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All Journal Medula Juke Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Majalah Kesehatan FKUB Reswara: Jurnal Pengabdian Kepada Masyarakat JK Unila (Jurnal Kedokteran Universitas Lampung) Medic Nutricia : Jurnal Ilmu Kesehatan Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Essentia: Journal of Medical Practice and Research
Novita Carolia
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Journal : medula

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Uji Daya Hambat Solutio Belerang Terhadap Pertumbuhan Bakteri Propionibacterium acnes Secara In Vitro Rindu Bunga Putri; Novita Carolia; Ety Apriliana
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.97

Abstract

Acne Vulgaris is an inflammation of the polysebaseal follicles indicated by the appearance of blackheads, papules, pustules, cysts and nodules, which often occur mainly in the chest (15%), face (99%), and back (60%). In Indonesia around 95-100% of men and 83-85% of women aged 16-17 years suffer from acne. One of the microorganisms that cause acne vulgaris is Propionibacterium acnes bacteria which is a normal flora on the skin. In treatment, acne vulgaris wide-spectrum antibiotics have been commonly used as a treatment for acne, as the time goes by, it has been found there are increasement of Propionibacterium acnes resistance to antibiotics like erythromycin, clindamycin, and tetracycline. Sulfur has been widely used in anti-acne products which have an antibacterial function and can inhibit the growth of Propionibacterium acne as a cause of acne. This study aims to test sulfur solutio with concentrations that are often used in anti-acne products, namely 2-10% in inhibiting P.acne bacteria. This type of research is an experimental laboratory with a well method. Solutio sulfur is divided by various concentrations of 10%, 8%, 6%, 4%, and 2%, with K (-) is distilled water, and K (+) is a clindamycin gel antibiotic. The data is based on the results of the measurement of the inhibition zone formed and tested with One Way Anova. The results of this study indicate the diameter of the inhibition zone formed sequentially, namely: 12.70 mm, 10.55 mm, 7.70 mm, 5.80 mm, 4.67 mm, positive control of 30,075 mm and negative concentration of 0 mm (p value = 0,001). There is an antibacterial effect of sulfur solutio with a concentration of 10%, 8%, 6%, 4% and 2% against Propionibacterium acnes bacteria.
Hubungan Pemakaian Inhalasi Kortikosteroid Flutikason Dengan Kejadian Eksaserbasi Pada Pasien Penyakit Paru Obstruksi Kronik Di Rumah Sakit Umum Daerah Abdul Moeloek Provinsi Lampung Periode Tahun 2015-2017 Natasya Aurum Alifia Zaini; Novita Carolia; Anggraeni Janar Wulan
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.169

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease with irreversible condition. One of the treatmentusing fluticasone inhaled corticosteroids shows a significant improvement in lung function, reducing symptoms andreducing exacerbations. The purpose of this study was to determine the relationship of fluticasone corticosteroid inhalationwith the incidence of exacerbations in COPD patients at Abdul Moeloek Regional Hospital in the period 2015-2017 LampungProvince. This study was an observational study that used secondary data (medical records) of 102 patients who wereanalyzed the type of the drug they used with the occurrence of exacerbations they experienced. The results of the analysisin this study showed a significant correlation between the use of fluticasone inhaled corticosteroids and the exacerbationsin COPD patients at Abdul Moeloek Hospital in 2015-2017 with a p value of 0.049 (p <0.05).
Efektifitas Edukasi Self Management Terhadap Kontrol Tekanan Darah Pasien Hipertensi Zada Amalia Agatha Sari Zada Amalia Agatha Sari; Novita Carolia; Rasmi Zakiah Oktarlina; Suharmanto Suharmanto
Medula Vol 13 No 6 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i6.535

