Article Per Year (5 Year)
p-Index From 2021 - 2026
4.476
P-Index
This Author published in this journals
All Journal Biology, Medicine, & Natural Product Chemistry Medical Laboratory Technology Journal Jurnal Berkala Kesehatan Meditory : The Journal of Medical Laboratory Window of Health : Jurnal Kesehatan Health Information : Jurnal Penelitian Jurnal Abdi Insani Jurnal Pengabdian Masyarakat Sasambo Ahmar Metakarya: Jurnal Pengabdian Masyarakat Molucca Medica Pakem : Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Kepada Masyarakat Sisthana Jurnal Masyarakat Madani Indonesia Jurnal Inovasi, Pemberdayaan dan Pengabdian Masyarakat Jurnal Cendekia Mengabdi Berinovasi dan Berkarya Karya Kesehatan Siwalima Poltekita: Jurnal Ilmu Kesehatan
Theosobia Grace Orno
Poltekkes Kemenkes Kendari
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 28 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 28 Documents
Search

 1   2   3 
Podocalyxin Urine sebagai Biomarker Prediktor Nefropati Diabetik Orno, Theosobia Grace; Pelu, Jusni Ekasari
Health Information : Jurnal Penelitian Vol 15 No 2 (2023): Mei-Agustus
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v15i2.859

Abstract

Diabetes melitus tipe 2 (DMT2) merupakan penyebab terbanyak dari diabetes, terdiri atas sekitar 85% kasus. Nefropati Diabetik (ND) merupakan salah satu komplikasi dari penyakit diabetes melitus yang dapat berakhir sebagai gagal ginjal. Podocalyxin (PDX) merupakan protein yang diekspresikan dalam podosit ginjal yang berperan dalam menjaga struktur glomeruli. Desain penelitian ini dilakukan dengan metode observasional analitik dengan desain cross sectional. Jumlah sampel sebanyak 25 subjek DMT2 dengan ND dan 25 subjek DMT2 tanpa ND yang diperoleh dengan teknik sampling probability purposive sampling. Penelitian ini dilakukan di Poliklinik Endokrin, Laboratorium Patologi Klinik, Laboratorium Hasanuddin University Medical Research Center (HUM-RC) Rumah Sakit Universitas Hasanuddin Makassar. Subjek DMT2 dengan dan tanpa ND dikategorikan berdasarkan kadar Albumin/Creatinine Ratio (ACR) yang diukur menggunakan metode imunoturbidimetri dan kadar podocalyxin urine diukur menggunakan metode Enzyme-linked Immunosorbent Assay. Hasil penelitian menunjukkan Area Under Curve validitas PDX terukur pada 0,779 dengan derajat kepercayaan 0,685-0,913 (p<0,05). Nilai cut off point sebesar 0,175 ng/mL dengan sensitivitas sebesar 66,7%, spesifisitas sebesar 64,3%. Disimpulkan bahwa PDX dengan nilai kadar 0,175 ng/mL dapat digunakan sebagai biomarker prediktor ND.
Pemetaan Golongan Darah ABO dan Rhesus Masyarakat Pesisir Desa Alosi Kecamatan Kolono Kabupaten Konawe Selatan Orno, Theosobia Grace; Hikmawati, Hikmawati
Jurnal Cendekia Mengabdi Berinovasi dan Berkarya Vol 2 No 2 (2024): Mei
Publisher : Universitas Madako Tolitoli

