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Endang Susilowati
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Journal : JRST (Jurnal Riset Sains dan Teknologi)

 1 
Eksplorasi Ekstrak Etanol Beberapa Tumbuhan Berpotensi Sebagai Antiketombe Ernanin Dyah Wijayanti; Endang Susilowati
JRST (Jurnal Riset Sains dan Teknologi) Volume 1 No. 2 September 2017: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (619.586 KB) | DOI: 10.30595/jrst.v1i2.1671

Abstract

Abstrak Ketombe merupakan salah satu masalah rambut yang disebabkan oleh fungi Malassezia furfur sehingga untuk pengendaliannya diperlukan agen antifungi. Beberapa tumbuhan telah digunakan secara empiris untuk terapi antiketombe antara lain: inggu (Ruta angustifolia), bambu tali (Gigantochloa apus), johar (Senna siamea), jintan hitam (Nigella sativa), apukat (Persea americana), dadap serep (Erythrina lithosprema), nagasari (Palaquium rostratum), pisang (Musa paradisiaca), sidaguri (Sida rhombifolia), tomat (Solanum lycopersicum), kethuk (Alocasia macrorrhiza) dan komak (Dolichos lablab). Penelitian ini bertujuan untuk membuktikan aktivitas antifungi ekstrak etanol tumbuhan uji dan menentukan nilai Kadar Hambat Minimum (KHM) dan Kadar Bunuh Minimumnya (KBM). Masing-masing simplisia tumbuhan uji diekstraksi dengan metode maserasi menggunakan pelarut etanol 70% selama 5 hari. Pengujian aktivitas antifungi terhadap Malassezia furfur menggunakan metode difusi sumuran, yang dilanjutkan dengan penentuan KHM dan KBM dengan metode dilusi. Hasil penelitian menunjukkan bahwa semua ekstrak etanol tumbuhan uji memiliki aktivitas antifungi yang bervariasi terhadap Malassezia furfur. Aktivitas yang kuat ditunjukkan oleh ekstrak etanol kulit buah pisang, daun bambu tali, daun komak, biji jintan hitam dan daun inggu. Nilai KHM masing-masing ekstrak antara lain: kulit buah pisang, daun bambu tali dan daun komak (10%), biji jintan hitam (20%), daun inggu (30%), daun dadap serep dan daun johar (50%), daun tomat (60%), daun apukat dan daun nagasari (70%). Ekstrak etanol daun sidaguri dan daun kethuk tidak memiliki nilai KHM. Semua ekstrak etanol tumbuhan uji tidak memiliki nilai Kadar Bunuh Minimum (KBM). Kata kunci: antifungi, ekstrak etanol, ketombe Abstract Dandruff is one of hair problem caused by Malassezia furfur, which can be controlled by antifungal agents. Empirically, some plants have been used as antidandruff treatment: rue (Ruta angustifolia), bamboo tali (Gigantochloa apus), blackwood cassia (Senna siamea), black cummin (Nigella sativa), avocado (Persea americana), Indian coral tree (Erythrina lithosprema), gutta percha (Palaquium rostratum), banana (Musa paradisiaca), cuban jute (Sida rhombifolia), tomato (Solanum lycopersicum), taro (Alocasia macrorrhiza) and lablab (Dolichos lablab). This research was aimed to observe antifungal activity, Minimum Inhibitory Concentration (MIC) and Minimum Fungicidal Concentration (MFC) of these 12 potential plants against Malassezia furfur. Each of plant simplisia was extracted by immersion in 70% ethanol  for 5 days. Antifungal activity assay against Malassezia furfur were conducted using agar well diffusion, followed by dilution method to determine MIC and MFC. The results showed that all of plant ethanolic extract have various antifungal activity against Malassezia furfur. Strong activity showed by banana peels extract, bamboo tali leaves extract, lablab leaves extract, black cumin seeds extract and rue leaves extract. MIC values obtained were 10 % for banana peels extract, bamboo tali and lablab leaves extract,  20% for black cumin seeds extract, 30% for rue leaves extract, 50% for Indian coral and blackwood cassia leaves extract, 60% for tomato leaves extract, 70% for avocado and gutta percha leaves extract. Whereas cuban jute and taro leaves extract did not show MIC values. All of plant ethanolic extracts did not show MFC values.  Key words: antifungal, dandruff, ethanolic extract
Co-Authors Ana Aryanti Andarini Permata Cahyaningtyas Ari Siswati Aris Wintolo Arum Meiranny Aryanti Musyarfah Atik Pujirahayu Atika Zahria Arisanti Dais Maesadillah Dina Lestari Elfi Susanti V. H. Ernanin Dyah Wijayanti Eva Nurhidayati Fatma Andini Fera Tiara Sari Firna Fhadianna Fitri Nur Shofa Hardiany, Dewi Hendra Rohman Herawati Himatul Khoeroh Holyness Nurdin Singadimedja Intan Tri Lestari Is Susiloningtyas Isna Muhammad Fathoni Iva Gamar Dian Pratiwi Kadarusmanto Kadarusmanto Khunelis Khunelis Kisty Syakilatih Fauzah Kuhnelis Laelatul Gorro M. Masykuri Maryam Maryam Maryam Maryam Maryam Maryani Maryani Melisa Melisa Muchammad Husni Mupliha Mupliha Nabila Salsabina Itha Ishmah Aurora Nadia Eka Khaerunnisa Nadya Indah Yohanita Nisa Nur Hayati Novrian Salwa Nunung Febriyaningsih Nur Sri Atik Nurhidayah Nurhidayah Nurlela Purnamasari purwadi purwadi Puspa Dwi Lestari Putri Marsanda R. Mendrika Vatosoa Idealy Rifa Ulfah Ghina Rita Sumiati Ningsih Riyanti Riyanti Rizha Yunia Lestari Dewi Rizka Ayu Halimatussyafaah Sentot Budi Rahardjo Sri Raharjo Saptono Putro Sri Retno Dwi Ariani Sri Setyowati Sri Sukarsi Sri Sukarsih Sukriyah Kustanti Moerad Surniah Surniah Surni’ah Surni’ah Thania Alfi Gina Insani tiara, Fera Tika Arniza Meidina Tyas Andreani Vivi Meitasari Widi Astuti Windiani Windiani Zaitun Na’im