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All Journal Buletin Udayana Mengabdi E-Jurnal Medika Udayana Biotropika WMJ (Warmadewa Medical Journal) Biology, Medicine, & Natural Product Chemistry Jurnal Penelitian Pendidikan IPA (JPPIPA) Meditory : The Journal of Medical Laboratory WICAKSANA: Jurnal Lingkungan dan Pembangunan Jurnal Kesehatan Indonesia Abdi: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Abdi Insani GANESHA MEDICINA Aesculapius Medical Journal Warmadewa Minesterium Medical Journal Community Services Journal (CSJ) Journal of Clinical Microbiology and Infectious Diseases Folia Medica Indonesiana Biodiversitas Journal of Biological Diversity
Indraningrat, Anak Agung Gede
Universitas Warmadewa
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences

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Evaluating Helminth to Treat Type 2 Diabetes – A Review Made Dharmesti Wijaya; Anak Agung Gede Indraningrat
WMJ (Warmadewa Medical Journal) Vol 4 No 1 (2019): May 2019
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.4.1.1042.21-29

Abstract

Type 2 diabetes (T2D) is characterized by lacking production of insulin and impaired insulin sensitivity. Despite the availability of antidiabetic drugs on the market, exploration of new therapeutic drugs for treating T2D from nature remains necessary. This review provides insights on the potential of helminths and helminth derived products to modulate immune response for treating T2D. We discussed several helminths that are under investigation in animal models for treating T2D namely Schistosoma mansoni, Nippostrongylus brasiliens, Litomosoides sigmodontis, and Strongyloides stercoralis. Finally, application of Schistosoma mansoni soluble egg antigens (SEA) in T2D treatment is also examined.
Jumlah Profil Pasien dengan Gaster Perforasi di RSUD Tabanan Tahun 2021-2022: - I Putu Gosen Partama; Made Kurniawan; I Gusti Ngurah Sumantri; Anak Agung Gede Indraningrat
WMJ (Warmadewa Medical Journal) Vol 10 No 2 (2025): November
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.10.2.9550.70-74

Abstract

Gastric perforation is a life-threatening surgical emergency that frequently arises as a complication of peptic ulcer disease and carries a high mortality rate. This study aimed to describe the clinical profile and outcomes of gastric perforation patients treated at Tabanan Hospital. A retrospective review of medical records was conducted for all gastric perforation cases from January 2021 to December 2022. Seventeen patients were identified. Most were older than 50 years (94%) and female (65%). More than half had no formal education and were unemployed. A history of nonsteroidal anti-inflammatory drug use was present in 59% of cases. Most patients arrived more than 6 hours after symptom onset, and many presented in critical condition, including shock (24%), tachypnea (76%), and acute kidney injury (53%). Intraoperatively, most perforations were located in the gastric antrum (65%) and measured 1–2 cm (82%). Postoperatively, hypoalbuminemia (94%), sepsis (35%), and pneumonia (24%) were common. The in-hospital mortality rate was 29%. In conclusion, gastric perforation at our institution predominantly affected elderly patients, with delayed presentation, severe initial clinical status, and high complication and mortality rates. Enhanced community awareness of ulcer symptoms, early referral, rational NSAID use, and timely surgical intervention are essential to improving outcomes.
PEMBERDAYAAN KELOMPOK IBU PKK DI DESA KERTA KECAMATAN PAYANGAN KABUPATEN GIANYAR BALI SEBAGAI PEMBANTU JUMANTIK UNTUK MENCEGAH INFEKSI DEMAM BERDARAH DENGUE Sri Masyeni; A.A.G Indraningrat; P.A Suryanditha; Agus Santosa
WICAKSANA: Jurnal Lingkungan dan Pembangunan Vol. 4 No. 1 (2020)
Publisher : Lembaga Penelitian, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wicaksana.4.1.2020.1-5

