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Journal : Medula

Uji Daya Hambat Solutio Belerang Terhadap Pertumbuhan Bakteri Propionibacterium acnes Secara In Vitro Rindu Bunga Putri; Novita Carolia; Ety Apriliana
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.97

Abstract

Acne Vulgaris is an inflammation of the polysebaseal follicles indicated by the appearance of blackheads, papules, pustules, cysts and nodules, which often occur mainly in the chest (15%), face (99%), and back (60%). In Indonesia around 95-100% of men and 83-85% of women aged 16-17 years suffer from acne. One of the microorganisms that cause acne vulgaris is Propionibacterium acnes bacteria which is a normal flora on the skin. In treatment, acne vulgaris wide-spectrum antibiotics have been commonly used as a treatment for acne, as the time goes by, it has been found there are increasement of Propionibacterium acnes resistance to antibiotics like erythromycin, clindamycin, and tetracycline. Sulfur has been widely used in anti-acne products which have an antibacterial function and can inhibit the growth of Propionibacterium acne as a cause of acne. This study aims to test sulfur solutio with concentrations that are often used in anti-acne products, namely 2-10% in inhibiting P.acne bacteria. This type of research is an experimental laboratory with a well method. Solutio sulfur is divided by various concentrations of 10%, 8%, 6%, 4%, and 2%, with K (-) is distilled water, and K (+) is a clindamycin gel antibiotic. The data is based on the results of the measurement of the inhibition zone formed and tested with One Way Anova. The results of this study indicate the diameter of the inhibition zone formed sequentially, namely: 12.70 mm, 10.55 mm, 7.70 mm, 5.80 mm, 4.67 mm, positive control of 30,075 mm and negative concentration of 0 mm (p value = 0,001). There is an antibacterial effect of sulfur solutio with a concentration of 10%, 8%, 6%, 4% and 2% against Propionibacterium acnes bacteria.
Hubungan Pemakaian Inhalasi Kortikosteroid Flutikason Dengan Kejadian Eksaserbasi Pada Pasien Penyakit Paru Obstruksi Kronik Di Rumah Sakit Umum Daerah Abdul Moeloek Provinsi Lampung Periode Tahun 2015-2017 Natasya Aurum Alifia Zaini; Novita Carolia; Anggraeni Janar Wulan
Medula Vol 10 No 3 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i3.169

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease with irreversible condition. One of the treatmentusing fluticasone inhaled corticosteroids shows a significant improvement in lung function, reducing symptoms andreducing exacerbations. The purpose of this study was to determine the relationship of fluticasone corticosteroid inhalationwith the incidence of exacerbations in COPD patients at Abdul Moeloek Regional Hospital in the period 2015-2017 LampungProvince. This study was an observational study that used secondary data (medical records) of 102 patients who wereanalyzed the type of the drug they used with the occurrence of exacerbations they experienced. The results of the analysisin this study showed a significant correlation between the use of fluticasone inhaled corticosteroids and the exacerbationsin COPD patients at Abdul Moeloek Hospital in 2015-2017 with a p value of 0.049 (p <0.05).
Efektifitas Edukasi Self Management Terhadap Kontrol Tekanan Darah Pasien Hipertensi Zada Amalia Agatha Sari Zada Amalia Agatha Sari; Novita Carolia; Rasmi Zakiah Oktarlina; Suharmanto Suharmanto
Medula Vol 13 No 6 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i6.535

Abstract

Hypertension is a systolic blood pressure 140 mmHg or higher and a diastolic blood pressure 90 mmHg or higher.22 In 2020 WHO (Word Health Organization) reported that there were 1.13 billion cases of hypertension and has caused 9.4 million dead.22 At the United States, in 2017-2018 it was reported that 63% people over 60 years old suffered from hypertension with a higher percentage of women (66.8%) than men (58.5%).2 According to the 2018 RISKESDAS results patients with hypertension in the elderly amounted to 63.5%. Due to its high prevalence, hypertension is a major global health problem and the main cause of death and disability in the world every year.12 Treatment of hypertension is carried out for a long time so that the success of hypertension treatment is strongly influenced by self management of patients to adhere to the treatment, routinely checking blood pressure, increasing physical activity, reducing cunsumption of foods containing sodium.11 Self management of hypertension has an important role in effective control off blood pressure in patient with hypertension.3 One of the ways to increase knowledge related to the prevention and control of hypertension is through education.10 The education provided in the form of theoretical materials such as lectures, discussions, counseling, e-learning, and also practices such as workshops or training with various related topics. The materials provided is in the form of facts about hypertension such as definitions, signs and symptoms, risk factors, how to diagnose and treat them, normal blood pressure, hypertension prevention, complications, drug use, drug side effects, the importance of taking medication regulary, the importance of blood pressure checks periodically, diet, physical activity, relaxation techniques such as deep breathing, muscle relaxation, guided imagery.18
Pola Pengobatan Coronavirus Disease-19 (COVID-19) dengan Komorbiditas Tuberkulosis Paru Pada Pasien Rawat Inap RSUD Al-Ihsan Bandung Tahun 2020 Chanief Hassan Widjaja; Novita Carolia; Intanri Kurniati
Medula Vol 13 No 7 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i7.846

Abstract

Coronavirus disease-19 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and attacks the respiratory tract as its main target. Pulmonary tuberculosis (TB) is a disease with high incidence in Indonesia and transmitted through the respiratory tract and attacks lung organs same as COVID-19, allowing the possibility for co-infection of the two microorganisms simultaneously. The purpose of this study was to determine the pattern of treatment for COVID-19 and pulmonary TB at inpatient care facility Al-Ihsan Hospital Bandung. This study was an observational descriptive study with retrospective approach. The number of samples were 15 who had COVID-19 and pulmonary tuberculosis, taken from March until December 2020 at inpatient care facility Al-Ihsan Hospital Bandung. The sample taken using the total sampling technique, then analyzed using univariate test.There are five types of drugs found in this study, which is antibiotics, anti-tuberculosisdrugs, antivirals, corticosteroids, and vitamins. The types of antibiotics used were azithromycin (80%), levofloxacin (80%), ceftazidime (13.33%), ofloxacin (6.67%), and cefotaxime (6.67%). Anti-tuberculosis drugs with fixed dose combination (FDC) were given to 13 samples (86.67%). The types of antiviral drugs used were isoprinosine (80%), oseltamivir (13.33%), and chloroquine (6.67%). The types of corticosteroid drugs used were dexamethasone (33.33%) and bethametasone (6.67%). Types of vitamins used were vitamin C (100%), vitamin B6 (6.67%), vitamin D (73.33%), and zinc supplements (33.33%).