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56630/jenaka.v2i2.610

Abstract

Desa Alosi merupakan salah satu desa di wilayah pesisir kecamatan Kolono kabupaten Konawe Selatan provinsi Sulawesi Tenggara dengan mayoritas penduduk belum mengetahui jenis golongan darahnya. Golongan darah ABO dan Rhesus merupakan golongan darah umum yang diwarisi oleh masyarakat Indonesia, bermanfaat dalam bidang kesehatan sebagai syarat utama pelaksanaan proses transfusi darah dan pencegahan komplikasi imunologis akibat ketidakcocokan. Kegiatan ini bertujuan untuk melakukan pemetaan golongan darah masyarakat desa Alosi menggunakan model door to door dengan metode pemeriksaan golongan darah slide imunoserologi. Sebanyak 152 masyarakat yang ikut serta dalam kegiatan, dengan mayoritas golongan darah O dan Rh+.  Diharapkan agar hasil kegiatan ini dapat digunakan sebagai database golongan darah pemerintah setempat untuk keperluan administrasi kependudukan maupun fasilitas layanan kesehatan dalam upaya penanggulangan kesehatan masyarakat.
Glomerular Filtration Rate in Prediabetic Subjects in Kendari City Orno, Theosobia Grace; Atmaja, Ratih Feraritra Danu; Supiati, Supiati; Hasan, Aswiro
Window of Health : Jurnal Kesehatan Vol 7 No 2 (April 2024)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/woh.vi.917

Abstract

Prediabetes is a condition of impaired blood glucose metabolism. However, it does not yet meet the criteria for diabetes mellitus, characterized by impaired fasting blood glucose (FBG) levels and the Oral Glucose Tolerance Test (OGTT). Chronic glucose intolerance can increase the workload of the kidney glomerulus in the filtration process and the tubules in the reabsorption process. The research aims to assess the Glomerular Filtration Rate (GFR) in prediabetic subjects in Kendari. This type of analytical observational research with a case-control design. The total sample was 90 samples consisting of 45 non-diabetic samples as the control group and 45 prediabetic samples as the case group. Characteristic data is presented as a frequency distribution and test data for differences between the control group and cases using an independent t-test with statistical test results said to be significant if the p-value is less than 0.05. The research results showed that the frequency distribution of subjects in the control group and cases based on gender was dominated by women, with the most extensive age range being 36-55 years. The FBG variable in the control group had a mean of 94±5.31 mg/dL, and in the case group, 110±8.09 mg/dL. The OGTT value in the control group was 118±12.78 mg/dL, and the case group was 139±23.90 mg/dL. The results of the calculation of the GFR showed a mean of 98.63±14.28 mL/min/1.73 m2 in the control group and 50.10±16.34 mL/min/1.73 m2 in the case group, different significant (p equal 0.000). There was a significant difference between GFR in the control group and the prediabetes case group. The results of the GFR assessment in the prediabetes group showed a mild decrease in renal function.
Studi Pengaruh Konsumsi Bubuk Kakao Terhadap Kesehatan Jantung Pegawai Poltekkes Kemenkes Kendari Banudi, La; Fathurrahman, Teguh; Naningsih, Hasmia; Orno, Theosobia Grace
Health Information : Jurnal Penelitian Vol 16 No 3 (2024): September-Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v16i3.1635

