Article Per Year (5 Year)
p-Index From 2020 - 2025
3.323
P-Index
This Author published in this journals
All Journal BALI MEDICAL JOURNAL (BMJ) Medicina E-Jurnal Medika Udayana JBN (Jurnal Bedah Nasional) Majalah Kedokteran Andalas ISM (Intisari Sains Medis) : Jurnal Kedokteran Neurologico Spinale Medico Chirurgico Cermin Dunia Kedokteran Indonesian Journal of Cancer Eduvest - Journal of Universal Studies
Putu Anda Tusta Adiputra
Bedah Onkologi, Fakultas Kedokteran, Universitas Udayana
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences

Published : 44 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 44 Documents
Search

 1   2   3   4   5 
Faktor-faktor yang mempengaruhi kualitas hidup pasien kanker tiroid berdiferensiasi baik (DTC) paska tiroidektomi total di Rumah Sakit Umum Pusat (RSUP) Sanglah, Denpasar I Gusti Ngurah Gde Dwi Aryanata; I Wayan Sudarsa; Putu Anda Tusta Adiputra
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (470.83 KB) | DOI: 10.15562/ism.v10i1.379

Abstract

Background: Thyroid Cancer is the most common endocrine cancer. The majority of thyroid cancer (80-85%)  is well differentiated. Surgery is the treatment of choice for Well-Differentiated Thyroid Cancer (DTC). This research aims to evaluate the quality of life of patients with thyroid cancer who have undergone total thyroidectomy compared to the general population and also assess the influencing factors.Methods: This research includes 50 patients suffering from DTC after total thyroidectomy and 50 participants were selected to represent the general population who are then asked to fill out a detailed questionnaire EORTC QLQ 30 Indonesia Version including demographic data and clinical data as the TSH levels, the type of histopathology and interval of time since diagnosis, taken from the patient's medical record. Data were analyzed using independent t-test and linear regression in STATA 14 for windows.Results: It is evident that the quality of life of patients with DTC after total thyroidectomy is significantly lower compared to the general population (P<0.05). In addition, several factors such as age, educational level and income of the family give a strong influence as for gender, marital status, employment status, and the time interval since diagnosis gives a mild influence to the quality of life (P<0.05). However, TSH levels and type of histopathology was not proven to affect the quality of life (P>0.05)Conclusion: There are several factors related to quality of life among patients with DTC such as age, educational level and income of the family, gender, marital status, employment status, and the time interval since diagnosis
Gambaran tingkat pengetahuan tentang Periksa Payudara Sendiri (SADARI) pada mahasiswa Fakultas Kedokteran Universitas Udayana, Bali, Indonesia angkatan 2013-2015 Annisa Alviariza; Putu Anda Tusta Adiputra
Intisari Sains Medis Vol. 11 No. 1 (2020): (Available online: 1 April 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (213.857 KB) | DOI: 10.15562/ism.v11i1.531

