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All Journal Jurnal Pengolahan Hasil Perikanan Indonesia Jurnal Ilmu dan Teknologi Kelautan Tropis Alotrop Jurnal Pendidikan dan Ilmu Kimia Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology Jurnal Sosial Ekonomi Kelautan dan Perikanan JURNAL PERIKANAN TROPIS Jurnal Laot Ilmu Kelautan Marine Kreatif Journal of Aceh Aquatic Sciences Nawadeepa: Jurnal Pengabdian Masyarakat
Mohamad Gazali
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Public Health Social Sciences Transportation Other

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Aktivitas inhibisi tirosinase ekstrak etanol rumput laut Ulva lactuca secara in vitro: In vitro tyrosinase inhibitory activity of ethanol extract of seaweed Ulva lactuca Gazali, Mohamad; Suhardani, Mila Novalita; Husni, Amir; Nurjanah, Nurjanah; Zuriat, Zuriat; Hasanah, Uswatun; Syafitri, Rina
Jurnal Pengolahan Hasil Perikanan Indonesia Vol. 27 No. 7 (2024): Jurnal Pengolahan Hasil Perikanan Indonesia 27(7)
Publisher : Department of Aquatic Product Technology IPB University in collaboration with Masyarakat Pengolahan Hasil Perikanan Indonesia (MPHPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17844/jphpi.v27i7.53399

Abstract

Ulva lactuca kaya senyawa bioaktif yang bermanfaat bagi manusia dan organisme lainnya. Tujuan penelitian ini adalah untuk menentukan aktivitas inhibisi tirosinase pada ekstrak etanol rumput laut U. lactuca secara in vitro. Penelitian ini dilakukan secara bertahap, yaitu proses maserasi U. lactuca dengan pelarut etanol. Ekstrak difraksinasi cair-cair dengan pelarut n-heksana, kloroform, dan air. Ekstrak etanol dan fraksi diuji total fenol, total flavonoid, dan aktivitas inhibisi tirosinase. Nilai total fenol dan flavonoid tertinggi didapatkan dari fraksi n-heksana dengan nilai 9,43±0,27 mgGAE/g dan 9,20±0,49 mgQE/g. Aktivitas inhibisi tirosinase tertinggi diperoleh dari fraksi n-heksan dengan nilai IC50 127,74±6,47 µg/mL. Senyawa aktif yang berperan penting dalam aktivitas inhibisi tirosinase pada ekstrak etanol dan fraksi n-heksana meliputi kalkon, asam ferulat, asam 4-nitrocinamat, asam 4-aminobenzoat, derivat 2TMS, asam 4-hidroksibenzoat, 4-tert-butylfenol, 1-tetradekanol, ester metil asam n-heksadekanoat, asam palmitat, 2-(2-Aminofenil)-1H-benzimidazol, dan asam 5-metilsalisilat. Fraksi n-heksana U. lactuca dapat digunakan sebagai inhibitor tirosinase alami.
Antioxidant and Anti-Arthritic Activities of Green Seaweed Halimeda tuna Methanolic Extract Gazali, Mohamad; Fatimah, Aden Nurin; Husni, Amir; Nurjanah, Nurjanah; Zuriat, Zuriat; Syafitri, Rina
Squalen, Buletin Pascapanen dan Bioteknologi Kelautan dan Perikanan Vol 19, No 1 (2024): May 2024
Publisher : :Agency for Marine and Fisheries Research and Human Resources, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15578/squalen.841

Abstract

Seaweed contains various bioactive compounds rich in pharmacological potentials, such as antioxidants and anti-arthritic. This study aims to determine the antioxidant and anti-arthritic activities of the methanolic extract of Halimeda tuna. Halimeda tuna samples were extracted using the maceration method and methanol. The methanol extract was tested for antioxidant (2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP)) and anti-arthritic activity using denatured bovine serum albumin (BSA). The methanol extract was also subjected to phytochemical and Gas Chromatography-Mass Spectrometry (GC-MS) analysis. Research results revealed that the extract yield was 0.50 ± 0.06%. Phytochemical analysis showed that H. tuna methanolic extract contained flavonoids, steroids, and alkaloids. GC-MS analysis showed that H. tuna methanolic extract contained steroids, fatty alcohols, and fatty acids. The antioxidant activity tests revealed an IC50 value of 299.98 ± 121.15 ppm and a FRAP value of 200.02 ± 8.50 M/g, categorized as a weak antioxidant. Anti-arthritic activity of H. tuna methanolic extract showed an IC50 value of 877.29 ± 209.84 ppm. The anti-arthritic activity of H. tuna methanolic extract was lower than sodium diclofenac as a standard drug. The extract of H. tuna has antioxidant and anti-arthritic activities; hence, further exploration is needed as an alternative potential in the pharmacological field.
Program Pengenalan Metode Ekstraksi Sargassum sp Sebagai Fitoimunostimulan Bagi Ikan Nila di Balai Perikanan Budidaya Air Payau Ujong Batee, Aceh Besar Zuriat, Zuriat; Gazali, Mohamad; Syafitri, Rina; Zuraidah, Syarifah; Amarullah, T; Wahyuni, Sri
Marine Kreatif Vol 8, No 2 (2024): Marine Kreatif
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/mk.v8i2.10247