Abstract

Latar belakang: Penyakit jantung terjadi karena kerusakan sel otot jantung dalam memompa aliran darah keseluruh tubuh, sehingga menyebabkan kondisi jantung tidak dapat melaksanakan fungsinya dengan baik. Perbaikan pada kelaianan jantung yakni konsumsi bubuk kakao. yang banyak katekin dan epikatekin). Tujuan Penelitian untuk mengetahui Studi Pengaruh Konsumsi Bubuk Kakao Terhadap Kesehatan Jantung Pegawai Poltekkes Kemenkes Kendari. Metode Penelitian: Penelitian ini menggunakan desain eksperimen sederhana, untuk mengidentifikasi Studi Pengaruh Konsumsi Bubuk Kakao Terhadap Kesehatan Jantung. Populasi penelitian ini adalah seluruh pegawai Poltekkes Kemenkes Kendari. Pengambilan sampel dilakukan dengan teknik purposive sampling sebesar 20 orang. Setelah pemeriksaan, Sampel diberikan bubuk kakao sebesar 20 g yang dikonsumsi sebanyak 40 g tiap hari selama 7 hari konsumsi. Analisis data menggunakan paired t test. Hasil Penelitian: bahwa sebelum konsumsi bubuk kakao rata-rata nilai kolesterol sebesar 223,95 + 44,92 mg/dl dan nilai kolesterol sesudah konsumsi bubuk kakao 217,05 + 44,96 mg/dl. Hasil uji paired t test menunjukkan ada penurunan kolesterol setelah konsumsi bubuk kakao pv=0,045.  Konsumsi bubuk kakao rata-rata nilai LDL sebesar 144,42 + 28,78 mg/dl dan nilai LDL sesudah konsumsi bubuk kakao 136,74 + 34,47 mg/dl. Hasil uji paired t test menunjukkan tidak ada penurunan LDL setelah konsumsi bubuk kakao pv=0,213. Sebelum konsumsi bubuk kakao rata-rata nilai HDL sebesar 47,05 + 11,65 mg/dl dan nilai HDL sesudah konsumsi bubuk kakao 49,79 + 7.89 mg/dl. Hasil uji paired t test menunjukkan tidak ada perubahan kenaikan HDL setelah konsumsi bubuk kakao pv=0,103. Selanjutnya sebelum konsumsi bubuk kakao rata-rata nilai TG sebesar 47,05 + 11,65  mg/dl dan nilai TG sesudah konsumsi Cozika 49,79 + 7.89 mg/dl. Hasil uji paired t test menunjukkan tidak ada penurunan TG setelah konsumsi bubuk kakao pv=0,420. Kesimpulan: konsumsi bubuk kakao setelah perlakuan dapat menurunkan kolesterol total tapi tidak menurunkan LDL, tidak menaikan HDL dan tidak menurunkan TG. Saran, pada ujicoba ini hanya menggunakan waktu 7 hari sehingga perlu penambahan waktu untuk uji coba tersebut
Edukasi Efek Protektif dan Pemeriksaan Kadar High Density Lipoprotein Terhadap Perlemakan Hati Pada Masyarakat Desa Awila Kabupaten Konawe Utara Atmaja, Ratih Feraritra Danu; Orno, Theosobia Grace; Hasan, Fonnie Esther
Jurnal Inovasi, Pemberdayaan dan Pengabdian Masyarakat Vol 4 No 2 (2024): Juli- Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/jippm.v4i2.1608

Abstract

Low high density lipoprotein level is one of the dyslipidemia conditions that can increase the risk of non-alcoholic fatty liver. Public knowledge about the different functions of fat components, especially HDL, is important to reduce the incidence of fatty liver including other complications such as metabolic syndrome and cardiovascular-related diseases. This activity aims to educate the public about the function of HDL as well as determine the HDL levels of each individual. This activity involved a team of lecturers, students of Poltekkes Kemenkes Kendari, media and 40 community members of Awila Village, Molawe District, North Konawe Regency as participants. This activity includes education, interactive discussions and checking community HDL levels. From the results of the activity, the post-education post-test results increased to 65% from 45% in the pre-test. The HDL level check showed that 55% of the participants had low HDL levels. Educational activities regarding the protective function and food sources high in HDL still need to be done in the community to improve the mindset related to fat and increase public awareness of the complications caused by the disease.
Health Status of Women in Tondo Permanent Residence: Metabolic Syndrome and Quality of Life Faisal, T. Iskandar; Nurmiaty, Nurmiaty; Orno, Theosobia Grace; Kurniawan, Rahmat
Poltekita: Jurnal Ilmu Kesehatan Vol. 19 No. 1 (2025)
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v19i1.3584

Abstract

Natural disasters result in increased risk of metabolic syndrome (MetS) and reduced quality of life (QoL), especially in vulnerable groups such as women. Objective: To determine the relationship between the incidence of metabolic syndrome and the quality of life of women in Tondo Permanent Residence, Palu City. The study used a cross sectional design with a total sample of 80 women aged 18-65 years selected by purposive sampling. Data were collected through measurement of blood pressure, lipid profile, blood glucose, abdominal circumference, and quality of life questionnaire, then analyzed using chi square test and odds ratio (OR) with STATA software.  53.75% of respondents had metabolic syndrome, with significant risk factors including age, high blood pressure, total cholesterol >200 mg/dL, triglycerides >200 mg/dL, blood glucose >100 mg/dL, and abdominal circumference >80 cm. Abdominal circumference >80 cm was the strongest predictor with an OR of 77.5. Women with a better metabolic profile had a higher quality of life. There is a significant association between metabolic syndrome and the quality of life of women in Tondo Permanent Residence.
PEMBERDAYAAN MASYARAKAT SEBAGAI UPAYA PROMOTIF DAN PREVENTIF SINDROM METABOLIK PADA MASYARAKAT MELALUI PROGRAM MINCEU ANTI-MEARO Yuniarty, Tuty; Atmaja, Ratih Feraritra Danu; Orno, Theosobia Grace; Sari, Julianti Isma; Fauzi, Ahmad Zil; Putra, Ahmat Rediansya
Jurnal Abdi Insani Vol 12 No 7 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i7.2629

