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Determination of Anthocyanin Levels in Saffron Flower (Crocus sativus L) Infusion with Differential pH Method Fitriyani, Fitriyani; Nugraha, Davit
Ad-Dawaa : Journal of Pharmacy Vol. 2 No. 1 (2024): Ad-Dawaa: Journal of Pharmacy (May 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v2i1.557

Saffron (Crocus sativus L), as an important herbal plant in medicine, cosmetics and ather health industries. Saffron (Crocus sativus L) is used in tradisional medicine to treat various types of diseases, including to trear chronic diseases such as asthma and artritis, also used to treat coughs and fevers. The saffron plant (Crocus sativus L) contains active compounds, namely, carotenoids, anthocyanins, vitamins (tiboflavin and thiamine), and minerals. The purpose of this study was to determine the levels of anthocyanins in saffron flowers (Crocus sativus L). anthocyanins are a group of pigments that cause a reddish color, found in water-soluble cell fluids. Anthocyanin compounds function as antioxidants and free radical scavengers, thus playing a role in preventing aging, cancer, and degenerative diseases. The results of data analysis show that all the average levels of steeping saffron flowers from each temperature are different, in other words the average levels of steeping levels of saffron flowers from each temperature there are significant differences.

OPTIMIZATION OF GELATIN CONCENTRATION IN TABLET WITH AFRICAN LEAF EXTRACT (Vernonia Amygdalina) Wahlanto, Panji; Yusuf, Anna L; Nugraha, Davit; Siti Rahmah KR; Dissya Alifia
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 4 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i4.1614

African plants, especially the leaves, are a type of medicinal plant used by the community. This African leaf contains active lavonoids that can be used to measure blood glucose levels. Tablet preparations have the advantage that they are easy to consume, so in this study African leaves (Vernonia Amygdalina) were made into tablets. The ratios of the binder used were 4%, 5%, and 6%. After obtaining the evaluation results, data analysis was performed using the Kruskal–Wallis SPSS statistical test with a confidence level of 95%. The evaluation results showed that the three formulations only fulfilled the respective requirements, namely for the angle of repose test between 16.6° - 21.3°, the granule thickening test of all formulations is below <20% and meets the requirements, the weight uniformity test has an average of 191-192 mg meeting the predetermined requirements, namely not more than 3 times with an average of 7.35 -7.36 mm and a thickness of mean + SD 0,47 the disintegration time test of all formulations stated that they met the requirements that had been determined that is not more than 15 minutes, the friability test only on formulation III which met the requirements to get a result of 0.54% in formulations I and II did not meet the specified requirements, the hardness test of all formulations did not meet the specified test requirements. Keywords: African leaf extract, gelatin, tablets.

Optimization of Carbopol 940 Coriander Leaf Extract Gel (Coriandrum sativum L): Analysis of Physical Properties : EFFECT OF CARBOPOL 940 CONCENTRATION ON PHYSICAL PROPERTIES OF CORIANDER LEAF EXTRACT GEL (CORIANDRUM SATIVUM L.) Nugraha, Davit; Yusuf, Anna; Rahmah KR, Siti; Wahlanto, Panji; Fawziah, Cindyvia
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1883

Topical gels are widely used because they are convenient to apply, easily absorbed, and have good stability. Carbopol 940 is one of the thickening agents often used in gel formulations because it can produce high viscosity at low concentrations and is compatible with various active ingredients. In gel formulation, the selection of Carbopol 940 concentration is very important to determine physical properties such as viscosity, pH, spreadability, and stability. Coriander leaves (Coriandrum sativum L.) contain bioactive compounds such as flavonoids, tannins, and saponins that have potential as antioxidants and antimicrobials. This study aims to examine the effect of Carbopol 940 concentration on the physical properties of gel containing coriander leaf extract by experimental method with variation of Carbopol 940 concentration in coriander leaf extract gel formulation. The physical properties of the gel, such as viscosity, pH, spreadability, and stability, were tested using physicochemical parameters to evaluate the effect of Carbopol concentration on the quality of the preparation. Coriander leaves (Coriandrum sativum L.) contain bioactive compounds such as flavonoids, tannins, and saponins that have potential as antioxidants and antimicrobials. The results showed that the concentration of Carbopol 940 significantly affected the physical properties of the gel, including viscosity, spreadability, and pH. The conclusion shows that the optimal formulation of Carbopol 940 can produce coriander leaf extract gel with physical properties that meet the requirements of topical drugs. Keywords: Gel, Coriander Leaf Extract, Formulation, Physical Properties Test

