Claim Missing Document
Check
Articles

INOVASI PENUNTUN PRAKTIKUM BERBASIS GREEN CHEMISTRY PADA MATERI ELEKTROKIMIA Fajriati, Putri; Yusbarina, Yusbarina; Fatisa, Yuni; Utami, Lisa
Journal of Chemistry Education and Integration Vol 3, No 1 (2024): Journal Of Chemistry Education and Integration
Publisher : Universitas Islam Negeri Sultan Syarif Kasim Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24014/jcei.v3i1.28983

Abstract

AbstractThis research was instigated with inadequate laboratory facilities and no green chemistry based practical work guideline at school. This research aimed at finding out validity and practicality levels of green chemistry based practical work guideline on electrochemistry lesson that was designed. Design & development research (DDR) method was used in this research consisted of 4 steps—analysis, design, development, and evaluation. This research was conducted to the twelfth-grade students of MIPA at State Senior High School 1 Kampar. The research findings showed that the percentages of green chemistry based practical work guideline by media and material experts continuously were 95% and 96.43% with very valid criteria. The practicality percentages by chemistry subject teachers and student response continuously were 91.96% and 83% with very practical criteria. Based on these data, it could be concluded that green chemistry based practical work guideline was very valid and very practical to be used as a teaching material on electrochemistry lesson.Keywords : DDR, Practical Work Guideline, Green Chemistry, Electrochemistry
DESAIN DAN UJI COBA MEDIA PEMBELAJARAN MENGGUNAKAN MULTIMEDIA INTERAKTIF LECTORA INSPIRE PADA MATERI LARUTAN PENYANGGA Aisyah, Siti; Fatisa, Yuni
Journal of Chemistry Education and Integration Vol 1, No 1 (2022): Journal of Chemistry Education and Integration
Publisher : Universitas Islam Negeri Sultan Syarif Kasim Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24014/jcei.v1i1.15887

Abstract

Abstract This research aimed at developing learning media using Lectora Ispire interactive multimedia on Buffer Solution lesson and knowing the levels of validity, practicality, and student response to the learning media developed. It was a Research and Development (R&D) with Luther development model that was limited to the fifth steptesting. This research was administered at State Senior High School 9 Pekanbaru. The subjects of this research were the lecturers, Chemistry subject teachers, and students. The object was learning media using Lectora Ispire interactive multimedia on Buffer Solution lesson. Validation test questionnaire, practicality test questionnaire, student response test, and interview were the techniques of collecting the data. The data obtained then were analyzed by using qualitative and quantitative descriptive analysis techniques. The research findings showed that the media validity level was 90.5% with very valid criterion, the practicality level was 94.17% with very practical criterion, and student response to the learning media was 91.6% with very good criterion. Based on this research, it could be concluded that learning media using Lectora Ispire interactive multimedia on Buffer Solution lesson was very valid and practical, so it was proper to be used as learning media at school. Keywords : Learning Media, Lectora Inspire, Buffer Solution
PENGEMBANGAN MEDIA ELEKTRONIK LKPD BERBASIS SEARCH, SOLVE, CREATE, AND SHARE UNTUK MENDUKUNG PEMBELAJARAN KIMIA HIDROKARBON Nurmala, Septa; Fatisa, Yuni
Journal of Chemistry Education and Integration Vol 3, No 1 (2024): Journal Of Chemistry Education and Integration
Publisher : Universitas Islam Negeri Sultan Syarif Kasim Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24014/jcei.v3i1.28902

