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All Journal Pharmaciana: Jurnal Kefarmasian Naturalis : Jurnal Penelitian Pengelolaan Sumberdaya Alam dan Lingkungan PENA SAINS Jurnal Kimia Riset Journal of Health (JoH) JPM (Jurnal Pemberdayaan Masyarakat) JCES (Journal of Character Education Society) EMBRIO : Jurnal Kebidanan Jurnal Surya Masyarakat JAST : Jurnal Aplikasi Sains dan Teknologi LOYALITAS: Jurnal Pengabdian Kepada Masyarakat Health Information : Jurnal Penelitian Medicra (Journal of Medical Laboratory Science/Technology) Academia Open Madaniya Jurnal Surya Masyarakat Jurnal Pengabdian Masyarakat dalam Kesehatan Medical Scope Journal (MSJ) Jurnal Abdimas Kartika Wijayakusuma Proceedings of The ICECRS Procedia of Social Sciences and Humanities Indonesian Journal of Community Diversity and Engagement International Journal Multidisciplinary Indonesian Journal Health Science and Medicine

Jamilatur Rohmah

Universitas Muhammadiyah Sidoarjo

Author-ID : 2496246

Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Characterization of Chitosan Nanoparticles from Milkfish Scales as an Alternative Preservatives of Fresh Pangas Catfish (Pangasius hypopthalmus) Zurrotul Ilmiyah; Jamilatur Rohmah
Medicra (Journal of Medical Laboratory Science/Technology) Vol 3 No 1 (2020): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v3i1.654

Fish is a commodities that are very easy to decompose (Highly Perishable), therefore made efforts to extend the shelf life of fish by using preservatives. Preservatives that are not harmful to health are chitosan nanoparticles. The aim of this research are to know the characterization of chitosan nanoparticles from milkfish scales and their effect as fresh pangas catfish preservative by using concentration variation 1%, 2%, 3%, 4%, and 5% and optimization of storage time 12, 24, 36 , 48, 60, and 72 hours. Design in this research is experimental laboratory. Characterization of chitosan nanoparticles using FT-IT and SEM-EDX. While the effect of fresh pangas catfish preservation on chitosan nanoparticles is based on water, ash, protein, and ALT parameters. The results obtained on the characterization of chitosan nanoparticles on the identification of functional groups (FT-IR) showed absorption bands of OH groups at a peak 3450,99 cm-1, the CN snow absorption band was seen at the peak 2360,44 cm-1, the amine band of NH amine at the peak of 1639,20 cm-1 and the crystalline alcohol CO uptake band was observed at a peak of 1096,33 cm-1. The characterization results of SEM-EDX chitosan nanoparticles are round but clumped and clearly visible particle size changes. The experimental results were analyzed with two-way ANOVA statistic showing a significant effect between concentration variation and length of storage time to extend the durability of fresh pangas catfish. The best results of chitosan nanoparticles on fresh pangas catfish is at 5% concentrations at 72 hours of storage time with water value 16,4%, ash value 0,04%, protein value 0,04%, and ALT value 4,0 x 105cfu/g.

In-Vitro Sunscreen Activity of White Turi Leaf Acetone (Sesbania grandiflora (L.) Pers.) Extract: Aktivitas Tabir Surya Ekstrak Aseton Daun Turi Putih (Sesbania grandiflora (L.) Pers.) Secara In-Vitro Siroj, Muhammad Said Agil; Rohmah, Jamilatur
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 3 No. 2 (2020): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v3i2.852

