Article Per Year (5 Year)
p-Index From 2020 - 2025
2.461
P-Index
This Author published in this journals
All Journal Transformasi: Jurnal Pengabdian Masyarakat WMJ (Warmadewa Medical Journal) Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) The Indonesian Biomedical Journal Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Majalah Patologi Indonesia Jurnal Sewaka Bhakti Aesculapius Medical Journal Indonesian Journal of Cancer INCOME: Indonesian Journal of Community Service and Engagement Jurnal Pandu Husada
Desak Putu Oki Lestari
Universitas Warmadewa
Religion Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 15 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 15 Documents
Search

 1   2 
The Correlation of PD-L1 Overexpression With Tumor Budding In Cervical Carcinoma Lestari, Desak Putu Oki; Analysa, Analysa; Armerinayanti, Ni Wayan; Riasa, I Nyoman Putu; Artha, I Gusti Alit
Indonesian Journal of Cancer Vol 18, No 3 (2024): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i3.1103

Abstract

Background: Several studies have proven the relationship between PD-L1, which is known as an immunotherapy target, and poor prognosis. The presence of a tumor budding (TB) group tumor outside the main tumor is also associated with a poor prognosis. The purpose of this study was to determine the relationship between PD-L1 and the grade of TB in cervical carcinoma. Methods: The design of this research is a case-control study with a retrospective approach. The sample is from a paraffin block of the primary cervical cancer tumor from the results of surgery in Balimed Denpasar Hospital between 2020 and 2023. From the statistical formula for the case-control study, a minimum sample of 15 is obtained for the case group with the criteria of high-grade TB, while 15 people were in the control group with low-grade TB. Immunohistochemistry (IHC) PD-L1 is positive if the membrane or cytoplasm is brown, and is negative if there is no brown color on the membrane or cytoplasm. Inferential statistics were used to evaluate the relationship between PD-L1 overexpression and low- and high-grade TB in cervical carcinoma using a chi-square test. Results: The results of this research revealed (p = 0.273) that there was no correlation between PD-L1 expression and high- and low-grade TB. Overexpression of PD-L1 was associated with a 2.250-fold increased risk of high-grade TB (OR = 2.250 with a 95% confidence interval of 0.103–1.915). Conclusions: The severity of TB does not correlate with PD-L1 expression. The functions of PD-L1 and other variables in the carcinogenesis of TB development are the cause of this weak association.
Empowering teachers and committees of Raudhatul Atfal Al Amin Tabanan for early cancer prevention through diverse, nutritious, balanced and food safety movement (B2SA) Analysa; Primadi, Putu; Lestari, Desak Putu Oki; Artha, I Gusti Alit; Riasa, I Nym Putu; Yusuf, M.
Transformasi: Jurnal Pengabdian Masyarakat Vol. 20 No. 2 (2024): Transformasi Desember
Publisher : LP2M Universitas Islam Negeri Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20414/transformasi.v20i2.9951

