Elfi Susanti V. H.
Bachelor Program Of Chemistry Education, Faculty Of Teacher Training And Education, Universitas Sebelas Maret, Indonesia Jl.Ir Sutami No 36 A, Surakarta, Central Java, Indonesia

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SYNTHESES AND ANTIOXIDANT ACTIVITIES OF SOME HYDROXY DIMETHOXY CHALCONE DERIVATIVES VH, Elfi Susanti
INDONESIAN JOURNAL OF PHARMACY Vol 25 No 1, 2014
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (467.23 KB) | DOI: 10.14499/indonesianjpharm25iss1pp17

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Four (4) hydroxy dimethoxy chalcones derivatives were synthesized by Claisen-Schmidt condensation of hydroxyacetophenone with 3,4-dimethoxybenzaldehyde using conventional method and grinding technique. The synthesized compounds were characterized by spectroscopy (IR, 1H-NMR and 13C-NMR). Synthesis of the hydroxy dimethoxy chalcone using grinding method is better than the conventional method. The synthesis using grinding method require a low concentration base, shorter reaction (15min) and higher yield (70-84%).  The antioxidant activity of the compounds was determined by DPPH method, showed that  2,5-dihydroxy-3,4-dimethoxy chalcone have the highest antioxidant activity.Key word: hydroxy dimethoxy chalcone, Claisen-Schmidt condensation, grinding, DPPH method
The Need Analysis of Module Development Based on Search, Solve, Create, and Share to Increase Generic Science Skills in Chemistry Nastiti, D.; Rahardjo, S. B.; VH, Elfi Susanti; Perdana, R.
Jurnal Pendidikan IPA Indonesia Vol 7, No 4 (2018): December 2018
Publisher : Program Studi Pendidikan IPA Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jpii.v7i4.12393

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Science generic skill is very important for students to solve every problem in learning processes and daily life. The purpose of this research was to explore the students’ needs of the chemistry module based on search, solve, create, and share (SSCS) to increase science generic skills. This research employed a descriptive qualitative method. There were 61 students in XI Grade from two Senior High Schools at Surakarta. The data were collected using questionnaires sheets, interviews, and materials analysis. The research revealed that the module and teaching materials used in the schools have not empowered the science generic skills maximally; also, the teachers remained to adopt discourse method which resulted in a teacher-centered learning. Such learning made the learning activities seemed monotonous, uninteresting, and less motivated the students in building concepts. Thus, the students required alternative teaching materials to increase their science generic skills. In sum, it is necessary to develop a chemistry module on the atomic structure which oriented to the SSCS.
PHYTOCHEMICAL SCREENING AND ANALYSIS POLYPHENOLIC ANTIOXIDANT ACTIVITY OF METHANOLIC EXTRACT OF WHITE DRAGON FRUIT (Hylocereus undatus) VH, Elfi Susanti; Utomo, Suryadi Budi; Syukri, Yandi; Redjeki, Tri
Indonesian Journal of Pharmacy Vol 23 No 1, 2012
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (233.544 KB) | DOI: 10.14499/indonesianjpharm23iss1pp60-64

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White dragon fruit  is  a well  known  and  widely  used  herbal medicine,  especially  in  Asia,  which  contains  several  interesting bioactive constituents and possesses health promoting properties. The  aim  of  this  study  was  to  analyze  for  the  bioactive compounds,  evaluate  total  phenolic  contents  and  antioxidant capacities  of  methanolic  extract  of  white  dragon  fruit.  The antioxidant  activity  was  determined  by  the  1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity assay. Total phenolic  content  were  determined  by  Folin-Ciocalteu  method. Phytochemical  screening  of  the  white  dragon  fruit  showed the  presence  of  triterpenoid,  alkaloid,  flavonoid  and  saponin. The  extract  exhibited  strong  antioxidant  activity  with  IC50 of 193 μg/mL, and total phenolic content of 246 μg/mL in 1 Kg dry extract.Key words: antioxidant activity, total phenolic, DPPH, white dragon fruit
Peran Keterampilan Berpikir Kritis Siswa di Sekolah Menengah Pertama pada Materi Sistem Pencernaan Juniar Fauziatul Azizah; Muzzazinah Muzzazinah; Elfi Susanti
SAP (Susunan Artikel Pendidikan) Vol 6, No 2 (2021)
Publisher : Universitas Indraprasta PGRI Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (295.905 KB) | DOI: 10.30998/sap.v6i2.10291