Abstract

Alga cokelat Sargassum sp memiliki potensi untuk dapat dijadikan sebagai sumber pakan antiobiotik bagi komoditas budidaya ikan nila. Sargassum sp merupakan salah satu organisme laut yang tersebar pada zona intertidal pada kedalam 1-3 m yang masih tembus penetrasi Cahaya matahari. Tujuan dari pelaksanaan pengabdian masyarakat adalah untuk memperkenalkan metode ekstraksi Sargassum sp sebagai fitoimunostimulan bagi ikan nila di Balai Perikanan Air Payau Ujong Batee, Aceh Besar. Metode pelaksanaan kegiatan pengabdian masyarakat meliputi sosialisasi, penyerahan bahan baku Sargassum sp, dan pengenalan invensi paten sederhana dan hasil riset kepada stakeholder. Pelaksanaan kegiatan pengabdian kepada masyarakat dilaksanakan dengan melibatkan stakeholder memberikan dampak dan respon positif untuk meningkatkan produktivitas ikan nila (Oreochromis niloticus). Outcomes yang diharapkan dalam kegiatan ini adalah implementasi paten sederhana berkaitan dengan metode ekstraksi Sargassum sp sebagai fitoimmunostimulan pada ikan nila (O. niloticus).
SYSTEMATIC LITERATURE REVIEW OF TRENDS AND DEVELOPMENT IN ANTIHYPERTENSIVE EFFECT OF SEAWEED RESEARCH: SCIENTOMETRIC ANALYSIS Mohamad Gazali; Yosie Andriani; Jasnizat Saidin; Noraznawati Ismail
ALOTROP Vol. 8 No. 2 (2024): Alotrop 2024
Publisher : University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/alo.v8i2.36875

Abstract

Hypertension is the most alarming disease that causes cardiovascular risk for human health Worldwide. Thus, the author has explored marine natural marine macroalgae that possess antihypertension activity to lower blood pressure. Marine macroalgae or seaweed tropical marine organisms from marine biodiversity that are distributed widely in the subtropic and tropical oceans. Marine macroalgae have a significant role in preventing hypertension risk with a unique biochemical compound that is not contained in a terrestrial plant. However, antihypertension of seaweed research using scientometric analysis is limited. This study collected scientific information from relevant literature to determine the recent development and trends regarding antihypertension of seaweed research Worldwide. Many researchers, academia, and practitioners will have a wide understanding of the recent novelty finding in seaweed prospect to prevent antihypertension disease with a scientometric analysis approach to interpret data using CiteSpace. The literature review using scientometric analysis regarding antihypertension of seaweed research from 1991 until 2022. The result showed Suetsuna K is the most influential author (sigma score =1.52, centrality score =0.24 and degree score =51). Advances in Food and Nutrition Research is the leading journal. The most popular keywords in common cluster related antihypertension of seaweed research area are seaweed, hypertension, algae, in vitro, and dietary fiber. On the other hand, various stakeholders need to know the development and trends of a marine drug for antihypertensive effect from various seaweeds or marine macroalgae.
Tyrosinase Inhibitory Activity of Methanolic Extract and Fractions from Green Seaweed Ulva lactuca Gazali, Mohamad; Maknun, Fazidatul Lu’luil; Husni, Amir; Nurjanah, Nurjanah; Nursid, Muhammad; Hasanah, Uswatun; Zuriat, Zuriat; Syafitri, Rina
Squalen, Buletin Pascapanen dan Bioteknologi Kelautan dan Perikanan Vol 20, No 1 (2025): May 2025
Publisher : :Agency for Marine and Fisheries Research and Human Resources, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15578/squalen.915