Abstract

Background: BSE (Breast Self-Examination) is a systematic approach to inspection and palpation examination of the chest and armpit independently. BSE can be used as a means of early detection of breast cancer using a simple, inexpensive and safe. This study aims to determine the level of knowledge about BSE among students of Medical Education Faculty of Medicine Udayana University class of 2013, 2014 and 2015.Methods: A descriptive cross-sectional study was conducted among 285 respondents at Faculty of Medicine, Medical Education Program class of 2013, 2014, and 2015. The instrument used in this study was a valid and reliable questionnaire to identify the respondents' knowledge about breast cancer and BSE. Questionnaire data that has been collected is processed in the form of descriptive data analysis by calculating proportion and percentages. Data were analyzed using SPSS version 17 for Windows.Results: The highest average score about SADARI were obtained in Class 2013 (75%), followed by Class 2014 (72%), and Class 2015 (67%) students. A high level of knowledge criteria about SADARI also suggest similar results where Class 2013 was having the highest percentage (63%), followed by Class 2014 (25%), and Class 2015 (8%). However, based on the overall results, the students had a moderate score of 66%. Besides, according to the questions on the questionnaire, the students had an excellent average score about signs and symptoms (83%), cause (79%), and stage of breast cancer (79%).Conclusion: Class 2013 had a good level of knowledge regarding SADARI compared with Class 2014 and 2015. However, overall students still at a moderate average score of SADARI. Latar Belakang: SADARI (Periksa Payudara Sendiri) adalah metode sistematik untuk pemeriksaan inspeksi dan palpasi dada dan ketiak secara mandiri. SADARI dapat digunakan sebagai cara deteksi dini kanker payudara dengan menggunakan cara yang sederhana, murah dan aman. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan mengenai SADARI Mahasiswa Pendidikan Dokter Fakultas Kedokteran Universitas Udayana angkatan 2013, 2014 dan 2015.Metode: Sebuah studi potong lintang deskriptif dilakukan terhadap 285 responden di Fakultas Kedokteran, Program Pendidikan Kedokteran kelas 2013, 2014, dan 2015. Instrumen yang digunakan dalam penelitian ini adalah kuesioner yang sahih dan reliabel untuk mengidentifikasi pengetahuan responden tentang kanker payudara dan BSE. Data kuesioner yang telah dikumpulkan diolah dalam bentuk analisis data deskriptif dengan menghitung proporsi dan persentase. Data dianalisis menggunakan SPSS versi 17 untuk Windows.Hasil: Nilai rata-rata tertinggi tentang SADARI diperoleh pada siswa di Kelas 2013 (75%), diikuti oleh Kelas 2014 (72%), dan Kelas 2015 (67%). Kriteria tingkat pengetahuan tinggi tentang SADARI juga memberikan hasil yang serupa di mana Kelas 2013 memiliki persentase tertinggi (63%), diikuti oleh Kelas 2014 (25%), dan Kelas 2015 (8%). Namun, berdasarkan hasil keseluruhan, para siswa memiliki skor sedang 66%. Selain itu, menurut pertanyaan pada kuesioner, para siswa memiliki skor rata-rata yang sangat baik tentang tanda dan gejala (83%), penyebab (79%), dan stadium kanker payudara (79%).Kesimpulan: Kelas 2013 memiliki tingkat pengetahuan yang baik tentang SADARI dibandingkan dengan Kelas 2014 dan 2015. Namun, keseluruhan siswa masih berada pada skor rata-rata SADARI yang moderat.
The understanding of using universal precaution in medical student, ca-assistant and resident in the Faculty of Medicine, Universitas Udayana, Bali-Indonesia Tham Hong Yuan; I Wayan Niryana; Putu Anda Tusta Adiputra; Made Agus Dwianthara Sueta
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (293.484 KB) | DOI: 10.15562/ism.v11i2.688

Abstract

Introduction: This study was reported that among medical students, Co-Assistant (Co-Ass) and resident, several factors such as the academic overload in addition to the students’ non-school activities might contribute to this situation. There is a lack of universal precaution studies among Universitas Udayana students in Bali and in Sanglah Hospital. Thus, the aim of this descriptive study was to examine the understanding of using universal precaution among three categories of students as well as doctors in Universitas Udayana.Method: Study design using a cross sectional model. Data were obtained from 90 current university students and doctors.Result: The highest questionnaire overall scores were obtained was 83 and the lowest scores were 43. The understanding of PPE among medical students, Co-Ass, resident significantly differ in the understanding of PPE (p<0.001). Resident is significantly different (p<0.001) than the other two groups, but there is no significant difference between the Co-Ass and Medical students.Conclusion: This study provides an overall understanding of universal precautions among medical students, Co-Ass and resident in Universitas Udayana. Findings will serve as a basis for future researchers to conduct future intervention studies.
Hubungan antara Platelet Lymphocyte Ratio (PLR) dan respon Neoadjuvant Chemotherapy (NAC) CAF pada pasien Locally Advanced Breast Cancer Aryo Wibisono; I Nengah Wiadnyana Steven Christian; Putu Anda Tusta Adiputra
Intisari Sains Medis Vol. 11 No. 2 (2020): (Available online: 1 August 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.635 KB) | DOI: 10.15562/ism.v11i2.754