Abstract

[Bahasa]: Kanker merupakan salah satu penyebab utama kematian di seluruh dunia dengan jumlah kasus yang terus meningkat. Pemahaman tentang faktor risiko, gaya hidup sehat, dan pentingnya deteksi dini dapat memainkan peran yang signifikan dalam menurunkan angka kasus kanker. Pengabdian masyarakat ini bertujuan untuk memberdayakan guru dan komite di Raudhatul Athfal (RA) Al Amin, Tabanan, dalam upaya pencegahan kanker sejak dini. Peningkatan kesadaran dan praktik hidup sehat dilakukan melalui pelatihan dan sosialisasi Gerakan B2SA (Beragam, Bergizi, Seimbang, dan Aman) serta konsep Isi Piringku. Program ini dirancang untuk membekali para pendidik dengan pengetahuan dan keterampilan dalam mengajarkan pola makan sehat serta gaya hidup yang dapat mencegah faktor risiko kanker kepada anak-anak usia dini. Kegiatan pengabdian ini dilakukan dengan metoda penyuluhan aktif dan praktik yang melibatkan mitra yaitu guru, komite sekolah dan wali murid. Program dilakukan pada sekolah (RA) yang berada di tengah kota yang di banjiri oleh kuliner modern. Penyuluhan dan praktik dilakukan dengan cara menjadikan guru RA sebagai pendidik sekaligus motivator, dan komite merupakan ujung tombak gerakan ini. Hasil evaluasi menunjukkan adanya peningkatan pengetahuan mencapai 91,3%, sedangkan peningkatan sikap mencapai 89,2%. Disimpulkan bahwa terjadi peningkatan pengetahuan dan sikap pada semua responden tentang pencegahan kanker melalui gerakan B2SA. Kata Kunci: pencegahan kanker, B2SA, isi piringku, raudhatul atfal [English]: Cancer is one of the leading causes of death worldwide, with increasing numbers of cases. Early understanding of cancer causes, risk factors, healthy lifestyles, and early detection can play a vital role in reducing the number of cancer cases. This community service aims to empower teachers and the committee at Raudhatul Athfal (RA) Al Amin, Tabanan, to prevent cancer from an early age. Increased awareness and practice of healthy living are achieved through training and socialization of the B2SA Movement (Beragam, Bergizi, Seimbang, Aman) and the concept of "Isi Piringku". This program is designed to equip educators with the knowledge and skills to teach healthy eating patterns and lifestyles that can prevent cancer risk factors in young children. This community service activity was conducted using active counseling and practical methods involving partners such as teachers, school committees, and parents. The program was conducted at a kindergarten (RA) in the city center, which is flooded with modern culinary offerings. Counseling and practice are carried out by making RA teachers both educators and motivators, and the committee is the spearhead of this movement. The results show an increase in knowledge reaching 91.3%, while the increase in attitude reached 89.2%. It is concluded that there was an increase in knowledge and attitude among all respondents regarding cancer prevention through the B2SA movement. Keywords: cancer prevention, B2SA, plan my plate, preschool
Optimalisasi Potensi Ekowisata Melalui Edukasi Bahaya Mikroplastik dan Inovasi Wine Jeruk di Desa Pengejaran Lestari, Desak Putu Oki; Sudiarta, I Wayan; Sari, Ini Luh Putu Eka Kartika; Sukmadewi, Desak Ketut Tristiana
INCOME: Indonesian Journal of Community Service and Engagement Vol 4 No 1 (2025)
Publisher : EDUPEDIA Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56855/income.v4i1.1270

Abstract

The Assisted Village Empowerment Program activities in Pengjaran Village, Kintamani, aim to optimize ecotourism through socializing the impact aof microplastics and innovation in processing oranges into wine. This village has enormous potential in the production of Siamese oranges but faces the challenges of overproduction and a lack of value-added processed products. This program involves training for Family Planning Program mothers regarding the dangers of microplastics and techniques for making orange wine, using outreach and hands-on methods. The results showed an increase in participants' knowledge about the impact of microplastics and their ability to produce orange wine. By reducing plastic use and promoting sustainable use of local resources, we hope to improve economic welfare and health in society. This program also supports the tourism industry by offering processed products that are attractive to tourists, thereby making a positive contribution to the local economy.
Peningkatan Peran OSIS Dalam Pencegahan Kanker Serviks Dan Vaksinasi HPV Pada Siswi SMP di Bali Lestari, Desak Putu Oki; Analysa, Analysa; Kerans, Fransiscus Anthony; Winata, I Gde Sastra; Riasa, I Nyoman Putu
INCOME: Indonesian Journal of Community Service and Engagement Vol 4 No 3 (2025)
Publisher : EDUPEDIA Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56855/income.v4i3.1496