Hedonic Evaluation of Red Ginger Extract Gummy Candy as an Innovative Approach to Prevent Stunting in Children Under Five Heryani, Heni; Nugraha, Davit; Lestari, Lusi; Rahmah Kurnia, Siti; Yusuf, Anna L
Genius Journal Vol. 5 No. 2 (2024): GENIUS JOURNAL
Publisher : Inspirasi Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/gj.v5i2.425

Introduction: Stunting can have long-term impacts on children's health and development. Preventing stunting in children under five requires a comprehensive approach, including adequate and balanced nutritional intake. One of the natural ingredients commonly used in traditional medicine is red ginger (Zingiber officinale var. rubrum), which contains phytochemical compounds, vitamins, minerals, and fiber beneficial for maintaining vascular and digestive health. Gummy candy formulations have the advantage of high acceptability and appeal, particularly for children who find it difficult to consume medicine. Objective: This study aims to determine the level of preference for gummy candy made with red ginger extract as a strategy to prevent stunting in children under five. Method: The study employed an experimental design using a sensory hedonic test. The inclusion criteria included mothers with toddlers. A total of 20 participants were selected using an incidental sampling technique. Result: The findings indicated that participants showed a high level of preference for red ginger extract gummy candy. On average, the gummy candy was rated as highly appealing in terms of appearance, taste, aroma, and texture. Conclusion: Red ginger extract gummy candy has significant potential to be well-accepted by children under five. Further improvements are recommended, particularly in enhancing the gummy candy's appearance and incorporating more varied shapes to increase its appeal.

Hedonic Evaluation of Red Ginger Extract Gummy Candy as an Innovative Approach to Prevent Stunting in Children Under Five Heryani, Heni; Nugraha, Davit; Lestari, Lusi; Rahmah Kurnia, Siti; Yusuf, Anna L
Genius Journal Vol. 5 No. 2 (2024): GENIUS JOURNAL
Publisher : Inspirasi Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/gj.v5i2.425

Introduction: Stunting can have long-term impacts on children's health and development. Preventing stunting in children under five requires a comprehensive approach, including adequate and balanced nutritional intake. One of the natural ingredients commonly used in traditional medicine is red ginger (Zingiber officinale var. rubrum), which contains phytochemical compounds, vitamins, minerals, and fiber beneficial for maintaining vascular and digestive health. Gummy candy formulations have the advantage of high acceptability and appeal, particularly for children who find it difficult to consume medicine. Objective: This study aims to determine the level of preference for gummy candy made with red ginger extract as a strategy to prevent stunting in children under five. Method: The study employed an experimental design using a sensory hedonic test. The inclusion criteria included mothers with toddlers. A total of 20 participants were selected using an incidental sampling technique. Result: The findings indicated that participants showed a high level of preference for red ginger extract gummy candy. On average, the gummy candy was rated as highly appealing in terms of appearance, taste, aroma, and texture. Conclusion: Red ginger extract gummy candy has significant potential to be well-accepted by children under five. Further improvements are recommended, particularly in enhancing the gummy candy's appearance and incorporating more varied shapes to increase its appeal.