Abstract

Ulva lactuca, a widely available green seaweed, has demonstrated promising bioactivity as a tyrosinase inhibitor. This study aimed to evaluate the tyrosinase inhibitory activity of U. lactuca extracts and identify the active compounds responsible. The seaweed was extracted using methanol via maceration, followed by partitioning with hexane, chloroform, and water. Total phenolic and flavonoid contents were determined using UV-VIS spectrophotometry, and tyrosinase inhibition was assessed in vitro. Among the tested fractions, the hexane fraction exhibited the highest tyrosinase inhibitory activity with an IC50 value of 584.34 ± 35.07 µg/mL, classifying it as an active inhibitor. Although this activity was weaker than kojic acid (IC50 = 11.07 ± 0.86 µg/mL), the hexane fraction showed relatively high phenolic (11.66 ± 0.53 mg GAE/g) and flavonoid (9.75 ± 0.30 mg QE/g) contents. Gas Chromatography-Mass Spectrometry (GC-MS) analysis identified several bioactive compounds, notably 2,4-dimethoxycinnamic acid, chalcone, and derivatives such as 2,6-dihydroxybenzoic acid and phloretin. These findings highlight the potential of U. lactuca, particularly its hexane fraction, as a source of natural tyrosinase inhibitors. This opens avenues for its application in the pharmaceutical and cosmetic industries, especially in formulations targeting hyperpigmentation and skin brightening.
Antifouling properties of green seaweed Halimeda opuntia from the Coast of Aceh, Indonesia: Sifat antifouling Halimeda opuntia dari Pesisir Aceh, Indonesia Gazali, Mohamad; Ismail, Noraznawati; Saidin, Jasnizat; Bakar, Kamariah; Siong, Julius Yong Fu
Jurnal Pengolahan Hasil Perikanan Indonesia Vol. 28 No. 6 (2025): Jurnal Pengolahan Hasil Perikanan Indonesia 28(6)
Publisher : Department of Aquatic Product Technology IPB University in collaboration with Masyarakat Pengolahan Hasil Perikanan Indonesia (MPHPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17844/jphpi.v28i6.63699

Abstract

Biofouling merupakan tantangan yang dihadapi dalam sektor maritim dan mendorong para peneliti untuk mengeksplorasi secara berkelanjutan dengan mencari solusi berupa antifouling yang ramah lingkungan dan berasal dari organisme laut. Penelitian ini bertujuan menentukan konsentrasi terbaik ekstrak H. opuntia berdasarkan aktivitas antifouling. Metode penelitian ini meliputi uji antibiofilm, sitotoksisitas, antibakteri, anti-quorum sensing, dan uji in situ. Hasil penelitian menunjukkan bahwa ekstrak metanol H. opuntia memiliki aktivitas antibiofilm lebih tinggi dengan nilai IC50 sebesar 0,020 mg/mL. Uji sitotoksisitas menunjukkan toksisitas terendah terhadap sel L6, dengan nilai IC50 sebesar 70,79 µg/mL. Secara mekanistik, ekstrak metanol H. opuntia tidak memiliki efek bakterisidal melawan bakteri Pseudomonas aeruginosa, tetapi dapat menghalangi mekanisme komunikasi bakteri melalui aktivitas quorum quenching, yang dibuktikan dengan pembentukan zona buram tidak berwarna dalam uji tersebut. Uji in situ yang dilakukan di perairan Pulau Redang dan Kuala Kemaman, Malaysia menunjukkan panel yang dilapisi dengan formulasi 5% H. opuntia menunjukkan kinerja antifouling yang superior selama tiga bulan percobaan, dengan tingkat penutupan fouling masing-masing sebesar 11,19% dan 9,10%. Penelitian selanjutnya diperlukan berkaitan dengan sifat antifouling dengan melakukan identifikasi senyawa aktif, evaluasi efektivitas jangka panjang, dan menentukan efisiensi biaya untuk produksi massal.
Freshwater Fish and Challenge of Supply Chain for Production Enhancement: West Southern Region of Aceh Province, Indonesia Zuriat, Zuriat; Amarullah, T; gazali, mohamad; Ali, M; Irham, Muhammad
Jurnal Sosial Ekonomi Kelautan dan Perikanan Vol 20, No 1 (2025): JUNI 2025
Publisher : Balai Besar Riset Sosial Eonomi Kelautan dan Perikanan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15578/jsekp.v20i1.13653