Abstract

Demam berdarah dengue (DBD) yang terjadi akibat infeksi virus Dengue merupakan penyakit yang mewabah tiap tahunnya di Bali dan Indonesia pada umumnya. Upaya menekan laju DBD khususnya melalui eradikasi vektor pembawa virus yaitu nyamuk Aedes aegypti perlu terus dilakukan dengan melibatkan peran serta masyarakat secara langsung. Penyuluhan mengenai DBD terhadap kelompok ibu PKK di Desa Kerta, Kecamatan Payangan, Kabupaten Gianyar, Provinsi Bali telah dilaksanakan dengan hasil yang memuaskan. Metode yang digunakan adalah presentasi dan diskusi melalui tatap muka. Hasil penyuluhan menunjukkan peningkatan pemahaman ibu-ibu PKK terhadap DBD dan upaya pencegahannya. Sebagai tindak lanjut kegiatan pengabdian ini, tim pembantu Jumantik dari anggota PKK Desa Kerta, Kecamatan Payangan telah dibentuk. Tim ini diharapkan berperan aktif dalam memonitoring dan meminimalisir tempat berkembang biak jentik nyamuk Aedes aegypti, serta secara aktif mensosialisasikan pencegahan DBD di lingkungan tempat tinggal mereka.
Pemberdayaan Kelompok Pecinta Karang Nuansa Pulau Nusa Penida Dalam Skrining Kesehatan Penyelam dan Budidaya Rumput Laut Anak Agung Gede Indraningrat; Made Dharmesti Wijaya; Ida Ayu Agung Idawati
WICAKSANA: Jurnal Lingkungan dan Pembangunan Vol. 7 No. 2 (2023)
Publisher : Lembaga Penelitian, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wicaksana.7.2.2023.45-53

Abstract

Kelompok pecinta karang Nuansa Pulau Nusa Penida merupakan kelompok yang dibentuk swadaya yang bertujuan untuk menjaga keasrian ekosistem terumbu karang di wilayah Desa Ped Nusa Penida. Kelompok ini berdiri untuk memberikan wadah bagi generasi muda di desa Ped untuk secara aktif berperan dalam upaya konservasi terumbu karang dan mengajarkan anggota keahlian bahari seperti menyelam dan diving. Keahlian bahari yang dimilik para anggota kelompok pencinta karang Nuansa tidak hanya berguna saat menjalankan kegiatan konservasi, tetapi juga memberikan benefit ekonomi bagi anggotanya sebagai guide diver maupun snorkeling. Hasil komunikasi dengan perwakilan kelompok pecinta karang memetakan permasalahan yang dihadapi mitra yaitu dari aspek kesehatan dan aspek ekonomi. Dari aspek kesehatan, mitra kurang memiliki pemahaman tentang pentingnya pengukuran awal kondisi tubuh sebelum menyelam seperti pengukuran tekanan darah, kadar oksigen terlarut dan gula darah. Sementara dari aspek ekonomi mitra berencana membudidayakan rumput laut untuk menambah pendapatan kelompok dan warga sekitar. Hanya saja mitra mengalami kendala karena tidak memiliki pengetahuan dan modal awal untuk memulai budidaya rumput laut. Beranjak dari permasalahan yang dihadapi mitra, program kemitraan masyarakat ini akan difokuskan untuk menyelesaikan masalah mitra dengan memberikan pengetahuan tentang penting pemeriksaan kondisi sebelum menyelam dan memfasilitasi dengan pemberian alat tensi serta alat cek gula serta kolesterol. Mitra juga telah mendapat pelatihan tentang budidaya rumput laut dan mendapatkan modal awal berupa bibit rumput laut Eucheuma cottonii untuk memulai tahapan budidaya rumput laut. Hasil PKM menunjukkan peningkatan pemahaman mitra berdasarkan pre dan posttest sebesar 60% tentang konsep skrining kesehatan pre-diving dan pemahaman mitra tentang cara budidaya rumput laut. Mitra merasa sangat terbantu dengan bantuan alat-alat pre-skrining berupa tensi meter, oximeter, alat deteksi glukosa, kolesterol dan asam urat. Setelah diberikan pemahaman tentang penting preskrining sebelum menyelam, mitra kini rutin memeriksa kondisi kesehatan anggotanya. Mitra juga telah menggunakan bantuan dana yang diberikan tim pengabdi untuk mulai membudidayakan rumput laut E. cottonii dalam skala kecil. Mitra membuat demplot budidaya rumput laut berukuran 3 x 5 m2 di lahan milik mereka sendiri secara gotong-royong anggota kelompok penyelam Nuansa Pulau. Hasil PKM ini diharapkan akan menjadi dasar bagi mitra untuk mengembangkan budidaya rumput laut dalam skala yang lebih besar dan meningkatkan kualitas kesehatan dan ekonomi para angota penyelam di masa yang akan datang.
Hubungan Kecemasan dengan Keluhan Premenstrual Syndrome (PMS) pada Mahasiswi di Fakultas Kedokteran dan Ilmu Kesehatan Universitas Warmadewa Tahun Angkatan 2020 Yunita Carolina Ero Atu; Putu Asih Primatanti; Anak Agung Gede Indraningrat
Aesculapius Medical Journal Vol 3 No 3 (2023): October
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.3.3.2023.414-418

