Article Per Year (5 Year)
p-Index From 2021 - 2026
4.001
P-Index
This Author published in this journals
All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Berkala Ilmu Kesehatan Kulit dan Kelamin Global Medical and Health Communication Indonesian Journal of Cancer Majalah Obstetri dan Ginekologi Health Notions Syntax Literate: Jurnal Ilmiah Indonesia MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan Oto Rhino Laryngologica Indonesiana Majalah Patologi Indonesia Health and Medical Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Majalah Biomorfologi (Biomorphology Journal) Jurnal Layanan Masyarakat (Journal of Public Service) Jurnal Pengabdian Masyarakat dalam Kesehatan Indonesian Journal of Cancer Jurnal Pengabdian Masyarakat Bhinneka Jurnal Pengabdian Masyarakat Bangsa Bali Dermatology Venereology and Aesthetic Journal Folia Medica Indonesiana
KUSUMASTUTI, ETTY HARY
Departemen Patologi Anatomik, Fakultas Kedokteran, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Energy Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

Published : 37 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 37 Documents
Search

 1   2   3   4 
Diagnosis of Kaposi’s sarcoma Alvian Arifin Saiboo; Dwi Murtiastutik; Etty Hary Kusumastuti; Putri Halla Shavira
Bali Dermatology Venereology and Aesthetic Journal BDVJ - Vol. 5 No. 2 (December 2022)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/9hqvm129

Abstract

Kaposi’s sarcoma has a picture reminiscent of several skin conditions, so further testing is needed to show the diagnosis of Kaposi’s sarcoma. Lymphatic endothelium cells infected with KSHV or human herpesvirus 8 form the basis of Kaposi’s sarcoma (KS), a multicentric tumor (HHV-8). These macules and plaques might be purple, reddish-blue or dark brown-black in color. KS is distinguished by this look.” Inflamed, ulcerated nodular lesions are common. They are neither unpleasant or uncomfortable, and the overlying skin or underlying tissues seldom die as a result of them. The gold standard examination in establishing the diagnosis of KS is histopathology. Several techniques that can be used for histopathological tissue retrieval are punch biopsy, shave biopsy, excision biopsy and incision biopsy. Immunohistochemical examination can also be performed to rule out the differential diagnosis. Immunohistochemical examination that we can do is with LANA-1, CD 34, CD 31, D2-40. Diagnosis of Kaposi’s sarcoma is difficult to diagnose only from a clinical picture, so similar diagnoses, i.e. histopathological and immunohistochemical examinations, are required.
Optimalisasi Deteksi Dini Kanker Serviks Melalui Peningkatan Kapasitas Tenaga Kesehatan dan Edukasi Komunitas di Puskesmas Ngariboyo, Kabupaten Magetan Sari, Aditya Sita; Rahniayu, Alphania; Kurniasari, Nila; Rahaju, Anny Setijo; Mastutik, Gondo; Fauziah, Dyah; Kusumastuti, Etty Hary; Susilo, Imam; Sandhika, Willy; Mustokoweni, Sjahjenny; Ilmiah, Khafidhotul
Jurnal Pengabdian Masyarakat Bhinneka Vol. 4 No. 1 (2025): Bulan September
Publisher : Bhinneka Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58266/jpmb.v4i1.549

