Kamali Sri Seno Handayani Sudewianingsih, Ni Made Sudirman Sudirman Sudirman Sudirman Sudirman Sudirman Sudirman Sudirman Sudirman Sudirman Surya Hadi Surya Hadi Surya Hadi Tamara, Cynthia Claudia Taufan Hari Sugara Wahidatun, Wahidatun