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Analysis Of Maternal Risk Factor On Stunting In Children In Palembang City Pariyana; Iche Andriyani Liberty; Muhammad Aziz; Mariana; Machlery.AP; Kevin.S
International Journal of Science, Technology & Management Vol. 2 No. 3 (2021): May 2021
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v2i3.198

Abstract

The incidence of stunting is one of the sustainable development goals target. To achieve it, an intervention that is right and significant and in accordance with the priority of stunting risk factors. The priority of risk factors is influenced by many things in different places. Thus, this research is the key as a strategy in identifying priority factors as a prevention strategy against stunting toddlers in Palembang. This research is an analytical observational research with case control approach. The samples were collected using purposive sampling techniques and 170 research subjects were obtained. The data was collected from Health Centre of Palembang City by measuring the height according to the age of the toddlers and carried out interviews with the toddler’s mother. There results were analysed using Chi-square statistical tests. The analysis results obtained which had a meaningful relation with stunting incidence are maternal age, maternal work, maternal body height, maternal body weight, history of anemia during pregnancy, number of birth, pregnancy gap factor, history of iron or folate supplement consumption history, number of ANC visits, history of infectious diseases during pregnancy, and exclusive breastfeeding. The most dominant risk factors in sequence the chances of stunting children are the number of children more than one by 12 times, anemia during pregnancy by 9 times, mothers who have a high risk age has 7 times, the mother's height is not ideal by 6 times, the distance of pregnancy is equal to or less than 24 months by 4 times, an ANC visit is less than 4 times the chance of 4 times , do not give exclusive breast milk by 4 times, mothers who work outside the house by 3 times, do not consume iron or folate supplements by 3 times.
Analysis of Mortality Factors in COVID-19 Patients; Systematic Review Yunita Liana; Pariyana; Mariana
International Journal of Science, Technology & Management Vol. 2 No. 3 (2021): May 2021
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v2i3.201

Abstract

Abstract. Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. The increase in the number of COVID-19 cases is progressing quickly and has been spread between countries. As of October 14, 2020, there are 213 countries/regions around the world that have reported Covid-19 with a total of 38,002,699 confirmed cases of which 1,083,234 died. The purpose of this study was to determine the relationship between mortality factors and mortality in COVID-19 patients to predict the patient's prognosis. This research method is a systematic review through a literature review on mortality factors in COVID-19 patients Literature searches were accessed through internet searches using the Pubmed database based on the preferred reporting items for systemic review and meta-analysis (PRISMA). A systematic search was carried out on 18 October - 20 October 2020 with the keywords “COVID-19” AND “Death” OR “Decease” AND “Factor Associated”. There were 8 literature selected that met the inclusion and exclusion criteria. Based on the findings of the eight journals, mortality is old age, male, has a clinical condition of hypertension, obesity, diabetes, cardiovascular disease, lung disease, neurological disease, lymphophenia laboratory test results, hyperlactate dehydrogenase, increased procalcitonin, increased neutrophils, increased C-reactive protein, and increased D-dimer. All literature reported that a p value <0.05 was obtained from the analysis of the relationship between mortality factors and cases of death in COVID-19 patients. There is a significant relationship between mortality factors and the death of COVID-19 patients, where the mortality factors are elderly, male, have a clinical condition of hypertension, obesity, diabetes, cardiovascular disease, lung disease, neurological disease, lymphophenia laboratory test results, hyperlactate dehydrogenase, increase in procalcitonin, increase in neutrophils, increase in C-reactive protein, and increase in D-dimers in which the prognosis of patients who have mortality factors tends to be worse. Keywords: Mortality, Coronavirus, COVID-19
Gambaran Karakteristik Pengetahuan Masyarakat Awam Mengenai Penanganan Jenazah Pasien COVID-19 : Description of the Characteristics of General Public Knowledge Regarding the Handling of Corpses of COVID-19 Patients Mariatul Fadilah; Pariyana; Pramadita Widya Garini; Ully Febra Kusuma
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 4 No. 4 (2021)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (986.973 KB) | DOI: 10.56338/mppki.v4i4.1632

