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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Fitofarmaka Indonesia As-syifaa Jurnal Farmasi Jurnal BALIRESO ad-Dawaa : Journal of Pharmaceutical Sciences Abdimas Galuh : Jurnal Pengabdian Kepada Masyarakat Dikmas: Jurnal Pendidikan Masyarakat dan Pengabdian Pharmaceutical Reports JURNAL PENGABDIAN MASYARAKAT YAMASI Celebes Journal of Community Services Journal of Pharmaceuticals and Natural Sciences MPSJ

Asriani Suhaenah

Fakultas Farmasi, Universitas Muslim Indonesia, Makassar

Author-ID : 2645178

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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PENETAPAN KADAR FLAVONOID FRAKSI ETIL ASETAT DAUN KARET KEBO (Ficus elastica) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Suhaenah, Asriani; Pratama, Mamat; Amir, A. Hesti Wulandasari
Jurnal Ilmiah As-Syifaa Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i1.761

Rubber plant (Ficus elastica) is a plant that has been widely used as traditional medicine. The leaves of this plant are used as medicine for coughing up blood, laxative urine, relieving pain and improving blood circulation. Various kinds of properties and benefits of the rubber plant (Ficus elastica) cannot be separated from Â the compounds contained in it such as saponins, polyphenols, and flavonoids. Â The aims of this research is to determine the flavonoid total content in the ethyl acetate fraction of the rubber leaves (Ficus elastica). Simplicia was extracted by maceration method, using 96% ethanol solvent for 3x24 hours and partitioned with a mixture of 96% ethanol - aquadest (2:3) and ethyl acetate as a solvent. Determination of flavonoid content using UV-Vis spectrophotometry method , with a maximum wavelength of 438 nm, using quercetin as a comparison. The results of this research obtained that the total flavonoid content in the ethyl acetate fraction ofÂ rubber leaves (Ficus elastica) was an average of 74,345 mgQE/g fraction

UJI AKTIVITAS IMUNOGLOBULIN M (IgM) KELINCI JANTAN (Oryctolagus cuniculus) AKIBAT PENGARUH PEMBERIAN PRODUK MADU Asriani Suhaenah; Nurul Ilmi Ainun Nissa
As-Syifaa Jurnal Farmasi Vol 5, No 2 (2013): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

The objective was to study the effect of natural pure honey on the immunoglobulin M (IgM) antibody activity against sheep red blood cells (SRBCs) antigen ini male rabbit (Oryctolagus cuniculus) using the hemoagglutination method. Three different honey products with 2,1 ml/kg body weight given orally twice a day for 5 days. Then each animal was injected intraperitoneally with 2,8 ml of 2% SRBCs. At day 7 after the immunization, serum were collected from the blood samples to know which highest dilution value of rabbit serum still showing agglutination reaction. The result of the the statistical analysis using the Complete Random Device ( CRD) method and than continued with the Duncan’s Multiple Range Test (DMRT) method shows that the administration of three different honey products significantly increase Immunoglobulin M (IgM) activity against SRBCs. Key words : Honey, Hemaglutination, Rabbit

UJI AKTIVITAS PENGHAMBATAN ENZIM α-GLUKOSIDASE EKSTRAK ETANOL BIJI BUAH ALPUKAT SANGRAI (Persea americana Mill.) SECARA IN VITRO St. Maryam Maryam; Asriani Suhaenah; Nurul Fadhillah Amrullah
As-Syifaa Jurnal Farmasi Vol 12, No 1 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

It is known that the seeds of avocado (Persea americana Mill.) are one part of the avocado widely used to treat various diseases, including diabetes. Based on the previous research, avocado seeds contain flavonoids with the potency as inhibitors of the enzyme α-glucosidase. The research aimed to determine the potency of ethanol extracted by meceration using 96% ethanol. The inhibitory activity was assayed using ELISA (Enzyme-Linked Immunosorbant Assay) reader measured at the wavelength of 405 with an acarbose comparator. The results showed that the ethanol extract of avocado seeds had an inhibitory activity included in the active category based on IC50 value of 34.300 µg/mL. Meanwhile, the acarbose had inhibition activity included in the very active category with an IC50 value of 0.253 µg/mL.