Abstract

This research aims to analyze the supply chain and marketing chain of freshwater fish in the West-Southern Region of Aceh Province, Indonesia. The research activities took place from May to July 2022, with data collection continuing in 2023. The determination of data collection locations used purposive methods, and data collection was conducted through survey methods. Data were obtained from fish traders in four  markets: Ujong Baroh Meulaboh Fish Market, Blang Pidie Market, Nagan Raya Market, and Krueng Sabe Fish Market. Data analysis was conducted descriptively. The research results indicate that the supply chain includes fish farmers, partner traders, collector traders, retailers, and consumers, and there are two supply chains based on regions: inter-insular and intra-region. The dominant types of freshwater fish supply are catfish and tilapia. Tilapia has a higher price compared to catfish. Tilapia is dominant in the Ujong Baroh market, while catfish is dominant in the Blang Pidie  market. It has become a substitute when sea fish are scarce or expensive in the market. Based on the value chain analysis, a margin ranging from 10% to 30% was obtained. Partner traders play a significant role in production activities and the supply chain due to cooperation in input-output factors. Challenges in the freshwater fish supply consist of seeds and feed, with seeds mostly supplied from outside West-South, accounting for more than 80%.. Addressing freshwater fish supply challenges in Southwest Aceh requires an integrated supply chain approach enhancing hatchery systems and fry distribution upstream, improving aquaculture infrastructure and feed subsidies at the production level, and establishing collection centers, cold storage, and modern markets in key districts to strengthen distribution, stabilize prices, and improve food security.
Eksplorasi Senyawa Bioaktif Alga Cokelat Sargassum sp. Agardh sebagai Antioksidan dari Pesisir Barat Aceh Gazali, Mohamad; Nurjanah, Nurjanah; Zamani, Neviaty P.
Jurnal Pengolahan Hasil Perikanan Indonesia Vol. 21 No. 1 (2018): Jurnal Pengolahan Hasil Perikanan Indonesia 21(1)
Publisher : Department of Aquatic Product Technology IPB University in collaboration with Masyarakat Pengolahan Hasil Perikanan Indonesia (MPHPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (254.776 KB) | DOI: 10.17844/jphpi.v21i1.21543

Abstract

Alga cokelat merupakan salah satu jenis makroalga laut yang mendominasi kawasan pesisir Barat Aceh. Penelitian ini bertujuan untuk melakukan eksplorasi senyawa bioaktif alga cokelat Sargassum sp. sebagai sumber antioksidan. Penelitian dilakukan secara deskriptif. Pengujian terdiri dari analisis proksimat, senyawa aktif, total fenol, aktivitas antioksidan metode DPPH dan perhitungan rendemen ekstrak. Hasil penelitian menunjukkan komposisi kimia yang paling dominan terdiri dari kadar abu 52,74% dan kadar karbohidrat 23,77%. Rendemen ekstrak Sargasuum sp. dengan pelarut etanol 0,565%, etil asetat 0,420% dan n-heksan 0,265%. Kadar total fenol etanol ektrak 563,22 mg GAE/g, etil asetat ekstrak 13,48 mg GAE/g, n-heksan ekstrak 30,610 mg GAE/g. Aktivitas antioksidan etanol ekstrak dengan IC50 = 239,51mg/L, etil asetat ekstrak 68,89 mg/L dan n-heksan ekstrak 148.16 mg/L. Ekstrak Sargassum sp. terdeteksi mengandung fenol, alkaloid dan triterpenoid.
Edukasi Pengelolaan Sampah Rumah Tangga Menjadi Ecobrick di Desa Cot Seumeureng Aceh Barat Rahma, Endah Anisa; Najmi, Nurul; Suriani, Mai; Oktavinanda, Giovanni; Gazali, Mohamad; Syafitri, Rina; Hasni, Jusnaini; Rahmatillah, Refanja
Nawadeepa: Jurnal Pengabdian Masyarakat Volume 2, No 2 (2023): June
Publisher : Pencerah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58835/nawadeepa.v2i2.174

