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All Journal Jurnal Ilmu Pertanian VALENSI Jurnal Riset Kimia Indonesia Chimica Acta Science and Technology Indonesia Jurnal Penelitian Pendidikan IPA (JPPIPA) Indonesian Journal of Chemistry Jurnal Pengabdian Magister Pendidikan IPA jurnal Ilmu Pertanian (Agricultural Science) EIGEN MATHEMATICS JOURNAL Acta Chimica Asiana Jurnal Ilmiah Abdi Mas TPB Unram Jurnal Diferensial Jurnal Warta Desa (JWD) Journal of Fundamental Mathematics and Applications (JFMA) Jurnal Pendidikan dan Pengabdian Masyarakat Jurnal Pengabdian Inovasi Masyarakat Indonesia Molekul: Jurnal Ilmiah Kimia Jurnal Ilmu-Ilmu Pertanian
Tri Dharmayani, Ni Komang
Universitas Mataram
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Materials Science & Nanotechnology Mathematics Physics Public Health Social Sciences Other

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Sosialisasi Pemanfaatan Nira Aren Sebagai Bahan Baku Pembuatan Nata Kepada Masyarakat Desa Jurit Baru, Kabupaten Lombok Timur, NTB Ni Komang Tri Dharmayani; Surya Hadi; Emmy Yuanita; Maria Ulfa
Jurnal Pengabdian Inovasi Masyarakat Indonesia Vol. 2 No. 1 (2023): Edisi Februari
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (238.544 KB) | DOI: 10.29303/jpimi.v2i1.1978

Abstract

Desa Jurit Baru merupakan salah satu desa di kabupaten Lombok Timur yang memiliki hasil perkebunan berupa nira aren. Selama ini nira aren yang didapatkan belum dimanfaatkan secara optimal. Salah satu olahan nira aren yang dapat dijadikan bahan makanan adalah produk nata. Oleh sebab itu dilakukan suatu kegiatan sosialisasi melalui program pengabdian kepada masyarakat yang bertujuan meningkatan pengetahuan, sikap, dan keterampilan masyarakat Jurit Baru tentang pemanfaatan nira aren sebagai bahan baku pembuatan nata serta merangsang minat kewirausahaan peserta. Target khusus program ini berupa produk nata yang menggunakan nira aren sebagai bahan dasarnya. Kegiatan ini terdiri dari 3 tahapan yaitu: (1) penyuluhan mengenai pemahaman secara teoritis mengenai pengertian teknologi fermentasi pada pembuatannya; (2) praktik pembuatan nata dari nira aren; serta (3) pendampingan kegiatan produksi dan pengemasan. Kegiatan pelatihan dan pembinaan perlu dilakukan secara berkesinambungan untuk mencapai tujuan utama dari kegiatan ini yaitu meningkatkan perekonomian masyarakat.
Molecular Docking of Xanthone Derivatives as Therapeutic Agent for Covid-19 Emmy Yuanita; Sudirman Sudirman; Ni Komang Tri Dharmayani; Maria Ulfa; Saprizal Hadisaputra; Jufrizal Syahri
Molekul Vol 17 No 1 (2022)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2022.17.1.5600

Abstract

Covid-19 has caused more than 14 million confirmed cases and more than 6 hundred deaths as of 21 July 2020 globally. However, there is no approved drug to treat the disease. Xanthone is a potential therapeutic option for the virus that have been tested using molecular docking. There were 12 of xanthone compounds and its derivatives which have been docked against two protein crystals, 2GX4.pdb and 6FV1.pdb, which obtained two potential compounds of hydroxyxanthone derivatives with sulfonate and chloro substitution. These compounds are potentially developed into one of the agents for the treatment of infection COVID-19 disease. Based on energy data and interactions with amino acid residues when compared with its own native ligands, namely NOL and E8E, respectively. Energy docking and energy docking interactions are equal to - 43.3057and - 45.5805 Kcal/mol respectively, during interactions with amino acid residues in the form of Gly 142, His 163, Cys144, Glu166, Gln164 and His 41. Based on these two data, it can be concluded that trihydroxyxanthone compounds 4 and 8 with chloro and sulfonate substitution are very potential to be developed as drug agents for Covid-19 disease therapy through protease inhibition.
Profiling of Modified Chitosan-Based Composites as Tetracycline Hydrochloride Drug Release Systems Anjartikasari, Nurul; Yuanita, Emmy; Dharmayani, Ni Komang Tri; Sudirman, Sudirman; Sudewianingsih, Ni Made; Ulfa, Maria
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 17, No 1: June 2024
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70561/ica.v17i1.33590

