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All Journal Biomedical Journal of Indonesia Indonesian Journal of Obstetrics & Gynecology Science Andalas obstetrics and gynecology journal PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Jurnal Pengabdian Masyarakat: Humanity and Medicine Jurnal Jeumpa Indonesian Community Empowerment Journal Experimental Student Experiences Ranah Research : Journal of Multidisciplinary Research and Development Pharmaceutical Journal
Purnamasari, Septi
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POTENSI ANTIBAKTERI FRAKSI AKTIF DAUN ALPUKAT (PERSEA AMERICANA MILL) DALAM MENGHAMBAT PERTUMBUHAN BAKTERI SHIGELLA DYSENTERIAE Purnamasari, Septi; Inggarsih, Rara; Diba, Masayu Farah; Laeto, Arwan Bin; Arneldi, Devina Firya Yasmin; Khairunnisa, Athira
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 2 (2024): AGUSTUS 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i2.29982

Abstract

Diare masih menjadi masalah utama terutama pada kelompok umur balita dan anak-anak. World Health Organization (WHO) mendefinisikan diare sebagai kejadian buang air besar dengan konsistensi lebih cair dari biasanya dengan frekuensi tiga kali atau lebih dalam rentang waktu 24 jam. Shigella dysenteriae adalah bakteri anaerob fakultatif, non-motil, dan gram negatif yang menyebabkan diare parah dan penyakit disentri yang disebut shigellosis atau disentri basiler. merekomendasikan golongan fluoroquinolone seperti ciprofloxacin dan levofloxacin sebagai lini pertama untuk mengobati bakteri patogen. Namun, penggunaan fluoroquinolone terbatas dalam pengobatan infeksi tertentu karena telah dilaporkan beberapa kasus resistensi mikroba pada bakteri salmonella dan shigella. Alpukat (Persea americana Mill.) dikenal sebagai salah satu tumbuhan obat yang memiliki sifat antibakteri karena mengandung senyawa antibakteri seperti saponin, alkaloid, dan flavonoid dalam buah, biji, dan daunnya. Selain itu, daun alpukat juga mengandung polifenol, sementara buahnya mengandung tannin. Penelitian ini bertujuan untuk melihat efektivitas fraksi daun alpukat terhadap bakteri S. dysenteriae. Metode yang digunakan adalah difusi agar (Kirby-Bauer) dengan variasi konsentrasi larutan uji. Hasil penelitian diperoleh jenis fraksi yang aktif dari duan alpukat (Persea americana Mill.) dalam menghambat pertumbuhan S.dysenteriae adalah fraksi etil asetat. Golongan senyawa antibakteri yang terdapat dalam fraksi etil asetat daun alpukat adalah golongan alkaloid, flavonoid, steroid, tannin dan saponin. Konsentrasi hambat minimum (KHM) fraksi etil asetat dari daun alpukat adalah 250µg/ml dalam menghambat bakteri S.dysenteriae.
The Relationship Between Stress Level And Menstrual Cycle In Final Level Of Sriwijaya University Medical Education Batch 2019 Prasetya, Bagus Eko; Abadi, Adnan; Purnamasari, Septi
Andalas Obstetrics And Gynecology Journal Vol. 7 No. 1 (2023)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.7.1.267-273.2023

Abstract

Background: Menstruation is the discharge of blood and mucous tissue through the vaginafrom the uterus periodically every month with a span of 24-35 days. Menstruation can beaffected by stress. The burden of working on the final assignment coupled with learning thathas started to be done face to face makes students have to adjust to their daily habits. Thepurpose of this study was to find out whether there is a relationship between stress levels infinal year students of Sriwijaya University Medical Education class of 2019.Methods: This study uses a type of observational research, namely correlation analysis witha cross sectional approach. Data collection was carried out in October 2022 and obtained124 student data, then an analysis was carried out using the SPSS program and analyzedusing the Chi Square test.Results: From the results of the study, it was found that 124 respondents who experiencedmenstrual disorders were 47 (37.9%) while 77 (62.1%) experienced normal menstruation,then the most stress was severe stress, namely 43 (34.7). Then an analysis of the relationshipbetween stress and the menstrual cycle was carried out, the result was p = 0.009 / p <α(0.05), which means that there is a relationship between stress and the menstrual cycle.Conclusion: There is a relationship between stress levels and the menstrual cycle
Effect of Action and Active Compounds of Leaf Vocational Leaf (Tristania Whitiana Griff.) on Bacteria Shigella Dysenteriae Purnamasari, Septi; Joko Marwoto
Experimental Student Experiences Vol. 2 No. 2 (2023): April
Publisher : LPPM Institut Studi Islam Sunan Doe