Abstract

Coronavirus diseases 2019 atau yang disingkat dengan COVID-19 telah menyita perhatian dunia sejak kemunculan pertamanya di Wuhan, China, pada akhir Desember 2019. Hal ini dikarenakan oleh penyebarannya yang cepat, sehingga pada 11 Maret 2020 WHO mendeklarasikan COVID-19 sebagai sebuah pandemi. Terhitung hingga tanggal 27 September 2020, WHO melaporkan terdapat 32.730.945 kasus terkonfirmasi COVID-19, dengan 991.224 jumlah kematian. Jumlah kumulatif kasus positif COVID-19 di Indonesia pada 27 September 2020 mencapai angka 275.213 dengan kasus meninggal sebanyak 10.386 kasus. Telah diketahui bahwa penyakit ini dapat ditularakan secara langsung dan tidak langsung. Hal ini menyebabkan banyak keresahan di dalam lingkungan masyarakat dan memunculkan stigma-stigma negatif terhadap proses pemulasaran jenazah pasien COVID-19. Oleh karena itu, penelitian ini dilakukan untuk melihat gambaran pengetahuan masyarakat awam mengenai pemulasaran jenazah pasien COVID-19. Penelitian ini menggunakan metode studi deskriptif observasional. Populasi pada penelitian ini adalah 88 orang masyarakat yang mengisi kuesioner penelitian daring/online. Dari 88 responden yang mengisi kuesioner secara lengkap didapatkan rerata usia 23,78 ± 7,46. Dari total 88 responden pada penelitian ini didapatkan rerata usia responden adalah 22,866,72 tahun. Mayoritas responden berjenis kelamin perempuan (63%), pendidikan terakhir perguruan tinggi (47,7%), dan mayoritas berstatus pelajar/mahasiswa (58%). Mayoritas responden memiliki pengetahuan baik, yaitu 39 orang (44,3%).
THE IMPACT OF RAD6 EXPRESSION ON CHEMORESISTANT OVARIAN CANCER: A SYSTEMATIC REVIEW Vernadesly, Leo; Nita Hertati; Pariyana
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 12 No. 1 (2025): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v12i1.477

Abstract

Chemotherapy is one of the modalities for treating ovarian cancer (OC), which is one of the most common reproductive organ cancers in women worldwide. Overexpression of RAD6 has been identified as a significant factor in chemoresistance in ovarian cancer patients. This systematic review aims to evaluate the relationship between RAD6 overexpression and chemoresistance in ovarian cancer. The databases used include PubMed, ProQuest, Science Direct, and Google Scholar, focusing on articles from the last 10 years. Out of 162 articles retrieved, only 4 met the selection criteria and were used in the analysis. The analysis results indicate that RAD6 overexpression is closely associated with increased resistance to chemotherapeutic agents, particularly platinum. The underlying mechanisms include enhanced DNA damage tolerance, increased proliferation, invasion, and the ability of cancer cells to develop stem-like phenotypes. These findings highlight RAD6 as a potential therapeutic target in preventing chemoresistance in OC. Further research is needed to develop specific RAD6 inhibitors that can be used in combination with conventional chemotherapy to improve treatment response and patient prognosis.
Peningkatan Pengetahuan dan Keterampilan Ibu Hamil pada Upaya Pencegahan Stunting di Puskesmas Gumawang OKU Timur RM. Aziz; Pariyana; Eddy Roflin; Hanna Marsinta Uli; Adira Sukmaningtyas; Naufal Fikri Ismail; Prima Yudha Aditya
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 6 No 2 (2025): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V6I2.173

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Stunting adalah kondisi gagal tumbuh pada anak di bawah lima tahun yang terjadi karena kekurangan gizi yang berkepanjangan dan seringnya mengalami infeksi, khususnya selama 1000 Hari Pertama Kehidupan (HPK), yang dimulai sejak kehamilan hingga usia 23 bulan. Stunting dapat memengaruhi perkembangan kognitif pada anak. Menurut Kementerian Kesehatan Republik Indonesia, angka stunting di Indonesia tahun 2021 mencapai 24%. Indonesia menargetkan angka stunting turun hingga 14 % pada tahun 2024. Kegiatan ini bertujuan untuk mengevaluasi efektivitas intervensi penyuluhan dengan melihat perubahan pengetahuan mengenai pencegahan stunting melalui pemenuhan kebutuhan nutrisi di Puskesmas Gumawang Kabupaten OKU Timur. Penyuluhan ini menggunakan presentasi PowerPoint dengan topik stunting yang terdiri dari gejala, dampak, dan pencegahan stunting, serta pemenuhan kebutuhan nutrisi ibu hamil. Kemudian, dilengkapi dengan sesi tanya jawab, serta pemeriksaan kesehatan gratis berupa pemeriksaan pengukuran berat badan, tinggi badan, tekanan darah, gula darah, dan kolesterol. Evaluasi pemahaman peserta melalui kuesioner mengenai stunting dan pemenuhan kebutuhan nutrisi dilakukan secara deskriptif.Edukasi yang diberikan efektif meningkatkan pengetahuan ibu hamil tentang pencegahan stunting, yang diharapkan dapat memengaruhi sikap dan perilaku mereka dalam menjaga status gizi selama kehamilan.
Upaya Optimalisasi Pengendalian Hipertensi Peserta BPJS Kesehatan Melalui Program Prolanis di Klub Prolanis Puskesmas Pakjo Kota Palembang Idris, Fachmi; Tjekyan, Suryadi; Pariyana; Liberty, Iche Andriyani
Khidmah Vol 6 No 1 (2024): Khidmah
Publisher : IKesT Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52523/khidmah.v6i1.500