Abstract

Latar belakang: Kanker serviks merupakan masalah kesehatan global dengan angka morbiditas dan mortalitas yang tinggi, termasuk di Indonesia. Deteksi dini melalui pemeriksaan Pap smear masih menjadi metode yang sering dipakai, namun akurasi hasilnya sangat bergantung pada teknik pengambilan sampel yang adekuat. Tujuan: Pengabdian masyarakat ini bertujuan untuk Meningkatkan pengetahuan dan keterampilan tenaga kesehatan di Puskesmas Ngariboyo dalam teknik pengambilan sediaan Pap smear yang memadai, dan Meningkatkan kesadaran dan pengetahuan masyarakat tentang deteksi dini kanker serviks. Metode: Metode kegiatan terdiri dari dua bagian utama. Pertama, pelatihan bagi tenaga kesehatan yang meliputi webinar dan praktikum offline untuk mengukur adekuasi sediaan berdasarkan Sistem Bethesda. Kedua, penyuluhan dan skrining offline bagi 95 warga dan 101 peserta pemeriksaan Pap smear. Hasil Hasil pelatihan menunjukkan peningkatan signifikan pengetahuan tenaga kesehatan (nilai 80-100 meningkat dari 58,82% menjadi 82,35%). Penyuluhan juga berhasil meningkatkan pengetahuan masyarakat (nilai 80-100 meningkat dari 80% menjadi 94,74%). Hasil skrining menunjukkan 100% sediaan adekuat dan 100% hasil Negative for Intraepithelial Lesion or Malignancy (NILM). Kesimpulan: Disimpulkan bahwa program ini efektif dalam meningkatkan kapasitas tenaga kesehatan dan kesadaran masyarakat, sekaligus menghasilkan data dasar skrining kanker serviks yang berkualitas bagi wilayah Ngariboyo.
Analysis of the expression of fas/cd95 and hsp70 in low and high grade urothelial cell carcinoma of the bladder Heryanto, Heryanto; Kusumastuti, Etty Hary; Rahaju, Anny Setijo
Folia Medica Indonesiana Vol. 53, No. 4
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Urothelial Cell Carcinoma (UCC), also called transitional cell carcinoma of the bladder, is the most common malignancy in urinary tract. The prognosis of this disease is highly dependent on the histological grading at diagnosis. Fas/CD95 has a role in apoptotic process, whereas HSP70 has an antiapoptotic role. This study aimed to analyze the expression of Fas/CD95 and HSP70 in low grade and high grade urothelial cell carcinoma in the bladder. This was an analytic observational study with cross sectional approach. Population and sample were paraffin blocks of urothelial cell carcinoma in the Laboratory of Anatomic Pathology, Dr. Soetomo Hospital, Surabaya in the period of January 2011-December 2016. Each grading of urothelial cell carcinoma was randomly sampled. Immunohistochemystry with Fas/CD95 and HSP70 were performed. Expression of Fas/CD95 and HSP70 were assessed semiquantitatively. Expression of Fas/CD95 and HSP70 were analyzed using Mann-Whitney test and Spearman test. The results showed there was significant different in expression of Fas/CD95 and HSP70 in low and high grades in urothelial cell carcinoma. There was no significant correlation between the expression of Fas/CD95 and HSP70 in urothelial cell carcinoma. As a conclusion, the role of CD95 and HSP70 expression can be useful as marker for the diagnosis, especially in the determination of the grade of differentiation.
The Histopathological Features of Syphilis and Its Mimickers Purnamasari, Indah; Hidayati, Afif Nurul; Kusumastuti, Etty Hary; Effendy, Isaak
Folia Medica Indonesiana Vol. 59, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Highlights: • The importance of having a strong suspicion for syphilis and maintaining close contact between dermatologists and pathologists cannot be understated. • Understanding the clinical relationship and histopathological features of syphilis is crucial for accurate diagnosis and distinction from its histopathologic mimickers. Abstract: Settings Syphilis, also known as "the great imitator," is a sexually transmitted infection with a variety of clinical symptoms and histopathological similarities to other infectious diseases. Public health concerns about syphilis have grown significantly. Since 2000, there has been an increase in syphilis prevalence in the United States, with a 17.6% increase from 2015 to 2016. From 2000 to 2019, the number of syphilis cases throughout Asia increased from 0.9% to 30.9%, whilst the number of cases in Indonesia decreased from 22.5% to 14.4%. Specific serological tests for syphilis can usually detect and confirm the diagnosis and offer follow-up care in most cases. However, in certain instances, the clinical characteristics discovered during testing can be identical to those of other diseases, which may lead to inconsistent diagnosis. Considering that the diagnostic pathology is pertinent to the clinical circumstances, a histopathological investigation may be useful for differentiating syphilis mimickers. Pathology is essential for identifying potential syphilis patients with ambiguous clinical symptoms. This study's purpose was to assist dermatologists and pathologists in identifying "mimickers" that require a biopsy and in determining the correct diagnosis and treatment coutsed based on etiology.
Accuracy of Fine Needle Biopsy (FNAB) in Lymph Nodes Tuberculosis Sari, Aditya Sita; Kurniasari, Nila; Rahaju, Anny Setijo; Kusumastuti, Etty Hary; Rahniayu, Alphania
Health and Medical Journal Vol. 8 No. 1 (2026): HEME January 2026
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v8i1.1875