Sunscreens are cosmetic preparations that protect the skin from exposure to UV radiation resulting in erythema , skin burning , aging and skin cancer. Leaf of Sesbania grandiflora (L.) Pers. contain phenolic compounds such as tannins and flavonoids which act as photoprotective . This research method is experimental with quantitative descriptive analysis. The purpose of research is to know the value of SPF, transmission erythema (% Te) and pigmentation (% Tp) of acetone extracts of Sesbania grandiflora (L.) Pers. using Spectrophotometry UV -Vis at a wavelength of 280-400 nm with intervals of 5 nm. This study variations in extract concentration were made 100, 200, 400, 600, 800 and 1000 ppm. The results showed the SPF value of extracts of all concentrations in a row was 1.9 ( minimum ); 3.6 ( minimum ); 15.9 ( moderate ); 56.3 ( high ); 133.9 ( high ); and 136.6 ( high ). The %Te value is 400 ppm ( fast tanning ), 600 ppm ( regular suntan ) and 1000 ppm ( extra protection ). The value of %Tp at all extract concentrations is included in the category total block .

Phytochemical Screening of White Turi (Sesbania grandiflora (L.) Pers.) Leaves Extract in Various Extraction Methods: Skrining Fitokimia Ekstrak Daun Turi Putih (Sesbania Grandiflora (L.) Pers.) pada Variasi Metode Ekstraksi Rohmah, Jamilatur; Saidi, Ida Agustini; Rofidah, Luthfiyah; Novitasari, Fia; Margareta, Frida Amelia
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.1395

One of the Fabaceae family that has potential as medicinal plant is the white Turi plant (Sesbania grandiflora (L.) Pers.).The purpose of this study was to determine the content of secondary metabolites which can be extracted using a various extraction methods.The extraction method used are digestion, percolation, reflux, soxhlet, infusion, and decoction extraction. The Turi plants used come from Mojosari, Mojokerto.The results of the initial phytochemical screening of white Turi leaf extract (Sesbania grandiflora (L.) Pers.) Were extracts in six extraction methods containing alkaloids, saponins and tannins.In extracts using the digestion, soxhlet, and reflux method containing steroids.Meanwhile, the four extracts from the digestion, percolation, soxhlet, and reflux methods contain phenolic.And the infusion and decoction method extracts containing flavonoids and triterpenoids. The similarity of the phytochemical test results for each extract but with different intensity results.

Efektivitas Kunyit (Curcuma longa Linn) terhadap Esherichia coli dan Bacillus subtilis: Effectiveness of Turmeric (Curcuma longa Linn) against Esherichia coli and Bacillus subtilis Rini, Chylen Setiyo; Rohmah, Jamilatur; Widyaningrum, Leni Yuroh
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 1 No. 1 (2018): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v1i1.1546

Herbal plants that serve as a drug, one of which is turmeric that has a role as an antioxidant, antimicrobial, anti-cancer, digestive disorders. Because it contains compounds curcumin and essential oils. The purpose of this research is to know the optimal concentration of dry extract of turmeric rhizome (Curcuma longa L) in inhibiting the growth of E. coli and Bacillus subtilis. This research method using diffusion agar Kirby Bauer. In this study, turmeric extract at 15% concentration had antibacterial efficacy against Bacillus subtilis (0,7 mm) greater than Escherichia coli (0,63 mm).

Kontaminasi Escherichia coli pada Makanan Jajanan di Kantin Universitas Muhammadiyah Sidoarjo: Contamination of Escherichia coli in Snacks at the Canteen of Muhammadiyah University of Sidoarjo Rohmah, Jamilatur; Rini, Chylen Setiyo; Cholifah, Siti
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 1 No. 1 (2018): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v1i1.1521

One of the places to get food is in the cafeteria. Food made in the canteen can be a cause of foodborne desesase and food poisoning if not properly disposed. The objective was to analyse the quality of food microbiology on canteen food in campus 1, 2, and 4 University Muhammadiyah of Sidoarjo. This study applied the descriptive observational which cross sectional design in canteen food stalls and sampling technique which is total sampling. Tests of canteen food samples were performed using Total Plate Count (TPC). A total of 35 samples of canteen foods from the campus canteen. The results show that positive E.coli contamination on canteen food (canteen campus 1, 2, and 4) was 25 (71.43%). There is a significant difference from the burden of microbial samples of canteen food. This research was conducted to find out personal hygiene and environment, and the cleanliness of the campus should be improved and maintained.