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Critical thinking skills are higher order thinking skills that should be developed in schools, in line with the objectives of the 2013 revised curriculum which prioritizes 21st century skills as a provision for future life. This study aims to analyze and classify the level of students in constructing critical thinking skills. The research1subjects1were 28 students of class VIII B SMP Negeri 6 Ngawi for the academic year 2020/2021. Data collection was carried out through interviews and critical thinking skills tests. The method used was descriptive qualitative. The critical thinking skills test instrument was 5 essay questions consisting of 5 indicators. The results of the critical thinking skills test were declared valid in terms of the1results1of1validation, level of difficulty, differentiation, and reliability. The analysis was carried out on the student test results on each indicator and categorized into five critical thinking categories consisting of very good (VG), good (G), medium (M), low (L), and very low (VL). The results1showed that1the highest percentage of indicators of critical thinking was obtained by 32% which were indicators of tactical strategy setting. Critical thinking indicators obtained by the lowest percentage of 8% were indicators of building basic skills. This proves that critical thinking skills need to be further trained so that they can be improved in science learning and advance in the field of education.
Strategi Peningkatan Daya Saing Kopi Liberika di Kabupaten Kepulauan Meranti Nurman Nurman; Elfi Susanti; Lintang Nur Agia
COSTING : Journal of Economic, Business and Accounting Vol 3 No 2 (2020): COSTING : Journal of Economic, Business and Accounting
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (292.783 KB) | DOI: 10.31539/costing.v3i2.1277

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Marketing management is one of the main activities carried out by the company to maintain the sustainability of the company, to develop, and to make a profit. The purpose of this study is to compare the traditional marketing system that is already running with the marketing partnership formed in aspects of marketing channels, marketing practices and marketing efficiency. The analysis used in this research is to use marketing margins. The results of this study indicate that there are three marketing channels available in the liberika coffee industry in the Meranti islands. Marketing practices so far have not been used by farmers, this can be seen from the profit margin obtained by large traders amounting to 1.47%. And from the efficiency of liberika coffee marketing is far from efficient because it has to go through a long process before reaching the final consumer. Keywords: Marketing Channels, Marketing Management, competitiveness
Improved Synthesis of 2',6'-Dihydroxy-3,4-dimethoxy Chalcone by Grinding Technique to Synthesize 5-Hydroxy-3',4'-dimethoxy Flavone Elfi Susanti VH; Sabirin Matsjeh; Mustofa Mustofa; Tutik Dwi Wahyuningsih
Indonesian Journal of Chemistry Vol 14, No 2 (2014)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (335.751 KB) | DOI: 10.22146/ijc.21255

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5-hydroxy-3',4'-dimethoxy flavone can be efficiently synthesized in two steps via the formation of 2',6'-dihydroxy-3,4-dimethoxy chalcone with good results. 2',6'-dihydroxy-3,4-dimethoxy chalcone as reactants for synthesis of flavones was prepared through Claisen-Schmidt condensation reaction between 2,6-dihydroxyacetophenones,3,4-dimethoxybenzaldehyde and solid NaOH in mortar for 15 min. The yield of the product (70%) is higher than conventional method (65%). This chalcone then oxidatively cyclized with iodine to form 5-hydroxy-3',4'-dimethoxy flavone (yield 62%). Compounds synthesized were characterized by spectroscopic (IR, 1H-NMR, and 13C-NMR).
SYNTHESIS, CHARACTERIZATION AND ANTIOXIDANT ACTIVITY OF 7-HYDROXY-3',4'-DIMETHOXYFLAVONE Elfi Susanti VH; Sabirin Matsjeh; Tutik Dwi Wahyuningsih; Mustofa Mustofa; Tri Redjeki
Indonesian Journal of Chemistry Vol 12, No 2 (2012)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (260.86 KB) | DOI: 10.22146/ijc.21355

