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All Journal Damianus Journal of Medicine The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal MedScientiae
Guntur Darmawan
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : Jurnal MedScientiae

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Korelasi Status Gizi dan Risiko Fraktur pada Lansia Menggunakan FRAX Score di RS Manembo-nembo Desember 2024-Januari 2023 Kalitouw, Praysi Alicia Ferliana; Winaktu, Gracia JMT; Darmawan, Guntur
Jurnal MedScientiae Vol. 4 No. 1 (2025): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i1.3612

Abstract

Fractures in the elderly, especially hip fractures, are a serious health problem because they increase the risk of disability and death. Nutritional status is thought to play a role in fracture risk, but the relationship between the two is still unclear. This study aims to determine the correlation between nutritional status and fracture risk using the FRAX Score. This study used a cross-sectional design with 55 elderly people as a sample, selected using total sampling. Nutritional status was measured using Mid-Upper Arm Circumference (MUAC), while fracture risk was assessed using FRAX Score. Spearman correlation analysis showed a weak negative correlation between nutritional status and the risk of major fracture (r = -0.227; p = 0.096) which was not significant, but there was a significant negative correlation with the risk of hip fracture (r = -0.390; p = 0.003), meaning that the lower the nutritional status, the higher the risk of hip fracture. The conclusion of this study shows that nutritional status is associated with the risk of hip fracture, but not with overall major fracture. Further research with more sensitive methods and larger sample sizes is needed to confirm these results.
The Role of Vitamin D in Viral Infection Arsita, Elli; Laksana, Prasetya Agung; Darmawan, Guntur
Jurnal MedScientiae Vol. 5 No. 1 (2026): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v5i1.4035

Abstract

Vitamin D deficiency occurs in almost 50% of the population worldwide. The role of vitamin D in the immune system can be seen in both innate and adaptive immunity. Coronavirus Disease 2019 or COVID-19 is a new type of disease that has never been previously identified by humans. Many efforts have been made to prevent the spread of COVID-19 such as consumption of vitamin D3. This literature review aims to determine the role of vitamin D3 in COVID-19 infection. Based on a literature review of 10 studies with primary data, this literature review shows that patients with vitamin D deficiency accompanied by COVID-19 infection have higher CRP levels, clinical severity, and mortality rates. The endocrine society recommends a daily dose of Vitamin D3 supplementation in the range of 1500-2000 IU/day for adolescent adults. The administration of a single high dose of vitamin D (200,000 IU) has been shown to be ineffective in accelerating the hospitalization of COVID-19 patients in hospitals. It can be concluded that low vitamin D levels are associated with high CRP. It has been proven that Vitamin D3 plays a role in reducing mortality, preventing cytokine storms, and preventing long COVID-19 because the dose, daily requirement, comorbidities, and vitamin D deficiency are different for each individual.
Co-Authors Amaylia Oehadian Anastasia Yoveline Anastasia Yoveline Andini, Dinda Bachti Alisjahbana Bernardo, Margrette Ruth L Bernardo, Margrette Ruth L Dewi, Sumartini Dolvy Girawan Elli Arsita Emmy Hermiyanti Pranggono Gianina, Claresta Gracia JMT Winaktu hartanto hartanto Hasan Mihardja Hasan Mihardja Hikmat Permana Indah S. Widyahening Irsan Hasan Kalitouw, Praysi Alicia Ferliana Kusumawardhani, R.N. Yasmin Kusumawati, Maya Laksana, Prasetya Agung Laniyati Hamijoyo, Laniyati Liman, Lie Monica Sherine Lisda Amalia Marcellus Simadibrata Marcellus Simadibrata Miftahurachman Miftahurachman, Miftahurachman Muhammad Begawan Bestari Murdani Abdullah Murdani Abdullah Nanny Natalia M Soetedjo Nenny Agustanti Nugraha, Irvan Pranggono, Emmy Hermiyanti Ria Bandiara Ritonga, Ervita Rudi Wisaksana Saleha Sungkar Salvador, David Raymund K Salvador, David Raymund K Subong, Nestor U Subong, Nestor U Trinugroho Heri Fadjari, Trinugroho Heri Usman, Stefanie Yuliana Wijaya, Indra Yudi Wahyudi