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Journal : Indonesian Journal of Cancer

Intrapulmonary Mature Teratoma Presenting with Trichoptysis: A Rare Case Report Nidzarsyah, Muhammad Mirsa; Hidayat, Moulid; Lestari, Rina; Widiasari, Komang Sri Rahayu; Fathana, Prima Belia; Santosa, Hilda; Kumaladewi, Baiq Ratna; Restuningdyah, Novia Andansari Putri; Arsatt, Maz Isa Ansyori
Indonesian Journal of Cancer Vol 19, No 4 (2025): December
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i4.1390

Abstract

Introduction: Intrapulmonary teratomas (IPT) are exceptionally rare, with only a handful of cases reported worldwide. The disease may lead to severe outcomes, such as massive hemoptysis, airway compression, and malignant transformation. Several international case reports on IPT focus on the diagnosis and surgical treatment approach. In Indonesia, only one case of intrapulmonary teratoma has been documented and analyzed for its radiological characteristics and anatomical pathology. Here, we present a case of mature IPT treated with surgery and adjuvant chemotherapy. To the best of our knowledge, this case is the second to be reported in Indonesia.Case Presentation: A 28-year-old man presented with a complaint of hemoptysis accompanied by clumps of hair (trichoptysis). Physical examination revealed no abnormalities. Chest X-ray and computed tomography (CT) thorax with contrast showed a right lung mass. The patient underwent lobectomy excision with the postoperative CT scan showing a residual mass. Furthermore, pathological findings confirmed a mature teratoma. Patients were then treated with adjuvant chemotherapy and showed clinical improvement.Conclusions: This case emphasizes the importance of including IPT in the differential diagnosis of hemoptysis, especially when trichoptysis–a rare but distinct symptom–is present. Although imaging tests like contrast-enhanced CT scans are crucial for identifying intrapulmonary masses, histological analysis is necessary for a conclusive diagnosis. The mainstay of treatment persists in surgical removal, and adjuvant chemotherapy may help control any remaining illness. This case emphasizes the importance of early detection and a multidisciplinary approach to enhance patient outcomes because it is one of the few documented IPT cases in Indonesia.
Adrenocortical Carcinoma with Infiltrated and Ruptured Inferior Vena Cava in Adult Woman Maligan, Deden Jinar Wahyudi; Maulana, Akhada; Danurdoro, Aria; Santosa, Hilda; Kumaladewi, Baiq Ratna
Indonesian Journal of Cancer Vol 19, No 4 (2025): December
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i4.1355

Abstract

Introduction: Adrenocortical carcinoma (ACC) is a malignant tumor that develops in the adrenal cortex. This case involves a rare, aggressive disease that demands specialized knowledge and optimal treatment for a favorable prognosis. This study aims to present the case of a woman with a right-sided ACC extending into the inferior vena cava (IVC), managed through radical resection and IVC repair.Case Presentation: A 50-year-old female presented with a complaint of a lump in the upper right abdomen, which she noticed three months ago. Abdominal computed tomography (CT) scan with contrast revealed a solid, inhomogeneous mass in the right suprarenal region measuring 12 cm x 11 cm. However, three days before the scheduled operation, the patient was brought to the emergency department with complaints of weakness and muscle weakness throughout the body. During the surgery, an adrenalectomy on the right side revealed a tumor infiltrating the IVC, causing venous rupture. The histological examination of the right adrenal tissue revealed ACC, infiltration of tumor cells beyond the capsule, lymphovascular infiltration, and no evidence of tumor cell infiltration into the kidney tissue. The treatment approach for this ACC case involved a complete surgical resection with open adrenalectomy and vena reconstruction. Postoperative results indicated improved patient condition, including symptom relief and favorable biochemical evaluation after surgery.Conclusion: Our patient had a right-sided ACC with local vascular infiltration into the IVC.