Abstract

Controlled drug release systems (DRS) are a crucial technology in the medical field, and they continue to be developed today. Chitosan is useful in manufacturing-controlled drug release systems due to its non-toxic, biodegradable, and biocompatible properties. However, it has some limitations when it comes to its physical and mechanical properties. Combining chitosan with other materials, such as bacterial cellulose (BC), graphite (Gr), ZnO, and TiO2, can improve its mechanical properties and antibacterial activity. This study aims to synthesize Chi/BC/Gr/TiO2 and Chi/BC/Gr/ZnO composites as drug release systems. When tested with TCH, an antibiotic model, the drug release kinetics of the composite followed the Hixson-Crowell and Korsmeyer-Peppas kinetics models. Additional tests for physical and mechanical properties, as well as antibacterial activity, have also been conducted. Mechanical properties in terms of tensile strength and Young’s modulus in composites with adding Gr, TiO2, and ZnO have higher values than Chi/BC alone. Compared to positive control, both TCH-loaded composites show higher inhibition against S. aureus bacteria. Based on the results of this study, composite Chi/BC/Gr/TiO2 and Chi/BC/Gr/ZnO have potential applications as DRS such as wound dressing.
Modified Bacterial Cellulose-Based Composite Profile for Drug Release of Tetracycline Hydrochloride Cahyani, Ni Wayan Chyntia Pramesti; Yuanita, Emmy; Dharmayani, Ni Komang Tri; Sudirman, Sudirman; Sudewianingsih, Ni Made; Ulfa, Maria
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 10, No. 1, May 2024
Publisher : Syarif Hidayatullah State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v10i1.37663

Abstract

Bacterial cellulose (BC) is a biodegradable natural polymer with high mechanical strength and non-toxicity. This biopolymer is widely used as a candidate in biomedical fields, such as drug delivery, wound healing, and filtration systems. However, BC lacks antibacterial activity which limits its use in biomedical applications. So, modification of BC-based composite is required. This study aims to examine the effects of modifying BC-based composites with fillers such as graphite (G) and polyvinyl alcohol (PVA) on the release of tetracycline hydrochloride (TCH) drugs. Adding fillers to BC can alter its physical and mechanical properties, reducing its porosity and swelling rate in acidic and alkaline mediums. The drug release of TCH from modified BC-based composites follows the Korsmeyer-Peppas and Hixson-Crowell kinetics models. Adding filler and TCH antibiotic to the composite enhances its antibacterial activity against Staphylococcus aureus with a significant inhibition zone. The results of the inhibition zone show that composites have the potential to be applied in biomedical fields, especially in transdermal patches.
Sosialisasi Pengemasan Produk dengan Plastik Biodegradable Berbahan Selulosa dan Strategi Pemasarannya di Kelompok Wanita Tani Alummahat, Lendang Nangka, Lombok Timur, NTB Ningsih, Baiq Nila Sari; Ulfa, Maria; Yuanita, Emmy; Dharmayani, Ni Komang Tri; Septiyana, Maulida; Haviz, Nur Vinna; Hayani, Hafiyatul; Tamara, Cynthia Claudia; Septiari, Wayan Uni
Jurnal Pengabdian Inovasi Masyarakat Indonesia Vol. 3 No. 2 (2024): Edisi Agustus
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpimi.v3i2.6002

Abstract

Desa Lendang Nangka di Lombok Timur, NTB, yang termasuk dalam World Geopark UNESCO di lereng Gunung Rinjani, memiliki potensi besar dalam sektor pertanian. Namun, tantangan muncul dalam pengemasan produk pertanian yang belum ramah lingkungan. Kegiatan ini bertujuan meningkatkan nilai produk pertanian bagi kelompok Wanita Tani Alummahat melalui penggunaan kemasan ramah lingkungan berbahan selulosa dengan metode gelatinisasi dan pemasaran melalui e-commerce. Pelaksanaan kegiatan melibatkan transfer pengetahuan, teknologi, serta pembinaan dan pendampingan untuk memastikan peningkatan nilai ekonomi lokal secara berkelanjutan. Kegiatan meliputi penyuluhan, pelatihan praktis, dan pembentukan Kelompok Usaha Bersama (KUB) sebagai wadah pengembangan ide inovatif. Evaluasi menunjukkan peningkatan signifikan dalam pengetahuan dan keterampilan partisipan terkait pengemasan ramah lingkungan, serta antusiasme yang tinggi. Program ini berkontribusi pada pengembangan strategi pemasaran dan pengemasan yang berkelanjutan di tingkat desa, dengan harapan dapat memberikan dampak positif pada ekonomi masyarakat lokal.
Enhanced Methods for Synthesizing Hydroxyxanthone Using Eaton and ZnCl2 Catalyst with Microwave Irradiation Yuanita, Emmy; Eryani, Farica; Septiyana, Maulida; Lestarini, Ima Arum; Dharmayani, Ni Komang Tri; Sugara, Taufan Hari
Science and Technology Indonesia Vol. 10 No. 3 (2025): July
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.3.753-758