Abstract

Menstruation is a natural process that occurs in every woman, which is a sign that the function ofthe reproductive organs has matured. Indications of premenstrual syndrome including physical,psychological and anxiety are the most common indications experienced by women when facingPMS. The purpose of the study was to determine the correlation between anxiety and premenstrualsyndrome (PMS) complaints that occurred in female students at the Faculty of Medicine andHealth Sciences at Warmadewa University, especially in the class of 2020. The type of research isanalytical observational, cross-sectional approach with a sample of 63 people. In this study, theresults obtained are the average majority of female students who have a tendency to anxiety with asevere category of 24 people or with a percentage of 38.1% and there is a frequency of 43 PMSfemale students or with a percentage of 68.3% where this shows the majority in the study. Theseare female respondents who complain of PMS. According to the results of the study, it can beconcluded that there is a correlation between anxiety and PMS complaints by students of theFaculty of Medicine and Health Sciences at Warmadewa University, especially in the class of2020 with a p value of < 0.05.
Hubungan BBLR dengan Stunting pada Anak Usia 2-5 Tahun di Desa Sidan Gianyar Tahun 2019 Putu Kania Ayu Kirana; Ni Putu Aniek Mahayani; Anak Agung Gede Indraningrat
Aesculapius Medical Journal Vol 3 No 3 (2023): October
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.3.3.2023.409-413

Abstract

Stunting is a condition that fails to grow in children under five so that the child becomes too short for his age. The standard stunting measurement is based on the body length index compared to age (PB / U) or height compared to age (TB / U) with a limit (z-score) less than -2 SD from the WHO child growth nutritional status table. Stunting events are influenced by several factors, one of which is Low Birth Weight (LBW). The purpose of this study was to find out if there is a LBW relationship with stunting events in children aged 2-5 years in Sidan Village of Health Center Gianyar I Working Area in 2019. This study is a analitic study with a case control approach. The sample in this study was all children aged 2-5 years in sidan village. This research sampling technique is a total sampling with a sample number of 58 respondents who meet the criteria of inclusion and exclusion. Data collection using observation sheets and mother and child health (KIA) books. Data analysis using the Chi-square test with α=0.05. In this study obtained the results: the frequency of stunting the most in the age range of 24-36 months as many as 12 children. Of the 58 children, there were 26 children with a history of LBW, including in the stunting group as many as 21 children and in the group of not stunting as many as 5 children. From this study, it was concluded that there is a historical relationship between LBW and stunting events in children aged 2-5 years in Sidan Village of Health Center Gianyar I Working Area in 2019 (p: 0.000; OR: 12,000; 95% CI: 3,569-44,488).
Hubungan Kejadian ISPA dengan Status Gizi pada Anak Balita Ni Ketut Devi Yogiswari; Kadek Ayu Lestari; Anak Agung Gede Indraningrat
Aesculapius Medical Journal Vol 4 No 1 (2024): February
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.4.1.2024.75-80

Abstract

Acute Respiratory Infection (ARI) is an acute infection in one or more parts of the respiratory tract starting from the nose to the alveolus, including the adnexa (sinuses, middle ear cavity and pleura), where the indications appear for a maximum of 10 days. ARI is a major cause of morbidity and mortality in developing countries, especially children under five. The high prevalence of ARI among toddlers is suspected to be correlated with their nutritional status. This study aims to analyze the correlation of nutritional status with the incidence of acute respiratory infections that attack children under five years, especially 12-59 months in UPT Kesmas Tegalalang II Gianyar during 2019. The study applied a cross sectional analytical approach that took secondary data in the form of 84 records. medical records for children under five at UPT Kesmas Tegalalang II Gianyar in 2019. The medical record data for toddlers was analyzed univariately to see the percentage of the frequency and proportion of each variable and bivariately with chi-square testing to see the effect of nutritional status on ARI cases where the significance value of p <0.05 . The data collected shows that there are 73 children under five with mild ARI (86.9%) and 11 people with moderate-severe ARI (13.1%). Meanwhile, children under five with poor nutritional status were 8 people (9.5%), poor nutritional status 23 people (27.4), good nutritional status 47 people (56%) and over nutritional status 6 people (7.1). %). The results of the bivariate analysis showed a significant correlation between ARI on the nutritional status of children under five (p value = 0.005). This study concluded that there was a significant relationship between ARI and the nutritional status of children under five at the UPT Kesmas Tegalalang II, Gianyar Regency in 2019.
Hubungan Tingkat Stres dengan Kecenderungan Gangguan Makan pada Mahasiswa Fakultas Kedokteran dan Ilmu Kesehatan Universitas Warmadewa I Gusti Made Arya Janardana Kepakisan; Putu Asih Primatanti; Anak Agung Gede Indraningrat
Aesculapius Medical Journal Vol 4 No 1 (2024): February
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.4.1.2024.94-101

