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Sequelae Tuberkulosis dengan Hemoptisis Rekurens: [Recurrent Hemoptysis in Sequelae Tuberculosis] Desilia Atikawati; Isnin Anang Marhana
Jurnal Respirasi Vol. 1 No. 3 (2015): September 2015
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (302.349 KB) | DOI: 10.20473/jr.v1-I.3.2015.88-93

Abstract

Background: Various sequelae and complications can occur in treated or untreated tuberculosis (TB). One of complications in  the lungs is hemoptysis, due to alterations of pulmonary vascular structure. Hemoptysis as TB sequelae can happen recurrently and  massively. Case: We present the case of 31 year old man with recurrent hemoptysis since 1 year before admitted to hospital. Patient had  a history of receiving antituberculosis drugs (ATD) before. Chest xray showed pleural thickening and opacity in right hemithorax with  signs of loss of volume. Bronchoscopy showed active bleeding in lateral segment of right lung middle lobe. Chest CT showed destroyed  right lung. Hemoptysis still existed despite the given conventional therapy, thus patient underwent pulmonary arteriography. The result  showed extensive vascular abnormality in the right lung with arteriovenous fistula on right bronchial artery and aneurysmatic branch of  superior bronchial and inner intercostal arteries. During the procedure, there was no active bleeding, so bronchial artery embolization  was adjourned. Patient then experienced recurrent and massive hemoptysis, thus right pneumonectomy was done. During the surgery,  there was uncontrolled active bleeding that caused the patient’s death. Conclusion: This case illustrates recurrent hemoptysis as one of  severe TB sequelae. In extensive pulmonary vascular abnormality, pneumonectomy can cause uncontrolled active bleeding. Bronchial  artery embolization can be used as an alternative to treat patients with recurrent homptysis.
Kepositifan Induksi Sputum NaCl 3% dan Teknik Broncho Alveolar Lavage pada Pneumocystis Pneumonia: [Positivity Result of Nebulized NaCl 3% versus Bronchoalveolar Lavage in Pneumocystis Pneumonia] Isnin Anang Marhana; Retna Dwi Puspitarini
Jurnal Respirasi Vol. 2 No. 3 (2016): September 2016
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (113.621 KB) | DOI: 10.20473/jr.v2-I.3.2016.69-75

Abstract

Background: Pneumocystis pneumonia (PCP) is a major cause of morbidity and mortality in patients immunocompromised. The incidence of PCP in HIV are 0.3 cases per 100 person years with mortality 63.6%. The diagnosis of PCP experiencing difficulties because of the causative organism can not be cultured. Several attempts were carried out to obtain a representative sample sputum through induced sputum and bronchoalveolar lavage. This study compared the use of induced sputum and bronchoalveolar lavage (BAL) in the diagnosis of PCP. Methods: From September, 2015, to February, 2016, HIV-positive patients 21 to 65 years old were evaluated at UPIPI ward, Soetomo hospital with suspicion of PCP based on clinical and radiological findings. Sputum induction and BAL was done for Giemsa staining. Result: Thirteen subjects with a mean age of 40, with 11 male (84.6%). All subjects with chief complain shortness of breath and common complain cough with hard to expetorate. Most frequent risk factors was freesex. Mean of subjects received treatment cotrimoxazole is 3.5 days. Six subjects have been treated with ART. Mean of LDH serum was 554.62 ± 376.707 U/l. Interstitial infiltrate was the most frequent radiological pattern (76.9%). Most bronchoscopy examinations showed normal results (84.6%). Both Giemsa staining from induced sputum and BAL showed no positive results. Conclusion: All Giemsa staining from both induced sputum and BAL can not be compared due to no positive result.
Faal Paru Difusi : [Lung Diffusion: A Review] Alfian Nur Rosyid; Isnin Anang Marhana
Jurnal Respirasi Vol. 4 No. 2 (2018): Mei 2018
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (804.205 KB) | DOI: 10.20473/jr.v4-I.2.2018.61-70

