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All Journal VISIKES JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Wiyata : Penelitian Sains dan Kesehatan Cendekia Journal of Pharmacy Bioscientist : Jurnal Ilmiah Biologi JOURNAL OF COMMUNITY ENGAGEMENT AND EMPOWERMENT Journal of Pharmacy Science and Technology Jurnal Pharma Bhakta
Lia Agustina
Fakultas Farmasi, Institut Ilmu Kesehatan Bhakti Wiyata, Kediri
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Education Environmental Science Health Professions Immunology & microbiology Library & Information Science Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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OPTIMASI DAN UJI MUTU FISIK FORMULASI MASKER GEL PEEL – OFF KULIT PISANG (Musa paradisiaca L) Lia Agustina; Dewi Mega Ayu Pertiwi; Ninis Yuliati
JOURNAL OF PHARMACY SCIENCE AND TECHNOLOGY Volume 3 No. 1: Juli 2022
Publisher : Prodi Farmasi Fakultas Kedokteran Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/pst.v3i1.36

Abstract

Kepok banana (Musa paradisiaca L.) is one of the most commonly consumed bananas in Indonesia. Apart from the fruit, the other potentially used is banana peel. Kepok banana peel is rich in flavonoids which has function as antioxidants that protect skin from free radicals. In this study, we optimized and conducted physical characterization for banana peels peel-off gel mask. The aim for this research was to optimize the peel-off gel mask and analized the physical characteristics of peel-off mask gel. The formulation was optimized with different concentration of active substance. The physical characterization was organoleptic observation, homogeneity, pH, dispersibility, adhesion, drying time, irritation and stability assay. Organoleptics observation showed that peel-off gel showed distinctive scent, brownish color and gel-like structure. All preparation were homogenous, pH value dispersibility, adhesion, and drying time was within the required criteria. The peel-off was not irritant as showed from irritation assay. The preparation was also stable during 12 weeks storage under room temperature condition. We conclude that banana peels peel-off gel mask was successfully formulated. Further observation for its effectivity will be required.
Uji Daya Hambat Ekstrak Etanol dan N-Heksana Daun Labu Kuning (Cucurbita moschata D.) terhadap Bakteri Staphylococcus epidermidis Herlinda Mawardika; Lia Agustina; Ovie Resta Vanesha
Bioscientist : Jurnal Ilmiah Biologi Vol 11, No 1 (2023): June
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v11i1.7687

Abstract

Pumpkin leaf plant (Cucurbita moschata D.) is commonly used to treat gastric pain, jaundice, hipercholesterol, and contains antibacterial compounds. Nature products derived from plants are often used to treat facial skin disease by inhibiting acne-causing bacteria. Staphylococcus epidermidis has important role in acne formation. This research aims to determine the antibacterial activity, Minimum Inhibitory Concentration (MIC), and Minimum Bactericidal Concentration (MBC) of 70% ethanol extract and n-hexane against Staphylococcus epidermidis. Pumpkin leaf extracts were obtained by maceration technique then diluted to obtain the extracts with concentrations of 10%, 25%, and 50%. The antibacterial activity test of pumpkin leaves was carried out in vitro by well diffusion method on Mueller Hinton Agar (MHA) media, while MIC and MBC was determined by dilution method using different concentration of extract. The results of this research showed that there was inhibition zone formed at concentration 10%, 25%, and 50% of 70% ethanol extract of yellow pumpkin leaves. According to the result, the largest inhibition zone was obtained at concentration of 50% (20.02 ± 0,28 mm). The MIC value was found at concentration of 12.5% and MBC value was determined at 50% concentration of ethanol extract. Meanwhile, n-hexane extract of yellow pumpkin leaves has no antibacterial activity against S. epidermidis. It can be concluded that ethanol extract of yellow pumpkin leaves has potent antibiotic material for S. epidermidis.
FORMULASI DAN UJI MUTU FISIK SEDIAAN FACE SCRUB KULIT ARI KEDELAI (Glycine max) Lia Agustina; Vindy Sheila; Ninis Yuliati
JURNAL PHARMA BHAKTA Vol 2 No 1 (2022): Juni 2022
Publisher : FAKULTAS FARMASI, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