PENENTUAN NILAI SPF (SUN PROTECTING FACTOR) EKSTRAK ETANOL JAMUR KANCING (Agaricus bisporus) SECARA IN VITRO DENGAN METODE SPEKTROFOTOMETRI UV-VIS Asriani Suhaenah; Masdiana Tahir; Nasra Nasra
As-Syifaa Jurnal Farmasi Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Chronic exposure to ultraviolet light from the sun will cause changes in skin structure and oxidative stress on the skin. The effects can be in the form of acute changes such as erythema, pigmentation and photosensitivity, as well as long-term effects of premature aging and skin damage. Sun Protection Factor (SPF) is a universal indicator that explains the effectiveness of a product or substance that is UV protection. Natural ingredients that can be used as UV protection are button mushrooms (Agaricus bisporus). This study aims to determine UV light protection activity in the ethanol extract of button mushrooms (Agaricus bisporus) based on the SPF values analyzed by UV-Vis spectrophotometry at wavelengths of 290-320 nm. The results showed that at concentrations of 1% and 2% had a medium SPF category with SPF values of 17,762 and 28,643. For concentrations of 3% and 4% it has a high SPF category with SPF values of 30,592 and 31,325. The higher the concentration used, the better the SPF value.

PENGARUH VARIASI KONSENTRASI CAIRAN PENYARI ETANOL TERHADAP KADAR POLIFENOL PADA DAUN BIDURI (Calotropis gigantea L.) Asriani Suhaenah
As-Syifaa Jurnal Farmasi Vol 8, No 2 (2016): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Effect of ethanol concentration variations on levels of polyphenols in the Biduri leaves extract (Calotropis gigantea L.), with the aim to determine the concentration of ethanol that produce high levels of polyphenols maximum on Biduri leaves extract (Calotropis gigantea L.). The method used in the form of laboratory experimental method, which leaves Biduri (Calotropis gigantea L.) is made in the form of extracts by using a variation of ethanol that is 50% ethanol, 70% and 96%, then the variation of the extract polyphenols quantitative test conducted using standard gallat acid and Folin -ciocalteau reagen with UV-VIS spectrophotometry method. The results of quantitative analysis by UV-VIS spectrophotometry method at the maximum wavelength 730 nm, obtained polyphenol content of 50% ethanol to extract mgGAE 11.14 / gram extract, 70% ethanol extract mg GAE 16.20 / gram extract, and 96% ethanol extract 11 , 72 mgGAE / gram of extract. Maximum levels of polyphenols contained in the ethanol extract with a concentration of 70%. Based on statistical analysis, the results obtained polyphenol content of ethanol Biduri leaves extract (Calotropis gigantea L.) with the third variation of the concentration that is 50%, 70%, and 96% were significantly different.

PENETAPAN KADAR FLAVONOID FRAKSI ETIL ASETAT DAUN KARET KEBO (Ficus elastica) DENGAN METODE SPEKTROFOTOMETRI UV-VIS Asriani Suhaenah; Mamat Pratama; A.Hesti Wulandasari Amir
As-Syifaa Jurnal Farmasi Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i1.767

Rubber plant (Ficus elastica) is a plant that has been widely used as traditional medicine. The leaves of this plant are used as medicine for coughing up blood, laxative urine, relieving pain and improving blood circulation. Various kinds of properties and benefits of the rubber plant (Ficus elastica) cannot be separated from the compounds contained in it such as saponins, polyphenols, and flavonoids. The purposes of this research is to determine the flavonoid total content in the ethyl acetate fraction of the rubber leaves (Ficus elastica). Simplicia was extracted by maceration method, using 96% ethanol solvent for 3x24 hours and partitioned with a mixture of 96% ethanol - aquadest (2:3) and ethyl acetate as a solvent. Determination of flavonoid content using UV-Vis spectrophotometry method , with a maximum wavelength of 438 nm, using quercetin as a comparison. The results of this research obtained that the total flavonoid content in the ethyl acetate fraction of rubber leaves (Ficus elastica) was an average of 74,345 mgQE/g fraction.