Abstract

Background: The incidence of LABC (Locally Advanced Breast Cancer) in Indonesia is estimated more than 50%, and in Bali as many as 76.3% from all of breast cancer cases. Response of NAC (Neoadjuvant chemotherapy) in LABC case is not the same on each patient. Currently, there are several biomarkers that can be a predictor of NAC response on LABC. One of them is PLR (platelet lymphocyte ratio). PLR is an easy, cheap and fast marker to be counted, but not all clinicians know its role. Lack of research in the relationship of PLR to NAC CAF (Cyclophospamide, Adriamycin, 5 Flourouracil) response in patients with LABC are currently making researchers interested in studying it.Method: This research is observational analytics, using a retrospective cohort study.  The number of samples was 62 (consecutive sampling), obtained from the medical records of patients who had undergone NAC CAF from 2015-2019 at Sanglah Hospital Denpasar.  PLR value  and initial tumor size were calculated before undergoing chemotherapy, then assessed the NAC CAF response to tumors after undergoing 3 cycles of chemotherapy. Positive response if tumor size is reduced and  negative response if the tumor size is persists or enlarges. In this study use a cut off point of PLR 150.Results: From 62 respondents obtained PLR value ≤ 150 had a positive response of 77.1% and 22.9% had a negative response. From these results obtained a correlation between PLR value with responses to NAC CAF in LABC patients, where low PLR values had  positive responses 1.6 times (IK 95; 1.04 - 2.47) with an output value of p = 0.018.Conclusion: There is a correlation between PLR and NAC CAF response, where a low PLR value (PLR ≤ 150) has a positive response to NAC CAF in LABC patients. Latar Belakang: Angka kejadian LABC (Locally Advanced Breast Cancer) di Indonesia diperkirakan lebih dari 50%, dan di Bali sebanyak 76,3% dari semua kasus kanker payudara. Respon NAC (neoadjuvant chemotherapy) pada kasus LABC tidak sama pada setiap penderita. Saat ini terdapat beberapa biomarker yang dapat menjadi prediktor terhadap respon NAC pada LABC, salah satunya adalah PLR (platelet lymphocyte ratio). PLR merupakan suatu marker yang mudah, murah dan cepat untuk dinilai tetapi masih banyak klinisi yang belum mengetahui perannya. Kurangnya penelitian mengenai hubungan PLR terhadap respon NAC CAF (Cyclophospamide, Adriamycin, 5 Flourouracil) pada pasien LABC saat ini membuat peneliti tertarik untuk meneliti hal tersebut.Metode: Jenis penelitian analitik observasional menggunakan studi kohort retrospektif, dengan 62 responden (consecutive sampling), yang didapatkan dari rekam medis pasien yang telah menjalani NAC CAF dari tahun 2015-2019 di RSUP Sanglah Denpasar. Nilai  PLR  dan ukuran tumor awal dihitung sebelum kemoterapi, kemudian dinilai respon NAC CAF terhadap tumor setelah menjalani 3 siklus kemoterapi. Respon positif  yaitu jika terjadi reduksi ukuran tumor ≥ 30% dari ukuran tumor awal dan respon negatif  jika terjadi reduksi ukuran tumor < 30%. Penelitian ini menggunakan cut off point  PLR 150,0 yang didapatkan dari penelitian sebelumnya.Hasil: Dari 62 responden didapatkan nilai PLR ≤ 150 mempunyai respon positif sebanyak 77,1% dan 22,9% respon negatif. Dari hasil tersebut didapatkan hubungan antara nilai PLR dengan respon terhadap NAC CAF pada pasien LABC, dimana nilai PLR rendah mempunyai respon positif sebanyak 1.6 kali (IK 95; 1.04 – 2.47) dengan hasil output nilai p = 0.018.Kesimpulan: Terdapat hubungan antara PLR terhadap respon NAC CAF, dimana nilai PLR yang rendah (≤ 150) mempunyai respon positif terhadap NAC CAF pada pasien LABC.  
Hubungan antara Microvessel Density dan Lymphovascular Invasion dengan metastasis jauh pada pasien kanker payudara di RSUP Sanglah, Bali, Indonesia Trisye Septiawati; Ida Bagus Tjakra Wibawa Manuaba; Putu Anda Tusta Adiputra
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (361.717 KB) | DOI: 10.15562/ism.v11i3.823