FORMULASI KRIM WAJAH EKSTRAK PELEPAH POHON AREN (Arenga pinnata Merr.) SEBAGAI ANTI ACNE Fauzi, Rizky Mohammad; Nugraha, Davit; Wahlanto, Panji
Jurnal Farmasi & Sains Indonesia Vol 5 No 2 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no2p26-31

Aren (Arenga pinnata Merr.) is a biological resource believed to have antioxidant abilities and is easily found throughout Indonesia. It is widely used by the populace, for example in midrib flour as a traditional medicine to relieve itching and scars on the skin. The purpose of this study was to determine whether the palm leaf extract (Arenga pinnata Merr.) could be formulated into cream preparations and was of good quality. The research method used is experimental by formulating the extract into three formulations, namely the extract concentration of 1%, 3%, 5%. Data analysis was performed using qualitative analysis including organoleptic test, homogeneity test, and quantitative analysis including pH test, dispersion test, adhesion test, viscosity and using one-way ANOVA statistics. The results of the analysis showed that there was no significant difference in the concentration of palm midrib cream in pH with a sig value of 0.542 (sig. > 0.05), a dispersion of 0.504 (sig. > 0.05) and a Adhesion of 0.717 (sig. > 0.05) gave > 0.05) and the viscosity meets the standard of good cream viscosity which is between (2000 - 50000 cps). Data analysis of the results showed that the three variations of extracts could be formulated into cream preparations and had quality standards for cream preparations that met the requirements, there was no effect of variations in the concentration of arene (Arenga pinnata Merr.) on the physical quality of cream preparations. The best wording is found in F2 (3%). Further research is expected to modify the formula for preservatives and fragrance additives, create new dosage forms such as lotions.

Study of Taurine Content in Energy Drink Powders: UV-Vis Spectrophotometric Method Ramdan, Siti Rahmah Kurnia; Athollah, Rifqi Nabil; Yusuf, Anna L; Nugraha, Davit; Wahlanto, Panji
INDOGENIUS Vol 4 No 2 (2025): INDOGENIUS
Publisher : Department of Publication of Inspirasi Elburhani Foundation Desa. Pamokolan, Kecamatan Cihaurbeuti, Kabupaten Ciamis, Provinsi Jawa Barat, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/igj.v4i2.593

Background and Objective: Energy drinks are commonly consumed as a fast and affordable solution to fatigue, especially among adolescents and young adults. However, public knowledge about their appropriate use and the health risks of excessive intake remains limited. Taurine (2-aminoethanesulfonic acid), a conditionally essential amino acid found in many energy drinks, contributes to several physiological functions. Excessive intake of taurine may adversely affect kidney function. Method: The method of this study using UV-Vis spectrophotometry. A 0.1% ninhydrin solution was used for qualitative testing, while UV-Vis spectrophotometry was employed for quantitative measurement. Proteins were precipitated using Carrez I and Carrez II reagents before analysis. Results: A purplish-blue color change in the qualitative test confirmed the presence of taurine. Quantitative analysis revealed taurine concentrations of 0.025% and 0.012% in the two samples. Conclusion: The results validate UV-Vis spectrophotometry as a practical and dependable technique for analyzing taurine, highlighting the importance of educating the public on the associated health risks of excessive consumption.

Evaluation of Waiting Time for Compounding Prescription Services at Tasik Farma Pharmacy, Tasikmalaya Daliah, Santi Riyanti; Nugraha, Davit; Aqidah, Erni Salimatul
Ad-Dawaa : Journal of Pharmacy Vol. 3 No. 1 (2025): Ad-Dawaa: Journal of Pharmacy (May 2025)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v3i1.869

Waiting time is the time that patients can be used by patients to wait in line to get health care facilities, either at the hospital or at the pharmacy. This is related to the standard of health services that provide quality and quality. Most of the services concluded are for healing the disease. Not only for healing the patient, but also providing satisfaction with good service to the patient, so that the patient not only gets healing from his illness, but also gets good service. According to the Minister of Health Regulation No. 73 of 2016 concerning the standards of pharmaceutical services in pharmacies, the waiting time for prescription services at the pharmacy is 15-30 minutes, which is explained in article 5, page 6, paragraph 1. The purpose of the study was to determine how long the waiting time is required by the pharmaceutical personnel at the Tasik Farma pharmacy in the service of making compounded prescriptions. The method of this study uses case analysis or problems that occur with the aim of understanding and knowing the problems in depth that occur with the incoming data prescriptions.

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