Abstract

Diffusion capacity is useful for measuring ability of pulmonary microcirculation to transfer oxygen and carbon dioxide from alveoli to capillaries. Physiological examination of diffusion is a continuation of physiological examination of ventilation. Diffusion capacity is measured by DLCO (Diffusing capacity for Carbon Monoxide). Measurement of oxygen diffusion capacity directly is very difficult so that indirect methods are used using carbonmonoxide (DLCO). Diffusion capacity of oxygen is equivalent to DLCO multiplied by 1.23. Normal value of DLCO is 20-30 ml/minute mmHg. Some factors that affect DLCO are Hb levels, COHb in smokers, and alveolar volume. Some techniques for measuring DLCO include Steady-state, Three-equation Single-breath, Nitrogen Washout, and Intra-breath DLCO. This test is indicated in pulmonary parenchymal disease (pulmonary fibrosis, asbestosis, sarcoidosis, interstitial lung disease), cystic fibrosis, pulmonary hypertension, and pulmonary bleeding. DLCO is increased in asthma patients, obesity, polycythemia, intraalveolar bleeding, and right-left heart shunting. DLCO is decreased in emphysematous lung patients, pulmonary post resection, bronchial obstruction, multiple pulmonary embolism, anemia, idiopathic pulmonary fibrosis, asbestosis, sarcoidosis, vascular collagen disease, hypersensitive pneumonitis, and alveolar proteinosis.
Seorang Wanita Mengalami Aspirasi Barium Dengan Komplikasi Pneumonia : [Barium Aspiration Complicating Pneumonia in a Woman: A Case Report] Isnin Anang Marhana; Adhari Ajipurnomo
Jurnal Respirasi Vol. 5 No. 1 (2019): Januari 2019
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (552.84 KB) | DOI: 10.20473/jr.v5-I.1.2019.5-9

Abstract

Background. Barium aspiration is one of rare major complication of esophagography. Aspiration pneumonia occurs about 40% without clinical symptom and can cause 30% of dead. Case. A female 62 years old choked a mount of barium when swallowing barium liquid in esophagography procedure. There was ronkhi on lower left haemithorax and granuler pattern on left paracardial impressed the rest of barium in chest x-ray photo. Patient suffered symptom of infection in eight days evaluation with infiltrate and rest of barium from chest x-ray photo. Microbiology examination of bronchus lavage founded pathogen microbe Burcholderia Gladioli and Pseudomonas and containing 1,22 mg/L of barium. Discussion. Barium aspiration can occur in esophagography procedure in extreme age. Chest x-ray and Computed Tomography can be used as primer tool to diagnose and evaluate barium aspiration which imaging hiperdens pattern due to barium with high atomic number (56). Prognosis of aspiration barium can be affected by the quantity and density of barium liquid which is choked and comorbid factor in patient. Barium aspiration mixed with secrete of oropharing which containing colony of pathogen can cause penumonia as disease complication. There is still no guideline for barium aspiration management, but bronchoscopy is recommended by many clinician. Conclusion. Pneumonia occur when aspiration barium mixed with secrete oropharing which containing colony of pathogen. Chest x-ray and CT scan can be used as tool to diagnose barium aspiration. Bronchoscopy is recommended to diagnose and to manage barium aspiration. When pneumonia is suspicious, antibiotic with anaerob activity is recommended given.
Profil Pasien Kanker Paru Primer yang Dirawat Inap dan Rawat Jalan di Rumah Sakit Umum Daerah Dr Soetomo Surabaya : [Profile of Primary Lung Cancer Patients in Dr. Soetomo General Hospital Surabaya] Muhammad Rudy Chairudin; Isnin Anang Marhana; Dyah Erawati
Jurnal Respirasi Vol. 5 No. 3 (2019): September 2019
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (325.77 KB) | DOI: 10.20473/jr.v5-I.3.2019.65-71