Abstract

Background: Breast cancer is the most common malignant tumor in Indonesia, with a relative frequency of 18,6%. Mortality in breast cancer most are caused by distant metastasis, which then causes multiple organ failure. To start a metastatic process requires new blood vessels (angiogenesis) and infiltration of the lymphatic system. Both can be assessed through microvessel density and lymphovascular invasion. This study aims to determine the relationship between Microvessel Density and Lymphovascular Invasion with metastasis in breast cancer patients at Sanglah General Hospital, Bali, Indonesia.Methods: A cross-sectional analytic study was conducted at the oncology surgical clinic from January 2018 - March 2019. Of the 62 biopsy samples were stained using hematoxylin-eosin and were observed by one pathologist. MVD cut-off points are taken by calculating the mean and standard deviation. Bivariate analysis using Chi-Square Test and multivariate analysis using logistic regression test was used for statistical analysis. Data were analyzed using SPSS version 23 for Windows.Results: From the results of a bivariate analysis, it was found that the high MVD is correlated with distant metastasis (P = 0.001) and positive LVI with metastasis (P = 0.003). There is a relationship between high MVD and tumor size (P = 0,000).Conclusion: Multivariate analysis confirmed that high MVD and positive LVI were statistically related to the occurrence of metastasis in breast cancer patients. Latar Belakang: Kanker payudara merupakan salah satu jenis kanker terbanyak di Indonesia dengan frekuensi relatif sebesar 18,6%. Kematian pada kanker payudara sebagian besar disebabkan oleh metastasis jauh yang kemudian menyebabkan kegagalan organ multipel. Untuk memulai suatu proses metastasis diperlukan pembentukan pembuluh darah baru (angiogenesis) dan juga infiltrasi sistem limfatik. Kedua hal tersebut bisa dinilai melalui microvessel density dan lymphovascular invasion. Penelitian ini bertujuan untuk mengetahui hubungan antara Microvessel Density dan Lymphovascular Invasion dengan metastasis jauh pada pasien kanker payudara di RSUP Sanglah, Bali, Indonesia.Metode: Penelitian potong lintang analitik dilakukan pada poliklinik bedah onkologi selama Januari 2018–Maret 2019. Dari 62 sampel biopsi dilakukan pembacaan microvessel dan lymphovascular invasion yang telah lebih dulu diberikan pewarnaan hematoxylin eosin oleh 1 patologi anatomi. Cut off point MVD diambil dengan cara menghitung mean dan standar deviasi. Analisis bivariat dengan Uji Chi-Square dan analisis multivariat dengan menggunakan uji regresi logistik digunakan untuk analisis statistik. Data dianalisis dengan SPSS versi 23 untuk Windows.Hasil:  Dari hasil analisis bivariat didapatkan hubungan antara MVD yg tinggi dengan metastasis (P = 0,001) dan hubungan antara LVI positif dengan metastasis (P = 0,003). Terdapat hubungan antara MVD dengan ukuran tumor (P = 0,000).Simpulan: Analisis multivariat menegaskan bahwa MVD yang tinggi dan LVI positif berhubungan secara statistik dengan terjadinya metastasis pada pasien kanker payudara. 
Relationship between Monocarboxylate Transporter 4 (MCT-4) Expression and Breast Cancer Clinicopathology and Subtype in Sanglah General Hospital, Denpasar, Indonesia Gede Andry Nicolas Andry Nicolas; I Wayan Sudarsa; Putu Anda Tusta Adiputra; Desak Made Wihandani; I Gede Putu Supadmanaba
Intisari Sains Medis Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.108 KB) | DOI: 10.15562/ism.v13i1.1274

Abstract

Background: Breast cancer is the second leading cause of death in women in developing countries. The activity of Warburg and Reverse-Warburg effects on breast cancer is reflected by the expression patterns of two molecules, namely caveolin-1 and Monocarboxylate Transporter-4 (MCT-4). MCT-4 is a transmembrane transport protein that transports lactate from the cytoplasm to the intercellular fluid.Method: This is a cross-sectional analytical study to determine the relationship between MCT-4 expression and breast cancer clinicopathology and subtypes. The study was conducted between April and May of 2020 with 62  breast cancer patients as samples in Sanglah General Hospital, Denpasar. Analysis was done with SPSS 25.Results: A logistic regression analysis was performed to analyze the relationship between the dependent variable (MCT-4) and the covariates (stage, grade, and subtype). Of the three variables significantly associated with MCT-4 expression, only clinical-stage and subtype (luminal and non-luminal) remained independently associated with MCT-4 expression. Analysis on the clinical stage and subtype variables showed an adjusted OR of 4.727 (p = 0.047; 95% CI: 1.109 - 21.922) and 17.850 (p = 0.009; 95% CI: 2.069 - 154.003) , respectively. This suggests that MCT-4 has a significant association with subtype and clinical-stage, increasing the risk of cancer stage progression and developing a more malignant (non-luminal) subtype.Conclusion: High MCT-4 expression was significantly associated with malignant subtypes, high histological-grade cancer and advanced breast cancer.
Faktor Yang Mempengaruhi Rekurensi Pada Pasien Kanker Payudara Pasca Modified Radical Mastectomy di RSUP Prof. Dr. I G.N.G Ngoerah Made Revina Chandradewi; Ida Bagus Tjakra Wibawa Manuaba; Putu Anda Tusta Adiputra
Intisari Sains Medis Vol. 13 No. 3 (2022): (In Press 1 December 2022)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/ism.v13i3.1544