Abstract

Introduction: Tuberculosis (TB) is an infection caused by Mycobacterium Tuberculosis (Mtb) that can attack various organs such as peripheral lymph nodes. Fine needle aspiration biopsy (FNAB) is often used as one of the modalities of diagnosis of lymph node tuberculosis to determine the management of patients. Objective: The objective of this study is to evaluate the accuracy, efficiency, and effectiveness of FNAB in diagnosing lymph node tuberculosis. The findings will assess whether FNAB can be adopted as a standard diagnostic and management tool for patients with this condition. Methods: This is an observational analytic cross-sectional study in the population of patients with suspicion of lymph node tuberculosis at the Anatomical Pathology Unit of Dr. Soetomo General Academic Hospital Surabaya in one year period. FNAB examination was performed with Modified Grunwald Giemsa (MGG) and Ziehl Nielsen (ZN) staining to detect AFB (Acid Fast Bacilli) organisms, as well as PCR (Polymerase Chain Reaction) of peripheral blood. The results were analysed using Chi square statistic test. Results: The sensitivity, specificity, Positive Predictive Value (PPV) and Negative Predictive Value (NPV) of FNAB examinations were 100%, 33%, 59% and 100%, respectively, meanwhile the sensitivity and specificity of PCR peripheral blood examination were 8% and 70% compared to the ZN examination of the FNA aspiration material. Conclusion: FNAB had a higher sensitivity than PCR of peripheral blood to detect Mycobacterium Tuberculosis infection; on the other hand PCR of peripheral blood had a higher specificity than FNAB to detect Mycobacterium Tuberculosis infection.
Analisa Ekspresi E-cadherin dan MMP-2 pada Karsinoma Sel Skuamosa Laring Andayani, Tuti; Kusumastuti, Etty Hary; Rahaju, Anny Setijo
Majalah Patologi Indonesia Vol 27 No.3, September 2018
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar belakangKarsinoma laring merupakan keganasan kedua terbanyak pada kepala dan leher dan lebih dari 90% berupa karsinoma sel skuamosa (KSS). Penanganan kanker laring berkaitan dengan diagnostik dan terapi, terutama ketika penyakit ini terdiagnosis pada stadium lanjut dengan keterlibatan kelenjar getah bening (KGB). Metastasis KSS pada KGB melibatkan beberapa protein yang berperan dalam adhesi sel seperti E-cadherin dan matrix metalloproteinase2 (MMP-2). Pada penelitian ini dilakukan analisis ekspresi E-cadherin dan MMP-2 pada KSS laring untuk menilai peran kedua protein tersebut dalam proses metastasis ke KGB leher.MetodePenelitian observasional analitik dengan pendekatan cross sectional. Sampel penelitian adalah blok parafin KSS laring di Departemen Patologi Anatomik RSUD Dr. Soetomo Surabaya selama Januari 2013-Desember 2014. Tiga puluh sampel terdiri atas dua kelompok, yaitu metastasis KGB dan non metastasis KGB dan dilakukan pemeriksaan imunohistokimia dengan antibodi E-cadherin dan MMP-2. Ekspresi E-cadherin dan MMP-2 dinilai secara semi kuantitatif dan dianalisis dengan tes Mann-Whitney, sedangkan korelasi antara ekspresi E-cadherin dan MMP-2 dengan tes Spearman.HasilTidak terdapat korelasi yang signifikan antara ekspresi E-cadherin dan MMP-2 pada KSS laring. Tidak terdapat perbedaan ekspresi E-cadherin dan MMP-2 yang signifikan antara KSS laring metastasis dan non metastasis ke KGB leher.KesimpulanEkspresi E-cadherin dan MMP-2 tidak berbeda bermakna karsinoma sel akuamosa laring tanpa dan metastasis ke KGB leher. Tidak terdapat korelasi ekspresi E-cadherin dan MMP-2 pada kejadian metastasis KGB leher pada KSS laring.
Analisis Ekspresi BRAF dan TERT pada Kasus Papillary Thyroid Carcinoma Berdasarkan Stratifikasi Risiko ATA Cempaka Harsa Sekarputri,; Etty Hary Kusumastuti,; Gondo Mastutik
Majalah Patologi Indonesia Vol. 29 No. 3, September 2020
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v29i3.444