Abstract

The methods for synthesizing hydroxyxanthone compounds are continually advancing. Among these, microwave-assisted organic synthesis (MAOS) has emerged as a particularly advantageous technique due to its reduced reaction times, improved yields, and enhanced selectivity. This study reports the efficient synthesis of 3,7 dihydroxyxanthone through the reaction of 2,5-dihydroxybenzoate and resorcinol, using Eaton’s reagent and zinc chloride (ZnCl2) as catalyst under MAOS conditions. The structures of the resulting compounds were analyzed using Fourier-transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance (1H-NMR). The efficiency of the catalytic systems was evaluated based on the product yields. The Eaton reagent catalysis resulted in a 9.38% yield of a red solid, while the ZnCl2-catalyzed reaction produced a significantly higher yield of 23.07%, with the product appearing as an orange solid. These results demonstrate that Zn
Hydrophilic Surfaces Turning of Graphene Nano Platelets by 1,3,6-Trihydroxyxanthone: π–π Stacking Interaction Affair in 2-D Yuanita, Emmy; Sirojuttolibin, Sirojuttolibin; Dharmayani, Ni Komang Tri; Ulfa, Maria; Septiyana, Maulida; Sudirman, Sudirman
Indonesian Journal of Chemistry Vol 25, No 3 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.89894

Abstract

Graphene nanoplatelet (GNP) has a good potential to be developed as a drug carrier material. In this study, the interaction of GNP with one type of drug, namely 1,3,6-trihydroxyxanthone (THX), has been studied. The results of XRD analysis and FTIR uptake show an excellent interaction between THX and GNP through the π–π stacking channel. This interaction makes the GNP surface more polar and soluble in the aqueous media. THX-graphene shows physical and chemical stabilities, where THX can be released under specific and controlled conditions. The results of this study show the potential of utilizing graphene as a drug carrier material for more specific disease targets with a longer drug release time.
ABC Index Analysis: Physical Properties of Prenylated Xanthone Pratiwi, Lia Fitta; Mufarrihati, Ardelia; Dharmayani, Ni Komang Tri; Wardhana, I Gede Adhitya Wisnu
JURNAL DIFERENSIAL Vol 7 No 2 (2025): November 2025
Publisher : Program Studi Matematika, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jd.v7i2.20418

Abstract

Xanthone is a heterocyclic compound with various substituents (hydroxy, prenyl, geranyl, methoxy, halogens, and others). The presence of these substituents contributes to diverse biological activities, including anticancer, antidiabetic, and antioxidant properties. This study aims to optimize the design of xanthone derivatives through a mathematical approach using Chemical Topological Graphs (CTG) and the Atom-Bond Connectivity (ABC) index. A literature review was conducted to identify the physicochemical properties, biological activities, and molecular structures of compounds such as 1,7-dihydroxy-3-methoxy-2-(3-methylbut-2-enyl)xanthone (1), Gartanin (2), and Garcinon (3). These xanthone derivatives are distinguished by the number of prenyl substitutions on their core structures. Chemical graph theory is employed to represent molecular structures, with atoms represented as nodes and chemical bonds as edges. The ABC index is calculated based on the degree of connected atoms within the molecules and correlated with the compounds’ physicochemical properties and bioactivity. The ABC index values for compounds (1), (2), and (3) are 32.186, 43.987, and 51.744, respectively. These values indicate that an increase in prenyl substitutions leads to higher ABC index values, which correspond to decreased polarity, increased boiling points, and enhanced bioactivity and stability of the xanthone derivatives
Analisis Hubungan Nilai Indeks Zagreb dengan Titik Didih dan Kestabilan Senyawa Kerangka Dasar Calamenene Sabil, M. Ibnu; Miftahurrahman, Miftahurrahman; Wardhana, I Gede Adhitya Wisnu; Dharmayani, Ni Komang Tri
JURNAL DIFERENSIAL Vol 7 No 2 (2025): November 2025
Publisher : Program Studi Matematika, Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jd.v7i2.20431