Abstract

Infectious diseases remain a major public health concern due to their high morbidity and mortality rates, including conditions such as cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes mellitus. Cardiovascular disease and diabetes are strongly associated with central obesity, dyslipidemia, elevated fasting blood glucose, and hypertension. Metabolic syndrome is defined as a constellation of complex metabolic abnormalities that significantly increases the risk of developing cardiovascular disease and type II diabetes mellitus. The key components implicated in the pathogenesis of metabolic syndrome include hypertension, central obesity, insulin resistance, and atherogenic dyslipidemia. This study aimed to educate the community about metabolic syndrome while simultaneously conducting early detection. The screening procedures included measurements of blood pressure, waist circumference, blood glucose levels, the measurement of total cholesterol, triglycerides, and low density lipoprotein (LDL) levels was performed using the Point of Care Testing (POCT) method. A total of 52 respondents participated in this activity, consisting of 57.7% (n=30) females and 42.3% (n=22) males. The results indicated that 92.3% (n=48) had normal blood glucose levels, 100% (n=52) had normal total cholesterol, and 21.2% (n=11) had normal LDL levels. Normal blood pressure was observed in 34.6% (n=18), while 67.3% (n=35) were found to have central obesity. Overall, 9.6% (n=5) of respondents were diagnosed with metabolic syndrome, whereas 90.4% (n=47) were not. Most respondents demonstrated metabolic risk factors such as hypertension, central obesity, and elevated LDL levels, despite having normal blood glucose and total cholesterol. These findings underscore the importance of continuous public health education and targeted interventions to prevent and reduce the prevalence of metabolic syndrome in the community.
CORRELATION BETWEEN ERITHROCYTES SEDIMENTATION RATE AND HIGH SENSITIVITY C-REACTIVE PROTEIN LEVELS IN PATIENTS WITH CORONARY HEART DISEASE Sanaky, Marisca Jenice; Grace Orno, Theosobia
Meditory : The Journal of Medical Laboratory Vol 12, No 1 (2024): Meditory, Volume 12 No. 1 Tahun 2024
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/meditory.v12i1.2469

Abstract

Coronary Heart Disease (CHD) is one of the diseases that currently threatens public health. One of the biggest triggers for CHD is atherosclerosis or narrowing of the arteries which begins with an inflammatory process. Erythrocyte Sedimentation Rate (ESR) and High Sensitivity C-reactive Protein (Hs-CRP) are acute phase proteins that will appear when an inflammatory process occurs. This study aims to assess the correlation between ESR and Hs-CRP as a marker of inflammation in CHD patients. The research method used was laboratory observation with a cross sectional design. The results of the normality test using shapiro-wilk show a value of p0.05, which means that the data is normally distributed. The average ESR value was 14.25 mm/hour in the male gender category and 26.45 mm/hour in the female gender category. The results of the Spearman-rho correlation test showed that there was a moderate correlation between LED and Hs-CRP (r=0.564). The conclusion of this study is that there is a correlation between ESR and Hs-CRP values in CHD patients. The conclusion of this study is that there is a correlation between ESR and Hs-CRP values in CHD patients.
SKRINING ANEMIA MELALUI PEMERIKSAAN LABORATORIUM PADA MASYARAKAT PESISIR DESA MEKAR KECAMATAN SOROPIA Sari, Julianti Isma; Orno, Theosobia Grace; Hasan, Fonnie Esther
PAKEM : Jurnal Pengabdian Kepada Masyarakat Vol 3 No 1 (2023): Pakem : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/pakem.3.1.7-12