Efektivitas Formulasi Ekstrak Daun Sirih Merah (Piper crocatum) Dengan Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb.) Terhadap Hiperglikemia Serta Histopatologi Pankreas Mencit: The Effectiveness of Formulation of Red Betel Leaf Extract (Piper crocatum) With Fragrant Pandan Leaf Extract (Pandanus amaryllifolius Roxb.) Against Hyperglycemia and Pancreatic Histopathology of Mice Handini, Hesti Dwi; Rohmah, Jamilatur
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 1 No. 2 (2018): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v1i2.1477

Diabetes mellitus (DM) is metabolism diseases characterized by hyperglycemia and change to the cell histophatology structure of pancreas. Red betel leaves (Piper crocatum) and fragnantpandanleaves (Pandanus amaryllifolius Roxb.) has compound metabolic secondary that efficacious as anantidiabetic. The aims of the study were seek the best extract formulations of red betel leaves (EDSM) and extract of fragnantpandan leaves (EDPW) to lowering blood glucose level, repair the damage of islet langerhans, and comparing the effectiveness with metformin. The research was drafted by post test only control group design using male mencit (Mus musculus) for 31 days. In this research used complete random design with 14 treatment groups, they are normal group, DM group, metfomin group, EDPW 100%group, EDSM 10%+ EDPW 90%group, EDSM 20% + EDPW 80%group, EDSM 30% + EDPW 70% group,EDSM 40% + EDPW 60% group,EDSM 50% + EDPW 50%group,EDSM 60% + EDPW 40% group,EDSM 70% + EDPW 30% group, EDSM 80% + EDPW 20% group, EDSM 90% + EDPW 10% group, and EDSM 100%group. Based on in vivo bioassay showed that metformin have a lot of lowering blood glucose levels (p<0,05) than formulation of EDSM and EDPW but not better in improving islet langerhans tissue damage and treatment DM group with EDSM 50% + EDPW 50% effective lowering blood glucose level comparable with metfomin (p>0,05) and better in improving islet langerhans tissue damage caused by alloxan diabetogenic compound.

Efektivitas Sabun Transparan Antibakteri Ekstrak Etanol Sawi Putih (Brassica Rapa Subspesies. Pekinensis) Dengan Kombinasi Coconut Oil dan Castor Oil: The Effectiveness of Antibacterial Transparent Soap Ethanol Extract of Chilli (Brassica Rapa Subspecies. Pekinensis) With a Combination of Coconut Oil and Castor Oil Khusniyah, Nurul; Rohmah, Jamilatur
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 2 No. 1 (2019): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v2i1.1488

This study aims to determine the best soap formula and to know the effect of addition of chicory extract (Brassica rapa subspecies, pekinensis) in transparent solid soap supply of antibacterial extract of chicory extract (Brassica rapa subspecies, pekinensis) to its effectiveness in Staphylococcus aureus. This research is experimental laboratory. Concentration of chicoryin soap are 0%, 25%, 50%, 75% and 100%. Anti-bacterial effectivenesstest was performed by disc method of transparent antibacterial soap of chicory extract of ethanol (Brassica rapa subspecies, pekinensis) and measured the clear zone. The analysis was performed by Two Way ANOVA test. The results of soap quality assurance standard fulfill quality standard specified by SNI in 1994 that water content test is found in formulation 6 (F6) with 75% concentration equal to 2.109%. The best free alkali test result were found in the formulation 5 (F5) with a 25% concentration of 0.041963, 50% by 0.041966 and 100% by 0.041963. The best free fatty acid test result were found in the formulation of 2 (F2) 50% concentration with free fatty acid level of 0.07852 %. For thebest pH test the conceration of 0%, 25% and 50% with pH yielded 9 and the best foam high yield test was found at 100% concentration. Result of Two Way ANOVA test with variation of extract concentration of chicory ethanol and combination of coconut oil and castor oil obtained p-value = 0.000 <0.05 which states there is real difference. The best test results are in F6 (30.6833 mm). Two Way ANOVA test results showed that transparentsolid soaps of chicory extracts had the best antibacterial effectiveness against Staphylococcus aureus with an inhibitory zone of 30.6833 mm at 100% concentration.