Abstract

[The Relationship between Stress Levels and Eating Disorder Tendencies in Students at the Faculty of Medicine and Health Sciences, Warmadewa University] Stress is the body's response towards changes that caused regulatory response, physical, psychological and emotional adaptation. In students, particularly medical students who are categorized in the young adult age group, stress often occurs due to internal and external factors. Stress was thought to cause eating disorder. Eating disorder could cause pressures to one's life, and as such could present a serious health problem to a person. The purpose of this study was to determine the relationship between stress level and the tendency of eating disorder in medical students of Faculty of Medicine and Health Sciences Warmadewa University. One hundreds and twenty four respondents were selected using simple random sampling and met inclusion and exclusion criteria. Information from respondents were obtained by sending questionnaires online. Data obtained from this study was analysed statistically using univariate and bivariate methods. Bivariate analysis were performed using Kruskal-Wallis test with α<0.05. Among 124 respondents, 48 people experienced different stress levels whether it is mild, moderate, heavy or severe. In addition, 17 people experienced the tendency of eating disorder. The result of the bivariate analysis showed a significant relationship between stress level and the tendency of eating disorder (p value = 0,001). This study concluded that there is a significant relationship between stress level and the tendency of eating disorder among medical students of Warmadewa University
Skrining Aktivitas Antibakteri Bacillus sp. PCAR1 dari Rumput Laut Eucheuma spinosum terhadap Bakteri Staphylococcus aureus Ni Made Alit Yulianti; Anak Agung Gede Indraningrat; Ni Wayan Widhidewi
Aesculapius Medical Journal Vol 4 No 2 (2024): June
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.4.2.2024.165-171

Abstract

[Antibacterial Activity Screening of Bacillus sp. PCAR1 from Seaweed Eucheuma spinosum against Staphylococcus aureus bacteria] Microorganisms associated with marine organisms have the potential to produce secondary metabolite compounds with strong antibacterial activity. Previous research has isolated Bacillus sp. bacteria encoded as PCAR1 from Eucheuma spinosum seaweed with antibacterial potential against Gram-positive and Gram-negative bacteria. However, the potential bioactivity produced by bacillus sp. PCAR1, especially as an antibacterial against Staphylococcus aureus, still needs to be explored using chemical extraction method. In this research, a total of 100 mL of sterile NB liquid media containing the cell mass of Bacillus sp. PCAR1 was fermented for 5 days and then shaken at 150 rpm. The supernatant was separated from the cell mass by filtration using Whatman filter paper no.1.The filtrate was extracted using ethyl acetate pro-analytics (1:1 v/v). The extracts were analyzed for antibacterial activity using the Kirby-Bauer method, while the chemical composition of the extracts was analyzed using gas chromatography-mass spectrometry (GC/MS) method. Antibacterial screening of ethyl acetate extract of Bacillus sp. PCAR1 showed an inhibition zone of 6.23±0.06 mm against Staphylococcus aureus ATCC 25293, which is classified as moderate antibacterial activity. GC/MS analysis showed that the ethyl acetate extract contained 10 chemical compounds that have potential as antibacterial, with four dominant active compounds namely p-Xylene (7.26%), Ethanol, 2-butoxy (5.36%), o-Xylene (3.14%), and mesitylene (3.41%). Overall, these results provide an initial overview of antibacterial compounds that can be synthesized by Bacillus sp. PCAR1.
Skrining Aktivitas Antibakteri dan Antijamur dari Isolat Bakteri Marinobacter Hydrocarbonoclasticus NAR7 I Gusti Gde Agung Anantawikrama; Anak Agung Gede Indraningrat; Ni Wayan Widhidewi
Aesculapius Medical Journal Vol 4 No 3 (2024): October
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.4.3.2024.293-302