Abstract

Background: Lung cancer is still one of the biggest contributors to cancer deaths. GLOBOCAN in 2012 reported that lung cancer causes 30% of cancer deaths in men and 11.1% in women. Objective: The purpose of this study was to determine the profile of lung cancer in the General Academic Hospital Dr. Soetomo.Method: This research uses a descriptive observasional type by taking one time  through medical record data from 186 primary lung cancer patients in Dr. Soetomo Hospital during January to December 2017. Results: Men (70.4%) more than women (29.6%). The most age group is 51-60 years (35.5%). Men and women suffer the most from adenocarcinoma (78.6% and 87.3%). Most jobs are private employees (38.2%). Most education is high school (70.4%). The most of patients live in East Java (97.3%) and the most specific are in Surabaya (39.2%). Most Histopathology is non-small cell lung cancer (95.9%) with adenocarcinoma is the most common type (81%). Lung cancer with small cell and non small cell type are mostly found in stage IV (82.3%) and extensive stage (3.8%). Local metastases are mostly found in the contralateral lung (58.1%), and most distant metastases in the brain organ (66.7%). The most common complication is pleural effusion (42.5%). Shortness of breath is the most common symptom (59.1%). The most widely used chemotherapy drug is pemetrexed-cisplatin (17.1%). Conclusion: Primary lung cancer patients at Dr. Soetomo Regional Academic Hospital majority of men aged 51-60 years. Most local metastases are in the contralateral lung and distant metastases in the brain. Most complications are pleural effusion.
Problem Terapeutik pada Empiema Terlokulasi karena Tuberkulosis : [Theurapetic Problem in Tuberculosis Loculated Empyema] Isnin Anang Marhana; Amelia Tantri Anggraeni
Jurnal Respirasi Vol. 4 No. 3 (2018): September 2018
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (833.857 KB) | DOI: 10.20473/jr.v4-I.3.2018.86-93

Abstract

Background: Pleural effusion is the most common complication of pulmonary tuberculosis (TB). Some coexist with secondary infection could worsen clinical presentation as empyema. The incidence of pleural effusion in the early stage of empyema due to TB infection is about 31%. Somehow, untreated empyema increased in-hospital mortality. Case: A woman with unregulated diabetes mellitus was referred with organized empyema. The etiology of empyema is based on a specific process of TB infection with the ADA value of empyema fluid was 128 mg/dl. We decided to perform decortication with the result loculated empyema and bronchopleural fistula 2 cm in the inferior lobe of the right lung. The patient did not recover well. Unfortunately, fluidopneumothorax was found on a chest CT scan with contrast. Thoracotomy was performed and another bronchopleural fistula was found which length was about 1 cm in superior lobe of the right lung. Discussion: The worsening condition of the patient was caused by the occurrence of postoperative bronchopleural fistula. It was visualized as pulmonary TB with perforation of cavity nessessity. On the other hand, the condition could be worsened by the hyperglycemic state in an immunocompromised individual. Summary: Loculated empyema is a condition caused by bronchopleural fistula, the presence of a connecting cavity between pleural and bronchus which occurred less than 48 hours. Local and systemic factors might explain the development of bronchopleural fistula. Well management of the loculated empyema by knowing the etiology could improve the life survival of the patient.
Description of Stroke Patients with History of Smoking Activities Paulus Sugianto; Fatih Nugraha Abdillah; Isnin Anang Marhana; Fidiana Fidiana
AKSONA Vol. 2 No. 2 (2022): JULY 2022
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (351.451 KB)