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Synthesis of flavones and their derivatives has attracted considerable attention due to their significant pharmaceutical effects. 7-hydroxy-3',4'-dimethoxyflavone has been synthesized and its antioxidant activity has been investigated. Flavone was synthesized by oxidative cyclization of chalcone. 2',4'-dihydroxy-3,4-dimethoxychalcone was prepared by Claisen-Schmidt condensation of 2,4-dihydroxyacetophenones with 3,4-dimethoxybenzaldehydes in the presence of aqueous solution of sodium hydroxide and ethanol at room temperature. Oxidative cyclization of 2',4'-dihydroxy-3,4-dimethoxychalcone was done by using I2 catalyst in DMSO to form 7-hydroxy-3',4'-dimethoxyflavone. The synthesized compounds were characterized by means of their UV-Vis, IR, 1H-NMR and 13C-NMR spectral data. The compound was tested for their antioxidant activities by DPPH method.
ACTIVITY TEST OF GUAVA (Psidium guajava L.) LEAF METHANOL EXTRACT AS CONTRACEPTION ANTIFERTILITY TO WHITE MICE (Rattus norvegicus) Sri Retno Dwi Ariani; Endang Susilowati; Elfi Susanti VH; Setiyani Setiyani
Indonesian Journal of Chemistry Vol 8, No 2 (2008)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (412.846 KB) | DOI: 10.22146/ijc.21632

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The aim of this research is to know about if the guava (Psidium guajava L.) leaf methanol extract on 10.5 mg/mL and 21.0 mg/mL dossages indicate a positive test as contraception antifertility to white mice (Rattus norvegicus). The sample is guava leaf from Mungkid, Magelang Central of Java Indonesia. The animals experiment are the white mice on 140-300 g for female, 200-250 g for male and about 3 months of age in average. The steps of this research are : (1) preparing  sample, i.e. washing, drying on to indirect sunlight and make the sample into powder, (2) isolation the guava leaf powder in soxhlet instrument with hexane, (3) evaporation the sample with rotary evaporator until guava leaf hexane extract produced, (4) maseration the sample with methanol, (5) evaporation the sample with rotary evaporator until guava leaf methanol extract produced, (6) conducting contraception antifertility activity test to guave leaf methanol extract on 10.5 mg/mL and 21.0 mg/mL dossages to mice white. The results of this research are guava leaf methanol extract on 10.5 mg/mL and 21.0 mg/mL dossages indicate a negative contraception antifertility test to white mice but in these dossages have indicated that an antiimplantation effect (the total natality of fetus is less than the total implantation site in mice white).
Validitas Media Augmented Reality Berbasis Representasi Kimia Tetrahedral dengan Indeks Validasi Aiken Dwi Retno Sari; Sri Yamtinah; Sri Retno Dwi Ariani; Sulistyo Saputro; Elfi Susanti VH; Ari Syahidul Shidiq
Jurnal Penelitian Pendidikan IPA Vol 8 No 6 (2022): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v8i6.2333

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The development of science and technology has brought significant changes to the world of education, especially in the teaching and learning process. In the learning process, there is an interaction between teachers and students to transform their knowledge in the learning environment. To convey this knowledge, a supporting factor in learning is needed, namely learning media. This study aims to determine the feasibility of chemistry learning media in the form of augmented reality (AR) media based on chemical tetrahedral representations on thermochemical materials. This study uses quantitative research methods, with data processing and analysis using the Aiken model. The instrument used is a validation questionnaire sheet to determine the feasibility of the media. The feasibility test itself is carried out by testing 1 chemist, 1 learning media expert, 1 learning technology expert, and 6 education practitioners. The results of the validation test of the feasibility of augmented reality media get the results of Aiken's V 0.9899, ​​which means that the media is feasible to use. However, improvements still need to be made according to suggestions from the validator so that the finalized product can be used as a measuring tool that meets the criteria.
Pelatihan dan Pendampingan Produksi Minyak Atsiri Lempuyang Emprit (MALE) dan Hand Sanitizer Beradisi MALE serta Pemasaran Produk secara Digital pada UKM Herbal Suti Sehati di Kabupaten Sukoharjo Jawa Tengah Sri Retno Dwi Ariani; Sri Mulyani; Elfi Susanti VH; Suryadi Budi Utomo; Muhammad Hizbul Wathon; Anastasia Diaz Pramesti; Agustin Wulandari; Aufa Vib Mitsalina
Jurnal Abdi Masyarakat Indonesia Vol 3 No 4 (2023): JAMSI - Juli 2023
Publisher : CV Firmos

