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All Journal JURNAL PENDIDIKAN TAMBUSAI Universitas Muhammadiyah Yogyakarta Undergraduate Conference Proceeding Hippocampus: Jurnal Pengabdian Kepada Masyarakat Hexagon Determinasi: Jurnal Penelitian Ekonomi Manajemen dan Akuntansi
Saputri, Dwi
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Agriculture, Biological Sciences & Forestry Humanities Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Control & Systems Engineering Economics, Econometrics & Finance Education Environmental Science Public Health Social Sciences Other

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Investigation of Moringa Leaf Compounds as Colon Anticancer Agents Using Bioinformatics and Molecular Docking Methods Saputri, Dwi; Kusumaningtyas, Triana; Setiadi, Prismo; Febriansah, Rifki
Proceedings of Universitas Muhammadiyah Yogyakarta Graduate Conference Vol. 2 No. 2 (2023): Strengthening Youth Potential for Sustainable Innovation
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/umygrace.v2i2.421

Abstract

Introduction - Colon cancer is a disease that has a high mortality rate. Cancer treatments such as chemotherapy can cause severe side effects. So, it is necessary to do research on herbal plants to minimize these side effects. The bioactive compounds in Moringa leaves (Moringa oleifera L.) are known to have antioxidant and anticancer activity, so they have the potential to be used as cancer treatment. Purpose – . This study aims to determine the potential of Moringa leaves as an anticancer agent in silico. Methodology/Approach – The in silico test used is STITCH-STRING bioinformatics and molecular docking. STITCH-STRING bioinformatics was used to determine the target protein of the test compound, and molecular docking was used to determine the binding affinity between the test compound and cancer protein. Findings – In the STITCH-STRING bioinformatics test, the potential targets for kaempferol and quercetin were TP53-ESR1 and STAT3-EGFR, respectively.test Molecular docking on cancer protein showed that quercetin compound in EGFR protein had the best binding with a docking score of -9.2 kcal/mol. This shows good results because the docking score obtained is lower than the comparison drug (Fluorouracil) which has a docking score of -4.2 kcal/mol. These results indicate that compounds in Moringa leaves (Moringa oleifera L.) have the potential to be used as anticancer agents. Originality/ Value/ Implication – Moringa leaf research using bioinformatics and molecular docking methods is still rarely done, so this research can be used as further knowledge related to the search for moringa leaf compounds that have the potential for anticancer using bioinformatics and molecular docking methods
ENVIRONMENTAL REVIEW INSTALASI PENGOLAHAN AIR LIMBAH (IPAL) KOMUNAL DI INDONESIA: STUDI KASUS IPAL KOMUNAL DI KABUPATEN SLEMAN YOGYAKARTA marendra, fajar; Saputri, Dwi; Prasetya, Agus; Yuliansyah, Ahmad Tawfiequrrahman
Hexagon Jurnal Teknik dan Sains Vol 5 No 2 (2024): HEXAGON - Edisi 10
Publisher : Fakultas Teknologi Lingkungan dan Mineral - Universitas Teknologi Sumbawa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36761/hexagon.v5i2.4157

Abstract

he communal domestic wastewater treatment plant (WWTP) in Distrik of Sleman, Yogyakarta built in 2006 and the latest in 2018. In this study, the assessment of six environmental aspects, quality of effluent, geographic location, land topography, receiving water bodies, floods hazard, and soil types, was carried out in the communal WWTP in the District of Sleman, Yogyakarta. Data collection techniques using Stratified Random Sampling combine with interview technic and field surveys, then an assessment is carried out based on the Likert scale. The results showed that the quality of effluent aspect gets an average score of 2.57, soil types (2.60), geographic location (2.83), land topography (3.13), receiving water bodies (3.17), and floods hazard (3.63). The quality of effluent aspect can improve by integrated with fixed bed process or electrochemical process. Overall, the environmental category of WWTP in the District of Sleman, Yogyakarta, gets an average score of 2.99 from the maximum value of 4 (quite a good).
PENGARUH POLA TIDUR, ASUPAN KAFEIN, DAN GANGGUAN EMOSI TERHADAP AKTIVITAS BELAJAR MAHASISWA UNIVERSITAS MUHAMMADIYAH SURAKARTA SAPUTRI, DWI; Muzakar Isa
Determinasi: Jurnal Penelitian Ekonomi Manajemen dan Akuntansi Vol. 2 No. 2 (2024)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/determinasi.v2i2.218