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Abstract

Latar belakang: Kerusakan kulit paling banyak disebabkan oleh radikal bebas salah satunya ditandai dengan kulit kering. Kedelai mengandung isoflavon sebagai antioksidan. Antioksidan dalam kosmetik memberikan efek kelembapan kulit. Kedelai dapat dimanfaatkan menjadi kosmetika yaitu scrub. Face scrub salah satu produk kosmetik pembersih yang menipiskan kulit wajah (exfoliating cleanser) digunakan karena mampu mengangkat sel kulit mati yang tidak dapat dibersikan kosmetik pembersih. Tujuan: Penelitian ini bertujuan Mengetahui pengaruh dari variasi konsentrasi kedelai terhadap kualitas fisik gel face scrub dan mengetahui pengaruh variasi konsentrasi kedelai terhadap efektivitas peningkatan kelembapan kulit yang berbeda. Metode: penelitian ini dibuat sediaan gel face scrub lalu dievaluasi karakteristik gel face scrub meliputi uji organoleptis, uji homogenitas, uji pH, uji daya sebar, uji daya lekat, dan iritasi. Selanjutnya diuji peningkatan efektivitas kelembapan menggunakan alat skin detector. Simpulan: Hasil penelitian ini menunjukan adanya pengaruh variasi konsentrasi kedelai sebesar terhadap kualitas fisik sediaan gel face. Variasi konsentrasi kedelai berpengaruh terhadap peningkatan kelembapan.
FORMULASI DAN EVALUASI GEL JAHE MERAH (Zingiber officinale Roscoe) DENGAN HPMC SEBAGAI GELLING AGENT Nita Damayanti; Lia Agustina
JURNAL PHARMA BHAKTA Vol 2 No 2 (2022): November 2022
Publisher : FAKULTAS FARMASI, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

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Abstract

Jahe merah (Zingiber Officinale Roscoe) merupakan salah satu dari temu-temuan suku Zingiberaceae yang mempunyai komponen minyak atsiri dan oleoresin paling tinggi dibandingkan jenis jahe lainnya. Kandungan dari rimpang jahe merah dapat digunakan untuk berbagai macam obat salah satunya untuk aromaterapi. Kualitas mutu fisik sediaan gel dipengaruhi oleh bahan-bahan tambahan dalam formulasi yang digunakan untuk proses pembuatannya, salah satunya adalah HPMC sebagai gelling agent . Penelitian ini bertujuan untuk mengetahui kualitas formulasi gel dari minyak atsiri jahe merah dengan melihat dari sifat fisik sediaan gel yang mengandung minyak atsiri jahe merah dengan variasi konsentrasi yaitu sebesar 2%, 4% dan 6%. Penelitian ini merupakan penelitian eksperimental. Uji mutu fisik sediaan gel meliputi uji organoleptik, uji kesukaan dan uji homogenitas. Hasil penelitian menunjukkan sediaan telah memenuhi syarat uji mutu fisik.
Co-Authors Adventa Bahing Binti Nurkayati Dewi Mega Ayu Pertiwi Dimas Aditya Dina Sectio Ficky Aulia Dyah Aryantini, Dyah Endah Retnani Wismaningsih Fenita Shoviantari, Fenita Finda Oktavianasari S.Farm. Herlinda Mawardika Ida Kristianingsih Ilham Khawarizmy Indah Susilowati Indra Fauzi Sabban Kurniawati, Evi Mia Yulianti Multia Ranum Sari Ninis Yuliati Ninis Yuliati Ninis Yuliati Ninis Yuliati, Ninis Nita Damayanti Ovie Resta Vanesha Ratna Frenty Nurkhalim Shafia Khairani Shofiatul Fajriyah Siska Kusuma Wardani, Siska Kusuma Vindy Sheila Zefia Liziarmezilia