Abstract

Salah satu penyakit tidak menular yang menjadi perhatian serius oleh pemerintah adalah hipertensi karena dapat menimbulkan komplikasi penyakit lain yang lebih berbahaya jika tidak dikelola dengan baik. Prevalensi hipertensi di Provinsi Sumatera Selatan sebesar 30,44%, untuk di kota Palembang sendiri mencapai 31,19% (Riskesdas, 2018). Kegiatan pengabdian masyarakat ini dilakukan pada selama 3 hari (tidak berurutan). Pada hari pertama kegiatan yang dilakukan adalah Focus Group Discussion yang dihadiri oleh tim pengmas serta petugas dari Puskesmas Pakjo yang membahas terkait pelaksanaan prolanis di Puskesmas Pakjo dan rencana jadwal selanjutnya. Pada hari kedua kegiatan yang dilakukan terdiri dari senam bersama, pemeriksaan kesehatan dan edukasi, penyuluhan mengenai prolanis dan hipertensi, dan pemberian hadiah. Kegiatan pada hari kedua ini diikuti oleh 40 orang peserta prolanis, tim pengmas, dan petugas Puskesmas Pakjo. Hasil dari kegiatan tersebut diantaranya adalah dari 40 peserta yang berpartisipasi 75% penderita hipertensi, 10% penderita diabetes melitus, dan 15% penderita hipertensi dan diabetes melitus serta terdapat peningkatan pengetahuan sesudah diberikan penyuluhan mengenai prolanis dan hipertensi. Pada hari ketiga, kegiatan yang dilakukan adalah home visit ke rumah pasien hipertensi yang tidak rutin memeriksakan diri ke Puskesmas Pakjo.
The efficacy of autologous serum therapy in chronic spontaneous urticaria: A systematic literature review and meta-analysis Suherman, Ahmad Ligar; Nopriyati; Pariyana
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 15, No 2, (2024)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol15.Iss2.art11

Abstract

Chronic spontaneous urticaria (CSU) is an autoimmune disease characterised by urtica lesions and/or angioedema accompanying an itching sensation, recurring for at least six weeks without any specific trigger. Autologous serum therapy (AST) is an adjuvant therapy for CSU that is resistant to H1 antihistamines. This therapy is an economical option in developing countries. There were a few studies discussing the role of AST in CSU. This systematic review and meta-analysis were conducted to evaluate the efficacy of AST based on urticaria activity scores (UAS or UAS7) and urticaria total severity scores (TSS) so that clinicians can consider them. Data were searched systematically in Cochrane, PubMed, Google Scholar, Willey, and EMBASE from 2000 to March 2023. Data analysis using Excel 2010 (Microsoft Corp) and MedCalc version 20.218. There were 14 studies: 4 randomised controlled trials (RCT), 9 prospective, and 1 cross-sectional. The average improvement in UAS and TSS scores at the end of therapy was 42.24% and 41.24%. Results of subgroup analysis of AST administration in the group autologous serum skin test (ASST) positive and ASST negative based on the end of therapy UAS score (p=0.18). Results of subgroup analysis of AST administration in the positive ASST and negative ASST groups based on the TSS score at the end of therapy (p=<0.001). Results of subgroup analysis of AST administration versus placebo based on TSS score (p=0.861). Based on subgroup analysis, autologous serum therapy improves TSS scores in CSU patients (ASST positive). However, AST is not significantly different from placebo.