Abstract

In Indonesia, plastic waste is the main source of the build up of garbage in landfill sites. It is also kinds of garbage that pollutes the environment because it is difficult to decompose in natural process. The problems occur in the society now is that they are unable to manage their waste effectively. If the problem is not managed properly, it will bring negative effects for the environment. This community services activity was held in Cot Seumeureng Village, West Aceh. The aim of this community service activity is to increase the society awareness on the importance of protecting and taking care of the environment in order to be clean and healthy and free of plastic waste. The methods used in this activity are the ecobrick management training and recycle it to be household appliances. The result of this activity is the increasing awareness of the society in managing the waste and recycle it using ecobrick and also to support the economy of the society in the area. Therefore, it can be concluded that plastic waste can help the community’s income by the use of plastic waste to be ecobricks and protect the environment from plastic waste.
Sosialisasi Perlindungan Satwa Liar Penyu Laut pada Siswa/Siswi SMKN 1 Panga, Aceh Jaya Mohamad Gazali; Masyumi Masyumi; T. Amarullah; Rina Syafitri; Taufiq Taufiq
Marine Kreatif Vol 10, No 1 (2026): Marine Kreatif
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/mk.v10i1.15312

Abstract

Inisiatif sosialisasi konservasi yang diimplementasikan di SMKN 1 Panga, Aceh Jaya, merepresentasikan strategi pendidikan lingkungan yang terstruktur untuk meningkatkan literasi ekologis, pemahaman kognitif, dan komitmen perilaku pro-konservasi pada peserta didik pendidikan menengah kejuruan. Program ini dirancang untuk mengkomunikasikan peran ekologis kunci penyu laut, mengidentifikasi tekanan antropogenik yang mengancam kelangsungan populasi, serta menegaskan urgensi tata kelola partisipatif berbasis masyarakat dalam melindungi habitat penetasan dan mencegah eksploitasi telur. Melalui pendekatan pedagogis multimodal yang mengintegrasikan penyampaian materi klasikal, media visual, diskusi terpandu, dan pembelajaran interaktif, inisiatif ini memosisikan konservasi penyu tidak semata sebagai imperatif biologis, melainkan sebagai tanggung jawab sosio-kultural yang integral bagi keberlanjutan komunitas pesisir. Intervensi ini memiliki justifikasi empiris mengingat transisi historis Aceh Jaya dari pola eksploitasi sumber daya menuju inisiatif konservasi berbasis komunitas, yang memerlukan pendidikan lingkungan berkelanjutan dan terkontekstualisasi. Dengan menyasar siswa SMK sebagai calon pemangku kepentingan sektor kelautan dan pesisir, sosialisasi ini bertujuan membentuk generasi yang memiliki literasi lingkungan komprehensif, agensi konservasi aktif, serta kapasitas untuk mendukung pengelolaan wilayah pesisir yang berkelanjutan. Lebih lanjut, program ini menjembatangi pembelajaran formal dengan praktik konservasi lapangan, mendorong pembentukan intensi perilaku dan internalisasi norma positif terhadap perlindungan penyu. Secara keseluruhan, model ini mengonfirmasi bahwa sosialisasi konservasi berbasis sekolah merupakan pendekatan strategis dan terukur untuk menumbuhkan environmental stewardship lintas generasi serta memperkuat tata kelola sumber daya kelautan berbasis partisipasi masyarakat di wilayah pesisir Indonesia.
Co-Authors Afrizal Hendri Alfarisi, Irnu Ali, M Amarullah, T Amarullah, Teuku Amir Husni Bakar, Kamariah Beginer Subhan Deri Anggraini Endah Anisa Rahma, Endah Anisa Eri Safutra Farah Salsabila, Farah Fatimah, Aden Nurin Hasni, Jusnaini Hayatun Nufus Hermansyah Amir, Hermansyah Ismail, Noraznawati Jasnizat Saidin Khairul Samuki Mai Suriani Maknun, Fazidatul Lu’luil Mardalena, Selvi Masyumi Masyumi Muhammad Agam Thahir Muhammad Irham Muhammad Nurdin Muhammad Nursid Mulyono S. Baskoro N. Nurjanah Nabila Ukhty NEVIATY PUTRI ZAMANI Noraznawati Ismail Nurjanah Nurul Najmi Oktavinanda, Giovanni Rahmatillah, Refanja Rina Syafitri Rina Syafitri, Rina Ropita, Ropita Saidin, Jasnizat Siong, Julius Yong Fu Sri Wahyuni Suhardani, Mila Novalita Syarifah Zuaridah Syarifah Zuraidah T. Amarullah Taufiq Taufiq Teuku Amarullah Uswatun Hasanah Yahya, Rodhiyah Yosie Andriani Zuriat Zuriat Zuriat Zuriat Zuriat, Zuriat