Abstract

AbstractThis research was instigated by the teacher difficulty at school in implementing the appropriate learning method in online learning process. This research aimed at designing SSCS (Search, Solve, Create, and Share) based student electronic worksheet on Hydrocarbon lesson, and finding out validity and practicality SSCS based student electronic worksheet as a teaching material on Hydrocarbon lesson. This study uses the Borg and Gall development model, which only takes 5 out of 10 stages, namely data collection, planning, product development, initial trials and initial product revisions. Preliminary testing was conducted at State Senior High School 5 Tapung by a Chemistry subject teacher and 10 of the eleventh-grade students of MIA. The data obtained were analyzed by using quantitative descriptive analysis technique.   The data analysis result of validity test showed that the percentages were 97.14% by media experts with very valid category and 92.5% by material experts with very valid category. In practicality test by teachers, the percentage was 95.71% with very practical category, and the percentage of student response test was 54% with practical enough category. However, this research still has some shortcomings so it is expected that in the future an effectiveness test will be carried out to determine the effectiveness of the media. This research is expected to help the learning process.Keywords : Student Electronic Worksheet, SSCS, Hydrocarbon
Studi Molecular Docking dan Evaluasi Farmakokinetik Senyawa Analog Pirazol Turunan Benzen-Sulfonilurea sebagai Inhibitor Enzim Aldose Reduktase and α-Glukosidase Menggunakan Pendekatan In Silico Fatisa, Yuni; Utami, Lisa; Syahri, Jufrizal; Jasril, Jasril; Lazulva, Lazulva
Jurnal Riset Kimia Vol. 15 No. 2 (2024): September
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v15i2.633

Abstract

The pyrazole scaffold modification in various chemical structures on several studies has shown various biopharmacological activities. This study aims to predict the potential inhibition of pyrazole analogs derived benzene-sulfonylurea (4A, 4B, 4E, 5A, 5C, 5D) against the α-glucosidase (3A4A) and aldose reductase (3RX2) enzymes based on a molecular docking approach using Molecular Operating Environment (MOE) 2020.0102 software and evaluate pharmacokinetic profile (ADMET). In this study, the six test compounds were obtained from previous studies that have been proven antihyperglycemic. The results showed that all the 3,5-disubstituted benzene-sulfonylurea derivative pyrazole analogs are predicted to have low inhibitory activity against the α-glucosidase enzyme. Further, all compounds showed good aldose reductase inhibitor activity and had lower binding free energy values ​​than tolrestat as the positive control (-6.82 kcal/mol). Compound 5C has the best potential inhibitory activity against the aldose reductase enzyme compared to the other test compounds, because it has the lowest binding free energy value (-8.76 kcal/mol) and interacts with important residues on the receptor forming four hydrogen bonds, namely the carbonyl group of SO2 with residues Trp111 and His110, and the carbonyl group of the amide with residues His110 and Tyr48, as well as 3 hydrophobic bonds, namely a pyrazole ring with residues Leu300, Trp219 and a furan ring with Phe122. ADMET properties of the compounds are also predicted. This information provides an opportunity for a 5C compound as an aldose reductase inhibitor agent to develop drug candidates with better and safer activities.
An Academic Analysis of Students’ Abstract Thinking Skills through the Implementation of Augmented Reality in Chemical Bonding Instruction Kurniawati, Yenni; Hartati, Yuli; Fatisa, Yuni; Yenti, Elvi; Maharani, Risma
IJIS Edu : Indonesian Journal of Integrated Science Education Vol 8, No 1 (2026): January 2026
Publisher : UIN Fatmawati Sukarno Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29300/ijisedu.v8i1.8468

Abstract

Abstract thinking skills are essential for understanding microscopic concepts in chemistry, particularly in topics such as chemical bonding. This study investigates the effectiveness of augmented reality (AR) as an innovative instructional medium that enhances students’ abstract thinking abilities within the context of chemical bonding. A mixed-method approach with a sequential explanatory design was employed, beginning with a quantitative phase followed by qualitative analysis. The participants were tenth-grade students at one of Madrasah Aliyah Negeri Pekanbaru, selected through purposive sampling. Data were collected using essay-based assessments, semi-structured interviews, and document analysis. The quantitative findings indicate a statistically significant improvement in the abstract thinking skills of students in the experimental group compared to the control group (p = 0.001), with 73.7% of students in the experimental group showing marked progress. Qualitative data further support these results, highlighting that AR facilitated students’ abilities in structural representation, abstraction, and metacognitive awareness. Additionally, AR increased student motivation and deeper engagement with the learning material. These findings suggest that integrating AR in chemistry instruction can be an effective pedagogical strategy to promote the development of abstract reasoning and 21st-century competencies.