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Thaib, Cut Masyithah
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PENGGUNAAN PATI KENTANG (Solanum tuberosum) LOKAL PREGELATINASI SEBAGAI BAHAN PENGEMBANG PADA TABLET PARASETAMOL GRANUL SECARA KEMPA LANGSUNG Dalimunthe, Agusmal; Thaib, Cut Masyithah; Silalahi, Yosy Cinthya Eriwaty; Tarigan, Mira Eka Diana Br
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Potatoes have a high nutritional content such as carbohydrates, starch, fat, protein, and water. Almost 90% of medicinal raw materials, both active substances and additives are obtained through imports and abroad, even though Indonesia's natural resources can be developed. This study aims to determine the effect of using pregelatinized local potato starch (Solanum tuberosum) as a developer in paracetamol tablets by direct compression. This research was conducted experimentally using five formulas with certain concentrations of F1 (4%), F2 (6%), F3 (8%), and F4 (10%). Then the tablet evaluation test was carried out, namely the weight uniformity test, tablet hardness test, tablet friability test, tablet disintegration time test. The results showed that the paracetamol tablets with local pregelatinized potato starch developer were made to meet the requirements for weight uniformity test, tablet hardness test, tablet friability test, and tablet disintegration time test. It can be concluded that local pregelatinized potato starch (Solanum tuberosum) can be used as a developer in paracetamol tablets.
PENENTUAN KADAR BESI DI DALAM AIR SUMUR GALI PENDUDUK DI DESA KAMPUNG LALANG SECARA SPEKTROFOTOMETRI SINAR TAMPAK Thaib, Cut Masyithah; Sinaga, Eka Margaret; Purba, Dina Riani
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2743

Abstract

Water is one of the sources of iron compound contaminants and the iron content in dug well water used as a water source is influenced by location and environment. The purpose of this study was to determine the iron content in dug well water used in daily life in the village of Kampung Lalang. Samples were taken from five different dug wells. Determination of iron content was carried out according to the spectrophotometric method in accordance with the procedures and spectrophotometers used in the chemical laboratory of the University of Sari Mutiara Indonesia. The results showed that of the 5 samples tested there were 2 samples containing iron compounds exceeding the levels of iron compounds set by the Ministry of Health of the Republic of Indonesia Number 907/MENKES/SK/VII/2002, the permissible levels of iron compounds, which should not be more than 0.3 mg/day. l. The iron content of 5 wells ranged from 0.2457 - 0.405 mg/l.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN SAMBUNG NYAWA (Gynura procumbens (Lour.)Merr.) TERHADAP BAKTERI Bacillus cereus ATCC 6633 Thaib, Cut Masyithah; Zuhairiah, Zuhairiah; Sianipar, Artha Yuliana; Simanullang, Eta M. Br
Jurnal Farmanesia Vol 6 No 1 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i1.2745

Abstract

Life-sustaining plants are plants that are widely used by people as natural medicines. Infectious disease is one of the problems in the health sector. Infection can be caused by various microorganisms, one of which is bacteria. This research was conducted at the Microbiology Laboratory, Sari Mutiara University, Indonesia. This study was conducted to examine the antibacterial activity of the ethanolic extract of life-sustaining leaves using the paper disc diffusion method with concentration variants of 20%, 30%, 40%, 50%, and 60% and used a negative control of DMSO and positive control of chloramphenicol. From the research that has been done, the extract of the continued life leaves has antibacterial inhibitory power. At a concentration of 20% (10 mm). At a concentration of 30% (11 mm). At a concentration of 40% (12.67 mm). At a concentration of 50% (13.3 mm). At a concentration of 60% (15.3 mm). It can be concluded that the ethanolic extract of the grafted life leaves has the highest antibacterial inhibition at a concentration of 60%, which is 15.3 mm.
FORMULASI SEDIAAN GEL MASKER WAJAH DARI BAHAN ALAM EKSTRAK RIMPANG TEMU MANGGA(Curcumaamada) Maringan, Maringan; Sitorus, Erly Nurita; Thaib, Cut Masyithah; Afrilla, Cut Windy
Jurnal Farmanesia Vol 6 No 2 (2019): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v6i2.2752