Abstract

This study aims to determine the influence of sleep patterns, caffeine consumption, and emotional disorders on the academic achievement of Muhammadiyah University of Surakarta (UMS) students. College students often face high levels of academic pressure, and factors such as caffeine consumption, irregular sleep, and emotional disturbances can affect their academic performance. This research uses a quantitative method with a survey method involving UMS students who are asked to fill out a questionnaire. This data will be analyzed using statistical techniques to determine the relationship between caffeine consumption, sleep patterns, emotional disorders and academic achievement. It is hoped that the research results will provide a better understanding of the factors that influence the quality of student learning and contribute to the development of time management strategies and student well-being in the university environment. Therefore, researchers hope that this research can provide a more comprehensive view of the factors that influence the academic achievement of UMS students and their implications for improving academic policies and services in higher education.
Meminimalisir Sampah Plastik Melalui Pemanfaatan Botol Bekas Sebagai Akuarium Perikanan di SD Negeri 22 Seladu Saputri, Dwi; Kusumawardani, Sagita; Febri, Febri; Yayan, Krisentia; Lugeri, Leo; Hanavi, Muhammad Ilham; Agam, Beryaldi; Urabi, Debby; Haq, Izhar Amirul; Jordi, Jordi; Kristiandi, Kiki; Sigiro, Oktavia Nurmawaty; Agusti, Evelin; Mahgfirah, Indria; Audina, Mia; Sangkala, Sangkala; Masara'T, Sudirman
Hippocampus: Jurnal Pengabdian Kepada Masyarakat Vol 4 No 1 (2025): Juni 2025
Publisher : PUSAT PENELITIAN DAN PENGABDIAN PADA MASYARAKAT (PPPM) POLITEKNIK NEGERI SAMBAS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47767/hippocampus.v4i1.1070

Abstract

Plastic waste is a serious environmental problem that requires immediate handling, especially in educational environments. SD Negeri 22 Seladu faces the challenge of managing plastic waste, especially used bottles, which have not been utilized optimally. This condition shows the need to increase students' awareness of plastic waste management and the provision of environmentally based learning media. This service activity aims to minimize plastic waste, increase students' understanding of waste management, and create learning media in the form of aquariums from used bottles. The method used includes preparation stages, delivery of materials, and practice of making aquariums from used plastic bottles. Activities are carried out with a participatory approach to actively involve students. The results of the activity show that students are able to understand the concept of recycling, increase creativity, and have a higher awareness of the importance of protecting the environment. This program provides significant educational and environmental benefits. By using used bottles as a learning medium, this activity can be used as a model for environmental education in other schools to support sustainable plastic waste management.
Analisis SWOT Peningkatan Daya Saing pada UMKM Keripik Telur Ketam Yasmine Snack di Kecamatan Membalong Belitung Arifin, Choirul; Saputri, Dwi; Komariah, Eti; Noviyanti, Indah
Jurnal Pendidikan Tambusai Vol. 8 No. 2 (2024)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sektor UMKM memiliki memang peran yang cukup besar dalam ekonomi Indonesia meskipun dalam bidang sumber daya manusia dan aset sering mengalami keterbatasan (Hermanto et al., 2016). Di Kabupaten Belitung, sektor UMKM berperan dalam industri pariwisata dan memberikan kontribusi positif terhadap ekonomi wilayah tersebut. Salah satu produk olahan makanan khas yang diminati oleh wisatawan adalah keripik telur kepiting, yang dihasilkan dari pengolahan kepiting dan telurnya. Penelitian ini dilaksanakan di daerah Kabupaten Belitung menggunakan metode penelitian pendekatan kualitatif dengan melakukan wawancara pada pemilik UMKM keripik telur kepiting yasmine snack dan melakukan observasi langsung di lokasi usaha. Selain itu, studi pustaka terkait industri keripik di daerah tersebut juga dilakukan untuk memperoleh pemahaman yang mendalam tentang konteks bisnis. Berdasarkan hasil penelitian dengan analisis SWOT dapat disimpulkan UMKM Keripik Telur Ketam Yasmine Snack memiliki beberapa kekuatan yang dapat dimanfaatkan, kelemahan yang perlu diperbaiki, ancaman atau kendala yang harus dihadapi, serta mungkin terdapatnya peluang yang bisa diambil dan dioptimalkan. Karena itu, sejumlah strategi perlu dikembangkan untuk meningkatkan daya saing UMKM ini.
Co-Authors Agam, Beryaldi Agus Prasetya Agusti, Evelin Ahmad Tawfiequrrahman Yuliansyah Arifin, Choirul Febri Febri Hanavi, Muhammad Ilham Haq, Izhar Amirul Jordi, Jordi Komariah, Eti Kristiandi, Kiki Kusumawardani, Sagita Lugeri, Leo Mahgfirah, Indria Marendra, Fajar Masara'T, Sudirman Mia Audina, Mia Muzakar Isa Noviyanti, Indah Rifki Febriansah Sangkala Setiadi, Prismo Sigiro, Oktavia Nurmawaty Triana Kusumaningtyas, Triana Urabi, Debby Yayan, Krisentia