Abstract

Hypertension is a systolic blood pressure 140 mmHg or higher and a diastolic blood pressure 90 mmHg or higher.22 In 2020 WHO (Word Health Organization) reported that there were 1.13 billion cases of hypertension and has caused 9.4 million dead.22 At the United States, in 2017-2018 it was reported that 63% people over 60 years old suffered from hypertension with a higher percentage of women (66.8%) than men (58.5%).2 According to the 2018 RISKESDAS results patients with hypertension in the elderly amounted to 63.5%. Due to its high prevalence, hypertension is a major global health problem and the main cause of death and disability in the world every year.12 Treatment of hypertension is carried out for a long time so that the success of hypertension treatment is strongly influenced by self management of patients to adhere to the treatment, routinely checking blood pressure, increasing physical activity, reducing cunsumption of foods containing sodium.11 Self management of hypertension has an important role in effective control off blood pressure in patient with hypertension.3 One of the ways to increase knowledge related to the prevention and control of hypertension is through education.10 The education provided in the form of theoretical materials such as lectures, discussions, counseling, e-learning, and also practices such as workshops or training with various related topics. The materials provided is in the form of facts about hypertension such as definitions, signs and symptoms, risk factors, how to diagnose and treat them, normal blood pressure, hypertension prevention, complications, drug use, drug side effects, the importance of taking medication regulary, the importance of blood pressure checks periodically, diet, physical activity, relaxation techniques such as deep breathing, muscle relaxation, guided imagery.18
Pola Pengobatan Coronavirus Disease-19 (COVID-19) dengan Komorbiditas Tuberkulosis Paru Pada Pasien Rawat Inap RSUD Al-Ihsan Bandung Tahun 2020 Chanief Hassan Widjaja; Novita Carolia; Intanri Kurniati
Medula Vol 13 No 7 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i7.846

Abstract

Coronavirus disease-19 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and attacks the respiratory tract as its main target. Pulmonary tuberculosis (TB) is a disease with high incidence in Indonesia and transmitted through the respiratory tract and attacks lung organs same as COVID-19, allowing the possibility for co-infection of the two microorganisms simultaneously. The purpose of this study was to determine the pattern of treatment for COVID-19 and pulmonary TB at inpatient care facility Al-Ihsan Hospital Bandung. This study was an observational descriptive study with retrospective approach. The number of samples were 15 who had COVID-19 and pulmonary tuberculosis, taken from March until December 2020 at inpatient care facility Al-Ihsan Hospital Bandung. The sample taken using the total sampling technique, then analyzed using univariate test.There are five types of drugs found in this study, which is antibiotics, anti-tuberculosisdrugs, antivirals, corticosteroids, and vitamins. The types of antibiotics used were azithromycin (80%), levofloxacin (80%), ceftazidime (13.33%), ofloxacin (6.67%), and cefotaxime (6.67%). Anti-tuberculosis drugs with fixed dose combination (FDC) were given to 13 samples (86.67%). The types of antiviral drugs used were isoprinosine (80%), oseltamivir (13.33%), and chloroquine (6.67%). The types of corticosteroid drugs used were dexamethasone (33.33%) and bethametasone (6.67%). Types of vitamins used were vitamin C (100%), vitamin B6 (6.67%), vitamin D (73.33%), and zinc supplements (33.33%).
Analisis Faktor Risiko Terhadap Mortalitas Pasien Sepsis di Ruang Intensive Care Unit (ICU) RSUD DR. H. Abdul Moeloek Provinsi Lampung Tahun 2018-2021 Putri Grace Aiko Purba; Ari Wahyuni; Novita Carolia; Liana Sidharti
Medula Vol 16 No 2 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i2.1788