Abstract

Temu manggais a plantthat has a highantioxidant content. One type of antioxidant in temu manggais vitamin E which can rejuvenate the skin. There are manyuseful ingredients in the temu mangorhizome, namel ycurcumin, flavonoids, tannins, saponinsandes sential oils. This research method was carried out experimentally. The temu mangga rhizomewas extractedusing 70% ethanolsolventbymaceration method then concentrate dusing a rotary evaporator. The extractof temu mangga rhizome was then formulate dinto a gel maskwith a concentrationof F0 as a blank, using a base gel mask without extractand with the addition of F1 (1%) and F2 (3%) extracts. Evaluationof gel mask preparations includesorganoleptictests, namely observing with the five human sensessuch as odor, color, shape, pH test, homogeneity, dryingtimetest, irritationtest, and effectiveness test as a facial moisturizer using a skin analyzeron the facial skin of volunteers. Parameters measured include moisturecontent, poresize, and wrinkles. The resultsof this study indicate that the gel maskpreparation has a drying time of 20-30 minutes, isstablefor 4 weeks of storage anddoes not irritatethe skin. The measure mentresults of facial moisturizing activity showed that 3% extra gel mask was the best by increasing water content, shrinkingporeson facial skin and reducing wrinkleson the face
PENETAPAN KADAR FLAVONOID TOTAL EKSTRAK ETANOL JERAMI NANGKA (Artocarpus heterophyllus) SECARA SPEKTROFOTOMETRI-Visible Marpaung, Jon Kennedy; Nasution, Zuhairiah; Thaib, Cut Masyithah; Siringoringo, Junisan
Jurnal Farmanesia Vol 7 No 1 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i1.2766

Abstract

Flavonoids are compounds consisting of 15 carbon atoms which are generally distributed in the plant world. Flavonoid compounds are a group of the largest phenolic compounds found in nature, these compounds are red, purple, and blue dyes as well as yellow dyes found in plants. This study aims to determine the total flavonoid content of the jackfruit straw ethanol extract by using the UV-VIS spectrophotometric method, this study includes sample preparation, simplicia phytochemical screening, and extract manufacture, then determine the total flavonoid content of the jackfruit straw ethanol extract which is equivalent to quercetin (Quercetin). Equivalent (QE)) using aluminum chloride reagent with a wavelength of 437 nm by Visible spectrophotometry. Based on the research conducted, the total flavonoid content of jackfruit straw extract determined by Visible spectrophotometry using aluminum chloride reagent was 114.7590± 52.1263 mg QE/g extract.
ANALISIS MIKROBIOLOGI Escherichia coli JAJANAN MINUMAN DI SEKITAR JALAN KAPTEN MUSLIM KOTA MEDAN Maimunah, Siti; Sianipar, Artha Yuliana; Thaib, Cut Masyithah
Jurnal Farmanesia Vol 7 No 1 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i1.2767

Abstract

Escherichia coli is a gram-negative rod bacteria, not encapsulated and is a normal flora in the digestive tract of animals and humans that easily pollutes water. Escherichia coli can turn into an opportunist pathogen if it lives outside the intestine, for example in urinary tract infections, wound infections and mastitis. Drinks contaminated with microorganisms can cause health problems in the form of disturbances in the digestive tract with symptoms of nausea, heartburn, vomiting and diarrhea. The purpose of this study was to determine the presence of Escherichia coli bacterial contamination in snacks sold around the Kapten Muslimstreet. This descriptive study used 4 samples of iced drinks, namely young coconut ice, sugar cane ice, mixed ice and dawet ice. The sample testing technique uses the Most Probable Number (MPN) method. The media used in this study were lactose Broth, Brilliant Green Lactose Bile Broth, Eosin Methylene Blue Agar. This research was conducted at the Pharmacy Microbiology Laboratory, Sari Mutiara University, Indonesia. After the research, the results showed that 1 of 4 samples of snacks found on Jalan Captain Muslim was detected with Escherichia coli bacteria ranging from 2,800 cells/100 ml so that it was included in the poor criteria, in the category These snacks are not suitable for consumption and do not meet the criteria set out in the Indonesian Ministry of Health No.492/Menkes/Per/IV/2010 (Colifrom and Escherichia coli 0/100 ml).
PENENTUAN KADAR KAFEIN DALAM KOPI INSTAN SECARA SPEKTROFOTOMETRI ULTRAVIOLET Supartiningsih, Supartiningsih; Zuhairiah, Zuhairiah; Thaib, Cut Masyithah
Jurnal Farmanesia Vol 7 No 2 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i2.2778

