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All Journal International Journal of Public Health Science (IJPHS) Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Medical Journal of Indonesia MNJ (Malang Neurology Journal) Magna Neurologica Neurona
Prabaningtyas, Hanindia Riani
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : Magna Neurologica

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Neurological Complications After Covid 19 Vaccinations: Serial Case Report Sari, Intan Permata; Prabaningtyas, Hanindia Riani
Magna Neurologica Vol. 1 No. 1 (2023): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v1i1.430

Abstract

Background: COVID-19 vaccination has been carried out worldwide, with more than 5 million dose of vaccine delivered. Although declared safe, there are cases of neurological disorders after the Covid 19 vaccination. Cases: In the first case, a 20-year-old male came with decrease level of consciousness, 4 days after receiving the first dose of COVID 19 vaccine with Sinovac vaccine. MRI Brain shows acute disseminated encephalomyelitis (ADEM). In the second case, a 50-year-old male with seizures and decreased consciousness after recieving first dose of COVID-19 vaccination with Sinovac vaccine, 10 days before admission. Non contrast CT Scan and brain contrast MRI Brain revealed cerebral edema. In the third case, an 18-year-old woman had seizures and decreased consciousness one month after the first dose of COVID 19 vaccination with Sinovac. Contrast Head MRI showing focal leptomeningitis. In the fourth case, a 30-year-old male with slurred speech and right-sided weakness. Three months before admission, he had fever, headache, and tingling of the right limbs a few days after the first dose of COVID 19 vaccination with Sinova MRI Brain Contrast shows ADEM lesion Discussion: The mechanism of neurological disorders concerning COVID 19 vaccination is still unclear. Neurological complications after vaccination weaken the effort of vaccination, but can be used as a precaution and assess prognosis while waiting for further confirmation from large epidemiological studies and meta-analyses. Until now, it is believed that the COVID-19 vaccine has important benefits and is a hope for ending the COVID-19 pandemic.
Morse Fall Scale As Clinical Predictor Of 3-Month Neurologic Function Recovery On Ischemic Stroke Patients: A Prospective Cohort Study Sakti, Triono Agung; Hamidi, Baarid Luqman; Prabaningtyas, Hanindia Riani
Magna Neurologica Vol. 1 No. 1 (2023): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v1i1.431

Abstract

Background: Stroke is a leading cause of death in developing countries. The Morse Fall Scale (MFS)'s use in predicting stroke clinical outcomes has not been extensively studied. This study aims to assess MFS's ability to predict neurological recovery in acute ischemic stroke patients within 3 months using the National Institutes of Health Stroke Scale (NIHSS). Methods: This prospective cohort study enrolled all individuals with acute ischemic stroke between September and November 2021. Patients' baseline data included their MFS and NIHSS scores, as well as their age, gender, weight, stroke location, and comorbidities. The NIHSS score was reassessed three months later. To identify NIHSS predictors, all baseline data will be analyzed. SPSS 22 was used to analyze the data. The local ethics committee approved the study. Results: Of the 164 patients who met the criteria, only 105 (mean age 59.09 [±11.65], male [58.1%], anterior location [88.6%]) reached the study end point. The average NIHSS score decreased from 9.14 (±1.70) to 6.27 (±1.92). Multiple linear regression showed only the MFS score (p = 0.000) accurately predicted the NIHSS by 0.059 (95% CI: 0.032–0.085, p = 0.000) at the study's conclusion. Discussion: Our investigation revealed that the baseline MFS score accurately predicted neurological improvement in patients who had suffered an ischemic stroke over a three-month period. It is considered that the greater risk of falling results in a delay in the patient's rehabilitation. Investigation with larger sample sizes and longer monitoring intervals are required to corroborate our findings.
Recurrent Brain Abscess in 40-Years-Old Female Associated with Ventricular Septal Defect: A Case Report Fairuzya, Azmi Farah; Savitri, Martha Oktavia Dewi; Prabaningtyas, Hanindia Riani; Watanabe, Yasuhiro; Murakami, Takenobu; Tajiri, Yuki
Magna Neurologica Vol. 3 No. 1 (2025): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v3i1.1123

Abstract

Background: Ventricular septal defect (VSD) is one of the critical risk factors for brain abscess. The unsterile blood in uncontrolled cyanotic congenital heart disease cases will travel to the brain after escaping the filtration mechanism and cause brain abscess. Case: A 40-year-old female presented with a two-week course of moderate headaches, worsening severely four days before admission. Neurological manifestations included attention deficits, dysarthria, right-sided hemiparesis, and proper facial palsy. Laboratory findings indicated leukocytosis and polycythemia. Echocardiography revealed VSD. Brain MRI with contrast suggested a single abscess lesion in the left occipital lobe. A histopathological examination confirmed the diagnosis. Antibiotics were administered during hospitalization, with outpatient treatment afterward. A one-month follow-up revealed new symptoms and a subsequent surgical excision. Discussion: Brain abscess remains a challenging and life-threatening case despite advanced diagnostic techniques. Uncontrolled cyanotic heart disease might be an essential risk factor for brain abscess occurrence. Thorough diagnostic examinations must be conducted to establish the diagnosis. The optimal empirical-targeted antibiotic treatment is a cornerstone of management. After antibiotic therapy, a surgical approach must be considered in lesions with large-size or nonoptimal size reduction. It is essential to comprehensively manage brain abscesses and their etiology to reduce the recurrence rate. Conclusion: Brain abscess associated with uncontrolled cyanotic congenital heart disease requires comprehensive treatment involving antibiotics and surgery. Addressing underlying causes and cost-effective follow-ups with clinical and monthly imaging assessments are essential.
Co-Authors Bambang Purwanto Budianto, Pepi Diah Kurnia Mirawati Dono Indarto Fairuzya, Azmi Farah Hafizhan, Muhammad Hambarsari, Yetty Hamidi, Baarid Luqman Han Yang Hapsari, Maria Yosita Ayu Hutabarat, Ervina Arta Jayanti Ilhamsyah, Rudi intan permata sari Martha Oktavia Dewi Savitri Muhammad, Faizal Murakami, Takenobu Novian Anindito Santosa Ristinawati, Ira Rivan Danuaji Soetrisno Stefanus Erdana Putra Subandi Subandi SUROTO Suroto Suroto Tajiri, Yuki Tedjo, Raden Andi Ario Tejomukti, Teddy Triono Agung Sakti Vitri Widyaningsih Watanabe, Yasuhiro