Abstract

Sepsis is an organ dysfunction due to dysregulation of infection response. It is characterized by cardinal inflammatory signs such as vasodilation, leukocyte accumulation, and increased microvascular permeability in tissues away from the site of infection. Sepsis is identified using clinical criteria, specifically the Sequential (Sepsis-Related) Organ Failure Assessment Score with ≥2 points. Sepsis is a leading cause of mortality in the Intensive Care Unit. Its mortality is triggered by several risk factors, including age, low Glasgow Coma Scale and Mean Arterial Pressure scores, and the presence of comorbidities. This study aims to analyze the relationship between these determinants and mortality among the Intensive Care Unit sepsis patients. This study used an observational analytic method with a cross-sectional approach. The subjects were sepsis patients in the Intensive Care Unit of RSUD DR. H. Abdul Moeloek Lampung in 2018-2021 who met the inclusion and exclusion criteria. The independent variables were age, Glasgow Coma Scale, Mean Arterial Pressure, and comorbidities, while the dependent variable was mortality. Samples were collected using total sampling technique. The results showed that age, Glasgow Coma Scale, Mean Arterial Pressure, and comorbid disease were significantly associated sepsis mortality, with p-values of 0.008, 0.029, 0.040, and 0.013, respectively. Thus, there is a relationship between age, Glasgow Coma Scale, Mean Arterial Pressure, and comorbid disease to the mortality among sepsis patients.
Analisis Faktor Prediksi Peningkatan Kontrol Glikemik Pada Pasien Diabetes Melitus Tipe 2 Di RSUD Abdul Moeloek Provinsi Lampung Periode Januari-Desember 2022 Yovani Tria Ananda; Intanri Kurniati; Novita Carolia; Putu Ristyaning Ayu Sangging
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1910

Abstract

The 2018 Basic Health Research report indicated that prevalence of Diabetes Mellitus (DM) in Indonesia increased to 8,3%. This rise was accompanied by an increase in obesity prevalence, a major risk factor for DM, from 14,8% in 20113 to 21,8% in 2018. These findings suggest that the number of individuals with DM in Indonesia is substantial and continues to grow annually. Data from Bandar Lampung City in 2021 showed that out of 6,467,624 individuals aged ≥15 years, approximately 198,046 (3%) were diagnosed with DM. This study aimed to analyze the association between predictive factors and glycemic control among patients with type 2 diabetes mellitus at Abdul Moeloek Hospital, Lampung Province, during January-December 2022. This research employed an observational study with a cross-sectional design. Secondary data were obtained from medical records of both inpatient and outpatient type 2 diabetes mellitus patients. Data analysis was performed using the Chi-Square test, with the Mann-Whitney test as an alternative. The result demonstrated significant associations between age at diagnosis (p=0,006), duration of Diabetes (p=0,012), body mass index (p=0,016), and comorbidities (p=0,020) with glycemic control. In conclusion, age at diagnosis, duration of disease, body mass index, and comorbid conditions were significantly associated with glycemic control among patients with type 2 diabetes mellitus receiving oral antidiabetic drugs and insulin therapy at Abdul Moeloek Hospital, Lampung Province, during January-December 2022.
Co-Authors Ade Marantika Afifah Rizqy Nurfaiza Alyzah Nabila Miranda Anggraeni Janar Wulan Ari Wahyuni Asep Sukohar Asnah Tarigan Aulia Agristika Chanief Hassan Widjaja Christopher P P Pandiangan Dewi Nurfiana Dheti Efrilia Dian Isti Angraini Dicky Auliansyah Dita Maulina Prabiwi Dwi Indria Anggraini Ebti Rizki Utami Efriyan Imantika Ety Apriliana Evan Christian Fakhmiyogi Fakhmiyogi Fragil Khoirul Basyar Gigih Setiawan Helmi Ismunandar Hendra Tarigan Sibero I Made Galih Fradiva Giantara Intanri Kurniati Jhons Fatriyadi Suwandi Liana Sidharti M. Ricky Ramadhian Merry Indah Sari Muhammad Mahardika Malik Muhammad Ricky Ramadhian Muhartono Muhartono Nanda Fitri Wardani Natasya Aurum Alifia Zaini Nisrina Talida Hasan Oktadoni Saputra Oktafany Oktafany Putri Grace Aiko Purba Rasmi Zakiah Oktarlina Restu Pemanggih Rika Lisiswanti Rindu Bunga Putri Sangging, Putu Ristyaning Ayu Suharmanto Sutarto Sutarto Sutarto Sutarto Syazili Mustofa TA Larasati Tias Adhe Setyaningrum Yovani Tria Ananda Zada Amalia Agatha Sari Zada Amalia Agatha Sari