POTENSI DAUN PURING (Codiaeum variegatum) DALAM MENYERAP LOGAM TIMBAL (PB) DENGAN METODE SPEKTROFOTOMETRI SERAPAN ATOM (SSA) Asriani Suhaenah; St. Maryam; Gusmiati Gusmiati
As-Syifaa Jurnal Farmasi Vol 12, No 1 (2020): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

One type of pollution that must be taken into concern is lead metal (Pb) as an element that is harmful to humans. Croton leaves contain tannin chemical compounds that able to bind lead (Pb). The research aimed to determine to potency of croton leaves as an adsorbent of lead (Pb). The research used a metal content measurement method based on the adsorption of croton leaves by atomic absorption spectrophotometry (AAS). The results showed that the absorption of lead was based on 3 gram concentrations in the samples, namely sample (1) 0.1181 gram of 1.9991 µg/g, sample (2) 0.3179 gram of 0.0871 µg/g and sample (3) 0.5117 gram of 0.2171 µg/g. in the use of parameter of the sample concentration it is indicated that at mass 0.1181 gram, the lead metal content showed a maximum absorption of 1.9991 µg/g sample.

AKTIVITAS ANTIOKSIDAN FUNGI ENDOFIT HERBA KROKOT (Portulaca oleracea L.) Siska Nuryanti; Asriani Suhaenah; Rachmat Faisal Syamsu; Rini Andriani
As-Syifaa Jurnal Farmasi Vol 15, No 1 (2023): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v15i1.966

Purslane herb (Portulaca oleracea L.) is one of the plants that is considered as a valuable plant in the pharmaceutical world for the future because of its antioxidant content and high nutritional value. Endophytic fungi can produce secondary metabolites that have activities similar to those produced by their host plants, where these metabolites have medicinal potential. In previous studies, it was found that the ethyl acetate extract of endophytic fungi had antidiabetic activity in the α-glucosidase enzyme inhibition test. This research aims todetermine the antioxidant activity of the ethyl acetate extract of the endophytic fungus of purslane herb (Portulaca oleracea L.) using the Test method1,1-diphenyl-2-picrylhydrazyl(DPPH). Purslane herbaceous endophytic fungus isolate (Portulaca oleracea L.) code FEK purified for 3 days. Then, fermented using MYB medium for 21 days. After that, extracted to become a thick extract. Furthermore, the DPPH test was carried out using a vitamin C comparison solution. Based on the IC50 value of the ethyl acetate extract of the endophytic fungus of purslane herb code FEK, it was found to be 64.26 μg/mL which is a relatively strong antioxidant activity

SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIOKSIDAN FRAKSI ETIL ASETAT DAUN KARET KEBO (Ficus elastica) DENGAN MENGGUNAKAN METODE PEREDAMAN RADIKAL BEBAS DPPH (2,2-Diphenyl-1- Picrylhydrazil) Asriani Suhaenah; Siska Nuryanti; Zainal Abidin; Hexatrianto Fatul Rahman
As-Syifaa Jurnal Farmasi Vol 15, No 1 (2023): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v15i1.935

Free radicals are a form of reactive oxygen compounds, compounds that have unpaired electrons. Free radicals are independent atoms, molecules or compounds that have unpaired electrons, and therefore are highly reactive and unstable. Antioxidants are compounds that can slow down the oxidation process of free radicals. Ficus is a species that is rich in polyphenolic compounds, such as flavonoids which are strong antioxidants which can help in the prevention and treatment of various diseases caused by oxidative stress. The purpose of this study was to determine the value of antioxidant activity in the ethyl acetate fraction of kebo rubber leaves (Ficus elastica) using the DPPH (2,2-Diphenyl-1-Picrylhydrazil) free radical scavenging method based on the IC50 value. Based on the research results, it was found that the ethyl acetate fraction of kebo rubber leaves (Ficus elastica) contained flavonoids, phenolics, tannins and saponins and had antioxidant activity with an IC50 value of 70.74 µg/mL and included in the strong category