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58330/ese.v1i4.200

Abstract

The purpose of this study was to determine the ability of the antibacterial activity of pelawan leaf fractions and active compounds against Shigella dysenteriae bacteria. This research includes in vitro laboratory experimental research. The subject of this research is the bacterium Shigella dysenteriae. The results showed that the MIC value of the n-hexane fraction against Shigella dysenteriae was 125 mg/ml and the MIC value of the active compound n-hexane fraction was 62.5 mg/ml. Determination of the class of active compounds from the purification of the n-hexane fraction of Pelawan leaves obtained flavonoid compounds. The concentration equivalence test showed that 1 mg/ml n-hexane fraction was equivalent to 0.004 mg/ml ampicillin against Shigella dysenteriae bacteria and 1 mg/ml active compound flavonoid was equivalent to 0.01 mg/ml ampicillin against Shigella dysenteriae bacteria. It can be concluded that the active fraction of n-hexane and its compounds have positive antibacterial effectiveness against Shigella dysenteriae bacteria.
Pemberdayaan kader dalam edukasi pemberian ASI dan menyusui pada ibu hamil di wilayah Ilir Barat II Kurniati, Ardesy Melizah; Aziz, Aryani; Oktharina, Eka Handayani; Purnamasari, Septi; Husin, Syarif; Puspitasari, Naila Nirmala; Faustina, Corinna; Salsabila, Putri
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 6 No 3 (2025): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V6I3.190

Abstract

Exclusive breastfeeding is essential for maternal and infant health, yet its coverage remains low in several regions. This community service activity aims to evaluate the effectiveness of community-based counseling in improving knowledge among Posyandu cadres and pregnant women. The activity involved 11 cadres and 32 pregnant women in Ilir Barat II using pretest, counseling, discussion, simulation, and post-test approaches. Results showed an increase in participants' knowledge scores, with the cadres' median pretest score improving from 12 (8–18) to 18 (14–19), and pregnant women’s scores rising from 8.6 (2–15) to 17 (13–20). The PRECEDE-PROCEED model was applied to identify predisposing factors through IPTEKS-based education, enabling through simulations, and reinforcing through cadre support. Community-based counseling proved effective in enhancing participants' knowledge, though the changes were not entirely significant. This program has the potential to be replicated in other areas to improve exclusive breastfeeding coverage in Indonesia.
Co-Authors Adnan Abadi, Adnan Amalia Anita Rahmiwati Ardesy Melizah Kurniati Arneldi, Devina Firya Yasmin Arwan Bin Laeto Aziz, Aryani Diba, Masayu Farah Eka Febri Zulissetiana Faustina, Corinna Haerawati Idris, Haerawati Heni Yusnita, Heni Inggarsih, Rara Irsan Saleh, Mgs. Joko Marwoto Kesuma, Putri Zalika Khairunnisa, Athira Khairunnisa, Tyas Citra Lestari, Uray Nurul Dwi Lusia Hayati, Lusia Martadiansyah, Abarham Nita Parisa Oktharina, Eka Handayani PATIYUS AGUSTIANSYAH, PATIYUS Prasetya, Bagus Eko Puspitasari, Naila Nirmala Putri Maya Sari RACHMAT HIDAYAT Rini Nindela, Rini Rizal Sanif Salsabila, Putri Syarif Husin Syifa Alkaf Vivin Mahdalena, Vivin Yulistiana, Sisca Zaen, Wildana Ilmia Uli El Nuha Zen Hafy Ziske Maritska