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54082/jamsi.802

Abstract

UKM Herbal Suti Sehati merupakan salah satu UKM di Jawa Tengah yang mampu bertahan walaupun terjadi pandemi Covid-19. Tujuan kegiatan ini adalah untuk menyelenggarakan pendampingan di bidang produksi, pengemasan, labelisasi, perhitungan analisis kelayakan usaha, dan tata cara pengurusan ijin edar produk minyak atsiri lempuyang emprit (MALE) dan hand sanitizer beradisi MALE, terhadap UKM Suti Sehati, serta pemasaran produk-produknya melalui digital marketing. Permasalahan yang dihadapi oleh UKM adalah: 1) UKM belum memiliki alat distilasi uap-air guna mengisolasi MALE, 2) UKM belum bisa memproduksi MALE dan hand sanitizer beradisi MALE, 3) UKM perlu pendampingan pemasaran produk-produknya melalui digital marketing. Solusi guna mengatasi permasalahan yang ada di UKM adalah, Tim P2M melaksanakan: 1) pemberian hibah alat distilasi uap-air, 2) pendampingan produksi, pengemasan, labelisasi, perhitungan analisis kelayakan usaha dan tata cara pengurusan perijinan usaha produk MALE dan hand sanitizer beradisi MALE, serta 3) memberikan pelatihan digital marketing. Hasil dari kegiatan pelatihan dan pendampingan produksi minyak atsiri lempuyang emprit (MALE) dan hand sanitizer beradisi MALE serta pemasaran produk secara digital terhadap UKM herbal Suti Sehati adalah terwujudnya pemanfaatan tanaman lempuyang emprit yang banyak tumbuh di lahan milik UKM, menambah jenis produk yang dihasilkan oleh UKM, dan peningkatan pendapatan UKM.
Co-Authors Adi, Yulia Kristi Agustin Wulandari Anastasia Diaz Pramesti Ari Syahidul Shidiq Ashadi, . Asna, Lilis Sofiyatul Aufa Vib Mitsalina Bayu Antrakusuma Catur Saputro, Agung Nugroho Dwi Retno Sari Endang Susilowati Endang Susilowati Fajar Rakhman Wibowo Hartantia, Restika Maulidina Iis Alviah Imam Sri Nugroho Juniar Fauziatul Azizah Lestari, Nova Dwi Lintang Nur Agia Luthfiana, Eva Magdalena, Octaviany Maria Ulfa Martini, Kus Sri Melati Kusuma Wardani Mohammad Masykuri Muhammad Hizbul Wathon Mulatsari, Desi Mulyani, Bakti Mulyani, Sri Mustofa Mustofa Muzzazinah Muzzazinah Nastiti, D. Ninda Dwi Cahya Devi Ningtyas, Arin Ika Nurma Yunita Indriyanti Nurman Perdana, R. Pramesthi, Hilda Nita Rahardjo, S. B. Rahmawati, Ani Ramandika, Muhammad Gunawan Dwi Redjeki, Tri Redjeki, Tri Redjeki, Tri Sabirin Matsjeh Safitri, Nadia Indri Salim, Eko Nur Samodra, Imam Saputro, Agung Nugroho Catur Saputro, Sulistyo Sastika, Agasta Ria Sentot Budi Raharjo Setiawan, Dwi Arief Setiyani Setiyani Setyowati, Widiastuti Agustina Eko Sri Mulyani Sri Mulyani Sri Mulyani Sri Retno Dwi Ariani Sri Retno Dwi Ariani Sri Retno Dwi Ariani Sri Retno Dwi Ariani Sri Retno Dwi Ariani Sri Yamtinah Sugiharto, Sugiharto Sulistyo Saputro Suryadi Budi Utomo Suryadi Budi Utomo Suryadi Budi Utomo Suryani, Adik Annisa Fitri Suryanto, Eko Tonang Dwi Ardyanto Totiana, Fian Tri Prianti Tri Redjeki Tutik Dwi Wahyuningsih Utami, Budi Utomo, Suryadi Budi Wathon, Muhammad Hizbul Widiastuti Agustina Eko Setyowati Wulandari, Lilis Yandi Syukri Zai, Fila Delfia Zulkarnaen, Rizmoon Nurul