ANALISIS BAHAN KIMIA OBAT NATRIUM DIKLOFENAK DALAM SEDIAAN JAMU ASAM URAT YANG BEREDAR DI KOTA TIMIKA Maryam, St.; Suhaenah, Asriani; Rusniyanti, Rusniyanti
As-Syifaa Jurnal Farmasi Vol 15, No 2 (2023): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v15i2.1031

Uric acid herbs are an alternative that is still widely used by the community as an anti-inflammatory and pain reliever. The increasing public interest in returning to traditional medicine has prompted several manufacturers to add medicinal chemicals to their preparations to produce a faster and maximum therapeutic effect, one of which is diclofenac sodium. The study aimed to analyze the chemical ingredients of the uric acid herbs circulating in Timika City and to find out the level of diclofenac sodium contained therein. The method used is High Performance Liquid Chromatography (HPLC) with reverse phase, where the mobile phase is methanol: aquabidestilata (80:20) and the stationary phase is column C-18. Based on the test results, nine uric acid herbs showed positive results with retention times at the same value as diclofenac sodium. The content of diclofenac sodium obtained were code A herb of 4.135 mg/L, B herb : 36.300 mg/L, C herb : 18.530 mg/L, herb D : 473.219 mg/L, herb E : 40.991 mg/L, herb F : 77.165 mg/L L, herb G : 93.109 mg/L, herb H : 52.700 mg/L, and herb I : 297.123 mg/L. All herb samples tested were unfit for public use because they contained the chemical drug sodium diclofenac

Co-Authors A. Muflihunna, A. A.Hesti Wulandasari Amir Abd. Malik Abdul Malik Ahmad, Akstar Roskiana Ahmad, Aktsar Roskiana Aminah Aminah Aminah Aminah Amir, A. Hesti Wulandasari Aprianti, Tiara arifin, nurrizky afiah Aris, Arru'nnisa Ika Nur Ilmi Asri, Fitriani Bahari, Dita Wulan Bayu Putra, Bayu Damang, Irda Binti Dewi Yuliana Evatiara, Nur Fadlina Chany Saputri Gusmiati Gusmiati Hamsinah Hamsinah Harti Widiastuti Harti Widiastuti Hartina, Suki Hasrianti, Hasrianti Hasyim, Amita Hexatrianto Fatul Rahman Hudayanti, Andi Isti Inayanti Fatwa Ismail, Normawati Kamase, Jeni Mahmud, Nurul Faiza Mamat Pratama Mamat Pratama, Mamat Masdiana Tahir Masdiana Tahir, Masdiana mondo, zhafira anggraini Muammar Fawwaz Mujtahid, Izzatul Fikri Mulyana, Imam Dwiyan Muslimin Arafat Muzakkir Baits Muzakkir Baits, Muzakkir Nasra Nasra Nurlina Nurmaya Effendy Nurul Fadhillah Amrullah Nurul Ilmi Ainun Nissa Ohorela, Indah Kartika p, irmawan jamal Pratama, Shinta Indah Rachmat Faisal Syamsu Rais Razak, Rais renhoran, aulia azahra Rezky M, Mega Rini Andriani Riski Mentari Jahri Rizqi Nur Azizah Rusniyanti, Rusniyanti Rustam, Julis Tina Safitri, Ineks Safruddin Sandyna, Muhammad Ivan Saripa Indira Syahraini Latuconsina Saskia, Eka Putri Siska Siska Nuryanti Siska Nuryanti, Siska St Maryam, St St. Maryam St. Maryam Maryam St. Maryam, St. Tadjuddin Naid Virsa Handayani Yani, Indah Ahmad Yulinda Rahim Zainal Abidin Zainal Abidin

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