Abstract

Caffeine in coffee has clinically beneficial pharmacological effects, such as stimulating the central nervous system, relieving fatigue, drowsiness and also increasing concentration. However, excessive use of caffeine can cause heart palpitations and stomach upset. According to SNI 01-7152-2006, the maximum limit of caffeine in food and beverages is 150 mg/day and 50 mg/serving. The purpose of this study was to determine the level of caffeine in instant coffee circulating in supermarkets in Medan City by Ultraviolet Spectrophotometry. Determination of caffeine content was carried out by the UV Spectrophotometry method after extraction using chloroform in an alkaline environment. The caffeine concentration can be calculated from the calibration curve regression equation. The results showed that the three instant coffee samples were determined to have different levels of caffeine, namely instant coffee sample code A 5.2585 mg/gram, code sample B 4.2348 mg/gram, and code C 133564. mg/gram. When viewed from the requirements, the caffeine content in the instant coffee samples coded A and B has exceeded the portion limit of 131.4625 mg and 84,768 mg, respectively, but is still within the limits set by SNI 01-7152-2006 if consumed in one pack. per day, henceforth the code C sample does not exceed the caffeine content limit of serving, which is 26.7128 mg of caffeine.
UJI KEAMANAN PRODUK TERHADAP KULIT DAN TINGKAT KESUKAAN REMAJA TERHADAP PRODUK KOSMETIK GEL PEMBERSIH WAJAH Sitorus, Elly Nurita; Thaib, Cut Masyithah; Sofwan, Ahmad Gazali
Jurnal Farmanesia Vol 8 No 1 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i1.2779

Abstract

Cosmetics are used on the external parts of the human body (epidermis, hair, nails, lips, and external genital organs) or on the teeth and oral mucosa mainly to clean, perfume, change appearance and/or improve body odor or protect and maintain the body in good condition. There are many types of fake cosmetics on the market today, there are cosmetics that are circulating in the market illegally (not having a BPOM permit) which are dangerous for users. This study aims to determine the level of preference for the use of several facial cleansing gel cosmetic products and to determine the effect of different active ingredients on the level of preference of several facial cleansing gel products. The sample used in this study were 30 female adolescents aged 15-23 years. The research method used in this research is descriptive method with data collection techniques in the form of questionnaires and observations. The results showed that all facial cleansing gel cosmetic products used in this study had passed the BPOM notification and did not experience irritation on the respondent's skin when the irritation test was carried out for 2 x 24 hours. At the level of preference for cosmetic products seen from the overall product parameters, the respondents most preferred were Brand A Products, which were 362, then Brand B Products were 356, then Brand C Products were 320.
HUBUNGAN PELAYANAN KEFARMASIAN TERHADAP KEPUASAN PASIEN PENGGUNA OBAT ANTI TUBERKULOSIS (OAT) DI UPT PUSKESMAS TITIPAPAN TAHUN 2021 Manurung, Kesaktian; Sinaga, Taruli Rohana; Thaib, Cut Masyithah; Monica, Yohana
Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i2.2789

