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All Journal HAYATI Journal of Biosciences JURNAL KIMIA SAINS DAN APLIKASI Jurnal Matematika & Sains Indonesian Journal of Pharmaceutical Science and Technology MPI (Media Pharmaceutica Indonesiana) INDONESIAN JOURNAL OF PHARMACY Acta Pharmaceutica Indonesia Journal of Medicine and Health Jurnal Ilmu Kefarmasian Indonesia Current Research on Biosciences and Biotechnology Narra J
Irda Fidrianny
Departemen Farmasi, Institut Teknologi Bandung
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Public Health

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Journal : Current Research on Biosciences and Biotechnology

 1 
Phytochemistry and pharmacological activities of Annona genus: A review Siti Kusmardiyani; Yohanes Andika Suharli; Muhamad Insanu; Irda Fidrianny
Current Research on Bioscences and Biotechnology Vol. 2 No. 1 (2020)
Publisher : Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/crbb.2020.2.1/KNIA7708

Abstract

Plants have been significantly used in traditional medicine by a variety of societies since antiquity, and knowledge of their safety, efficacy, and quality value can be developed through further research. The Genus Annona consisting of 119 species has been extensively researched and proven to have a diverse range of pharmacological activities such as antioxidant, antiulcer, antidiarrheal, and antiparasitic. This is because the Annona plants possess a great number of phytochemicals found in almost every part of the plant, which can be isolated to be developed into herbal medicine. Phytochemicals are classified into several classes, such as Annonaceous acetogenin, alkaloids, flavonoids, and essential oils. This article was created by collecting 137 research articles which discuss phytochemical compounds from 38 species and the pharmacological activity from 13 species.
Ethnopharmacognosy study, antioxidant activity, and chemical content in chicken bile Slamet Tuty; Irda Fidrianny; Sukrasno
Current Research on Bioscences and Biotechnology Vol. 3 No. 2 (2022)
Publisher : Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/crbb.2022.3.2/UFG27H3H

Abstract

The aim of this research was to study the ethnopharmacognosy, antioxidant activity, and chemical content of chicken bile. In addition, a bioactivity-guided isolation was also performed to identify compounds in chicken bile having antioxidant activity. Extraction was carried out by reflux method. Each extract was tested for its antioxidant activity using DPPH and CUPRAC methods. Fractionation was performed on selected extract, namely ethyl acetate extract, using vacuum liquid chromatography and subfraction using preparative TLC method and classical column chromatography (CCC). Compound 1 was characterized and identified by NMR, compound 2 was characterized and identified by LC-MS/MS and NMR, subfraction 7 was characterized by GC-MS. The result of the antioxidant activity of ethanol extract of chicken bile using the DPPH method (IC 50: 46.64 g/mL), ethyl acetate extract (IC 50: 69.99 g/mL), n-hexane extract (IC 50: 71.65 g/mL, fraction 15-17 (IC 50: 88.77 g/mL) showed strong antioxidant, whereas by CUPRAC method all extracts (EC 50: 69.90, EC 50: 80.28, EC 50: 70.40) and fraction (EC 50: 64.53) are strong antioxidants. The result of identification of compound 1 by NMR was identified as cholesterol, identification of compound 2 by LC-MS/MS was (E)-hexadecyl-ferulate and subfraction 7 which was identified by GC-MS produced dominant compounds, namely oleic acid, n-hexadecanoic acid, octadecanoic acid and palmitoleic acid. In conclusion, extract, fraction 15-17 and subfraction of chicken bile have antioxidant activity where the active antioxidant compound is a phenol group compound, namely (E)-hexadecyl-ferulate. The other chemical constituents found in chicken bile are, oleic acid, n-hexadecanoic acid, octadecanoic acid, and palmitoleic acid.
Co-Authors - Satrialdi . Elfahmi Afrillia Nuryanti Garmana Afrillia Nuryanti Garmana Afrillia Nuryanti Garmana Amanda, Patricia Andreanus A Soemardji Andreanus A Soemardji Annisa Rahman Ardian Baitariza Ardian Baitariza Ardian Baitariza, Ardian Arsul, Muhammad Ikhlas Baitariza, Ardian Choirunnisa, Atina Rizkiya Darijanto, Sasanti Tarini Dinda Prasetya Elin Yulinah Elin Yulinah Sukandar Elin Yulinah Sukandar Elin Yulinah Sukandar Ellis Siti Zahidah Fadhilah, Syifa Fitria, Alfiyani Fitriansyah, Sani Nurlaela Hartanti, Rika HENI RACHMAWATI I Ketut Adnyana IGNA Supradja Iwo, Maria I. Jessie Sofia Pamudji Jessie Sofia Pamudjie Jessie Sofia Pamudjie, Jessie Sofia Komar Ruslan Komar Ruslan Wirasutisna Komar Ruslan Wirasutisna Kosasih Padmawinata Leonny Yulita Hartiadi Meutia Faradilla, Meutia Muhamad Insanu Muhamad Insanu Nia K Sari Pamudji, Jessie Sofia Patricia Amanda Pramastya, Hegar Prasetya, Dinda Prihantini, Malinda Raveendaran, Narmmatha Regiana, Zhafira Amalia Rika Hartati Rika Hartati Rizaldy, Defri Rizka Triani Ruslan, Komar Sasanti Tarini Darijanto Sasanti Tarini Darijanto Sasanti Tarini Darijanto, Sasanti Tarini Satrialdi, - Shelvi E. Suherman Shelvi E. Suherman, Shelvi E. Sienny Wijaya Siti Kusmardiyani Slamet Tuty Soediro Soetarno Sukandar, Elin Yulinah Sukrasno Tri Suciati Triani, Rizka Wijaya, Sienny Yohanes Andika Suharli Yundari, Yundari Yuniarto, Ari Zahidah, Ellis Siti