Abstract

Highlight: Smoking raises the risk of cardiovascular disease, which can lead to stroke. A total of 33 stroke patients were selected from 579 samples. The results show some tendencies. The tendency of stroke patients with a history of activity to smoke can be explained for a number of reasons.   ABSTRACT Introduction: Smoking is a habit of Indonesian society and can be found in many places. Smoking increases the risk of cardiovascular problems, which can lead to stroke. Objective: Provides an overview of stroke patients who smoke from January to December 2020. Methods: This retrospective, descriptive research used medical records and extra data from telephone interviews with patients. A non-probability purposive sampling strategy with a total sampling method is used in this investigation. The observed variables include age, gender, number of cigarettes consumed per day, length of smoking history, type of stroke, and comorbidity. Results: The sample consisted of 33 participants chosen among 579 stroke patients. The age range of 56–65 (39.4%) was found to be the most prevalent in the 33 samples, and the sex group was dominated by men (100%). Then, for the smoking habit, the highest number of cigarettes consumed per day was dominated by the group of 9-16 cigarettes per day (45.46%). The group dominates the long smoking history with a smoking history of 30-50 years (42.43%). Ischemic stroke, also known as cerebral infarction, was the most common type (78.79%) among the samples. Of the 33 samples of stroke patients who smoked, 4 (12.12%) experienced comorbidities, including coronary heart disease, diabetes mellitus, and essential thrombocytosis. Conclusion: Several factors describe the tendency of stroke patients with a smoking history.
Pengalaman Bidan dalam memberikan Pertolongan Persalinan pada Ibu Dengan Suspect dan Terkonfirmasi Covid-19 Rita Oktavia Harahap; Dwi Izzati; Isnin Anang Marhana Anang Marhana
Jurnal sosial dan sains Vol. 2 No. 12 (2022): Jurnal Sosial dan Sains
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1819.512 KB) | DOI: 10.59188/jurnalsosains.v2i12.620

Abstract

Latar Belakang : Pada awal tahun 2020 dunia digemparkan dengan adanya virus baru yaitu coronavirus jenis baru (SARS-CoV-2), penyakitnya disebut Coronavirus disease 2019 (Covid-19). Virus ini diinformasikan pertama kali berasal dari Wuhan, provinsi Hubei, Tiongkok pada akhir Desember tahun 2019. Tujuan : Tujuan studi fenomenologi dalam penelitian ini untuk mengidentifikasi dan mengeksplorasi pengalaman bidan yang menolong persalinan pasien suspect dan terkonfirmasi Covid-19. Metode : Penelitian ini menggunakan rancangan (design) penelitian kualitatif dengan pendekatan fenomenologi yaitu suatu penelitian yang mendeskripsikan atau menggambarkan mengenai pengalaman atau fenomena yang terjadi atau dialami oleh seseorang yang bertujuan untuk memahami suatu fenomena dalam konteks sosial secara alamiah dengan mengedepankan proses interaksi komunikasi yang mendalam antara peneliti dengan fenomena yang diteliti. Hasil : Dari hasil penelitian yang telah dilakukan tentang pengalaman Bidan dalam memberikan pertolongan persalinan pada Ibu dengan suspect dan terkonfirmasi Covid-19 ada beberapa hal menurut informan yang perlu di evaluasi yaitu ruang pelayanan PONEK, penggunaan delivery chamber, ruang transisi, ruang pelayanan kurang strategis dan komunikasi interprofesional. Kesimpulan: Kesimpulan yang didapatkan penelitian kualitatif tentang “Pengalaman Bidan dalam Memberikan Pertolongan Persalinan pada Ibu dengan suspect dan terkonfirmasi Covid-19 : Studi Kualitatif Fenomenologi” adalah persepsi bidan, persiapan dalam melakukan pertolongan persalinan, pertolongan persalinan oleh bidan, perubahan adaptasi, sistem pendukung dalam pelayanan, harapan bidan dan evaluasi pelayanan.
Neutrophil-To-Lymphocyte Ratio (NLR) pada Pasien Kanker Paru dengan Riwayat Merokok dan Tidak Merokok Annisa Nurul Husna; Isnin Anang Marhana
Cerdika: Jurnal Ilmiah Indonesia Vol. 2 No. 2 (2022): Cerdika: Jurnal Ilmiah Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (324.727 KB) | DOI: 10.59141/cerdika.v2i2.338