Formulasi dan Evaluasi Sabun Cair Ekstrak Etanol Okra (Abelmochus esculentus) serta Uji Antibakterinya: Formulation and Evaluation of Okra (Abelmochus esculentus) Ethanol Extract Liquid Soap and Its Antibacterial Test Martina, Shofie Fitria; Rohmah, Jamilatur
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 2 No. 2 (2019): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v2i2.1657

Liquid soap is a liquid form that serves to cleanse the skin. The aim of this research are to know the optimization formulation and evaluation of liquid soap extract ethanol okra ( ) and also find the best concentration of okra extract as the inhibitors against Staphylococcus . Experimental laboratory was chosen as the research design. Liquid soap consists of 5 formulations, namely formulation 1, 2, 3, 4, and 5 which consist of 0%, 25%, 50%, 75% and 100% okra concentration. The antibacterial effectiveness was tested by disc method against liquid soap extract ethanol okra ( ) and the clear zone measured. The analysis done with two-way test. The results of the evaluation of liquid soap quality was appropriate with the standard of soap quality established by SNI 1994. The best moisture value found in the formulation of 5 (F5) with 0%form of 3.54%, the best free fatty acid found in formulation 4 (F4) with a concentration of 50% of 0.07135%, the best free alkali concentration was found in formulation 2 (F2) with a 25% concentration of 0.04194%, the best pH value was presented at concentrations of 0%, 25%, and 50% with a value of 9, the best value of foam stability found in Formula 1 (F1) with a 100% concentration of 9.1, the best density (BJ) test found in Formula 4 (F4) with 0% concentration. The result of ANOVA test with variation of ethanol okra concentration obtained p-value = 0.000 <0.05 which states there was a significant difference where liquid soap extract ethanol okra has antibacterial to Staphylococcus . The best inhibitory zone test resulted in formation 5 (F5) of 14.7 mm at 100% concentration.

Heavy Metal Content in Hair at Workers in Gas Station of Sidoarjo City in 2021: Kandungan Logam Berat pada Rambut Petugas Stasiun Pengisian Bahan Bakar Umum (SPBU) di Sidoarjo pada Tahun 2021 Rohmah, Jamilatur; Miranda, Niken Anggita; Marlina, Mariany Lambertine; Fiya, Uus Ufita
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 2 (2021): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i2.1617

One of the most dominant workplaces where heavy metal contamination occurs is the Gas Station (SPBU). Gas station workers are at high risk of being exposed to heavy metals while working due to inhaling fuel that evaporates into the air and vehicle fumes due to the behavior of motorists who do not turn off the engine while waiting in line. Determination of the level of heavy metal contamination of Zn, Cu, Pb, Cd, Fe, and Cr was determined through hair clippings using the Atomic Absorbtion Spectrophotometry (AAS) method. The gas stations used in this study are SPBU X and Y in Sidoarjo. This study aims to determine the levels of heavy metals in hair and to determine the relationship between working period, age, smoking habits, and savety with heavy metal levels in gas station workers in Sidoarjo. The type of research used is descriptive cross sectional and analytical method through filling out questionnaires and correlative statistics with SPSS. The results obtained showed that the average levels of heavy metals Zn, Cu, Pb, Cd, Fe, and Cr at SPBU X were 0.232, respectively; 0.000; 0.003; 0.001; 0.464; and 0.024 mg/g. while the average levels of heavy metals Zn, Cu, Pb, Cd, Fe, and Cr at SPBU Y were 0.516, respectively; 0.000; 0.007; -0.001; 0.345; and 0.051 mg/g. It can be said that the levels of heavy metals Zn, Cu, Pb, Cd, Fe, and Cr did not exceed the specified threshold. The results of the statistical test of the correlation between the levels of heavy metals Zn, Cu, Pb, Cd, Fe, and Cr with years of service, age, smoking habits, and PPE of gas station workers were not significant (p>0.05).