Abstract

. Patient satisfaction is the match between expectations and the reality felt by the patient. Pharmaceutical service is a direct and responsible service to patients, related to pharmaceutical preparations with the aim of achieving definite results to improve the quality of life of patients. The purpose of this study was to determine the level of patient satisfaction at UPT Puskesmas Titipapan and to determine the relationship between pharmaceutical services and patient satisfaction at UPT Puskesmas Titipapan. The population in this study were OAT users who were treated at UPT Puskesmas Titipapan Medan during this study. With an average number of 31 patients per month. The number of samples in this study was determined using theformula in slovin order to obtain a sample of as many as respondents who visited the UPT Puskesmas Titipapan. This research is a descriptive research with quantitative methods. The type of approach used is a cross sectional design, namely a research design that collects data at one time to the sample. The results of this study were the level of patient satisfaction at the UPT Puskesmas Titipapan Medan, 71.0% of patients felt very satisfied. Of the 25 patients (80.6%) who received good service, 9 patients (29.0%) were satisfied. Based on the statistical analysis of these values indicate that the level of quality pharmaceutical services provided by the UPT Puskesmas TitipapanPengg Patients AgainstunaAnti- Tuberculosis Drugs (AOT) is less significant.
PENGGUNAAN EKSTRAK KELOPAK JANTUNG PISANG KEPOK (Musa acuminate L.) DALAM FORMULASI PEWARNA RAMBUT Thaib, Cut Masyithah; Fitri, Raissa; Nurbaya, Siti; Simatupang, Aprili Yanti
Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i2.2792

Abstract

Hair dye preparations are cosmetics used in hair makeup to color hair, either to restore the original hair color or change the original hair color to a new color. Kepok banana heart contains dyes and produces anthocyanins which are used as a safe food coloring. The purpose of this study was to determine that the leaf extract of the Kepok banana heart can be formulated as a hair dye and to determine the concentration of the banana flower extract that produces the best color. Kepok banana flower petals were extracted by maceration method using 96% ethanol, then concentrated to obtain Kepok banana flower petals extract. Hair dye preparations were made with a formula consisting of Kepok banana flower petals extract with various concentrations, namely: 2.5%, 5%, 7.5% and 10%. Staining is done by soaking for 1-4 hours. Observation of color stability was carried out by means of a stability test against 15 washings and exposure to the sun for 5 hours on colored hair, and a biological test (irritation). This study showed that the formula made with the extract of the petals of the Kepok banana heart can give a black color. The best staining was obtained from formula C, namely the extract of the petals of the banana heart of the Kepok banana with a concentration of 7.5% which produced a dark black color. The stability test for 15 washes and the stability test against the sunlight for 5 hours showed that there was no discoloration and no irritation to the skin. It can be concluded that Kepok banana flower petal extract can be used as hair dye.
Co-Authors Adiansyah Adiansyah, Adiansyah Afrilla, Cut Windy Al Munawarah, AL Anggraini, May Chandra, Devina Dalimunthe, Agusmal Dian Arisetya, Dian Eka Margareta Sinaga Eriwaty Silalahi, Yosy Cinthya Evarian Sembiring Fitri, Raissa Furqan, Mainal Haliza, Aipak Haloho, Mei Revolinda Helmi Helmi Hutasoit, Irmayanti Manurung, Kesaktian Marbun, Eva Diansari Maringan, Maringan Marpaung, Jhon Kennedy Marpaung, Jon Kenedy Marpaung, Jon Kennedy Monica Suryani Monica, Yohana Nasution, Pandapotan Nina Fentiana Nurita, Elly Purba, Dina Riani Purba, Elizabet Kristina Purwandari, Vivi Sapitri, Alfi Sarumaha, Vivid Angelina Sembiring, Jimmy Semsion Sianipar, Artha Yuliana Silitonga, Maringan Simanullang, Eta M. Br Simatupang, Aprili Yanti Sinaga, Taruli Rohana Sipayung, Inri Priskila Siringoringo, Junisan Siti Maimunah Siti Nurbaya Sitohang, Isra Kristina Sitorus, Elly Sitorus, Elly Nurita Sitorus, Erly Nurita Sofwan, Ahmad Gazali Sofwan, Ahmad Ghazali Supartiningsih - - Susanti, Julia Tarigan, Mira Eka Diana Br Yosy Cinthya Eriwaty Silalahi Zai, Andi Kristian Faatulo Zuhairiah Nasution, Zuhairiah