Abstract

BackgroundPapillary thyroid carcinoma (PTC) is the most common malignancy in thyroid, accounting for more than 80% of all thyroid cancer.Rrecurrences of the disease reach 30% cases. It has been widely observed that BRAF and TERT is associated with aggressivenessbehaviors in human cancer. Both are involved in the pathogenesis of PTC that may be used as targets for new therapies. AmericanThyroid Association (ATA) risk stratification can define the risk of recurrence in PTC. No marker has been found to determine therisk of PTC recurrence. The purpose of this study is to analyzed BRAF and TERT expression in ATA risk stratification system inPTC classic variant samples.MethodsThe methods of this study is an analytical observational study with cross sectional approach, conducted on 56 samples of PTCclassic variant selected from Department of Anatomical Pathology Dr. Soetomo General Hospital between January 2015-December2017 by determined criteria in ATA risk stratification groups of low risk, intermediate risk and high risk. The expression BRAF andTERT observed using immunohistochemical staining of Santa Cruz monoclonal antibody.ResultsThe result for each group based on ATA risk stratification groups of low risk were 13 samples (23.20%), intermediate risk were 25samples (44.62%) and high risk were 18 samples (32.12%).The correlation was assessed with Spearman’s rho correlation test. There is significant correlation BRAF (p=0.004) with a value ofr=0.374 and TERT(p=0.032) with a value of r=0.287 for ATA risk stratification.ConclusionBRAF and TERT expression showed significant correlation to ATA risk stratification in classic variant PTC.
Co-Authors Afif Nurul Hidayati Afif Nurul Hidayati, Afif Nurul Alim, Kenny Dion Alphania Rahniayu Alvian Arifin Saiboo Ami Ashariati Andayani, Tuti Anggoro, Rovi Anny Setijo Rahaju, Anny Setijo Ariani, Grace As'ad Naufal Askandar Tjokroprawiro Cempaka Harsa Sekarputri Cita Rosita Sigit Prakoeswa Damayanti Damayanti Dewi Sartika A. W. Dian Yuliartha Lestari Djuanda, Stephanie Natasha Dwi Murtiastutik DYAH FAUZIAH, DYAH Effendy, Isaak Falerina, Rosa Fira Soraya Ghaib, Husnul Gondo Mastutik Hasan Hasan Heriyawati, Heriyawati Heryanto Heryanto Heryanto Heryanto Ilmiah, Khafidhotul Imam Susilo Indah Nur Damayanti Indah Purnamasari Indah Purnamasari Indra Yulianti Isaak Effendy Karindra Amadea Susetiyo Khafidhotul Ilmiah Lies Mardiyana, Lies Lutfia Ariska Ramadhani Nadya Divina Baihaqi Nadya Wulandari Alshanti Nila Kurniasari Nur Imroatul Mursyidah Nurdhani Hi Djafar PRIMA ROOSANDRIS Putri Halla Shavira Qonitatillah, Ana Ramadhan, Farhan Ubaidillah Ridholia Ridholia Ridholia, Ridholia ROOSANDRIS, PRIMA Rovi Anggoro S.Pd. M Kes I Ketut Sudiana . Sahudi Sahudi Sari, Aditya Sita Sensusiati, Anggraini Dwi Sjahjenny Mustokoweni, Sjahjenny Susetiyo, Karindra Amadea Sutrisno, Sutrisno Trisniartami Setyaningrum Tuti Andayani Ummi Maimunah Widyaningrum, Saraswati Widyoningroem, Anita Willy Sandhika Windy Ayustyas Trisna Wiratama, Priangga Adi Yenny Meilany Sugianto Yusuf, Muhtarum Yusuf, Muhtarum