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All Journal INDONESIAN JOURNAL OF LEGAL AND FORENSIC SCIENCES e-GIGI Dentika Dental Journal Medical Journal of Indonesia Dental Journal (Majalah Kedokteran Gigi) Padjadjaran Journal of Dentistry Journal of Indonesian Dental Association Majalah Anestesia dan Critical Care JOURNAL LA MEDIHEALTICO Journal La Lifesci Indonesian Health Journal Eduvest - Journal of Universal Studies
Elza Ibrahim Auerkari
Department Of Oral Biology, Faculty Of Dentistry, Universitas Indonesia
Aerospace Engineering Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Journal : Dental Journal (Majalah Kedokteran Gigi)

 1 
Serum C-reactive protein and C-reactive gene (-717C>T) polymorphism are not associated with periodontitis in Indonesian male patients Antonius Winoto Suhartono; Benso Sulijaya; Niniarty Zeiroeddin Djamal; Sri Lelyati Chaidar Masulili; Christopher Talbot; Elza Ibrahim Auerkari
Dental Journal (Majalah Kedokteran Gigi) Vol. 48 No. 3 (2015): September 2015
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (483.612 KB) | DOI: 10.20473/j.djmkg.v48.i3.p113-118

Abstract

Background: Periodontitis is an inflammatory disease caused by periodontal pathogens and influenced by multiple risk factors such as genetics, smoking habit, age and systemic diseases. The inflammatory cascade is characterized by the release of C-reactive protein (CRP). Periodontitis has been reported to have plausible links to increased level of CRP, which in turn has been associated to elevated risk of  cardiovascular disease (CVD). Purpose: The purpose of this study was t o investigate the relationship amongst the severity of periodontitis, CRP level in blood and CRP (-717 C>T) gene polymorphism in male Indonesian smokers and non-smokers. Method: The severity of periodontitis was assessed for 97 consenting male Indonesian smokers and non-smokers. The CRP level of the subjects was determined by using immuno-turbidimetric assay performed in PARAHITA Diagnostic Center Laboratory ISO 9001: 2000 Cert No. 15225/2. The rate of CRP (-717C>T) gene polymorphism was determined by using PCR-RFLP in Oral Biology Laboratory, Faculty of Dentistry, Universitas Indonesia. Result: The results suggest that the CRP protein level is not significantly associated with the tested CRP gene polymorphism (p>0.05). Also, while the severity of periodontitis increased significantly with subject age, the CRP level in blood serum was not significantly related to the severity of  periodontitis. The genotypes of the tested polymorphism did not show significant association with the severity of periodontitis either in smokers or in the combined population including smokers and non-smokers. The results naturally do not exclude such associations, but suggest that to discern the differences the sample size must be considerably increased. Conclusion: The CRP (-717C>T) gene polymorphism and CRP level in blood serum were not found to be associated with the severity of periodontitis in male smokers or in the combined population of smokers and non-smokers.
Runx2 rs59983488 polymorphism in class II malocclusion in the Indonesian subpopulation Fadli Jazaldi; Benny M. Soegiharto; Astrid Dinda Hutabarat; Noertami Soedarsono; Elza Ibrahim Auerkari
Dental Journal (Majalah Kedokteran Gigi) Vol. 54 No. 4 (2021): December 2021
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v54.i4.p216-220

Abstract

Background: Class II malocclusion is one of the main orthodontic issues for patients in seeking treatment. The prevalence of class II malocclusion varies in different populations. Variation in skeletal profile is mainly controlled internally by a regulatory gene. Runt-related transcription factor-2 (Runx2) plays a role in osteoblast differentiation and is highly expressed during development. Purpose: This study aimed to evaluate the relation of regulatory gene variation in the Runx2 promoter with class II malocclusion. Methods: DNA samples were acquired from 95 orthodontic patients in Jakarta, Indonesia, who were divided into two groups: class I skeletal malocclusion (control group) and class II malocclusion. A single nucleotide polymorphism was investigated using the polymerase chain reaction and restriction fragment length polymorphism techniques. The distribution of alleles was assessed using the Hardy-Weinberg test. The relationship between polymorphism and skeletal variation was assessed with the Chi-Square test and logistic regression. Results: The frequency distributions of genotypes and alleles were tested for Hardy-Weinberg equilibrium and found to be slightly deviated. There was an equal distribution of G and T alleles throughout class II and class I skeletal malocclusions and the Chi-Square test showed that this relationship was not significant (p=0.5). Conclusion: Runx2 rs59983488 polymorphism was found in the Indonesian subpopulation; however, an association between Runx2 rs59983488 polymorphism and class II skeletal malocclusion was not found.
Palatine suture obliteration method for age estimates of burn victims with minimal tooth remains: a case report Prastyo, Eko; Sari, Fitri Ambar; Auerkari, Elza Ibrahim; Suhartono, A. Winoto; Pasaribu, Roben Suhadi; Soedarsono, Nurtami; Zevrianty, Dieci; Yunus, Aditia Dedek; Auerkari, Pertti
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 3 (2025): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i3.p295-300