Abstract

Background: In Indonesia, the incidence of breast cancer is 42,1 per 100,000 people, whereas the average mortality rate is 17 per 100,000 people. 8-10% of women with breast cancer will experience locoregional recurrence, and 15-30% may develop distant metastases. This study aimed to examine if cancer subtypes, histological grading, and LVI were linked with breast cancer recurrence in patients after Modified Radical Mastectomy at Prof. RSUP. Dr. I G.N.G. Ngoerah. Methods: Medical record data are used as the study data source to discover the factors that impact breast cancer recurrence in patients who have had a modified radical mastectomy. This research was done using a sequential sampling method. This study's sample utilized inclusion and exclusion criteria to generate 363 patients. The data obtained were analyzed using SPSS ver 22. Results: The results revealed that 327 patients, or 90.1%, did not have a recurrence, whereas 36 patients, or 9.9%, did. There were 50 Luminal A subtype patients, 127 Luminal B subtype patients, 61 Luminal-Her2 subtype patients, 65 Her2 subtype patients, and 60 TNBC subtype patients. 231 individuals were found to have a negative LVI, whereas 132 patients had a positive LVI. Forty-seven individuals were diagnosed with grade I, 174 with grade II, and 142 with grade III. Breast cancer recurrence was significantly impacted by LVI (p<0.05). Conclusion: LVI is strongly related to breast cancer recurrence in patients undergoing Modified Radical Mastectomy, but subtype and histological grading are not.   Latar Belakang: Angka kejadian kanker untuk kanker payudara di Indonesia sebesar 42,1 per 100.000 penduduk dengan rata-rata kematian sebesar 17 per 100.000 penduduk. Antara 8-10% wanita yang didiagnosis dengan kanker payudara akan mengalami kekambuhan locoregional dan 15-30% akan mengalami metastasis jauh. Tujuan penelitian ini dilakukan yaitu untuk mengetahui apakah subtipe kanker, grading histopatologi dan LVI menjadi faktor yang berhubungan dengan terjadinya rekurensi kanker payudara pada pasien pasca Modified Radical Mastectomy di RSUP Prof. Dr. I G.N.G Ngoerah. Metode: Desain penelitian cross sectional digunakan dalam penelitian ini, dimana data rekam medis menjadi sumber data penelitian. Penelitian menggunakan pengambilan sampel secara konsekutif. Sampel dalam penelitian menggunakan kriteria inklusi dan eksklusi dan diperoleh jumlah sampel 363 pasien. Data yang didapatkan dianalisis dengan menggunakan SPSS ver 22. Hasil: Hasil penelitian menunjukkan sebanyak 327 pasien atau sebesar 90,1% tidak rekuren, sedangkan 36 pasien atau sebesar 9,9% mengalami rekurensi. Terdapat 50 pasien dengan subtipe Luminal A, 127 pasien dengan subtipe Luminal B, 61 pasien dengan subtipe Luminal-Her2, 65 pasien dengan subtipe Her2, dan 60 pasien dengan subtipe TNBC. Dari 231 pasien didapatkan dalam kategori LVI negatif, sedangkan 132 pasien memiliki LVI positif. Sebanyak 47 pasien didapatkan dengan grade I, 174 pasien dengan dengan grade II, dan 142 pasien memiliki grade III. LVI memiliki pengaruh signifikan (p<0,05) terhadap rekurensi kanker payudara. Simpulan: LVI berhubungan signifikan terhadap rekurensi kanker payudara pada pasien pasca Modified Radical Mastectomy, sedangkan subtipe dan grading histopatologis tidak.
Analisis Biaya dan Manfaat Pemeriksaan CA 15-3 dalam Diagnostik dan Pemantauan Kanker Payudara di Era BPJS I Gede Budhi Setiawan; Putu Anda Tusta Adiputra
JBN (Jurnal Bedah Nasional) Vol 7 No 1 (2023): JBN (Jurnal Bedah Nasional)
Publisher : Program Studi Ilmu Bedah, Fakultas Kedokteran Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JBN.2023.v07.i01.p04