Abstract

Kanker serviks merupakan jenis kanker tertinggi ke-2 di Bali dan Indonesia, dengan infeksi virus HPV high risk sebagai faktor risiko utama. Meskipun vaksinasi HPV efektif menurunkan insiden kanker serviks, implementasinya di Indonesia, khususnya Bali masih baru dimulai dan tingkat pengetahuan remaja tentang kanker serviks masih rendah. Kegiatan pengabdian kepada masyarakat (PKM) ini bertujuan untuk meningkatkan pengetahuan, sikap, dan perilaku siswi SMP, khususnya pengurus OSIS terkait pencegahan kanker serviks dan vaksinasi HPV, serta mendorong peran aktif OSIS sebagai agen edukasi di lingkungan sekolah. Program dilakukan melalui penyuluhan aktif, pelatihan, dan pendampingan kepada pengurus OSIS di tiga SMP di Bali. Evaluasi dilakukan menggunakan pre-test dan post-test untuk mengukur perubahan pengetahuan, sikap, dan perilaku, serta pemantauan capaian vaksinasi HPV. Terdapat peningkatan signifikan pada nilai pengetahuan (dari rata-rata 3,47 menjadi 8,74), sikap (4,12 menjadi 9,32), dan perilaku (3,54 menjadi 9,01) setelah intervensi (p < 0,05). Cakupan vaksinasi HPV mencapai lebih dari 95%. Sebanyak 75% siswa mampu melakukan edukasi di kelompok kecil, dan 25% mampu melakukan penyuluhan di kelas besar. Intervensi berbasis OSIS efektif meningkatkan pengetahuan, sikap, perilaku, dan cakupan vaksinasi HPV pada siswa SMP. Peran OSIS sebagai duta kesehatan perlu terus didukung untuk memperluas dampak edukasi pencegahan kanker serviks di lingkungan sekolah.
Correlation of Age, Tumor Size, and Histopathological Type with Indicator Tumor Progression of Penile Squamous Cell Carcinoma in Bali Astuti, Ni Luh Putu Vina Juni; Lestari, Desak Putu Oki; Sari, Ni Luh Putu Eka Kartika; Armerinayanti, Ni Wayan; Evayanti, Luh Gde; Perdana, I Gede Sukma Okta
Indonesian Journal of Cancer Vol 19, No 3 (2025): September
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i3.1340

Abstract

Background: Penile cancer is a rare malignancy globally, but Bali accounts for approximately 40% of Indonesia’s cases. Age, tumor size, and histopathological type are recognized factors influencing penile cancer progression, with grade, depth of invasion, lymph node metastasis, and distant metastasis serving as key indicators. However, the prognostic value of these factors, particularly depth of invasion, remains debated. This study aimed to evaluate the correlation between age, tumor size, and histopathological type with indicators of tumor progression in penile squamous cell carcinoma (SCC) in Bali.Method: A cross-sectional analytical study was conducted on 160 cases of penile SCC. Dependent variables included tumor grade, depth of invasion, and lymph node metastasis, while independent variables were age, tumor size, and HPV status (inferred from histopathology). Age was categorized as 60 or ≥60 years, tumor size as 4 cm or ≥4 cm, and depth of invasion as T1–T4. Multivariate analysis using the chi-square test was performed to assess associations.Results:  Most patients were aged ≥ 60 years, had HPV-independent SCC, tumor size ≥ 4 cm, grade 2 tumors, and T1 depth of invasion, with lymph node metastasis observed in a minority. Multivariate analysis revealed significant correlations between age, tumor size, and histopathological type with grade (p = 0.026, R² = 0.056), depth of invasion (p 0.001, R² = 0.445), and lymph node metastasis (p = 0.004, R² = 0.075). Tumor size demonstrated the strongest association with depth of invasion (OR = 9.618, p 0.001) and lymph node metastasis (OR = 6.846, p 0.001).Conclusion: Tumor size is a significant predictor of both depth of invasion and lymph node metastasis in penile SCC. Clinical assessment of tumor size should be emphasized as a key prognostic factor to guide early intervention strategies in patients with penile SCC in Bali.
Co-Authors Alexandria Stephanie Suparman Analysa Analysa Analysa Analysa, Analysa Artha, I Gusti Alit Astuti, Ni Luh Putu Vina Juni Ayu Savitri Siskayani Cahyawati, Putu Nita Gede Khrisnanda Arya Dharma I Gde Sastra Winata I Gusti Alit Artha I Ketut Suwiyoga I Made Toya Ariawan I Nyoman Putu Riasa I Wayan Sudiarta I Wayan Suwarna Kartika Sari Kerans, Fransiscus Anthony Ketut Mulyadi Mulyadi Luh Gde Evayanti M. Yusuf Ni Luh Putu Eka Kartika Sari Ni Wayan Armerinayanti Ni Wayan Armerinayanti Ni Wayan Armerinayanti Ni Wayan Armerinayanti, Ni Wayan Novitasari Novitasari Perdana, I Gede Sukma Okta Primadi, Putu Riasa, I Nym Putu Riasa, I Nyoman Putu Sari, Ini Luh Putu Eka Kartika Sari, Ni Luh Putu Eka Kartika Septi Panca Sakti Sri Ratna Dewi Sukmadewi, Desak Ketut Tristiana Vivitri Dewi Prasasty Yudhi Nugraha