Abstract

Background: A disaster is a serious disruption in the functioning of a society that can cause many losses. It can be caused by nature or humans. When the loss of life is on a large scale, the recovery process is made more complicated by simultaneous identification operations. Biological profiling is of paramount importance when investigating cases; the age at which a victim dies is crucial for reconstructing the victim’s life. Purpose: The purpose of this case study is to highlight the utility of palatal suture obliteration as a valuable indicator for age estimation in adults, especially when there are minimal remaining dental elements that make age estimation by other methods of dental analysis impossible. Case: The author presents a case of burn victims due to a fire disaster in the fuel oil terminal area in Jakarta that killed several victims. As they were found in a visually unrecognizable condition, without identity documents, and in a state where the victims’ teeth left few dental elements, effort is needed to assist in identifying the victims, including victim age estimation techniques with ideal methods that can be applied in the field. Case management: The Crow-Glassman Scale (CGS) is used to describe the extent of burns to tissue remnants. On external examination, all body parts showed the burns reaching level 3 CGS. The victim is estimated to be over 50 years old. Decision making is based on the guidelines of the Mann method, wherein if more than 50% of the anterior median palatine suture is obliterated, then the minimum estimated age is 50 years. Conclusion: The obliteration of the palatal sutures can be used as supporting evidence when considered alongside other more reliable age indicators that can narrow down the age of unidentified individuals.
The role of forensic odontology in the identification of a mutilation victim: A case report Yatma, Debby; Auerkari, Elza Ibrahim; Yuniastuti, Mindya; Soedarsono, Nurtami; Suhartono, Antonius Winoto; Kaurow, Farah P.; Pasaribu, Roben Suhadi; Auerkari, Pertti
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p409-414

Abstract

Background: Forensic odontology is an invaluable resource for human identification. An individual’s bones and teeth may be the only remnants of their identity in certain situations where soft tissue has been lost, carbonized, or destroyed for any other reason. The body’s hardest and best-protected structures are found in teeth, and these have individual characteristics and are resistant to factors such as temperature and chemistry. When antemortem dental records are not available for comparison, dental profiling is performed. Purpose: This case study highlights the importance of teeth in the identification process and their usefulness in estimating biological profile factors such as sex, age, and population affinity. Case: The case of an unidentified woman who was found in a house in a severely decomposed, skeletonized state is presented. The unidentified body was sent to the Forensic Medicine Installation of Bhayangkara Level I Hospital to determine the cause of death and for dental identification. Case management: The body was suspected to be a victim of mutilation. Shovel shapes observed on the lingual surface of the lateral upper incisor and tori palatini are the most outstanding diagnostic features in Mongoloid populations. The specific mesiodistal crown width and mandibular canine index revealed female traits. Using the Lamendin method, the age was estimated to be 52–58 years old. Conclusion: A forensic odontologist can identify individuals by comparing antemortem and postmortem dental data. They can also provide age estimation, sex, and population affinity determination by analyzing teeth.
Co-Authors Andi Izham Antonius Winoto Suhartono, Antonius Winoto Astrid Dinda Hutabarat Auerkari, Pertti Benny M. Soegiharto Benso Sulijaya, Benso Christopher Talbot Dewi Nurul Mustaqimah Dewi Nurul Mustaqimah Eko Prastyo Fadli Jazaldi Ferry P. Gultom, Ferry P. Firdaus, Riyadh Gultom, Ferry Pergamus Januarrifianto, Desy Kaurow, Farah P. Kaurow, Farah Primadani Ken Sekar Langit Khan, Muhammad S. Khan, Muhammad Salman Kiranahayu, Rarasih Latief, Benny Sjariefsjah Lies Zubardiah Lies Zubardiah Meilana, Andi N. S. T. Meilana, Andi Nur Sakina Tri Mindya Yuniastuti Mustaqimah Dewi Nurul Mustaqimah Dewi Nurul Niniarty Zeiroeddin Djamal Noertami Soedarsono Nurtami Soedarsono Oktaviana, Fahriza R. Oktavinda Safitry Pasaribu, Roben S. Pasaribu, Roben Suhadi Pattihahuan, Ira Zefanya Rijaldi, Ferdy Rusmaputeri, Fadhilah Salman Khan, Muhammad Sandi, Indah Maydila Sari, Fitri Ambar Satriyo, Juanda Sri Lelyati C Masulili Suhartono, A. Winoto Suhartono, Antonius W. Sulistyani, Lilies Dwi Tienneke Riana Septiwidyati Yatma, Debby Yudy, Yudy Yunus, Aditia Dedek Zevrianty, Dieci