Acute Toxicity Test Against Mice (Mus Musculus) On The Lempuyang Gajah Extract (Zingiber Zerumbet (L.) Roscoe Ex Sm.) With Sgot Sgpt Parameters: Uji Toksisitas Akut Terhadap Mencit (Mus Musculus) Pada Ekstrak Lempuyang Gajah (Zingiber Zerumbet (L.) Roscoe Ex Sm.) Dengan Parameter SGOT SGPT Sofi Rahayu, Bella; Rohmah, Jamilatur; Rini, Chylen Setiyo; Puspitasari
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 7 No. 1 (2024): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v7i1.1656

Lempuyang Gajah (Zingiber zerumbet (L.) Roscoe ex Sm) is a medicinal plant that has many benefits in the medicinal industry. Useful as a tonic, external medicine, anti-seizure and appetite enhancer. This study aims to determine the toxicity of the lempuyang gajah. This research uses laboratory experimental methods. The lempuyang gajah plant was obtained in the village of Terungkulon, Krian. The initial stage was the administration of lempuyang gajah extract with various doses of 4000, 5000 and 6000 mg/kg BB orally, consisting of 5 treatment groups. Parameters observed, changes in toxic symptoms, macroscopic examination and parameters of SGOT, SGPT. The results were analyzed using the One Way ANOVA test. The results of the study after giving the extract did not cause death so it was included in the non-toxic category, there were several symptoms such as weakness and seizures. The levels of SGOT, SGPT showed normal average results, statistically there was no effect (p > 0.05). Macroscopic results showed no changes or abnormalities in the liver. So that the ethanol extract of lempuyang gajah can be said to be safe for humans.

Co-Authors Achmad Noerkhaerin Putra Aini, Latifatul Andika Aliviameita Anwar, Najih Arini Siti Wahyuningsih Aziza, Vidayatul Chylen Setiyo Rini Devi Arvindani Masyitha Eni Fariyatul Fahyuni Fadilah, Fitrian Nur FATMAWATI, RIRIN Firdaus, Firyalita Sarah Fitria Ayu Prayekti, Rahmatika Fitria Eka Wulandari Fitrian Desi Prameswari Fiya, Uus Ufita Furqonati, Lili Galuh Ratmana Hanum Handini, Hesti Dwi Hidayat, Mokhamad Amirul Ida Agustini Saidi Karlia Hedit Tiana Khusniyah, Nurul Liyaajul, Pratasyah Makrufah, Makrufah Margareta, Frida Amelia Marlina, Mariany Lambertine Martina, Shofie Fitria Miftahul Mushlih Miranda, Niken Anggita Mukarromah, Rizka Aisya Novitasari, Fia NUR EFENDI Nurul Azizah NURUL AZIZAH Paramitha Amelia Kusumawardani Purwanti, Yanik Purwanti Puspitasari Puspitasari Puspitasari Puspitasari Putra, Moh. Faris Yudiana Rafhani Rosyidah Rini , Chylen Setiyo Rini, Chylen S. Rofidah, Luthfiyah Salsabila Widya Kirana Setiyo Rini, Chylen Siroj, Muhammad Said Agil SITI CHOLIFAH Siti Cholifah Sofi Rahayu, Bella Tri Chahyani Rahmawati Putri Tri Linggo Wati Vanda Rezania Wakhidah, Kemil Widyaningrum, Leni Yuroh Yuli Astutik Zulfida Ainindiyah Putri Purwanto Zurrotul Ilmiyah

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