Abstract

Anemia was detected from laboratory tests with hemoglobin, hematocrit and erythrocyte levels below the reference value. Anemia can be detected with Point of Care Testing method using and is effective for conducting examinations in areas with a relatively small number of health facilities. The type of method used is analytic observation. This community service aims to screen for anemia by knowing hemoglobin and hematocrit levels. The results of the examination showed that from 50 respondents, the average hemoglobin level had a result below the reference value of 12.0 – 17.0 g/dl and the hematocrit value having a result below the reference value of 37-48%. The average hemoglobin value for men is 12.0 g/dl and for women is 11.9 g/dl. The average hematocrit value for both men and women is 35%. %. With anemia screening conducted, the public can find out hemoglobin and hematocrit levels as an effort to prevent anemia
LAYANAN PEMERIKSAAN LABORATORIUM MEDIS DASAR SEBAGAI UPAYA DETEKSI DINI SINDROM METABOLIK WARGA TIAL BARU DESA SULI KECAMATAN SALAHUTU Orno, Theosobia Grace; Madiuw, Devita; Lenderts, Elita Stephanie
PAKEM : Jurnal Pengabdian Kepada Masyarakat Vol 4 No 1 (2024): Pakem : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/pakem.4.1.38-45

Abstract

Sindrom metabolik merupakan faktor predisposisi terjadinya diabetes melitus dan penyakit jantung yang ditandai dengan obesitas sentral, hipertensi, hiperglikemia, serta dislipidemia. Kegiatan ini bertujuan untuk memberikan layanan pemeriksaan laboratorium medis dasar untuk deteksi sindrom metabolik bagi warga Tial Baru Desa Suli Kecamatan Salahutu. Sesuai kriteria National Cholesterol Education Program- Adult Treatment Panel III Cholesterol disimpulkan bahwa sebanyak 59% warga mengalami sindrom metabolik berdasarkan pada hasil pengukuran lingkar perut, tekanan darah serta kadar glukosa darah puasa. Disarankan kepada masyarakat untuk memperbaiki pola hidup dengan cara mengontrol asupan gizi, mengatur pola aktivitas fisik serta manajeman stres.
Co-Authors Afni Juhairia Laisouw Ahmat Rediansya Putra Ahmat Rediansya Putra Andi Alfian Zainuddin Anita Rosanty Anita Rosanty Anita Rosanty, Anita Aswiro Hasan Aswiro Hasan Atmaja, Ratih Feraritra Danu Aulia Rachma Banudi, La Dene Fries Sumah Devita Madiuw Dian Thiofany Sopacua Elita Stephanie Lenderts Fonnie Esther Hasan Handayani Malik Hasan, Aswiro Hasan, Fonnie Esther Hasan, Zulfikar Ali Hikmawati Hikmawati Himawan Sanusi Irfan Idris Julianti Isma Sari Lenderts, Elita Stephanie Liong Boy Kurniawan Lisse Pattipeiluhu Mansyur Arif Marisca Jenice Sanaky Naningsih, Hasmia Nurmiaty, Nurmiaty Pattipeiluhu, Lisse Pelu, Jusni Ekasari Putra, Ahmat Rediansya Rahmat Kurniawan Ratih Feraritra Danu Atmaja Ratih Feraritra Danu Atmaja Ratih Feraritra Danu Atmaja Ratih Feraritra Danu Atmaja Rehena, Zasendy Reni Yunus Sari, Julianti Isma Sarita, Sultina Sinthia Rosanti Maelissa Sopacua, Dian Thiofany Supiati Supiati Supiati Supiati T. Iskandar Faisal Tahapary, Westy Teguh Fathurrahman, Teguh Tenri Esa Tuti Yuniarty Tuty Yuniarty Tuty Yuniarty Tuty Yuniarty Tuty yuniarty, Tuty Usman, Julianti Isma Sari Valensya Yeslin Tomasoa Vanny Leutualy Viere Allanled Siauta Westy Tahapary Yuyun Widaningsih Zasendy Rehena Zil Fauzi, Ahmad