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Journal : Jurnal Ilmiah Pharmacy

EFEKTIVITAS ANTIHIPERGLIKEMIK PADA KELINCI JANTAN DARI EKSTRA ETANOL BUNGA TELANG (Clitoria Ternatea) riana Versita; Nori Wirahmi; Nova Yustisia; Oky Hermansyah
Jurnal Ilmiah Pharmacy Vol 9, No 1 (2022)
Publisher : Sekolah Tinggi Kesehatan Al-Fatah Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52161/jiphar.v9i1.389

Abstract

Telang flower plant (Clitoria ternatea) is a leguminous plant belonging to the Fabaceae family, containing bioactive compounds that are useful for treatment. Its ability as a biologically active compound gives a great role to human interests. Phenolic compounds have a positive correlation with antioxidant activity, so that polyphenols are probably the compounds that have the most potential to contribute anti-radical activity in telang flower. Telang flower extract has many properties so it is used as a traditional medicine for several diseases. A number of studies have shown that flavonoids have antiviral, anti-allergic, antiplatelet, antidiabetic, diuretic, anti-inflammatory, antitumor, and antioxidant activities. The phytochemical content of telang flower which is efficacious as antidiabetic / antihyperglycemic is saponins and flavonoids. Based on this, a preliminary study was conducted to determine the effectiveness of ethanol extract of telang flower (Clitoria ternatea) against antihyperglycemic in male rabbits. This type of research is a laboratory experiment. Telang flower powder simplicia (Clitoria ternatea) was extracted using the maceration method. Telang flower (Clitoria ternatea) ethanol extract was made in 3 concentrations, namely 2%, 3% and 4%. Antohyperglycemic effectiveness test used 3 groups, namely negative control (without treatment), positive control (Glibenclamide), ethanol extract of telang flower (Clitoria ternatea) 2%, 3% and 4%, against 4 white rabbits weighing 3-3.5 kg and given sucrose, carried out until the 8th day. The data were statistically processed using One Way ANOVA (Analysis Of Variant). In conclusion, giving ethanol extract of telang flower (Clitoria ternatea) with concentrations of 2%, 3%, and 4% at 60 minutes gave an effective and significant reduction in blood glucose levels compared to negative control and positive control.
SKRINING FITOKIMIA METABOLIT SEKUNDER EKSTRAK ETIL ASETAT TANAMAN BANDOTAN (Ageratum Conyzoides L.) YANG DIAMBIL DARI PESISIR PANTAI PANJANG KOTA BENGKULU riana Versita
Jurnal Ilmiah Pharmacy Vol 9, No 2 (2022)
Publisher : Sekolah Tinggi Kesehatan Al-Fatah Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52161/jiphar.v9i2.428

Abstract

Tanaman Bandotan merupakan tanaman yang sering jumpai di perkarangan rumah, persawahan, perkebunan, pesisir pantai yang tumbuh liar oleh masyarakat sekitar sering dimanfaatkan sebagai obat herbal, untuk luka baik luka bakar ataupun luka sayat, karena kandungan dari senyawa metabolit sekunder yang dimiliki. Tujuan dilakukanya riset ini untuk mengetahui kandungan senyawa metabolit sekunder apa saja yang ada pada tumbuhan bandotan (Ageratum conyzoides L).”Metode yang digunakan adalah metode maserasi dengan pelarut etil asetat dan dilanjutkan dengan  menggunakan alat rotary evaporator untuk memperoleh hasil ekstraksi yang maksimal dan sampel di peroleh dari pesisir pantai panjang kota Bengkulu.”Hasil penelitian menunjukan bahwa tanaman bandotan yang di ekstraksi menggunakan etil asetat  mengadung senyawa alkaloid, triterpenoid, dan tanin. Kesimpulan pada penelitian ini adalah kandungan yang terdapat pada tumbuhan bandotan yang di ekstraksi menggunakan pelarut etil asetat  yaitu alkaloid, triterpenoid, dan tanin