Abstract

Tujuan: Untuk menganalisa penggunaan sistem pembiayaan berdasarkan tarif INA-CBGs dalam penentuan rencana diagnosis, terapi dan monitoring agar pasien mendapat pelayanan terbaik dengan biaya seminimal mungkin. Salah satu yang perlu dipertimbangkan adalah peran pemeriksaan penanda tumor CA 15-3. Metode: Dilakukan telaah artikel untuk mengetahui peran dan manfaat penanda tumor CA 15-3, dibandingkan dengan biaya yang diperlukan untuk pemeriksaan pasien berdasarkan penelitian terbaru saat ini, guideine, pedoman nasional pelayanan kedokteran dan aturan tarif INA-CBGs. Hasil: Studi mengenai CA 15-3 memiliki hasil yang bervariasi sebagai pemeriksaan untuk menunjang diagnosis, penentuan staging, monitoring respon terapi, dan prognosis pasien. Berdasarkan guideline saat ini, CA 15-3 bukan merupakan penanda tumor yang utama pada kanker payudara dan hasil pemeriksaan CA 15-3 saja tidak dapat digunakan sebagai pedoman diagnosis, monitoring terapi, dan penentu pilihan terapi pada pasien. Biaya pemeriksaan CA 15-3 sebesar 285.000 rupiah cukup terjangkau untuk dilakukan, namun tetap merugikan bila hasil pemeriksaan tidak mempengaruhi diagnosis, monitoring, prognosis, dan pilihan terapi pasien. Simpulan: Bukti yang ada saat ini menunjukkan bahwa tidak diperlukan pemeriksaan CA 15-3 pada kanker payudara mengingat diagnosis, monitoring, prognosis dan terapi tidak dipengaruhi oleh hasil CA 15-3 yang diperoleh.
Karakteristik dan Faktor Risiko Kanker Payudara di Rumah Sakit Umum Pusat Prof. Dr. I G.N.G Ngoerah Tahun 2022 Aqilah, Nadya Zalfa; Wetan, Ni Gusti Ayu Agung Manik Yuniawaty; Setiawan, I Gede Budhi; Adiputra, Putu Anda Tusta
E-Jurnal Medika Udayana Vol 13 No 07 (2024): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2024.V13.i07.P06

Abstract

Breast cancer is a disease that has high mortality in women throughout the world. Breast cancer has characteristics and risk factors that influence the incidence of breast cancer. The research method uses a retrospective descriptive study and uses secondary data, namely medical records at the Central General Hospital Prof. Dr. I G.N.G. Ngoerah in 2022. Of the total 551 samples, only 319 samples had complete medical records. The variables studied were age, clinical stage, histopathological type, biopsy grade, subtype, lesion location, menopausal status, age at menarche, age at menopause, family history of cancer, parity, breastfeeding history, history of hormonal therapy, and nutritional status in terms of BMI. The results showed that of the 319 breast cancer patients, 77.4% were ?45 years old, 38.2% were stage IIIB, 86.2% were invasive ductal carcinoma, 56.4% were grade III, 36.4% were luminal B subtype, 41.4% were in the menopausal phase, the average age of menarche was 13 years old, 42% had menopause in the 45-50 year age range, 4.4% had a family history of cancer, 73% were multiparous, 91.5% had a history of breastfeeding, 23.8% had a history of hormonal therapy, and 37.3% had a normal BMI nutritional status. Keywords: Characteristics, Risk Factors, Breast Cancer
GAMBARAN PASIEN KARSINOMA TIROID BERDIFERENSIASI DI RSUP SANGLAH TAHUN 2015-2020 Wisescistiati, Made Visvayoni; Yuniawaty Wetan, Ni Gusti Ayu Agung Manik; Manuaba, Ida Bagus Tjakra Wibawa; Adiputra, Putu Anda Tusta
E-Jurnal Medika Udayana Vol 11 No 4 (2022): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2022.V11.i04.P13