Abstract

Latar Belakang: Kanker paru-paru merupakan salah satu kanker yang paling banyak terjadi, telah menyebabkan 1/3 kematian akibat kanker pada pria. Merokok sebagai salah satu faktor risiko dapat menyebabkan respon inflamasi yang kemudian meningkatkan nilai neutrofil-limfosit rasio (NLR). Namun, tidak semua pasien memiliki riwayat perokok. Tujuan: Penelitian ini bertujuan untuk membandingkan perbedaan nilai NLR pada pasien dengan riwayat perokok dan bukan perokok. Metode: Penelitian ini menggunakan Uji Mann Whitney untuk mendapatkan hasil nilai NLR secara statistik setelah dilakukan pengumpulan data sekunder berupa neutrofil dan limfosit sebagai data sekunder dari rekam medis. Hasil: Terdapat 33 pasien dengan riwayat perokok dan bukan perokok. 15 pasien (22,73%), berasal dari kelompok usia 56-60 tahun. Ada 38 pasien laki-laki dan 28 pasien perempuan. Adenokarsinoma memiliki angka kejadian tertinggi (83,33%) dan semua pasien berada pada stadium IV selama pengambilan data. Sebagian besar pasien (45,45%) mengeluh mengalami nyeri dada. Nilai NLR untuk pasien dengan riwayat perokok adalah 4,94 dan 3,76 untuk bukan perokok dengan p=0,13. Kesimpulan: Terdapat perbedaan nilai NLR pada pasien kanker paru dengan riwayat perokok walaupun perbedaan tersebut tidak bermakna secara statistik.
Correlations between Maternal Age, Education, and Knowledge on the Compliance of COVID-19 Vaccine Uptake in Children Aged 6 – 11 Years Supiatun.M, Lilis Sri; A’yuni, Zera Qurrota; Marhana, Isnin Anang; Husada, Dominicus
Journal of Maternal and Child Health Vol. 7 No. 6 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (34.585 KB) | DOI: 10.26911/thejmch.2022.07.06.10

Abstract

Background: The coverage rate for giving the COVID-19 vaccine to children in several regions of Indonesia is still in the low category, one of which is in Abeli District, Kendari City. One of the factors that can affect the low administration of vaccines to children is due to mothers' concerns about their children so they are hesitant and reluctant to be given the COVID-19 vaccine. This study aims to analyze the relationship between age, education, and knowledge of mothers with compliance with the COVID-19 vaccine in children aged 6-11 years in Abeli District, Kendari City. Subjects and Method: A cross-sectional study was conducted in Abeli District, Kendari City, from August to October 2022. A total of 90 subjects were selected using a proportionate stratified random sampling technique. The dependent variable is adherence to giving the COVID-19 vaccine to children. The independent variables include age, education, and mother's knowledge. The instrument used is a questionnaire. Data analysis used was the Chi Square test. Results: Adherence to maternal COVID-19 vaccine administration increased with knowledge (OR= 3.57; 95% CI= 1.46 to 8.75; p= 0.007). Meanwhile, age (OR= 0.34; 95% CI= 0.14 to 0.83; p= 0.003) and education (0.31; 95% CI= 0.12 to 0.31; p= 0.020) reduced maternal adherence in administering the COVID-19 vaccine to children. Conclusion: There is a significant relationship between age, education, and mother's knowledge with compliance with the COVID-19 vaccine in children aged 6-11 years in Abeli District, Kendari City. Keywords: maternal age, maternal education, knowledge, COVID-19 vaccine. Correspondence: Lilis Sri Supiatun Mamesah. Midwifery Program Study, Faculty of Medicine, Universitas Airlangga, Indonesia. Jl. Mayjen Prof. Dr. Moestopo No.47, Pacar Kembang, Tambaksari, Surabaya 60132, East Java, Indonesia. Email: lilis.sri.supiatun-2019@fk.unair.ac.id. Mobile: +6285333622541.