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All Journal International Journal of Electrical and Computer Engineering BERKALA FISIKA Jurnal Ilmu Dasar Jurnal Sains dan Seni ITS Jurnal Penelitian Fisika dan Aplikasinya (JPFA) Jurnal Forum Nuklir Jurnal Sains Materi Indonesia IPTEK The Journal of Engineering IPTEK Journal of Proceedings Series Jurnal Neutrino : jurnal fisika dan aplikasinya Jurnal Teknik Elektro JFA (Jurnal Fisika dan Aplikasinya) JURNAL INTEGRASI INDONESIAN JOURNAL OF APPLIED PHYSICS International Journal of Social Science and Business IJITEE (International Journal of Information Technology and Electrical Engineering) Indonesian Journal of Physics (IJP) Sewagati Journal of Engineering, Electrical and Informatics
Endarko Endarko
Departemen Fisika, Institut Teknologi Sepuluh Nopember, Surabaya 60111 Indonesia
Arts Humanities Astronomy Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Mechanical Engineering Physics Public Health Social Sciences Other

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Journal : indonesian journal of applied physics

 1 
Evaluation of Patient-Specific Quality Assurance (PSQA) using Octavius 4D in IMRT Planning for Nasopharyngeal Cancer Cases Rizki Budi Rahayu; Rustika Alifiani; Aditya Prayugo Hariyanto; Levina Almira; Endarko Endarko
INDONESIAN JOURNAL OF APPLIED PHYSICS Vol 16, No 1 (2026): April
Publisher : Department of Physics, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/ijap.v16i1.111531

Abstract

Patient-Specific Quality Assurance (PSQA) is an important procedure for verifying the accuracy of dose planning before administering radiation therapy to patients. This study investigated the effects of progressively stricter OAR constraints on fluence complexity and Patient-Specific Quality Assurance (PSQA) performance in nasopharyngeal cancer IMRT as a preliminary case-based investigation. Three IMRT plan variations were created for two patients (tumor volumes: 56.16 cm³ and 75.35 cm³) using TPS Monaco: Plan0 (no OAR constraints), Plan1 (moderate constraints), and Plan2 (strict constraints) for the parotid glands, brainstem, and spinal cord. PSQA was performed using the PTW Octavius 4D phantom with gamma index criteria of 3%/3 mm, 3%/2 mm, and 2%/2 mm, in accordance with the AAPM TG-218. All plans achieved GPR values above the 95% tolerance limit for the 3%/2 mm criterion (95.5-99.8%) and above 90% for the 2%/2 mm criterion, confirming clinically acceptable deliverability across all optimization levels. Notably, the GPR in the patient with a larger tumor volume (ID2, 75.35 cm³) did not decrease with stricter constraints. The Plan2 GPR (99.5%) exceeded the Plan1 GPR (98.5%), whereas the patient with a smaller tumor volume (ID1, 56.16 cm³), whose GPR declined consistently from Plan0 to Plan2. This divergence reveals that the relationship between OAR constraint stringency and plan deliverability is patient-specific and governed by the geometric interaction between the tumor volume and surrounding OARs; larger targets afford the TPS greater dosimetric flexibility, thereby reducing the need for narrow MLC segments even under strict constraints. These findings suggest that Octavius 4D-based PSQA serves not only as a routine delivery verification tool but also as a patient-specific plan selection tool, and that the 3%/2 mm criterion is recommended as the primary clinical evaluation parameter for nasopharyngeal IMRT.
Co-Authors Achmad Muklason Adawiyah, Siti Rabi’atul Adi Suryani Adi Suryani, Adi Adi Wardana Aditya Prayugo Hariyanto Agus Purwanto Agus Purwanto Agus Rubiyanto Ahmad Muklason Ahmad Ridlo Hanifudin Tahier Aini, Urifa Nabihal Akbar Sujiwa Akhmad Jufriadi Akhmad Muklason Akhmad Muklason Annisa, Hayfa Arfan Eko Fahrudin Ari Bangkit Sanjaya Umbu Aris Widodo Ayu Jati Puspitasari Ayu Jati Puspitasari Badri G.S Berto Mulia Wibawa Berto Mulia Wibowo Bintoro Anang Subagyo Cahyono, Yoyok Christianti, Kurnia Hastu Christiono Utomo Daffa Mahendra Darminto Darminto Darminto Darsono Darsono Diani Ainun Nisa Djuli Pontjowijono Dzulfikar, Ahmad Zaki Eli Zahrotin, Eli Ellys Kumala Pramartaningthyas Fajar, M N Farahdina, Ulya Farid Afandy, Farid Fatimah, Iim Firdhaus, Miftakhul Gani, Muhammad Roslan Abdul Gatut Yudoyono Gontjang Prayitno Hadi Santoso Haekal, Mohammad Hakim, Randy Ivanal Hariyanto, Aditya Prayugo Hariyanto, Aditya Prayugo Hena Dian Ayu Ikfina Himmaty Imam Safawi Ahmad, Imam Safawi intan permata sari Khambali, Khambali Khusnul Ain Kurriawan Budi Pranata Kurriawan Budi Pranata, Kurriawan Budi Levina Almira Maharani, Diska Mahendra Satria Hadiningrat Mahendra, Daffa Malik Anjelh Baqiya Mario, Aloysious Mashuri Mashuri Masyitatus Daris S Maylita Martani Maylita Martani Melania S Muntini Miftahuddin, Dafa Miftakhul Firdhaus Moh. Roni Hidayat Mohammad Haekal Muhammad Noer Fajar Muthmainnah, Melania Suweni Muntini Nainggolan, Andreas Nasori, Nasori Novi D. Ariyanti Nuning Armawati Nur Ichzan Aminuddin Siantang Nurrima Puspitasari Nurrisma Puspitasari Nurul Amalia Silviyanti Nurul Amalia T Nurul Amalia Triyuliana Nuzula, Nike Ika Pramartaningthyas, Ellys Kumala Prayitno, Audiena Gelung Putro, Triswantoro R Hidayat Rahmawati, Deti Rahmawati, Deti Randy Ivanal Hakim Rizki Budi Rahayu Rizqa Daniyati Rustika Alifiani S Suasmoro, dkk Santi Puspitasari Setiawan Siti Aisyah Siti Rabiatul Adawiyah Siti Zahrok Soedarso Soedarso Soedarso Soedarso Soedarso Soedarso Soedarso Soedarso Soedarso, Soedarso Suasmoro Suasmoro Sukamto, Heru Sulistyanto, Muhammad Priyono Tri Suminar Pratapa Susilo Indrawati Sutikno Triswantoro Putro Triswantoro Putro Triwikantoro Triwikantoro Ulya Farahdina Vicran Zharvan Vinda Zakiyatuz Zulfa Wardana, Humadillah Kurniadi Wardhana, Adhitya Aris Yugo Triawanto Zainuri (DOI: 10.12962/j24604682.v12i2.1331), Mochamad Zaki Suud Zulfa, Vinda Zakiyatuz