Abstract

ABSTRACT Background: differentiated thyroid carcinoma (DTC) is the most common type found in thyroid malignancies. Onset of the disease is influenced by several factors such as history of radiation exposure, environmental influences and iodine intake in certain areas. Due to the limited data in Indonesia related to the mapping of differentiated thyroid cancer cases, the author is interested in conducting this study. Objective: to determine the description of differentiated thyroid carcinoma patients in Sanglah General Hospital year 2015-2020. Methods: cross-sectional descriptive study. The population and samples were all patients diagnosed with differentiated thyroid cancer treated at the SMF/Surgery Department of Sanglah General Hospital year 2015 -2020. The variables in this study are age, gender, area of residence, main diagnosis, staging and therapy. Results: total sample obtained 223 patients. Most common age group were 41-50 years old with 52 people (23.3%). Women are more common with 173 people (77.6%). Denpasar City has the highest number of cases with 75 people (33.6%). The main diagnosis is papillary thyroid cancer (PTC) with 215 cases (96.4%). Stage I are most found with 140 cases (62.8%). Most widely given therapy is total thyroidectomy in 183 people (82.1%) and 124 people (55.6%) received radio ablation. Conclusion: In this study, differentiated thyroid carcinoma was mostly found in women, at the age of 41-50 years, residents living in Denpasar. Papillary thyroid cancer (PTC) as the most common type in stage I and mostly treated with total thyroidectomy. Keywords : description, differentiated thyroid carcinoma, sociodemographic
Co-Authors Agung Bagus S. Satyarsa and I. B. T. Wibawa-Manuaba Annisa Alviariza Aqilah, Nadya Zalfa Aryo Wibisono Ayu Nursantisuryani Jahya Ayu Sri Mahendra Dewi , I Gusti Chandrakirana, Anak Agung Ayu Hellin Desak Made Wihandani Dewa Putu Satria Juristiasa Dewi Prima Christian, Dewi Prima Gede Andry Nicolas Andry Nicolas Gusti Ngurah Agung Adi Paramartha Hendra P. Setiawan Hendra Sanjaya, I Gusti Putu Herman Saputra I Dewa Made Sukrama I G A Mirah K I G. P. Supadmanaba I Gde Made Satya Wangsa Satya Wangsa I Gusti Ayu M Prita Dewi I Gusti Ngurah Gde Dwi Aryanata I Ketut Wiargitha I Made Arya Winangun I Made Bagus Adhi Paramitha I Nengah Wiadnyana Steven Christian I W. Sudarsa I Wayan Niryana I. B. Tjakra Wibawa Manuaba Ida Bagus Yorky Brahmantya Inge Kurniawati Jasmine Stephanie Christian Jasmine Stephanie Christian K. Aditya Prayudi, Pande Kadek Santi Diahswari Widyadari Ketut Siki Kawiyana Made Agus Dwianthara Sueta Made Revina Chandradewi Manuaba, Ida Bagus Tjakra Wibawa Ni Gusti Ayu Agung Manik Yuniawaty Wetan Ni Ketut Hanny Puspita Ni Putu Ayu Pande Arista Dewi Ni Wayan Ariani Vitriasari Nirmala, Made Sinta Ayu Suci P. Setiawan, Hendra Pande K. Aditya Prayudi Permatasari, Yulan Putu Diahpradnya Oka Partini Putu Gupta Arya Gumilang Putu Hendra Sanjaya, I Gusti Reni Widyastuti Ronald Natawidjaja Roy R.H. Hamid, Agus Roy Rusly Hariantana Hamid, Agus Setiawan, I Gede Budhi Sri Mahendra Dewi, I Gusti Ayu Sri Maliawan Tham Hong Yuan Thomas Arie Satya Wardhana Trisye Septiawati W Steven Chr, W Steven Wetan, Ni Gusti Ayu Agung Manik Yuniawaty Widia Putri, Gracia Wisescistiati, Made Visvayoni Yulan Permatasari Yuniawaty Wetan, Ni Gusti Ayu Agung Manik Yusuf Alfi Mulia