Abstract

Infectious diseases caused by bacteria and fungi are global health issues, including in Indonesia. Previous studies reported one bacterial isolate associated with the seaweed Caulerpa lentillifera, namely Marinobacter hydrocarbonoclasticus NAR7, which showed antibacterial activity against Streptococcus mutans based on the perpendicular streak method. This study is alaboratory research with a descriptive method. Isolate M. hydrocarbonoclasticus NAR7 was grown in 100 mL of nutrient broth supplemented with artificial seawater for seven days. The obtained supernatant was separated from the cell mass by filtration, and the supernatant was extracted with ethyl acetate at a ratio of 1:1 (v/v) and further evaporated at 40°C to obtain a thick extract. The crude ethyl acetate extract obtained was tested against Gram-positive bacteria (Staphylococcus aureus ATCC 25923, Streptococcus mutans FNCC 0405), and Gram-negative bacteria (Escherichia coli ATCC 25922, and Klebsiella pneumoniae ATCC 700603) using the Kirby-Bauer method. Screening results showed that the extract was only active against Staphylococcus aureus ATCC 25923 with an average inhibitory zone diameter of 7.32±0.57 mm, which is classified as moderate antibacterial activity. Meanwhile, the extract did not form inhibitory zone diameters against other test bacteria. Antifungal screening showed that the extract could not inhibit the growth of Candida albicans and Aspergillus flavus fungi. These results overall indicate the initial potential of antibacterial activity from the M. hydrocarbonoclasticus NAR7 isolate. Further optimization efforts, including extraction with different solvents, are required.
Co-Authors A.A. Made Semariyani Adhiputra, I Ketut Agus Indra Agus Santosa Alit Yulianti, Ni Made Amirah Khairunnisa Anak Agung Ayu Lila Paramasatiari Anak Agung Dewi Megawati Anak Agung Sri Agung Aryastuti AR, Sunthio Barran Cia Arta, Ni Kadek Dewi Asri Tiara Ayu Savitri Siskayani budiapsari, putu indah Choe, Daegeun Daegeun Choe Dewa Ayu Mas Maharani Dharmesti Wijaya Fridayanthi, Putu Utari HENY ARWATI I Gede Sutapa, I Gede I Gede Yoga Ayuning Kirtanayasa I Gusti Agung Ayu Sucitra Ekaryani I Gusti Gde Agung Anantawikrama I Gusti Made Arya Janardana Kepakisan I Gusti Ngurah Arjana I Gusti Ngurah Sumantri I Ketut Agus Indra Adhiputra I Made Sila Darmana I Putu Candra I Putu Candra Suta Adnyana I Putu Gosen Partama I Wayan Sudiarta I Wayan Sudiarta Ida Ayu Agung Idawati Ida Bagus Agung Dody Wira Putra Ida Bagus Gede Darmayasa Janurianti, Ni Made Defy Kadek Ayu Lestari Kadek Karang Agustina Kadek Lila Antara Kadek Suryawan Kirtanayasa, I Gede Yoga Ayuning Legis Ocktaviana Saputri Luh Putu Ardha Gangga Cendani Made Dharmesti Wijaya Made Kurniawan Maheswari, Ida Ayu Kartika Marta Setiabudy Marta Setiabudy Monika Febryanti Lebo Nuru Muhammad Amirul bin Abdul Rahman Mulyawan Made Bramastya Nugraha Teja Kusuma Natania, Evellyne Ni Kadek Widya Diari Ningsih Ni Ketut Devi Yogiswari Ni Made Alit Yulianti Ni Made Ayu Suardani Singapurwa Ni Made Utami Dwipayanti Ni Nyoman Sri Budayanti Ni Putu Aniek Mahayani, Ni Putu Aniek Ni Wayan Putri Primayanthi Ni Wayan Widhidewi P.A Suryanditha PA Suryandhita Pande Putu Christine Putri Purnami PANDE PUTU CHRISTINE PUTRI PURNAMI Prihantara, Komang Gede Yudha Purnami, Pande Putu Christine Putri Putri Herawati, Putri Putu Arya Suryanditha Putu Asih Primatanti Putu Austin Widyasari Wijaya Putu Kania Ayu Kirana Putu Shinta Widari Tirka Rahman, Muhammad Amirul bin Abdul Saputri Legis Ocktaviana Sri Masyeni, Dewa Ayu Putri Suryawan, Kadek Tanjung Subrata Udiyani, Desak Putu Citra Wahyu Antari Wijaya Wahyu Antari Wijaya Widowati, I Gusti Ayu Rai - Yan Ramona Yanti, Ni Komang Semara Yenni Ciawi YOES PRIJATNA DACHLAN Yunita Carolina Ero Atu