Abstract

A new compound, dysoxyphenol, isolated from Dysoxylum densiflorum, has acalamenene-based framework. The structure of dysoxyphenol is classified as a sesquiterpene. Thisstudy discusses the relationship between Zagreb Index values and the physical properties andstability of two compounds: calamenene and dysoxyphenol. The Zagreb Index, consisting of thefirst and second indices, is used to measure the structural stability of a graph through the sum ofsquared vertex degrees. The objective of this analysis is to determine the Zagreb Index values forcalamenene and dysoxyphenol, to measure the boiling points and stability of the compounds. Thisanalysis was carried out by examining the structures of calamenene and dysoxyphenol. The obtainedstructures were then analyzed graphically. The results of this study show that the first and secondZagreb Index values for calamenene are 262 and 340, which are smaller compared to the first andsecond Zagreb Index values for dysoxyphenol, which are 264 and 350, respectively. This indicatesthat calamenene has a lower boiling point than dysoxyphenol and is more stable than dysoxyphenol.
PENGARUH ASAM HUMAT SEBAGAI PELENGKAP PUPUK PADA TANAMAN JAGUNG TERHADAP EFISIENSI PEMUPUKAN DI LAHAN KERING KEC. BAYAN KAB. LOMBOK UTARA NTB (THE INFLUENCE OF HUMIC ACID AS FERTILIZER SUPPLEMENT ON MAIZE PLANT TO FERTILIZING EFFICIENCY IN UNIRRIGATED LAN Hermanto, Dhoni; Tri Dharmayani, Ni Komang; Kurnianingsih, Rina; Kamali, Siti Raudhatul
Jurnal Ilmu-Ilmu Pertanian Vol. 16 No. 2 (2012): Desember
Publisher : Politeknik Pembangunan Pertanian Yogyakarta-Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

A study of the influence of humic acid as fertilizer supplement on maize plant to fertilizing efficiency in unirrigated land of Kec. Bayan Kab. Lombok Utara NTB was conducted. Agricultural land of Kec. Bayan has the physical properties of sandy texture, loose structure and reddish brown with neutral acidity (pH 6.97 at a depth of 0-20 cm and a pH of 6.8 at a depth of 21-40 cm). In addition, it has low nutrient level of soil (Corganic, N, P, K) at depths 0-20 cm and 21-40 cm respectively are 0.912% and 1.150%; 0.064% and 0.074%; 0.001% and 0.005 %; 0.290% and 0.310%. Application of humic acid as fertilizers supplement improved the availability of major and micronutrients and enhanced their uptake. The highest availability and uptake of N, P and K was found in addition of humic acid @ 20 kg ha-1 along with 100% recommended dose of fertilizers. Application of humic acid in soil showed increasing of plant growth (plant height, weight and nutritional value of corn). Fertilized N, P and K without humic acid was provided of fertilizing efficiency below 50 %. The most efficient dose for humic acid fertilizer is 20 kg ha-1 along with 150 kg ha-1 of urea, 200 kg ha-1 of SP36 and 50 kg ha-1 of KCl.
Co-Authors Anjartikasari, Nurul Ardana, Alfian Putra Ari Jamhari Pratama Baiq Nurmayana Budiana, Irwan Cahyani, Ni Wayan Chyntia Pramesti Devy Febriana Dewi Fitri Nur’afuddin Dhoni Hermanto DIAN LESTARI Emmy Yuani Emmy Yuanita Emmy Yuanita Emmy Yuanita Emmy Yuanita Emmy Yuanita Ernidasari Rohmati Erwin Jayadi Putra Eryani, Farica Haviz, Nur Vinna Hayani, Hafiyatul Hermanto, Dhoni Hermawati, Elvira Hidayat, Muhammad Ahsan I Gede Adhitya Wisnu Wardhana I MADE SUDARMA Ima Arum Lestarini Inggit Garnasih Ira Agustina Isnaini Iwan Sumarlan Jufrizal Syahri Kadek Yefta Christian Lalu Dimas Pratama Atmaja Lestari, Dia Luzianawati, Luzianawati Made Ganesh Darmayanti Maria Ulfa Maria Ulfa Maria Ulfa Maria Ulfa Maulida Septiyana Miftahurrahman, Miftahurrahman Mufarrihati, Ardelia Muhammad Suprodi Suprodi Ni Ketut Santi Rahayu Ningsih, Apriliya Ningsih, Baiq Nila Sari Noviani, Inda Nur Indrianingsih M.G Indrianingsih Nurlely Shabna Syundari Nursofia, Baiq Ike Pratiwi, Lia Fitta Putri, Baiq Yusmiar Aulia Putri, Syaftirridho Ramdhani, Restu Agung Ridho Abdi Saputra RINA KURNIANINGSIH Rizkyani, Azizah Romel Hidayat Sabil, M. Ibnu Saprizal Hadisaputra Sariningsih, Baiq Nila Septiari, Wayan Uni Sirojuttolibin, Sirojuttolibin Siti Raudhatul Kamali Sri Seno Handayani Sudewianingsih, Ni Made Sudirman Sudirman Sudirman Sudirman Sudirman Sudirman Sudirman Sudirman Sudirman Sukmaningrum, Afif Dwi Surya Hadi Surya Hadi Surya Hadi Tamara, Cynthia Claudia Taufan Hari Sugara Tsani, M. Khairul Wahidatun, Wahidatun